{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:55:01Z","timestamp":1792036501837,"version":"4.4.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T00:00:00Z","timestamp":1734480000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T00:00:00Z","timestamp":1734480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1007\/s10096-024-05012-5","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T03:14:25Z","timestamp":1734491665000},"page":"427-436","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Risk of mortality in Fusobacterium species bloodstream infection from a large Australian cohort"],"prefix":"10.1007","volume":"44","author":[{"given":"Adam G.","family":"Stewart","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicity","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick N. A.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.","family":"Paterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin B.","family":"Laupland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,18]]},"reference":[{"issue":"4","key":"5012_CR1","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1128\/CMR.00011-07","volume":"20","author":"T Riordan","year":"2007","unstructured":"Riordan T (2007) Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre\u2019s syndrome. Clin Microbiol Rev 20(4):622\u2013659","journal-title":"Clin Microbiol Rev"},{"issue":"2","key":"5012_CR2","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/0002-9343(83)91196-8","volume":"75","author":"S Henry","year":"1983","unstructured":"Henry S, DeMaria A Jr., McCabe WR (1983) Bacteremia due to Fusobacterium species. Am J Med 75(2):225\u2013231","journal-title":"Am J Med"},{"issue":"Suppl 1","key":"5012_CR3","doi-asserted-by":"publisher","first-page":"S22","DOI":"10.1086\/341916","volume":"35","author":"DM Citron","year":"2002","unstructured":"Citron DM (2002) Update on the taxonomy and clinical aspects of the genus fusobacterium. Clin Infect Dis 35(Suppl 1):S22\u2013S27","journal-title":"Clin Infect Dis"},{"issue":"2","key":"5012_CR4","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1128\/jcm.32.2.384-387.1994","volume":"32","author":"SS Jang","year":"1994","unstructured":"Jang SS, Hirsh DC (1994) Characterization, distribution, and microbiological associations of Fusobacterium spp. in clinical specimens of animal origin. J Clin Microbiol 32(2):384\u2013387","journal-title":"J Clin Microbiol"},{"issue":"4","key":"5012_CR5","doi-asserted-by":"publisher","first-page":"241","DOI":"10.7326\/M14-1305","volume":"162","author":"RM Centor","year":"2015","unstructured":"Centor RM et al (2015) The clinical presentation of Fusobacterium-positive and streptococcal-positive pharyngitis in a university health clinic: a cross-sectional study. Ann Intern Med 162(4):241\u2013247","journal-title":"Ann Intern Med"},{"issue":"3","key":"5012_CR6","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1099\/0022-1317-51-3-269","volume":"51","author":"JS Brazier","year":"2002","unstructured":"Brazier JS et al (2002) Fusobacterium necrophorum infections in England and Wales 1990\u20132000. J Med Microbiol 51(3):269\u2013272","journal-title":"J Med Microbiol"},{"issue":"4","key":"5012_CR7","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.anaerobe.2005.11.003","volume":"12","author":"JS Brazier","year":"2006","unstructured":"Brazier JS (2006) Human infections with Fusobacterium necrophorum. Anaerobe 12(4):165\u2013172","journal-title":"Anaerobe"},{"key":"5012_CR8","doi-asserted-by":"crossref","unstructured":"Fujiwara N et al (2020) Involvement of Fusobacterium species in oral Cancer progression: a Literature Review Including other types of Cancer. Int J Mol Sci, 21(17)","DOI":"10.3390\/ijms21176207"},{"issue":"9","key":"5012_CR9","doi-asserted-by":"publisher","first-page":"7209","DOI":"10.18632\/oncotarget.3109","volume":"6","author":"K Mitsuhashi","year":"2015","unstructured":"Mitsuhashi K et al (2015) Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis. Oncotarget 6(9):7209\u20137220","journal-title":"Oncotarget"},{"issue":"1","key":"5012_CR10","doi-asserted-by":"publisher","first-page":"e53653","DOI":"10.1371\/journal.pone.0053653","volume":"8","author":"AN McCoy","year":"2013","unstructured":"McCoy AN et al (2013) Fusobacterium is associated with colorectal adenomas. PLoS ONE 8(1):e53653","journal-title":"PLoS ONE"},{"issue":"1","key":"5012_CR11","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1136\/gut.2009.191320","volume":"60","author":"A Swidsinski","year":"2011","unstructured":"Swidsinski A et al (2011) Acute appendicitis is characterised by local invasion with Fusobacterium nucleatum\/necrophorum. Gut 60(1):34\u201340","journal-title":"Gut"},{"issue":"9","key":"5012_CR12","doi-asserted-by":"publisher","first-page":"1971","DOI":"10.1002\/ibd.21606","volume":"17","author":"J Strauss","year":"2011","unstructured":"Strauss J et al (2011) Invasive potential of gut mucosa-derived Fusobacterium nucleatum positively correlates with IBD status of the host. Inflamm Bowel Dis 17(9):1971\u20131978","journal-title":"Inflamm Bowel Dis"},{"issue":"7","key":"5012_CR13","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1086\/653207","volume":"31","author":"J Leal","year":"2010","unstructured":"Leal J et al (2010) Development of a novel electronic surveillance system for monitoring of bloodstream infections. Infect Control Hosp Epidemiol 31(7):740\u2013747","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"10","key":"5012_CR14","doi-asserted-by":"publisher","first-page":"791","DOI":"10.7326\/0003-4819-137-10-200211190-00007","volume":"137","author":"ND Friedman","year":"2002","unstructured":"Friedman ND et al (2002) Health care\u2013associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections. Ann Intern Med 137(10):791\u2013797","journal-title":"Ann Intern Med"},{"issue":"5","key":"5012_CR15","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","volume":"40","author":"ME Charlson","year":"1987","unstructured":"Charlson ME et al (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40(5):373\u2013383","journal-title":"J Chronic Dis"},{"issue":"11","key":"5012_CR16","doi-asserted-by":"publisher","first-page":"1130","DOI":"10.1097\/01.mlr.0000182534.19832.83","volume":"43","author":"H Quan","year":"2005","unstructured":"Quan H et al (2005) Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care 43(11):1130\u20131139","journal-title":"Med Care"},{"key":"5012_CR17","unstructured":"Queensland Population Projects (2002) to 2026. 22 September 2021]; https:\/\/public.tableau.com\/views\/HHSpopulationprojections"},{"issue":"8","key":"5012_CR18","doi-asserted-by":"publisher","first-page":"910e1","DOI":"10.1016\/j.cmi.2017.12.021","volume":"24","author":"KB Laupland","year":"2018","unstructured":"Laupland KB et al (2018) Culturing rate and the surveillance of bloodstream infections: a population-based assessment. Clin Microbiol Infect 24(8):910e1\u2013910e4","journal-title":"Clin Microbiol Infect"},{"key":"5012_CR19","doi-asserted-by":"publisher","first-page":"102165","DOI":"10.1016\/j.anaerobe.2020.102165","volume":"62","author":"AM Almohaya","year":"2020","unstructured":"Almohaya AM et al (2020) Fusobacterium bloodstream infections: a literature review and hospital-based case series. Anaerobe 62:102165","journal-title":"Anaerobe"},{"issue":"4","key":"5012_CR20","doi-asserted-by":"publisher","first-page":"e30","DOI":"10.4110\/in.2020.20.e30","volume":"20","author":"M King","year":"2020","unstructured":"King M et al (2020) The link between Fusobacteria and Colon cancer: a fulminant example and review of the evidence. Immune Netw 20(4):e30","journal-title":"Immune Netw"},{"issue":"1","key":"5012_CR21","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1111\/prd.12426","volume":"89","author":"T Alon-Maimon","year":"2022","unstructured":"Alon-Maimon T, Mandelboim O, Bachrach G (2022) Fusobacterium nucleatum and cancer. Periodontol 2000 89(1):166\u2013180","journal-title":"Periodontol 2000"},{"issue":"8","key":"5012_CR22","doi-asserted-by":"publisher","first-page":"4293","DOI":"10.1128\/JCM.43.8.4293-4295.2005","volume":"43","author":"MC Legaria","year":"2005","unstructured":"Legaria MC et al (2005) Clindamycin-resistant Fusobacterium varium bacteremia and decubitus ulcer infection. J Clin Microbiol 43(8):4293\u20134295","journal-title":"J Clin Microbiol"},{"key":"5012_CR23","doi-asserted-by":"publisher","first-page":"102168","DOI":"10.1016\/j.anaerobe.2020.102168","volume":"62","author":"MM Vidaurrazaga","year":"2020","unstructured":"Vidaurrazaga MM, McKinley GF, Camins BC (2020) Postpartum Fusobacterium gonidiaformans bacteremia. Anaerobe 62:102168","journal-title":"Anaerobe"},{"issue":"4","key":"5012_CR24","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1515\/jccm-2017-0029","volume":"3","author":"R Garcia-Carretero","year":"2017","unstructured":"Garcia-Carretero R et al (2017) Clinical features and outcomes of Fusobacterium species infections in a ten-year follow-up. J Crit Care Med (Targu Mures) 3(4):141\u2013147","journal-title":"J Crit Care Med (Targu Mures)"},{"issue":"2","key":"5012_CR25","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1007\/s15010-013-0564-2","volume":"42","author":"E Pett","year":"2014","unstructured":"Pett E, Saeed K, Dryden M (2014) Fusobacterium species infections: clinical spectrum and outcomes at a district general hospital. Infection 42(2):363\u2013370","journal-title":"Infection"},{"issue":"2","key":"5012_CR26","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.diagmicrobio.2010.12.017","volume":"70","author":"CC Yang","year":"2011","unstructured":"Yang CC et al (2011) Characteristics and outcomes of Fusobacterium nucleatum bacteremia\u2013a 6-year experience at a tertiary care hospital in northern Taiwan. Diagn Microbiol Infect Dis 70(2):167\u2013174","journal-title":"Diagn Microbiol Infect Dis"},{"key":"5012_CR27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.anaerobe.2016.02.001","volume":"39","author":"E Yusuf","year":"2016","unstructured":"Yusuf E, Wybo I, Pi\u00e9rard D (2016) Case series of patients with Fusobacterium nucleatum bacteremia with emphasis on the presence of cancer. Anaerobe 39:1\u20133","journal-title":"Anaerobe"},{"issue":"Suppl 2","key":"5012_CR28","doi-asserted-by":"publisher","first-page":"S181","DOI":"10.1086\/516181","volume":"25","author":"AM Bourgault","year":"1997","unstructured":"Bourgault AM et al (1997) Fusobacterium bacteremia: clinical experience with 40 cases. Clin Infect Dis 25(Suppl 2):S181\u2013S183","journal-title":"Clin Infect Dis"},{"key":"5012_CR29","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1186\/1471-2334-13-264","volume":"13","author":"K Afra","year":"2013","unstructured":"Afra K et al (2013) Incidence, risk factors, and outcomes of Fusobacterium species bacteremia. BMC Infect Dis 13:264","journal-title":"BMC Infect Dis"},{"issue":"4","key":"5012_CR30","first-page":"336","volume":"42","author":"CP Su","year":"2009","unstructured":"Su CP et al (2009) Fusobacterium bacteremia: clinical significance and outcomes. J Microbiol Immunol Infect 42(4):336\u2013342","journal-title":"J Microbiol Immunol Infect"},{"issue":"11","key":"5012_CR31","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1046\/j.1469-0691.2003.00717.x","volume":"9","author":"A Candoni","year":"2003","unstructured":"Candoni A et al (2003) Fusobacterium nucleatum: a rare cause of bacteremia in neutropenic patients with leukemia and lymphoma. Clin Microbiol Infect 9(11):1112\u20131115","journal-title":"Clin Microbiol Infect"},{"issue":"5","key":"5012_CR32","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1007\/s00520-003-0452-x","volume":"11","author":"P Fanourgiakis","year":"2003","unstructured":"Fanourgiakis P et al (2003) Febrile neutropenia and Fusobacterium bacteremia: clinical experience with 13 cases. Support Care Cancer 11(5):332\u2013335","journal-title":"Support Care Cancer"},{"key":"5012_CR33","doi-asserted-by":"publisher","first-page":"102099","DOI":"10.1016\/j.anaerobe.2019.102099","volume":"61","author":"J Seibel","year":"2020","unstructured":"Seibel J et al (2020) Fusobacterium nucleatum bacteremia with pneumopathy in a patient receiving eculizumab: a case report. Anaerobe 61:102099","journal-title":"Anaerobe"},{"issue":"3","key":"5012_CR34","doi-asserted-by":"publisher","first-page":"975","DOI":"10.3201\/eid2703.202284","volume":"27","author":"L Wolff","year":"2021","unstructured":"Wolff L et al (2021) COVID-19-Associated Fusobacterium nucleatum Bacteremia, Belgium. Emerg Infect Dis 27(3):975\u2013977","journal-title":"Emerg Infect Dis"},{"issue":"4","key":"5012_CR35","doi-asserted-by":"publisher","first-page":"1238","DOI":"10.1128\/AAC.45.4.1238-1243.2001","volume":"45","author":"KE Aldridge","year":"2001","unstructured":"Aldridge KE et al (2001) Multicenter survey of the changing in vitro antimicrobial susceptibilities of clinical isolates of Bacteroides fragilis group, Prevotella, Fusobacterium, Porphyromonas, and Peptostreptococcus species. Antimicrob Agents Chemother 45(4):1238\u20131243","journal-title":"Antimicrob Agents Chemother"},{"issue":"5","key":"5012_CR36","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1128\/AAC.43.5.1270","volume":"43","author":"E K\u00f6n\u00f6nen","year":"1999","unstructured":"K\u00f6n\u00f6nen E et al (1999) beta-lactamase production and antimicrobial susceptibility of oral heterogeneous Fusobacterium nucleatum populations in young children. Antimicrob Agents Chemother 43(5):1270\u20131273","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"5012_CR37","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1093\/jac\/dkg022","volume":"51","author":"S Nyfors","year":"2003","unstructured":"Nyfors S et al (2003) Emergence of penicillin resistance among Fusobacterium nucleatum populations of commensal oral flora during early childhood. J Antimicrob Chemother 51(1):107\u2013112","journal-title":"J Antimicrob Chemother"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-024-05012-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-024-05012-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-024-05012-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T09:47:33Z","timestamp":1737539253000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-024-05012-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,18]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["5012"],"URL":"https:\/\/doi.org\/10.1007\/s10096-024-05012-5","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,18]]},"assertion":[{"value":"16 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The Human Research Ethics Committee (HREC) at Royal Brisbane and Women\u2019s Hospital approved this study and granted a waiver of individual consent (LNR\/2020\/QRBW\/62494).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"DLP has received research grants from Merck, Pfizer, bioMerieux and Shionogi outside of the submitted work. He has also received personal fees from AMR Action Fund, Merck, Pfizer, Shionogi, Spero, Lysovant, The Medicines Company, Entasis, VenatoRx, QPex, bioMerieux and Accelerate and is conducting a study on E. coli vaccination sponsored by Janssen. PNAH has received research grants from Merck, Sharpe and Dohme (MSD), Sandoz and Shionogi Ltd, outside of the submitted work, and has served on advisory boards for OpGen, Merck and Sandoz and received speakers fees from Pfizer, OpGen and Sandoz paid to the University of Queensland. All other authors: none to declare.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}