{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:24:42Z","timestamp":1787027082780,"version":"build-2736575974"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100003252","name":"Lund University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003252","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Previous studies on causative pathogens in peritonsillar abscesses have yielded varying results. However, Group A streptococci (GAS) and <jats:italic>Fusobacterium necrophorum<\/jats:italic> have been identified frequently. The aim of this study was to investigate pathogens in peritonsillar abscesses in patients tested for both \u00df-hemolytic streptococci and <jats:italic>F. necrophorum<\/jats:italic>, and to investigate associations between pathogens and clinical outcome.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Method<\/jats:title>\n            <jats:p>This retrospective observational study included all patients in the Sk\u00e5ne Region, Sweden (population 1.4\u00a0million) with a diagnosis of peritonsillar abscess between 2016 and 20, and in whom tests were performed for both \u00df-hemolytic streptococci (culture) and <jats:italic>F. necrophorum<\/jats:italic> (PCR). Exclusion criteria included previous (30 days) purulent complication to pharyngotonsillitis or antibiotic therapy. Chart review from 30 days prior to 6 months after the index visit was performed. Logistic regression was performed to evaluate the association between pathogens and complications, with negative microbiological findings set as reference category. Complications were defined as a composite outcome (0\/1) of recurrent pharyngotonsillitis\/peritonsillar abscess, other pharyngeal abscess or septic complications within 30 days (early), and 1\u20136 months (late).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>In a total of 637 patients, <jats:italic>F. necrophorum<\/jats:italic> was identified in 210 (33%), GAS in 159 (28%) and GCS\/GGS in 40 (6%) patients. <jats:italic>F. necrophorum<\/jats:italic> was most common in adolescents and young adults. Only <jats:italic>F. necrophorum<\/jats:italic> was associated with the development of either of early (OR 3.8 (2.0-7.1 95%CI)) and late complications (OR 2.5 (95%CI 1.3\u20134.9).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>\n              <jats:italic>F. necrophorum<\/jats:italic> was the most commonly identified pathogen in peritonsillar abscesses. It was also the only pathogen associated with the development of complications.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s10096-025-05156-y","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T08:51:02Z","timestamp":1747212662000},"page":"1925-1933","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Association between clinical outcome and microbiological findings in peritonsillar abscess - an observational study"],"prefix":"10.1007","volume":"44","author":[{"given":"Elin","family":"Lindberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Hermansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Nygren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Gisselsson-Sol\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,14]]},"reference":[{"key":"5156_CR1","doi-asserted-by":"crossref","unstructured":"Esposito S, De Guido C, Pappalardo M, Laudisio S, Meccariello G, Capoferri G et al (2022) Retropharyngeal, parapharyngeal and peritonsillar abscesses. 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