{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T04:03:56Z","timestamp":1746763436562,"version":"3.40.5"},"reference-count":61,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:00:00Z","timestamp":1740096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:00:00Z","timestamp":1740096000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1007\/s10096-025-05074-z","type":"journal-article","created":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T13:20:42Z","timestamp":1740144042000},"page":"1107-1118","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Trends in incidence of neonatal late-onset sepsis in very low birth weight infants: a 15-year Brazilian single center analysis"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0186-0320","authenticated-orcid":false,"given":"B\u00e1rbara Barros Pereira","family":"Lobo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5292-2320","authenticated-orcid":false,"given":"Jamil Pedro","family":"de Siqueira\u00a0Caldas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,2,21]]},"reference":[{"issue":"2","key":"5074_CR1","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.idc.2016.02.001","volume":"30","author":"RR Watkins","year":"2016","unstructured":"Watkins RR, Bonomo RA (2016) Overview: global and local impact of Antibiotic Resistance. Infect Dis Clin North Am 30(2):313\u2013322. https:\/\/doi.org\/10.1016\/j.idc.2016.02.001","journal-title":"Infect Dis Clin North Am"},{"issue":"10325","key":"5074_CR2","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/S0140-6736(21)02724-0","volume":"399","author":"CJL Murray","year":"2022","unstructured":"Murray CJL, Ikuta KS, Sharara F, Swetschinski L, Robles Aguilar G, Gray A et al (2022) Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet 399(10325):629\u2013655","journal-title":"Lancet"},{"issue":"3","key":"5074_CR3","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1016\/j.clp.2010.06.004","volume":"37","author":"SJ Patel","year":"2010","unstructured":"Patel SJ, Saiman L (2010) Antibiotic Resistance in neonatal intensive care unit pathogens: mechanisms, clinical impact, and Prevention Including Antibiotic Stewardship. Clin Perinatol 37(3):547\u2013563","journal-title":"Clin Perinatol"},{"key":"5074_CR4","doi-asserted-by":"publisher","unstructured":"Cantey JB, Milstone AM (2015) Bloodstream infections: epidemiology and resistance. Clin Perinatol 42(1):1\u201316, vii. https:\/\/doi.org\/10.1016\/j.clp.2014.10.002","DOI":"10.1016\/j.clp.2014.10.002"},{"issue":"4","key":"5074_CR5","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1136\/adc.2010.199653","volume":"96","author":"JW Gray","year":"2011","unstructured":"Gray JW, Patel M (2011) Management of antibiotic-resistant infection in the newborn. Arch Dis Child Educ Pract Ed 96(4):122\u2013127","journal-title":"Arch Dis Child Educ Pract Ed"},{"issue":"1","key":"5074_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/tropej\/fmu079","volume":"61","author":"A Zea-Vera","year":"2015","unstructured":"Zea-Vera A, Ochoa TJ (2015) Challenges in the diagnosis and management of neonatal sepsis. J Trop Pediatr 61(1):1\u201313","journal-title":"J Trop Pediatr"},{"issue":"2","key":"5074_CR7","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/j.pcl.2012.12.003","volume":"60","author":"A Camacho-Gonzalez","year":"2013","unstructured":"Camacho-Gonzalez A, Spearman PW, Stoll BJ (2013) Neonatal infectious diseases. Pediatr Clin North Am 60(2):367\u2013389","journal-title":"Pediatr Clin North Am"},{"issue":"6","key":"5074_CR8","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1097\/PCC.0000000000000157","volume":"15","author":"JL Wynn","year":"2014","unstructured":"Wynn JL, Wong HR, Shanley TP, Bizzarro MJ, Saiman L, Polin RA (2014) Time for a neonatal-specific consensus definition for sepsis. Pediatr Crit Care Med 15(6):523\u2013528","journal-title":"Pediatr Crit Care Med"},{"issue":"2","key":"5074_CR9","first-page":"CD011926","volume":"2","author":"M Pammi","year":"2017","unstructured":"Pammi M, Flores A, Versalovic J, Leeflang MM (2017) Molecular assays for the diagnosis of sepsis in neonates. Cochrane Database Syst Rev 2(2):CD011926","journal-title":"Cochrane Database Syst Rev"},{"issue":"8","key":"5074_CR10","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1097\/INF.0b013e31825691e4","volume":"31","author":"CP Hornik","year":"2012","unstructured":"Hornik CP, Benjamin DK, Becker KC, Benjamin DK, Li J, Clark RH et al (2012) Use of the complete blood cell count in late-onset neonatal sepsis. Pediatr Infect Dis J 31(8):803\u2013807","journal-title":"Pediatr Infect Dis J"},{"key":"5074_CR11","doi-asserted-by":"crossref","unstructured":"Beaumont R, Tang K, Gwee A (2024) The sensitivity and specificity of Procalcitonin in diagnosing bacterial Sepsis in neonates. Hosp Pediatr 14(3)","DOI":"10.1542\/hpeds.2023-007318"},{"issue":"4","key":"5074_CR12","doi-asserted-by":"publisher","first-page":"e973","DOI":"10.1542\/peds.2011-1208","volume":"128","author":"M Pammi","year":"2011","unstructured":"Pammi M, Flores A, Leeflang M, Versalovic J (2011) Molecular assays in the diagnosis of neonatal Sepsis: a systematic review and Meta-analysis. Pediatrics 128(4):e973\u2013985","journal-title":"Pediatrics"},{"key":"5074_CR13","doi-asserted-by":"crossref","unstructured":"Kosmeri C, Giapros V, Serbis A, Baltogianni M (2024) Application of Advanced Molecular methods to study early-onset neonatal Sepsis. Int J Mol Sci 25(4)","DOI":"10.3390\/ijms25042258"},{"issue":"1","key":"5074_CR14","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1007\/s00431-017-3036-3","volume":"177","author":"I Garc\u00eda-Gudi\u00f1o","year":"2018","unstructured":"Garc\u00eda-Gudi\u00f1o I, Yllescas-Medrano E, Maida-Claros R, Soriano-Becerril D, D\u00edaz NF, Garc\u00eda-L\u00f3pez G et al (2018) Microbiological comparison of blood culture and amplification of 16S rDNA methods in combination with DGGE for detection of neonatal sepsis in blood samples. Eur J Pediatr 177(1):85\u201393. https:\/\/doi.org\/10.1007\/s00431-017-3036-3","journal-title":"Eur J Pediatr"},{"issue":"1","key":"5074_CR15","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1038\/s41390-020-0850-5","volume":"88","author":"EJ Molloy","year":"2020","unstructured":"Molloy EJ, Wynn JL, Bliss J, Koenig JM, Keij FM, McGovern M et al (2020) Neonatal sepsis: need for consensus definition, collaboration and core outcomes. Pediatr Res 88(1):2\u20134","journal-title":"Pediatr Res"},{"issue":"4","key":"5074_CR16","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/j.bjid.2018.07.009","volume":"22","author":"ACB Silva","year":"2018","unstructured":"Silva ACB, Anchieta LM, Lopes MFP, Romanelli RMC (2018) Inadequate use of antibiotics and increase in neonatal sepsis caused by resistant bacteria related to health care assistance: a systematic review. Braz J Infect Dis 22(4):328\u2013337","journal-title":"Braz J Infect Dis"},{"issue":"3","key":"5074_CR17","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.jped.2020.06.001","volume":"97","author":"ACB Silva","year":"2021","unstructured":"Silva ACB, Anchieta LM, Rosado V, Ferreira J, Clemente WT, Coelho JS et al (2021) Antimicrobial use for treatment of healthcare-associated infections and bacterial resistance in a reference neonatal unit. J Pediatr (Rio J) 97(3):329\u2013334","journal-title":"J Pediatr (Rio J)"},{"issue":"3","key":"5074_CR18","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1067\/mic.2001.114223","volume":"29","author":"R Calil","year":"2001","unstructured":"Calil R, Marba STM, Von Nowakonski A, Tresoldi AT (2001) Reduction in colonization and nosocomial infection by multiresistant bacteria in a neonatal unit after institution of educational measures and restriction in the use of cephalosporins. Am J Infect Control 29(3):133\u2013138","journal-title":"Am J Infect Control"},{"issue":"3","key":"5074_CR19","doi-asserted-by":"publisher","first-page":"F244","DOI":"10.1136\/archdischild-2016-310905","volume":"102","author":"D Carr","year":"2017","unstructured":"Carr D, Barnes EH, Gordon A, Isaacs D (2017) Effect of antibiotic use on antimicrobial antibiotic resistance and late-onset neonatal infections over 25 years in an Australian tertiary neonatal unit. Arch Dis Child Fetal Neonatal Ed 102(3):F244\u2013F250","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"5","key":"5074_CR20","doi-asserted-by":"publisher","first-page":"F474","DOI":"10.1136\/archdischild-2017-313238","volume":"103","author":"B Cailes","year":"2018","unstructured":"Cailes B, Kortsalioudaki C, Buttery J, Pattnayak S, Greenough A, Matthes J et al (2018) Antimicrobial resistance in UK neonatal units: neonIN infection surveillance network. Arch Dis Child Fetal Neonatal Ed 103(5):F474\u2013478. https:\/\/doi.org\/10.1136\/archdischild-2017-313238","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"5074_CR21","doi-asserted-by":"publisher","DOI":"10.15620\/cdc:82532","volume-title":"Antibiotic resistance threats in the United States, 2019","author":"Centers for Disease Control and Prevention","year":"2019","unstructured":"Centers for Disease Control and Prevention (2019) Antibiotic resistance threats in the United States, 2019. U.S. Department of Health and Human Services, CDC, Atlanta, GA"},{"key":"5074_CR22","unstructured":"Brasil. Ag\u00eancia Nacional de Vigilancia Sanitaria (2021) Preven\u00e7\u00e3o de infec\u00e7\u00f5es por microrganismos multirresistentes em servi\u00e7os de sa\u00fade\u2013 S\u00e9rie. Seguran\u00e7a do Paciente e Qualidade em Servi\u00e7os de Sa\u00fade"},{"issue":"4","key":"5074_CR23","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1016\/j.jped.2020.07.006","volume":"97","author":"JPS Caldas","year":"2021","unstructured":"Caldas JPS, Montera LC, Calil R, Marba STM (2021) Temporal trend in early sepsis in a very low birth weight infants\u2019 cohort: an opportunity for a rational antimicrobial use. J Pediatr (Rio J) 97(4):414\u2013419","journal-title":"J Pediatr (Rio J)"},{"issue":"1","key":"5074_CR24","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.ajic.2024.08.007","volume":"53","author":"IGM Bazan","year":"2025","unstructured":"Bazan IGM, Lobo BBP, Schreiber AZ, Calil R, Marba STM, Caldas JPS (2025) Long-lasting effects of control measures on trends in incidence in neonatal late-onset sepsis due to multiresistant bacteria in a Brazilian neonatal unit. Am J Infect Control 53(1):22\u201329","journal-title":"Am J Infect Control"},{"key":"5074_CR25","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.ijid.2018.04.794","volume":"71","author":"JY Li","year":"2018","unstructured":"Li JY, Chen SQ, Yan YY, Hu YY, Wei J, Wu QP et al (2018) Identification and antimicrobial resistance of pathogens in neonatal septicemia in China-A meta-analysis. Int J Infect Dis 71:89\u201393. https:\/\/doi.org\/10.1016\/j.ijid.2018.04.794","journal-title":"Int J Infect Dis"},{"key":"5074_CR26","doi-asserted-by":"publisher","first-page":"694093","DOI":"10.3389\/fcimb.2021.694093","volume":"11","author":"H Zou","year":"2021","unstructured":"Zou H, Jia X, He X, Su Y, Zhou L, Shen Y et al (2021) Emerging threat of Multidrug resistant pathogens from neonatal Sepsis. Front Cell Infect Microbiol 11:694093. https:\/\/doi.org\/10.3389\/fcimb.2021.694093","journal-title":"Front Cell Infect Microbiol"},{"key":"5074_CR27","doi-asserted-by":"publisher","first-page":"820577","DOI":"10.3389\/fmicb.2022.820577","volume":"13","author":"X Zhang","year":"2022","unstructured":"Zhang X, Li Y, Tao Y, Ding Y, Shao X, Li W (2022) Epidemiology and drug resistance of neonatal bloodstream infection pathogens in East China Children\u2019s Medical Center from 2016 to 2020. Front Microbiol 13:820577","journal-title":"Front Microbiol"},{"issue":"5","key":"5074_CR28","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1080\/14767058.2020.1732342","volume":"35","author":"J Wang","year":"2022","unstructured":"Wang J, Zhang H, Yan J, Zhang T (2022) Literature review on the distribution characteristics and antimicrobial resistance of bacterial pathogens in neonatal sepsis. J Maternal-Fetal Neonatal Med 35(5):861\u2013870","journal-title":"J Maternal-Fetal Neonatal Med"},{"issue":"21","key":"5074_CR29","doi-asserted-by":"publisher","first-page":"3658","DOI":"10.1080\/14767058.2019.1582633","volume":"33","author":"M Mutlu","year":"2020","unstructured":"Mutlu M, Aslan Y, Akt\u00fcrk Acar F, Kader S, Bayramoglu G, Yilmaz G (2020) Changing trend of microbiologic profile and antibiotic susceptibility of the microorganisms isolated in the neonatal nosocomial sepsis: a 14 years analysis. J Matern Fetal Neonatal Med 33(21):3658\u20133665. https:\/\/doi.org\/10.1080\/14767058.2019.1582633","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"4","key":"5074_CR30","doi-asserted-by":"publisher","first-page":"433","DOI":"10.4067\/S0716-10182019000400433","volume":"36","author":"JC Lona-Reyes","year":"2019","unstructured":"Lona-Reyes JC, P\u00e9rez-Ram\u00edrez RO, Rodr\u00edguez-Pati\u00f1o V, Cordero-Zamora A, G\u00f3mez-Ruiz LM, Llamas-Ramos L (2019) Prevalencia De beta-lactamasas de espectro extendido en enterobacterias causantes de sepsis neonatal y factores asociados. Rev Chil Infectol 36(4):433\u2013441","journal-title":"Rev Chil Infectol"},{"issue":"3","key":"5074_CR31","doi-asserted-by":"publisher","first-page":"F293","DOI":"10.1136\/archdischild-2018-315024","volume":"104","author":"D Gkentzi","year":"2019","unstructured":"Gkentzi D, Kortsalioudaki C, Cailes BC, Zaoutis T, Kopsidas J, Tsolia M et al (2019) Epidemiology of infections and antimicrobial use in Greek neonatal units. Arch Dis Child Fetal Neonatal Ed 104(3):F293\u2013297. https:\/\/doi.org\/10.1136\/archdischild-2018-315024","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"7","key":"5074_CR32","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1097\/INF.0b013e31819988bf","volume":"28","author":"FC Lessa","year":"2009","unstructured":"Lessa FC, Edwards JR, Fridkin SK, Tenover FC, Horan TC, Gorwitz RJ (2009) Trends in incidence of late-onset methicillin-resistant Staphylococcus aureus infection in neonatal intensive care units. Pediatr Infect Dis J 28(7):577\u2013581","journal-title":"Pediatr Infect Dis J"},{"issue":"2","key":"5074_CR33","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.jiph.2022.12.017","volume":"16","author":"Z Zahoor","year":"2023","unstructured":"Zahoor Z, Mumtaz A, Farooqi ZUR, Rehman N, Batool N, Noreen Z et al (2023) High prevalence of Panton-Valentine Leucocidin (PVL) toxin carrying MRSA and multidrug resistant gram negative bacteria in late onset neonatal sepsis indicate nosocomial spread in a Pakistani tertiary care hospital. J Infect Public Health 16(2):266\u2013271","journal-title":"J Infect Public Health"},{"issue":"6","key":"5074_CR34","doi-asserted-by":"publisher","first-page":"e0180705","DOI":"10.1371\/journal.pone.0180705","volume":"13","author":"M Jajoo","year":"2018","unstructured":"Jajoo M, Manchanda V, Chaurasia S, Sankar MJ, Gautam H, Agarwal R et al (2018) Alarming rates of antimicrobial resistance and fungal sepsis in outborn neonates in North India. PLoS ONE 13(6):e0180705\u2013e0180705. https:\/\/doi.org\/10.1371\/journal.pone.0180705","journal-title":"PLoS ONE"},{"key":"5074_CR35","doi-asserted-by":"crossref","unstructured":"Ballot DE, Nana T, Sriruttan C, Cooper PA (2012) Bacterial bloodstream infections in neonates in a developing country. ISRN Pediatr 2012:508512","DOI":"10.5402\/2012\/508512"},{"issue":"6","key":"5074_CR36","doi-asserted-by":"publisher","first-page":"e0235391","DOI":"10.1371\/journal.pone.0235391","volume":"15","author":"Y Weldu","year":"2020","unstructured":"Weldu Y, Naizgi M, Hadgu A, Desta AA, Kahsay A, Negash L et al (2020) Neonatal septicemia at intensive care unit, Ayder Comprehensive Specialized Hospital, Tigray, North Ethiopia: bacteriological profile, drug susceptibility pattern, and associated factors. PLoS ONE 15(6):e0235391\u2013e0235391. https:\/\/doi.org\/10.1371\/journal.pone.0235391","journal-title":"PLoS ONE"},{"key":"5074_CR37","doi-asserted-by":"publisher","first-page":"k5314","DOI":"10.1136\/bmj.k5314","volume":"364","author":"S Chaurasia","year":"2019","unstructured":"Chaurasia S, Sivanandan S, Agarwal R, Ellis S, Sharland M, Sankar MJ (2019) Neonatal sepsis in South Asia: huge burden and spiralling antimicrobial resistance. BMJ 364:k5314\u2013k5314. https:\/\/doi.org\/10.1136\/bmj.k5314","journal-title":"BMJ"},{"issue":"10","key":"5074_CR38","doi-asserted-by":"publisher","first-page":"e752","DOI":"10.1016\/S2214-109X(16)30148-6","volume":"4","author":"Investigators of the Delhi Neonatal Infection Study (DeNIS) collaboration","year":"2016","unstructured":"Investigators of the Delhi Neonatal Infection Study (DeNIS) collaboration (2016) Characterisation and antimicrobial resistance of sepsis pathogens in neonates born in tertiary care centres in Delhi, India: a cohort study. Lancet Glob Health 4(10):e752\u2013760","journal-title":"Lancet Glob Health"},{"issue":"1","key":"5074_CR39","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.pedneo.2017.06.001","volume":"59","author":"D Yusef","year":"2018","unstructured":"Yusef D, Shalakhti T, Awad S, Algharaibeh H, Khasawneh W (2018) Clinical characteristics and epidemiology of sepsis in the neonatal intensive care unit in the era of multi-drug resistant organisms: a retrospective review. Pediatr Neonatol 59(1):35\u201341","journal-title":"Pediatr Neonatol"},{"issue":"9","key":"5074_CR40","doi-asserted-by":"publisher","first-page":"e1003787","DOI":"10.1371\/journal.pmed.1003787","volume":"18","author":"SCH Wen","year":"2021","unstructured":"Wen SCH, Ezure Y, Rolley L, Spurling G, Lau CL, Riaz S et al (2021) Gram-negative neonatal sepsis in low- and lower-middle-income countries and WHO empirical antibiotic recommendations: a systematic review and meta-analysis. PLoS Med 18(9):e1003787","journal-title":"PLoS Med"},{"issue":"2","key":"5074_CR41","doi-asserted-by":"publisher","first-page":"284","DOI":"10.3390\/antibiotics11020284","volume":"11","author":"M Mariani","year":"2022","unstructured":"Mariani M, Parodi A, Minghetti D, Ramenghi LA, Palmero C, Ugolotti E et al (2022) Early and late Onset neonatal Sepsis: epidemiology and effectiveness of empirical antibacterial therapy in a III level neonatal intensive care unit. Antibiot (Basel) 11(2):284","journal-title":"Antibiot (Basel)"},{"issue":"8","key":"5074_CR42","doi-asserted-by":"publisher","first-page":"e0255410","DOI":"10.1371\/journal.pone.0255410","volume":"16","author":"S Solomon","year":"2021","unstructured":"Solomon S, Akeju O, Odumade OA, Ambachew R, Gebreyohannes Z, Van Wickle K et al (2021) Prevalence and risk factors for antimicrobial resistance among newborns with gram-negative sepsis. PLoS ONE 16(8):e0255410","journal-title":"PLoS ONE"},{"key":"5074_CR43","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1186\/s12879-015-0890-3","volume":"15","author":"D Romaniszyn","year":"2015","unstructured":"Romaniszyn D, R\u00f3zanska A, W\u00f3jkowska-Mach J, Chmielarczyk A, Pobiega M, Adamski P et al (2015) Epidemiology, antibiotic consumption and molecular characterisation of Staphylococcus aureus infections\u2013data from the Polish neonatology Surveillance Network, 2009\u20132012. BMC Infect Dis 15:169. https:\/\/doi.org\/10.1186\/s12879-015-0890-3","journal-title":"BMC Infect Dis"},{"issue":"4","key":"5074_CR44","doi-asserted-by":"publisher","first-page":"e914","DOI":"10.1542\/peds.2011-0966","volume":"129","author":"AL Shane","year":"2012","unstructured":"Shane AL, Hansen NI, Stoll BJ, Bell EF, S\u00e1nchez PJ, Shankaran S et al (2012) Methicillin-resistant and susceptible Staphylococcus aureus bacteremia and meningitis in preterm infants. Pediatrics 129(4):e914\u2013922. https:\/\/doi.org\/10.1542\/peds.2011-0966","journal-title":"Pediatrics"},{"issue":"6","key":"5074_CR45","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1097\/INF.0b013e318287fe2a","volume":"32","author":"J W\u00f3jkowska-Mach","year":"2013","unstructured":"W\u00f3jkowska-Mach J, Chmielarczyk A, Borszewska-Kornacka M, Domanska J, Gadzinowski J, Gulczynska E et al (2013) Enterobacteriaceae infections of very low birth weight infants in Polish neonatal intensive care units: resistance and cross-transmission. Pediatr Infect Dis J 32(6):594\u2013598. https:\/\/doi.org\/10.1097\/INF.0b013e318287fe2a","journal-title":"Pediatr Infect Dis J"},{"issue":"3","key":"5074_CR46","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1097\/INF.0000000000002976","volume":"40","author":"N K\u00f6stlin-Gille","year":"2021","unstructured":"K\u00f6stlin-Gille N, H\u00e4rtel C, Haug C, G\u00f6pel W, Zemlin M, M\u00fcller A et al (2021) Epidemiology of early and late onset neonatal Sepsis in very low Birthweight infants. Pediatr Infect Dis J 40(3):255\u2013259","journal-title":"Pediatr Infect Dis J"},{"issue":"3","key":"5074_CR47","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","volume":"18","author":"AP Magiorakos","year":"2012","unstructured":"Magiorakos AP, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG et al (2012) Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect 18(3):268\u2013281","journal-title":"Clin Microbiol Infect"},{"issue":"2","key":"5074_CR48","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1542\/peds.110.2.285","volume":"110","author":"BJ Stoll","year":"2002","unstructured":"Stoll BJ, Hansen N, Fanaroff AA, Wright LL, Carlo WA, Ehrenkranz RA et al (2002) Late-Onset Sepsis in very low Birth Weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics 110(2):285\u2013291","journal-title":"Pediatrics"},{"key":"5074_CR49","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2009\/427682","volume":"2009","author":"SMP Pereira","year":"2009","unstructured":"Pereira SMP, Cardoso MHCA, Figuexeds AL, Mattos H, Rozembaum R, Ferreira VI et al (2009) Sepsis-related mortality of very low Birth Weight Brazilian infants: the role of Pseudomonas aeruginosa. Int J Pediatr 2009:1\u20136","journal-title":"Int J Pediatr"},{"key":"5074_CR50","doi-asserted-by":"publisher","first-page":"e2021389","DOI":"10.1590\/1984-0462\/2023\/41\/2021389","volume":"41","author":"CK Tomo","year":"2023","unstructured":"Tomo CK, Balogun OO, Davidson J, Guinsburg R, de Almeida MFB, de Lopes JM A, et al (2023) Comparison of mortality and survival without major morbidities of very preterm infants with very low birth weight from Japan and Brazil. Rev Paul Pediatr 41:e2021389","journal-title":"Rev Paul Pediatr"},{"issue":"6","key":"5074_CR51","doi-asserted-by":"publisher","first-page":"e2022058813","DOI":"10.1542\/peds.2022-058813","volume":"150","author":"DD Flannery","year":"2022","unstructured":"Flannery DD, Edwards EM, Coggins SA, Horbar JD, Puopolo KM (2022) Late-Onset Sepsis among very Preterm infants. Pediatrics 150(6):e2022058813","journal-title":"Pediatrics"},{"issue":"Suppl 1","key":"5074_CR52","doi-asserted-by":"publisher","first-page":"S67","DOI":"10.3346\/jkms.2015.30.S1.S67","volume":"30","author":"SM Lee","year":"2015","unstructured":"Lee SM, Chang M, Kim KS (2015) Blood Culture Proven Early Onset Sepsis and Late Onset Sepsis in very-low-birth-weight infants in Korea. J Korean Med Sci 30(Suppl 1):S67\u201374. https:\/\/doi.org\/10.3346\/jkms.2015.30.S1.S67","journal-title":"J Korean Med Sci"},{"issue":"Suppl 2","key":"5074_CR53","doi-asserted-by":"publisher","first-page":"S69","DOI":"10.1016\/S0378-3782(12)70019-1","volume":"88","author":"CP Hornik","year":"2012","unstructured":"Hornik CP, Fort P, Clark RH, Watt K, Benjamin DK, Smith PB et al (2012) Early and late onset sepsis in very-low-birth-weight infants from a large group of neonatal intensive care units. Early Hum Dev 88(Suppl 2):S69\u201374. https:\/\/doi.org\/10.1016\/S0378-3782(12)70019-1","journal-title":"Early Hum Dev"},{"issue":"2","key":"5074_CR54","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.jped.2014.07.004","volume":"91","author":"MR Bentlin","year":"2015","unstructured":"Bentlin MR, Rugolo LMSS, Ferrari LSL (2015) Practices related to late-onset sepsis in very low-birth weight preterm infants. J Pediatr (Rio J) 91(2):168\u2013174. https:\/\/doi.org\/10.1016\/j.jped.2014.07.004","journal-title":"J Pediatr (Rio J)"},{"issue":"6","key":"5074_CR55","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1542\/peds.106.6.1387","volume":"106","author":"MG Karlowicz","year":"2000","unstructured":"Karlowicz MG, Buescher ES, Surka AE (2000) Fulminant late-onset Sepsis in a neonatal Intensive Care Unit, 1988\u20131997, and the impact of avoiding empiric vancomycin therapy. Pediatrics 106(6):1387\u20131390","journal-title":"Pediatrics"},{"issue":"2","key":"5074_CR56","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1086\/647066","volume":"16","author":"Hospital Infection Control Practices Advisory Committee (HICPAC)","year":"1995","unstructured":"Hospital Infection Control Practices Advisory Committee (HICPAC) (1995) Recommendations for preventing the spread of Vancomycin Resistance. Infect Control Hosp Epidemiol 16(2):105\u2013113","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"5","key":"5074_CR57","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1016\/j.jped.2016.01.008","volume":"92","author":"RMC Romanelli","year":"2016","unstructured":"Romanelli RMC, Anchieta LM, Silva ACB, de Jesus LA, Rosado V, Clemente WT (2016) Empirical antimicrobial therapy for late-onset sepsis in a neonatal unit with high prevalence of coagulase-negative Staphylococcus. J Pediatr (Rio J) 92(5):472\u2013478. https:\/\/doi.org\/10.1016\/j.jped.2016.01.008","journal-title":"J Pediatr (Rio J)"},{"issue":"3","key":"5074_CR58","doi-asserted-by":"publisher","first-page":"F182","DOI":"10.1136\/archdischild-2011-300097","volume":"97","author":"R Viswanathan","year":"2012","unstructured":"Viswanathan R, Singh AK, Basu S, Chatterjee S, Sardar S, Isaacs D (2012) Multi-drug resistant gram negative bacilli causing early neonatal sepsis in India. Arch Dis Child Fetal Neonatal Ed 97(3):F182\u2013187","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"2","key":"5074_CR59","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.idc.2016.02.004","volume":"30","author":"D van Duin","year":"2016","unstructured":"van Duin D, Paterson DL (2016) Multidrug-resistant Bacteria in the community. Infect Dis Clin North Am 30(2):377\u2013390","journal-title":"Infect Dis Clin North Am"},{"issue":"1","key":"5074_CR60","doi-asserted-by":"publisher","first-page":"F72","DOI":"10.1136\/adc.2005.074963","volume":"91","author":"D Isaacs","year":"2005","unstructured":"Isaacs D (2005) Unnatural selection: reducing antibiotic resistance in neonatal units. Arch Dis Child Fetal Neonatal Ed 91(1):F72\u201374","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"2","key":"5074_CR61","doi-asserted-by":"publisher","first-page":"e1921124","DOI":"10.1001\/jamanetworkopen.2019.21124","volume":"3","author":"JA Bielicki","year":"2020","unstructured":"Bielicki JA, Sharland M, Heath PT, Walker AS, Agarwal R, Turner P et al (2020) Evaluation of the Coverage of 3 antibiotic regimens for neonatal Sepsis in the hospital setting across Asian countries. JAMA Netw Open 3(2):e1921124\u2013e1921124. https:\/\/doi.org\/10.1001\/jamanetworkopen.2019.21124","journal-title":"JAMA Netw Open"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-025-05074-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-025-05074-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-025-05074-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T12:54:29Z","timestamp":1746708869000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-025-05074-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,21]]},"references-count":61,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["5074"],"URL":"https:\/\/doi.org\/10.1007\/s10096-025-05074-z","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"type":"print","value":"0934-9723"},{"type":"electronic","value":"1435-4373"}],"subject":[],"published":{"date-parts":[[2025,2,21]]},"assertion":[{"value":"8 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of the State University of Campinas.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The informed consent was waived by the Institutional Review Board since this was a retrospective analysis of existing clinical data.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The informed consent was waived by the Institutional Review Board since this was a retrospective analysis of existing clinical data.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}