{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:56:35Z","timestamp":1792673795201,"version":"4.5.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T00:00:00Z","timestamp":1731888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T00:00:00Z","timestamp":1731888000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1007\/s10096-024-04993-7","type":"journal-article","created":{"date-parts":[[2024,11,17]],"date-time":"2024-11-17T19:51:55Z","timestamp":1731873115000},"page":"251-262","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["High diversity of strain clonality and metallo-\u03b2-lactamases genes among carbapenem-resistant Enterobacterales in Taiwan"],"prefix":"10.1007","volume":"44","author":[{"given":"Jia-Arng","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao-Wen","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin-Hei","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tai-fen","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Hsing","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Tsung","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Ren","family":"Hsueh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,18]]},"reference":[{"key":"4993_CR1","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/S0140-6736(21)02724-0","volume":"399","author":"CJL Murray","year":"2022","unstructured":"Murray CJL, Ikuta KS, Sharara F et al (2022) Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet 399:629\u2013655. https:\/\/doi.org\/10.1016\/S0140-6736(21)02724-0","journal-title":"Lancet"},{"issue":"3","key":"4993_CR2","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/S1473-3099(17)30753-3","volume":"18","author":"E Tacconelli","year":"2018","unstructured":"Tacconelli E, Carrara E, Savoldi A et al (2018) Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis. Lancet Infect Dis 18(3):318\u2013327. https:\/\/doi.org\/10.1016\/S1473-3099(17)30753-3","journal-title":"Lancet Infect Dis"},{"issue":"5","key":"4993_CR3","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1038\/s41579-019-0293-3","volume":"18","author":"C Ardal","year":"2020","unstructured":"Ardal C, Balasegaram M, Laxminarayan R et al (2020) Antibiotic development - economic, regulatory and societal challenges. Nat Rev Microbiol 18(5):267\u2013274. https:\/\/doi.org\/10.1038\/s41579-019-0293-3","journal-title":"Nat Rev Microbiol"},{"issue":"1","key":"4993_CR4","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1128\/CMR.00115-20","volume":"34","author":"D Yahav","year":"2020","unstructured":"Yahav D, Giske CG, Gr\u0101matniece A et al (2020) New \u03b2-lactam\u2013\u03b2-lactamase inhibitor combinations. Clin Microbiol Rev 34(1):10\u20131128. https:\/\/doi.org\/10.1128\/CMR.00115-20","journal-title":"Clin Microbiol Rev"},{"issue":"5","key":"4993_CR5","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1016\/j.mib.2011.07.026","volume":"14","author":"K Coleman","year":"2011","unstructured":"Coleman K (2011) Diazabicyclooctanes (DBOs): a potent new class of non-beta-lactam beta-lactamase inhibitors. Curr Opin Microbiol 14(5):550\u2013555. https:\/\/doi.org\/10.1016\/j.mib.2011.07.026","journal-title":"Curr Opin Microbiol"},{"issue":"10","key":"4993_CR6","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1128\/AAC.00397-20","volume":"64","author":"SE Boyd","year":"2020","unstructured":"Boyd SE, Livermore DM, Hooper DC et al (2020) Metallo-beta-lactamases: structure, function, epidemiology, treatment options, and the development pipeline. Antimicrob Agents Chemother 64(10):10\u20131128. https:\/\/doi.org\/10.1128\/AAC.00397-20","journal-title":"Antimicrob Agents Chemother"},{"issue":"4","key":"4993_CR7","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1093\/jac\/dkad049","volume":"78","author":"WW Nichols","year":"2023","unstructured":"Nichols WW, Bradford PA, Stone GG (2023) The primary pharmacology of ceftazidime\/avibactam: microbiology from clinical studies, and development of resistance during treatment. J Antimicrob Chemother 78(4):871\u2013892. https:\/\/doi.org\/10.1093\/jac\/dkad049","journal-title":"J Antimicrob Chemother"},{"issue":"9","key":"4993_CR8","doi-asserted-by":"publisher","first-page":"2321","DOI":"10.1093\/jac\/dkac171","volume":"77","author":"WW Nichols","year":"2022","unstructured":"Nichols WW, Lahiri SD, Bradford PA et al (2022) The primary pharmacology of ceftazidime\/avibactam: resistance in vitro translational biology. J Antimicrob Chemother 77(9):2321\u20132340. https:\/\/doi.org\/10.1093\/jac\/dkac171","journal-title":"J Antimicrob Chemother"},{"key":"4993_CR9","doi-asserted-by":"publisher","first-page":"1983","DOI":"10.2147\/IDR.S175679","volume":"11","author":"SS Jean","year":"2018","unstructured":"Jean SS, Lu MC, Shi ZY et al (2018) In vitro activity of ceftazidime-avibactam, ceftolozane-tazobactam, and other comparable agents against clinically important Gram-negative bacilli: results from the 2017 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). Infect Drug Resist 11:1983\u20131992. https:\/\/doi.org\/10.2147\/IDR.S175679","journal-title":"Infect Drug Resist"},{"key":"4993_CR10","doi-asserted-by":"publisher","first-page":"545","DOI":"10.2147\/IDR.S193638","volume":"12","author":"CH Liao","year":"2019","unstructured":"Liao CH, Lee NY, Tang HJ et al (2019) Antimicrobial activities of ceftazidime-avibactam, ceftolozane-tazobactam, and other agents against Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa isolated from intensive care units in Taiwan: results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan in 2016. Infect Drug Resist 12:545\u2013552. https:\/\/doi.org\/10.2147\/IDR.S193638","journal-title":"Infect Drug Resist"},{"key":"4993_CR11","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/j.jgar.2021.06.016","volume":"26","author":"YT Huang","year":"2021","unstructured":"Huang YT, Kuo YW, Teng LJ et al (2021) (2021) Comparison of Etest and broth microdilution for evaluating the susceptibility of Staphylococcus aureus and Streptococcus pneumoniae to ceftaroline and of carbapenem-resistant Enterobacterales and Pseudomonas aeruginosa to ceftazidime\/avibactam. J Glob Antimicrob Resist 26:301\u2013307. https:\/\/doi.org\/10.1016\/j.jgar.2021.06.016","journal-title":"J Glob Antimicrob Resist"},{"issue":"3","key":"4993_CR12","doi-asserted-by":"publisher","first-page":"106377","DOI":"10.1016\/j.ijantimicag.2021.106377","volume":"58","author":"YL Lee","year":"2021","unstructured":"Lee YL, Ko WC, Lee WS et al (2021) In-vitro activity of cefiderocol, cefepime\/zidebactam, cefepime\/enmetazobactam, omadacycline, eravacycline and other comparative agents against carbapenem-nonsusceptible Enterobacterales: Results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) in 2017\u20132020. Int J Antimicrob Agents 58(3):106377. https:\/\/doi.org\/10.1016\/j.ijantimicag.2021.106377","journal-title":"Int J Antimicrob Agents"},{"key":"4993_CR13","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1016\/j.jgar.2021.04.001","volume":"25","author":"S Di Bella","year":"2021","unstructured":"Di Bella S, Giacobbe DR, Maraolo AE et al (2021) Resistance to ceftazidime\/avibactam in infections and colonisations by KPC-producing Enterobacterales: a systematic review of observational clinical studies. J Glob Antimicrob Resist 25:268\u2013281. https:\/\/doi.org\/10.1016\/j.jgar.2021.04.001","journal-title":"J Glob Antimicrob Resist"},{"issue":"1","key":"4993_CR14","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.jinf.2022.10.003","volume":"86","author":"JA Lee","year":"2023","unstructured":"Lee JA, Du SH, Lee TF et al (2023) Rapid emergence of ceftazidime-avibactam resistance among carbapenem-resistant Enterobacterales in a tertiary-care hospital in Taiwan. J Infect 86(1):66\u2013117. https:\/\/doi.org\/10.1016\/j.jinf.2022.10.003","journal-title":"J Infect"},{"issue":"2","key":"4993_CR15","doi-asserted-by":"publisher","first-page":"e00115","DOI":"10.1128\/CMR.00115-18","volume":"32","author":"W Wu","year":"2019","unstructured":"Wu W, Feng Y, Tang G et al (2019) NDM metallo-\u03b2-lactamases and their bacterial producers in health care settings. Clin Microbiol Rev 32(2):e00115-e118. https:\/\/doi.org\/10.1128\/CMR.00115-18","journal-title":"Clin Microbiol Rev"},{"issue":"4","key":"4993_CR16","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1093\/cid\/ciad288","volume":"77","author":"AE Boutzoukas","year":"2023","unstructured":"Boutzoukas AE, Komarow L, Chen L et al (2023) International epidemiology of carbapenemase-producing Escherichia coli. Clin Infect Dis 77(4):499\u2013509. https:\/\/doi.org\/10.1093\/cid\/ciad288","journal-title":"Clin Infect Dis"},{"issue":"12","key":"4993_CR17","doi-asserted-by":"publisher","first-page":"2059","DOI":"10.1093\/cid\/ciad100","volume":"76","author":"M Falcone","year":"2023","unstructured":"Falcone M, Tiseo G, Carbonara S et al (2023) Mortality attributable to bloodstream infections caused by different carbapenem-resistant gram-negative Bacilli: results from a nationwide study in Italy (ALARICO Network). Clin Infect Dis 76(12):2059\u20132069. https:\/\/doi.org\/10.1093\/cid\/ciad100","journal-title":"Clin Infect Dis"},{"key":"4993_CR18","unstructured":"CLSI. Performance standards for antimicrobial susceptibility testing. 33rd ed Approved standard, CLSI publication M100-S33 (2020). Clinical and Laboratory Standards Institute, Wayne, PA"},{"issue":"1","key":"4993_CR19","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1128\/AAC.48.1.15-22.2004","volume":"48","author":"L Poirel","year":"2004","unstructured":"Poirel L, Heritier C, Tolun V et al (2004) Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae. Antimicrob Agents Chemother 48(1):15\u201322. https:\/\/doi.org\/10.1128\/AAC.48.1.15-22.2004","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"4993_CR20","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.diagmicrobio.2010.12.002","volume":"70","author":"L Poirel","year":"2011","unstructured":"Poirel L, Walsh TR, Cuvillier V et al (2011) Multiplex PCR for detection of acquired carbapenemase genes. Diagn Microbiol Infect Dis 70(1):119\u2013123. https:\/\/doi.org\/10.1016\/j.diagmicrobio.2010.12.002","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"4","key":"4993_CR21","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1016\/j.jmii.2020.04.006","volume":"54","author":"CH Wang","year":"2021","unstructured":"Wang CH, Ma L, Huang LY et al (2021) Molecular epidemiology and resistance patterns of blaOXA-48 Klebsiella pneumoniae and Escherichia coli: A nationwide multicenter study in Taiwan. J Microbiol Immunol Infect 54(4):665\u2013672. https:\/\/doi.org\/10.1016\/j.jmii.2020.04.006","journal-title":"J Microbiol Immunol Infect"},{"issue":"2","key":"4993_CR22","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.diagmicrobio.2007.01.009","volume":"59","author":"YT Huang","year":"2007","unstructured":"Huang YT, Chang SC, Lauderdale TL et al (2007) Molecular epidemiology of carbapenem-resistant Pseudomonas aeruginosa carrying metallo-\u03b2-lactamase genes in Taiwan. Diagn Microbiol Infect Dis 59(2):211\u2013216. https:\/\/doi.org\/10.1016\/j.diagmicrobio.2007.01.009","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"2","key":"4993_CR23","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1093\/jac\/dkl239","volume":"58","author":"AP Zavascki","year":"2006","unstructured":"Zavascki AP, Barth AL, Goncalves AL et al (2006) The influence of metallo-beta-lactamase production on mortality in nosocomial Pseudomonas aeruginosa infections. J Antimicrob Chemother 58(2):387\u2013392. https:\/\/doi.org\/10.1093\/jac\/dkl239","journal-title":"J Antimicrob Chemother"},{"issue":"3","key":"4993_CR24","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1128\/AAC.02091-17","volume":"62","author":"K Aoki","year":"2018","unstructured":"Aoki K, Harada S, Yahara K et al (2018) Molecular characterization of IMP-1-producing Enterobacter cloacae complex isolates in Tokyo. Antimicrob Agents Chemother 62(3):10\u20131128. https:\/\/doi.org\/10.1128\/AAC.02091-17","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"4993_CR25","doi-asserted-by":"publisher","first-page":"106837","DOI":"10.1016\/j.ijantimicag.2023.106837","volume":"62","author":"K Gartzonika","year":"2023","unstructured":"Gartzonika K, Politi L, Mavroidi A et al (2023) High prevalence of clonally related ST182 NDM-1-producing Enterobacter cloacae complex clinical isolates in Greece. Int J Antimicrob Agents 62(1):106837. https:\/\/doi.org\/10.1016\/j.ijantimicag.2023.106837","journal-title":"Int J Antimicrob Agents"},{"issue":"5","key":"4993_CR26","doi-asserted-by":"publisher","first-page":"878","DOI":"10.3201\/eid2305.162034","volume":"23","author":"BM Wilson","year":"2017","unstructured":"Wilson BM, El Chakhtoura NG, Patel S et al (2017) Carbapenem-resistant Enterobacter cloacae in patients from the US Veterans Health Administration, 2006\u20132015. Emerg Infect Dis 23(5):878. https:\/\/doi.org\/10.3201\/eid2305.162034","journal-title":"Emerg Infect Dis"},{"key":"4993_CR27","doi-asserted-by":"publisher","first-page":"1127948","DOI":"10.3389\/fmicb.2023.1127948","volume":"14","author":"M Han","year":"2023","unstructured":"Han M, Liu C, Xie H et al (2023) Genomic and clinical characteristics of carbapenem-resistant Enterobacter cloacae complex isolates collected in a Chinese tertiary hospital during 2013\u20132021. Front Microbiol 14:1127948. https:\/\/doi.org\/10.3389\/fmicb.2023.1127948","journal-title":"Front Microbiol"},{"issue":"4","key":"4993_CR28","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1007\/s10096-022-04408-5","volume":"41","author":"G Bianco","year":"2022","unstructured":"Bianco G, Boattini M, Comini S et al (2022) Occurrence of multi-carbapenemases producers among carbapenemase-producing Enterobacterales and in vitro activity of combinations including cefiderocol, ceftazidime-avibactam, meropenem-vaborbactam, and aztreonam in the COVID-19 era. Eur J Clin Microbiol Infect Dis 41(4):573\u2013580. https:\/\/doi.org\/10.1007\/s10096-022-04408-5","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"4","key":"4993_CR29","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/j.ijantimicag.2014.12.013","volume":"45","author":"F Al-Marzooq","year":"2015","unstructured":"Al-Marzooq F, Ngeow YF, Tay ST (2015) Emergence of Klebsiella pneumoniae producing dual carbapenemases (NDM-1 and OXA-232) and 16S rRNA methylase (armA) isolated from a Malaysian patient returning from India. Int J Antimicrob Agents 45(4):445\u2013446. https:\/\/doi.org\/10.1016\/j.ijantimicag.2014.12.013","journal-title":"Int J Antimicrob Agents"},{"issue":"5","key":"4993_CR30","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.1093\/jac\/dkx012","volume":"72","author":"J Findlay","year":"2017","unstructured":"Findlay J, Hopkins KL, Loy R et al (2017) OXA-48-like carbapenemases in the UK: an analysis of isolates and cases from 2007 to 2014. J Antimicrob Chemother 72(5):1340\u20131349. https:\/\/doi.org\/10.1093\/jac\/dkx012","journal-title":"J Antimicrob Chemother"},{"issue":"6","key":"4993_CR31","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1016\/j.jmii.2021.07.007","volume":"55","author":"YC Chen","year":"2022","unstructured":"Chen YC, Chen WY, Hsu WY et al (2022) Distribution of beta-lactamases and emergence of carbapenemases co-occurring Enterobacterales isolates with high-level antibiotic resistance identified from patients with intra-abdominal infection in the Asia-Pacific region, 2015\u20132018. J Microbiol Immunol Infect 55(6):1263\u20131272. https:\/\/doi.org\/10.1016\/j.jmii.2021.07.007","journal-title":"J Microbiol Immunol Infect"},{"key":"4993_CR32","doi-asserted-by":"publisher","unstructured":"Takeuchi D, Kerdsin A, Akeda Y et al (2022) Nationwide surveillance in Thailand revealed genotype-dependent dissemination of carbapenem-resistant Enterobacterales. Microb Genom 8(4) https:\/\/doi.org\/10.1099\/mgen.0.000797","DOI":"10.1099\/mgen.0.000797"},{"key":"4993_CR33","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.jhin.2022.09.014","volume":"131","author":"Y Huang","year":"2023","unstructured":"Huang Y, Li J, Wang Q et al (2023) Detection of carbapenem-resistant hypervirulent Klebsiella pneumoniae ST11-K64 co-producing NDM-1 and KPC-2 in a tertiary hospital in Wuhan. J Hosp Infect 131:70\u201380. https:\/\/doi.org\/10.1016\/j.jhin.2022.09.014","journal-title":"J Hosp Infect"},{"issue":"12","key":"4993_CR34","doi-asserted-by":"publisher","first-page":"2066","DOI":"10.1093\/cid\/ciac354","volume":"75","author":"MJ Satlin","year":"2022","unstructured":"Satlin MJ, Chen L, Gomez-Simmonds A et al (2022) Impact of a rapid molecular test for Klebsiella pneumoniae carbapenemase and ceftazidime-avibactam use on outcomes after bacteremia caused by carbapenem-resistant Enterobacterales. Clin Infect Dis 75(12):2066\u20132075. https:\/\/doi.org\/10.1093\/cid\/ciac354","journal-title":"Clin Infect Dis"},{"issue":"3","key":"4993_CR35","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.jmii.2022.02.001","volume":"55","author":"CL Sy","year":"2022","unstructured":"Sy CL, Chen PY, Cheng CW et al (2022) Recommendations and guidelines for the treatment of infections due to multidrug resistant organisms. J Microbiol Immunol Infect 55(3):359\u2013386. https:\/\/doi.org\/10.1016\/j.jmii.2022.02.001","journal-title":"J Microbiol Immunol Infect"},{"issue":"11","key":"4993_CR36","doi-asserted-by":"publisher","first-page":"1871","DOI":"10.1093\/cid\/ciaa586","volume":"72","author":"M Falcone","year":"2021","unstructured":"Falcone M, Daikos GL, Tiseo G et al (2021) Efficacy of ceftazidime-avibactam plus aztreonam in patients with bloodstream infections caused by metallo-\u03b2-lactamase\u2013producing Enterobacterales. Clin Infect Dis 72(11):1871\u20131878. https:\/\/doi.org\/10.1093\/cid\/ciaa586","journal-title":"Clin Infect Dis"},{"key":"4993_CR37","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1007\/s10096-024-04841-8","volume":"43","author":"W Li","year":"2024","unstructured":"Li W, Zhang J, Fu Y et al (2024) In vitro and in vivo activity of ceftazidime\/avibactam and aztreonam alone or in combination against mcr-9, serine- and metallo-\u03b2-lactamases\u2013co-producing carbapenem-resistant Enterobacter cloacae complex. Eur J Clin Microbiol Infect Dis 43:1309\u20131318. https:\/\/doi.org\/10.1007\/s10096-024-04841-8","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"12","key":"4993_CR38","doi-asserted-by":"publisher","first-page":"e0279715","DOI":"10.1371\/journal.pone.0279715","volume":"17","author":"FP Dwomoh","year":"2022","unstructured":"Dwomoh FP, Kotey FC, Dayie NT et al (2022) Phenotypic and genotypic detection of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in Accra. Ghana PLoS One 17(12):e0279715. https:\/\/doi.org\/10.1371\/journal.pone.0279715","journal-title":"Ghana PLoS One"},{"issue":"1","key":"4993_CR39","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s12941-023-00579-x","volume":"22","author":"SM Brecher","year":"2023","unstructured":"Brecher SM, Tickler IA, Tenover FC (2023) Phenotypic and genotypic discrepancies for carbapenemase-producing Citrobacter freundii in multiple isolates from a single patient. Ann Clin Microbiol Antimicrob 22(1):24. https:\/\/doi.org\/10.1186\/s12941-023-00579-x","journal-title":"Ann Clin Microbiol Antimicrob"},{"key":"4993_CR40","doi-asserted-by":"publisher","first-page":"e83107","DOI":"10.7554\/eLife.83107","volume":"12","author":"NC Rosas","year":"2023","unstructured":"Rosas NC, Wilksch J, Barber J et al (2023) The evolutionary mechanism of non-carbapenemase carbapenem-resistant phenotypes in Klebsiella spp. Elife 12:e83107. https:\/\/doi.org\/10.7554\/eLife.83107","journal-title":"Elife"},{"key":"4993_CR41","doi-asserted-by":"publisher","first-page":"127249","DOI":"10.1016\/j.micres.2022.127249","volume":"266","author":"J Ma","year":"2023","unstructured":"Ma J, Song X, Li M et al (2023) Global spread of carbapenem-resistant Enterobacteriaceae: Epidemiological features, resistance mechanisms, detection and therapy. Microbiol Res 266:127249. https:\/\/doi.org\/10.1016\/j.micres.2022.127249","journal-title":"Microbiol Res"},{"key":"4993_CR42","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.jgar.2019.12.009","volume":"22","author":"Y Wang","year":"2020","unstructured":"Wang Y, Wang J, Wang R et al (2020) Resistance to ceftazidime\u2013avibactam and underlying mechanisms. Journal of global antimicrobial resistance 22:18\u201327. https:\/\/doi.org\/10.1016\/j.jgar.2019.12.009","journal-title":"Journal of global antimicrobial resistance"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-024-04993-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-024-04993-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-024-04993-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T09:47:50Z","timestamp":1737539270000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-024-04993-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,18]]},"references-count":42,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["4993"],"URL":"https:\/\/doi.org\/10.1007\/s10096-024-04993-7","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,18]]},"assertion":[{"value":"24 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The present study was performed in line with the principles of the Declaration of Helsinki. The institutional review board of the National Taiwan University Hospital approved the study (IRB number: 202201020RINC).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Because of the retrospective design of the study, the ethics committee waived the requirement of informed consent to participate.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}