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We report a case of recurrent multi-drug resistant <jats:italic>Campylobactor jejuni<\/jats:italic> bloodstream infections in a Bruton\u2019s X-linked agammaglobulinemia patient with prolonged ertapenem treatment. The isolate from the fifth recurrence developed carbapenem resistance, which is associated with mutations in a porin gene <jats:italic>porA<\/jats:italic>, and promoter changes and duplication of chromosomal bla<jats:italic>OXA-61<\/jats:italic> gene. Combination therapy using cefepime and doxycycline (later switched to moxifloxacin) cleared the infection.<\/jats:p>","DOI":"10.1007\/s10096-024-04937-1","type":"journal-article","created":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T14:01:40Z","timestamp":1727186500000},"page":"2459-2463","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Carbapenem resistant Campylobacter jejuni bacteremia in a Bruton\u2019s X-linked agammaglobulinemia patient"],"prefix":"10.1007","volume":"43","author":[{"given":"Ran","family":"Zhuo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramee L.","family":"Younes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Ward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shangxin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,24]]},"reference":[{"key":"4937_CR1","doi-asserted-by":"crossref","unstructured":"Najjar I, Paluca F, Loukidis K, Tarr PE (2020) Recurrent Campylobacter enteritis in patients with hypogammaglobulinemia: review of the literature. 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