{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:28:30Z","timestamp":1786980510422,"version":"build-2736575974"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We describe an atypical case of mpox virus (MPXV) infection in a Polish patient, with a focus on clinical presentation, virological characterisation, and the phylogenetic placement of the viral isolate within the emerging C.1 lineage of Clade IIb. The report aims to contribute to a better understanding of MPXV lineage-specific disease features and viral evolution in non-endemic settings. The patient presented with numerous localised lesions and minimal systemic symptoms. Genomic analysis confirmed infection with an MPXV C.1 lineage of Clade IIb responsible for the 2022\u20132025 global outbreaks. Infection with C.1 lineage may lead to atypical presentations, particularly in immunocompetent individuals. Continued genomic surveillance and clade-specific clinical correlation are essential for accurate diagnosis, risk stratification, and public health response.<\/jats:p>","DOI":"10.1007\/s10096-025-05346-8","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T15:19:45Z","timestamp":1763479185000},"page":"885-889","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["An atypical case of infection with the Mpox virus clade IIb lineage C.1 \u2013 clinical and virological findings"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2012-7223","authenticated-orcid":false,"given":"Pawel","family":"Zmora","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1627-8456","authenticated-orcid":false,"given":"Blazej","family":"Rozplochowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7783-4554","authenticated-orcid":false,"given":"Monika","family":"Gazecka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9404-5100","authenticated-orcid":false,"given":"Szymon","family":"Nowak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8276-3746","authenticated-orcid":false,"given":"Dagny","family":"Lorent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2087-3410","authenticated-orcid":false,"given":"Arleta","family":"Kowala-Piaskowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,18]]},"reference":[{"key":"5346_CR1","unstructured":"Mpox [Internet] [cited 2025 Aug 1]. Available from: https:\/\/www.who.int\/health-topics\/mpox"},{"key":"5346_CR2","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.ijid.2023.05.014","volume":"133","author":"M Gazecka","year":"2023","unstructured":"Gazecka M, Sniezek J, Maciolek K, Kowala-Piaskowska A, Zmora P (2023) Mpox virus detection in the wastewater and the number of hospitalized patients in the Poznan metropolitan area, Poland. Int J Infect Dis 133:75\u201377","journal-title":"Int J Infect Dis"},{"key":"5346_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.onehlt.2025.101030","volume":"20","author":"A Bogacka","year":"2025","unstructured":"Bogacka A, Wroczynska A, Rymer W, Grzesiowski P, Kant R, Grzybek M et al (2025) Mpox unveiled: global epidemiology, treatment advances, and prevention strategies. 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Euro Surveill 29:2400486","journal-title":"Euro Surveill"},{"key":"5346_CR6","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2024.1360586","volume":"14","author":"E Alakunle","year":"2024","unstructured":"Alakunle E, Kolawole D, Diaz-C\u00e1nova D, Alele F, Adegboye O, Moens U et al (2024) A comprehensive review of Monkeypox virus and Mpox characteristics. Front Cell Infect Microbiol 14:1360586","journal-title":"Front Cell Infect Microbiol"},{"key":"5346_CR7","doi-asserted-by":"publisher","first-page":"1502","DOI":"10.1016\/j.cmi.2023.07.011","volume":"29","author":"T Okwor","year":"2023","unstructured":"Okwor T, Mbala PK, Evans DH, Kindrachuk J (2023) A contemporary review of clade-specific virological differences in Monkeypox viruses. Clin Microbiol Infect 29:1502\u20131507","journal-title":"Clin Microbiol Infect"},{"key":"5346_CR8","doi-asserted-by":"publisher","first-page":"e2220415120","DOI":"10.1073\/pnas.2220415120","volume":"120","author":"JL Americo","year":"2023","unstructured":"Americo JL, Earl PL, Moss B (2023) Virulence differences of mpox (monkeypox) virus clades I, IIa, and IIb.1 in a small animal model. Proc Nat Acad Sci 120:e2220415120","journal-title":"Proc Nat Acad Sci"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-025-05346-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-025-05346-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-025-05346-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T13:39:40Z","timestamp":1773495580000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-025-05346-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,18]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["5346"],"URL":"https:\/\/doi.org\/10.1007\/s10096-025-05346-8","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,18]]},"assertion":[{"value":"1 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval was waived by the local Ethics Committee of University A in view of the retrospective nature of the study, and all the procedures were part of the routine care.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Written informed consent was obtained from the patient.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The participant has consented to the submission of the case report to the journal.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}