{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T02:55:19Z","timestamp":1764557719363,"version":"3.37.3"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T00:00:00Z","timestamp":1728604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T00:00:00Z","timestamp":1728604800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1007\/s10096-024-04964-y","type":"journal-article","created":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T07:02:09Z","timestamp":1728630129000},"page":"2419-2427","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of clinical and laboratory characteristics of COVID-19 and influenza in hospitalized children"],"prefix":"10.1007","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4671-6082","authenticated-orcid":false,"given":"Zeynep","family":"Sava\u015f \u015een","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5127-4720","authenticated-orcid":false,"given":"T\u00fcrkan","family":"Ayd\u0131n Teke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0083-0587","authenticated-orcid":false,"given":"Rumeysa","family":"Yalcinkaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8042-9119","authenticated-orcid":false,"given":"Suna","family":"\u00d6zdem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6373-2589","authenticated-orcid":false,"given":"R\u00fcveyda","family":"G\u00fcm\u00fc\u015fer Cinni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2687-1544","authenticated-orcid":false,"given":"Hasibe G\u00f6k\u00e7e","family":"\u00c7inar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8548-4144","authenticated-orcid":false,"given":"Zeynelabidin","family":"\u00d6zt\u00fcrk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1057-1531","authenticated-orcid":false,"given":"G\u00f6ktu\u011f","family":"\u00d6zdemir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0862-3961","authenticated-orcid":false,"given":"Meltem","family":"Ak\u00e7aboy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meltem","family":"Polat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ay\u015fe","family":"Kaman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8374-095X","authenticated-orcid":false,"given":"Fatma Nur","family":"\u00d6z","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,10,11]]},"reference":[{"unstructured":"World Health Organization (WHO) Coronavirus (COVID-19) Dashboard (2024) https:\/\/data.who.int\/dashboards\/covid19\/cases. Accessed 14 April 2024","key":"4964_CR1"},{"issue":"9","key":"4964_CR2","doi-asserted-by":"publisher","first-page":"4107","DOI":"10.1002\/jmv.27817","volume":"94","author":"S Tasar","year":"2022","unstructured":"Tasar S, Karadag-Oncel E, Yilmaz-Ciftdogan D et al (2022) Influenza is more severe than our newest enemy (COVID-19) in hospitalized children: experience from a Tertiary Center. J Med Virol 94(9):4107\u20134114","journal-title":"J Med Virol"},{"unstructured":"Centers for Disease Control and Prevention, COVID Data Tracker (2024) https:\/\/covid.cdc.gov\/covid-data-tracker\/#pediatric-data. CDC. Accessed 15 April 2024","key":"4964_CR3"},{"key":"4964_CR4","doi-asserted-by":"publisher","first-page":"155478","DOI":"10.1016\/j.cyto.2021.155478","volume":"142","author":"BM Liu","year":"2021","unstructured":"Liu BM, Martins TB, Peterson LK, Hill HR (2021) Clinical significance of measuring serum cytokine levels as inflammatory biomarkers in adult and pediatric COVID-19 cases: a review. Cytokine 142:155478","journal-title":"Cytokine"},{"issue":"9","key":"4964_CR5","doi-asserted-by":"publisher","first-page":"e2020495","DOI":"10.1001\/jamanetworkopen.2020.20495","volume":"3","author":"X Song","year":"2020","unstructured":"Song X, Delaney M, Shah RK et al (2020) Comparison of clinical features of COVID-19 vs Seasonal Influenza A and B in US children. JAMA Netw Open 3(9):e2020495","journal-title":"JAMA Netw Open"},{"unstructured":"Centers for Disease Control and Prevention (2022) Influenza: People at higher risk of flu complications. cdc.gov\/flu\/highrisk\/index.htm. Accessed 2 September 2022","key":"4964_CR6"},{"key":"4964_CR7","doi-asserted-by":"publisher","first-page":"623","DOI":"10.3325\/cmj.2021.62.623","volume":"6","author":"AB Shimol","year":"2021","unstructured":"Shimol AB, Dahan S, Alon N et al (2021) Can laboratory evaluation differentiate between coronavirus disease-2019, influenza, and respiratory syncytial virus infections? A retrospective cohort study. Croat Med J 6:623\u2013629","journal-title":"Croat Med J"},{"key":"4964_CR8","doi-asserted-by":"publisher","first-page":"1342","DOI":"10.1001\/jama.2020.14661","volume":"324","author":"DA Solomon","year":"2020","unstructured":"Solomon DA, Sherman AC, Kanjilal S (2020) Influenza in the COVID-19 era. JAMA 324:1342\u20131343","journal-title":"JAMA"},{"doi-asserted-by":"crossref","unstructured":"Y\u0131lmaz K, \u015een V, Aktar F et al (2021) Does Covid-19 in children have a milder course than Influenza? Int J Clin Pract 75(9): e 14466","key":"4964_CR9","DOI":"10.1111\/ijcp.14466"},{"unstructured":"Centers for Disease Control and Prevention, National Center for Immunization an Respiratory Diseases (NCIRD) (2023) U.S. Influenza Sruveillance: Purpose and Methods. https:\/\/www.cdc.gov\/flu\/weekly\/overview.htm. Last Reviewed 13 October 2023","key":"4964_CR10"},{"key":"4964_CR11","doi-asserted-by":"publisher","first-page":"2175","DOI":"10.1056\/NEJMoa0911530","volume":"362","author":"BJ Cowling","year":"2020","unstructured":"Cowling BJ, Chan KH, Fank VJ et al (2020) Comparative epidemiology of pandemic and Seasonal Influenza A in households. N Engl J Med 362:2175\u20132184","journal-title":"N Engl J Med"},{"unstructured":"American Academy of Pediatrics (2024) Coronavirus Disease 2019 (COVID-19). In: Kimberlin DW, Banerjee R, Banett ED, Lynfield R, Sawyer MH, eds. Red Book: 2024 Report of the Committee On Infectious Diseases. American Academy of Pediatrics 324\u2013332","key":"4964_CR12"},{"doi-asserted-by":"crossref","unstructured":"Dawood FS, Rao S (2023) Influenza Viruses. In: Long SS, Prober CG, Fischer M, Kimberlin DW (ed). Principles and Practice of Pediatric Infectious Diseases, 6th ed. Philadelphia, PA 19103\u2009\u2013\u20092899, by Elsevier, Inc 229, pp. 1205\u20131213.e5","key":"4964_CR13","DOI":"10.1016\/B978-0-323-75608-2.00229-9"},{"unstructured":"World Health Organization (WHO) (2020) COVID-19 case definition: Updated in Public health surveillance for COVID-19. WHO\/2019-nCoV\/Surveillance_Case_Definition\/2020.2. Accessed 16 December 2020","key":"4964_CR14"},{"key":"4964_CR15","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1186\/s12879-021-06068-w","volume":"21","author":"X Liu","year":"2021","unstructured":"Liu X, Li W, Zhang B et al (2021) Comparative study of hospitalized children with acute respiratory distress syndrome caused by SARS-CoV-2 and influenza virus. BMC Infect Dis 21:412\u2013421","journal-title":"BMC Infect Dis"},{"key":"4964_CR16","doi-asserted-by":"publisher","first-page":"676611","DOI":"10.3389\/fped.2021.676611","volume":"9","author":"A Laris-Gonz\u00e1lez","year":"2021","unstructured":"Laris-Gonz\u00e1lez A, Avil\u00e9s-Robles M, Dom\u00ednguez-Barrera C et al (2021) Influenza vs. COVID-19: comparison of clinical characteristics and outcomes in Pediatric patients in Mexico City. Front Pediatr 9:676611","journal-title":"Front Pediatr"},{"key":"4964_CR17","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1038\/s41579-021-00542-7","volume":"19","author":"T Flerlage","year":"2021","unstructured":"Flerlage T, Boyd DF, Meliopoulos V et al (2021) Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract. Nat Rev Microbiol 19:425\u2013441","journal-title":"Nat Rev Microbiol"},{"key":"4964_CR18","doi-asserted-by":"publisher","first-page":"452","DOI":"10.3390\/v13030452","volume":"13","author":"M Osman","year":"2021","unstructured":"Osman M, Klopfenstein T, Belfeki N et al (2021) A comparative systematic review of COVID-19 and Influenza. Viruses 13:452\u2013464","journal-title":"Viruses"},{"key":"4964_CR19","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1007\/s12519-021-00432-1","volume":"17","author":"AA Asseri","year":"2021","unstructured":"Asseri AA, Shati AA, Al-Qahtani SM et al (2021) Distinctive clinical and laboratory features of COVID-19 and H1N1 influenza infections among hospitalized pediatric patients. World J Pediatr 17:272\u2013279","journal-title":"World J Pediatr"},{"key":"4964_CR20","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1631\/jzus.B2000479","volume":"22","author":"Y Bai","year":"2021","unstructured":"Bai Y, Tao X (2021) Comparison of COVID-19 and influenza characteristics. J Zhejiang Univ Sci B 22:87\u201398","journal-title":"J Zhejiang Univ Sci B"},{"key":"4964_CR21","doi-asserted-by":"publisher","first-page":"2505","DOI":"10.1111\/jdv.16778","volume":"34","author":"Q Zhao","year":"2020","unstructured":"Zhao Q, Fang X, Pang Z et al (2020) COVID-19 and cutaneous manifestations: a systematic review. J Eur Acad Dermatol Venereol 34:2505\u20132510","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"4964_CR22","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.clinimag.2020.05.013","volume":"66","author":"S Behzad","year":"2020","unstructured":"Behzad S, Aghaghazvini L, Radmard AR et al (2020) Extrapulmonary manifestations of COVID-19: radiologic and clinical overview. Clin Imaging 66:35\u201341","journal-title":"Clin Imaging"},{"issue":"12","key":"4964_CR23","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1089\/jir.2020.0210","volume":"40","author":"BM Liu","year":"2020","unstructured":"Liu BM, Hill HR (2020) Role of host Immune and inflammatory responses in COVID-19 cases with underlying primary immunodeficiency: a review. J Interferon Cytokine Res 40(12):549\u2013554","journal-title":"J Interferon Cytokine Res"},{"issue":"1","key":"4964_CR24","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1002\/JLB.4MA0320-343R","volume":"108","author":"KS LeMessurier","year":"2020","unstructured":"LeMessurier KS, Rooney R, Ghoneim HE et al (2020) Influenza a virus directly modulates mouse eosinophil responses. J Leukoc Biol 108(1):151\u2013168","journal-title":"J Leukoc Biol"},{"doi-asserted-by":"crossref","unstructured":"Pormohammad A, Ghorbani S, Khatami A et al (2020) Comparison of influenza type A and B with COVID-19: a global systematic review and meta\u2010analysis on clinical, laboratory and radiographic findings. Rev Med Virol 31(3):e2179","key":"4964_CR25","DOI":"10.1002\/rmv.2179"},{"key":"4964_CR26","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/S2213-2600(20)30527-0","volume":"9","author":"L Piroth","year":"2021","unstructured":"Piroth L, Cottenet J, Mariet AS et al (2021) Comparison of the characteristics, morbidity, and mortality of COVID-19 and seasonal influenza: a nationwide, population-based retrospective cohort study. Lancet Respir Med 9:251\u2013259","journal-title":"Lancet Respir Med"},{"key":"4964_CR27","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1111\/all.14657","volume":"76","author":"YD Gao","year":"2021","unstructured":"Gao YD, Ding M, Dong X et al (2021) Risk factors for severe and critically ill COVID-19 patients: a review. Allergy 76:428\u2013455","journal-title":"Allergy"},{"key":"4964_CR28","doi-asserted-by":"publisher","first-page":"e137","DOI":"10.1097\/INF.0000000000003043","volume":"40","author":"K Graff","year":"2021","unstructured":"Graff K, Smith C, Silveira L et al (2021) Risk factors for severe COVID-19 in children. Pediatr Infect Dis J 40:e137\u2013e145","journal-title":"Pediatr Infect Dis J"},{"key":"4964_CR29","doi-asserted-by":"publisher","first-page":"e978","DOI":"10.1093\/cid\/ciaa1747","volume":"72","author":"AJ Zhang","year":"2021","unstructured":"Zhang AJ, Lee ACY, Chan JFW et al (2021) Coinfection by severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 virus enhances the severity of Pneumonia in Golden Syrian hamsters. Clin Infect Dis 72:e978\u2013e992","journal-title":"Clin Infect Dis"},{"key":"4964_CR30","doi-asserted-by":"publisher","first-page":"e993","DOI":"10.1093\/cid\/ciaa1810","volume":"72","author":"S Covin","year":"2021","unstructured":"Covin S, Rutherford GW (2021) Co-infection, SARS-CoV-2 and influenza: an evolving puzzle. Clin Infect Dis 72:e993\u2013e994","journal-title":"Clin Infect Dis"},{"issue":"3","key":"4964_CR31","doi-asserted-by":"publisher","first-page":"100036","DOI":"10.1016\/j.jcvp.2021.100036","volume":"1","author":"TL Dao","year":"2021","unstructured":"Dao TL, Hoang VT, Colson P et al (2021) Co-infection of SARS-CoV-2 and influenza viruses: a systematic review and meta-analysis. J Clin Virol Plus 1(3):100036","journal-title":"J Clin Virol Plus"},{"key":"4964_CR32","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1016\/j.ijid.2020.05.068","volume":"96","author":"S Ma","year":"2020","unstructured":"Ma S, Lai X, Chen Z et al (2020) Clinical characteristics of critically ill patients co-infected with SARS-CoV-2 and the influenza virus in Wuhan, China. Int J Infect Dis 96:683\u2013687","journal-title":"Int J Infect Dis"},{"issue":"11","key":"4964_CR33","doi-asserted-by":"publisher","first-page":"2870","DOI":"10.1002\/jmv.26163","volume":"92","author":"H Yue","year":"2020","unstructured":"Yue H, Zhang M, Xing L et al (2020) The epidemiology and clinical characteristics of co-infection of SARS-CoV-2 and influenza viruses in patients during COVID-19 outbreak. J Med Virol 92(11):2870\u20132873","journal-title":"J Med Virol"},{"issue":"4","key":"4964_CR34","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1093\/ije\/dyab081","volume":"50","author":"J Stowe","year":"2021","unstructured":"Stowe J, Tessier E, Zhao H et al (2021) Int J Epidemiol 50(4):1124\u20131133","journal-title":"Int J Epidemiol"},{"issue":"1","key":"4964_CR35","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1128\/JCM.01801-16","volume":"28","author":"B Liu","year":"2016","unstructured":"Liu B (2016) Universal PCR primers are critical for direct sequencing-based enterovirus genotyping. J Clin Microbiol 28(1):339\u2013340","journal-title":"J Clin Microbiol"},{"key":"4964_CR36","doi-asserted-by":"publisher","first-page":"113690","DOI":"10.1016\/j.jviromet.2019.113690","volume":"272","author":"B Liu","year":"2019","unstructured":"Liu B, Forman M, Valsamakis A (2019) Optimization and evaluation of a novel real-time RT-PCR test for detection of parechovirus in cerebrospinal fluid. J Virol Methods 272:113690","journal-title":"J Virol Methods"},{"issue":"12","key":"4964_CR37","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1016\/j.jmoldx.2020.10.003","volume":"22","author":"B Liu","year":"2020","unstructured":"Liu B, Totten M, Nematollahi S et al (2020) Development and evaluation of a fully automated Molecular Assay Targeting the mitochondrial small subunit rRNA gene for the detection of Pneumocystis Jirovecii in Bronchoalveolar Lavage fluid specimens. J Mol Diagn 22(12):1482\u20131493","journal-title":"J Mol Diagn"},{"issue":"7","key":"4964_CR38","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1016\/j.jiac.2022.04.009","volume":"28","author":"Y Sato","year":"2022","unstructured":"Sato Y, Nirasawa S, Saeki M et al (2022) Comparative study of rapid antigen testing and two nucleic acid amplification tests for influenza virus detection. J Infect Chemother 28(7):1033\u20131036","journal-title":"J Infect Chemother"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-024-04964-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-024-04964-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-024-04964-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,30]],"date-time":"2024-11-30T09:04:40Z","timestamp":1732957480000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-024-04964-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,11]]},"references-count":38,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["4964"],"URL":"https:\/\/doi.org\/10.1007\/s10096-024-04964-y","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"type":"print","value":"0934-9723"},{"type":"electronic","value":"1435-4373"}],"subject":[],"published":{"date-parts":[[2024,10,11]]},"assertion":[{"value":"11 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 October 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 October 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}