{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T14:14:24Z","timestamp":1788358464212,"version":"build-2803163510"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Clin Microbiol Infect Dis"],"DOI":"10.1007\/s10096-026-05659-2","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T13:30:56Z","timestamp":1788355856000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Real-world impact of multiplex PCR testing on antimicrobial management in patients evaluated for sexually transmitted infections"],"prefix":"10.1007","author":[{"given":"\u00d6zge","family":"\u00d6zgen-Top","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u0131nar","family":"Aysert-Y\u0131ld\u0131z","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan Sel\u00e7uk","family":"\u00d6zger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma","family":"G\u00fc\u00e7l\u00fc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma Zehra","family":"\u015eahi\u0307n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elif Ay\u00e7a","family":"\u015eahi\u0307n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe Meltem","family":"Yal\u0131nay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ender Cem","family":"Bulut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erhan","family":"Demi\u0307rda\u011f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esin","family":"\u015eenol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,2]]},"reference":[{"key":"5659_CR1","unstructured":"Guidelines for the management of symptomatic sexually transmitted infections [Internet] (2021) Jun Geneva: World Health Organization"},{"issue":"3","key":"5659_CR2","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1111\/ddg.13804","volume":"17","author":"S Buder","year":"2019","unstructured":"Buder S, Sch\u00f6fer H, Meyer T, Bremer V, Kohl PK, Skaletz-Rorowski A et al (2019) Bacterial sexually transmitted infections. J Dtsch Dermatol Ges 17(3):287\u2013315.https:\/\/doi.org\/10.1111\/ddg.13804","journal-title":"J Dtsch Dermatol Ges"},{"key":"5659_CR3","doi-asserted-by":"publisher","unstructured":"Tuddenham S, Hamill MM, Ghanem KG (2022) Diagnosis and treatment of sexually transmitted infections: a review. JAMA 11;327(2):161\u2013172. https:\/\/doi.org\/10.1001\/jama.2021.23487","DOI":"10.1001\/jama.2021.23487"},{"key":"5659_CR4","doi-asserted-by":"publisher","unstructured":"Wagenlehner FM, Brockmeyer NH, Discher T, Friese K, Wichelhaus TA (2016) The presentation, diagnosis, and treatment of sexually transmitted infections. Dtsch Arztebl Int 11;113(1\u201302):11\u201322. https:\/\/doi.org\/10.3238\/arztebl.2016.0011","DOI":"10.3238\/arztebl.2016.0011"},{"issue":"3","key":"5659_CR5","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1128\/JCM.03370-14","volume":"53","author":"B Ber\u00e7ot","year":"2015","unstructured":"Ber\u00e7ot B, Amarsy R, Goubard A, Aparicio C, Loeung HU, Segouin C et al (2015) Assessment of coinfection of sexually transmitted pathogen microbes by use of the anyplex II STI-7 molecular kit. J Clin Microbiol 53(3):991\u2013993. https:\/\/doi.org\/10.1128\/JCM.03370-14","journal-title":"J Clin Microbiol"},{"issue":"2","key":"5659_CR6","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1024\/0040-5930\/a000647","volume":"72","author":"R Auckenthaler","year":"2015","unstructured":"Auckenthaler R, Risch M (2015) Verdr\u00e4ngt Multiplex PCR den klassischen Kulturnachweis in der Mikrobiologie? [Do Multiplex PCR techniques displace classical cultures in microbiology?]. Ther Umsch 72(2):77\u201385. German. https:\/\/doi.org\/10.1024\/0040-5930\/a000647","journal-title":"Ther Umsch"},{"issue":"14","key":"5659_CR7","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1177\/0956462415615775","volume":"27","author":"JD Kriesel","year":"2016","unstructured":"Kriesel JD, Bhatia AS, Barrus C, Vaughn M, Gardner J, Crisp RJ (2016) Multiplex PCR testing for nine different sexually transmitted infections. Int J STD AIDS 27(14):1275\u20131282","journal-title":"Int J STD AIDS"},{"key":"5659_CR8","doi-asserted-by":"publisher","DOI":"10.6002\/ect.2017.0232","author":"M Sarier","year":"2018","unstructured":"Sarier M, Sepin Ozen N, Guler H, Duman I, Y\u00fcksel Y, Tekin S et al (2018) Prevalence of sexually transmitted diseases in asymptomatic renal transplant recipients. Exp Clin Transpl. https:\/\/doi.org\/10.6002\/ect.2017.0232","journal-title":"Exp Clin Transpl"},{"issue":"7","key":"5659_CR9","doi-asserted-by":"publisher","first-page":"930","DOI":"10.3390\/healthcare11070930","volume":"11","author":"H Kirkoyun Uysal","year":"2023","unstructured":"Kirkoyun Uysal H, Koksal MO, Sarsar K, Ilktac M, Isik Z, Akgun Karapinar DB et al (2023) Prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium among patients with urogenital symptoms in Istanbul. Healthc (Basel) 11(7):930. https:\/\/doi.org\/10.3390\/healthcare11070930","journal-title":"Healthc (Basel)"},{"issue":"2","key":"5659_CR10","first-page":"16","volume":"12","author":"NE Beayni","year":"2021","unstructured":"Beayni NE, Hamad L, Nakad C, Keleshian S, Yazbek SN, Mahfouz R (2021) Molecular prevalence of eight different sexually transmitted infections in a Lebanese major tertiary care center: impact on public health. Int J Mol Epidemiol Genet 12(2):16\u201323","journal-title":"Int J Mol Epidemiol Genet"},{"issue":"4","key":"5659_CR11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.15585\/mmwr.rr7004a1","volume":"70","author":"KA Workowski","year":"2021","unstructured":"Workowski KA, Bachmann LH, Chan PA, Johnston CM, Muzny CA, Park I et al (2021) Sexually transmitted infections treatment guidelines, 2021. MMWR Recomm Rep 70(4):1\u2013187. https:\/\/doi.org\/10.15585\/mmwr.rr7004a1","journal-title":"MMWR Recomm Rep"},{"issue":"11","key":"5659_CR12","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1111\/jdv.15146","volume":"32","author":"P Horner","year":"2018","unstructured":"Horner P, Donders G, Cusini M, Gomberg M, Jensen JS, Unemo M (2018) Should we be testing for urogenital Mycoplasma hominis, Ureaplasma parvum and Ureaplasma urealyticum in men and women? - a position statement from the European STI Guidelines Editorial Board. J Eur Acad Dermatol Venereol 32(11):1845\u20131851. https:\/\/doi.org\/10.1111\/jdv.15146","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"7","key":"5659_CR13","doi-asserted-by":"publisher","first-page":"e005670","DOI":"10.1136\/bmjgh-2021-005670","volume":"6","author":"F Naeem","year":"2021","unstructured":"Naeem F, Karellis A, Nair S, Routy JP, Yansouni CP, Kim J et al (2021) Multiplexed technologies for sexually transmitted infections: global evidence on patient-centered and clinical health outcomes. BMJ Glob Health 6(7):e005670. https:\/\/doi.org\/10.1136\/bmjgh-2021-005670","journal-title":"BMJ Glob Health"},{"issue":"4","key":"5659_CR14","doi-asserted-by":"publisher","first-page":"e303","DOI":"10.1016\/S2666-5247(21)00191-9","volume":"3","author":"A Karellis","year":"2022","unstructured":"Karellis A, Naeem F, Nair S, Mallya SD, Routy JP, Gahagan J et al (2022) Multiplexed rapid technologies for sexually transmitted infections: a systematic review. Lancet Microbe 3(4):e303\u2013e315. https:\/\/doi.org\/10.1016\/S2666-5247(21)00191-9","journal-title":"Lancet Microbe"},{"issue":"1","key":"5659_CR15","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1186\/s12879-026-13232-7","volume":"26","author":"J Kim","year":"2026","unstructured":"Kim J, Cho J, Go U, Oh GY (2026) Epidemiological analysis of sexually transmitted infections pathogens and related microorganisms in South Korea: coinfection patterns and pathogen correlations. BMC Infect Dis 26(1):1028. https:\/\/doi.org\/10.1186\/s12879-026-13232-7","journal-title":"BMC Infect Dis"}],"container-title":["European Journal of Clinical Microbiology &amp; Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-026-05659-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10096-026-05659-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10096-026-05659-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T13:30:57Z","timestamp":1788355857000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10096-026-05659-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,2]]},"references-count":15,"alternative-id":["5659"],"URL":"https:\/\/doi.org\/10.1007\/s10096-026-05659-2","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,2]]},"assertion":[{"value":"24 June 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Informed consent to participate was waived by Gazi University Ethics Committee due to the retrospective nature of the study. For patients whose data could not be fully obtained from retrospective records, verbal informed consent was obtained by contacting patients via the phone numbers registered in the hospital system.","order":1,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable. This study does not contain any individual person\u2019s identifiable data, images, or personal information requiring consent for publication.","order":2,"name":"Ethics","label":"Consent to publish","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was previously presented as an oral presentation at the national KL\u0130M\u0130K 2024 Congress which was held on 6\u20139 March in Antalya\/Turkiye.","order":3,"name":"Ethics","label":"Transparency declarations","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":5,"name":"Ethics","label":"Clinical trial number","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the Gazi University Ethics Committee (Decision No. 11, June 6, 2023).","order":6,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}}]}}