{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T11:50:31Z","timestamp":1792842631004,"version":"4.5.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2008,12,5]],"date-time":"2008-12-05T00:00:00Z","timestamp":1228435200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"published-print":{"date-parts":[[2009,9]]},"DOI":"10.1007\/s10103-008-0630-7","type":"journal-article","created":{"date-parts":[[2008,12,4]],"date-time":"2008-12-04T04:13:46Z","timestamp":1228364026000},"page":"729-734","source":"Crossref","is-referenced-by-count":33,"title":["Optimal conditions for successful ablation of high-grade dysplasia in Barrett\u2019s oesophagus using aminolaevulinic acid photodynamic therapy"],"prefix":"10.1007","volume":"24","author":[{"given":"Gary D.","family":"Mackenzie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason M.","family":"Dunn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. R.","family":"Selvasekar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Alexander","family":"Mosse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally M.","family":"Thorpe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco R.","family":"Novelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen G.","family":"Bown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence B.","family":"Lovat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,12,5]]},"reference":[{"key":"630_CR1","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1046\/j.1365-2036.2003.01521.x","volume":"17","author":"A Newnham","year":"2003","unstructured":"Newnham A, Quinn MJ, Babb P et al (2003) Trends in the subsite and morphology of oesophageal and gastric cancer in England and Wales 1971\u20131998. Aliment Pharmacol Ther 17:665\u2013676. doi: 10.1046\/j.1365\u20132036.2003.01521.x","journal-title":"Aliment Pharmacol Ther"},{"key":"630_CR2","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1053\/hupa.2001.23511","volume":"32","author":"E Montgomery","year":"2001","unstructured":"Montgomery E, Goldblum JR, Greenson JK et al (2001) Dysplasia as a predictive marker for invasive carcinoma in Barrett esophagus: a follow-up study based on 138 cases from a diagnostic variability study. Hum Pathol 32:379\u2013388. doi: 10.1053\/hupa.2001.23511","journal-title":"Hum Pathol"},{"key":"630_CR3","first-page":"1669","volume":"95","author":"BJ Reid","year":"2000","unstructured":"Reid BJ, Levine DS, Longton G et al (2000) Predictors of progression to cancer in Barrett\u2019s esophagus: baseline histology and flow cytometry identify low- and high-risk patient subsets. Am J Gastroenterol 95:1669\u20131676","journal-title":"Am J Gastroenterol"},{"key":"630_CR4","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1053\/gast.2001.25065","volume":"120","author":"TG Schnell","year":"2001","unstructured":"Schnell TG, Sontag SJ, Chejfec G et al (2001) Long-term nonsurgical management of Barrett\u2019s esophagus with high-grade dysplasia. Gastroenterology 120:1607\u20131619. doi: 10.1053\/gast.2001.25065","journal-title":"Gastroenterology"},{"key":"630_CR5","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.gie.2006.12.037","volume":"66","author":"BF Overholt","year":"2007","unstructured":"Overholt BF, Wang KK, Burdick JS et al (2007) Five-year efficacy and safety of photodynamic therapy with Photofrin in Barrett\u2019s high-grade dysplasia. Gastrointest Endosc 66:460\u2013468. doi: 10.1016\/j.gie.2006.12.037","journal-title":"Gastrointest Endosc"},{"key":"630_CR6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0016-5107(99)70437-2","volume":"49","author":"BF Overholt","year":"1999","unstructured":"Overholt BF, Panjehpour M, Haydek JM (1999) Photodynamic therapy for Barrett\u2019s esophagus: follow-up in 100 patients. Gastrointest Endosc 49:1\u20137. doi: 10.1016\/S0016\u20135107(99)70437\u20132","journal-title":"Gastrointest Endosc"},{"key":"630_CR7","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1067\/mge.2003.327","volume":"58","author":"BF Overholt","year":"2003","unstructured":"Overholt BF, Panjehpour M, Halberg DL (2003) Photodynamic therapy for Barrett\u2019s esophagus with dysplasia and\/or early stage carcinoma: long-term results. Gastrointest Endosc 58:183\u2013188. doi: 10.1067\/mge.2003.327","journal-title":"Gastrointest Endosc"},{"key":"630_CR8","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1136\/gut.38.1.71","volume":"38","author":"CS Loh","year":"1996","unstructured":"Loh CS, MacRobert AJ, Buonaccorsi G et al (1996) Mucosal ablation using photodynamic therapy for the treatment of dysplasia: an experimental study in the normal rat stomach. Gut 38:71\u201378. doi: 10.1136\/gut.38.1.71","journal-title":"Gut"},{"key":"630_CR9","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1136\/gut.36.1.67","volume":"36","author":"J Regula","year":"1995","unstructured":"Regula J, MacRobert AJ, Gorchein A et al (1995) Photosensitisation and photodynamic therapy of oesophageal, duodenal, and colorectal tumours using 5 aminolaevulinic acid induced protoporphyrin IX\u2014a pilot study. Gut 36:67\u201375. doi: 10.1136\/gut.36.1.67","journal-title":"Gut"},{"key":"630_CR10","doi-asserted-by":"crossref","unstructured":"Mackenzie GD, Jamieson NF, Novelli MR et al (2008) How light dosimetry influences the efficacy of photodynamic therapy with 5-aminolaevulinic acid for ablation of high-grade dysplasia in Barrett\u2019s esophagus. Lasers Med Sci 23:203\u2013210","DOI":"10.1007\/s10103-007-0473-7"},{"key":"630_CR11","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1055\/s-2003-39676","volume":"35","author":"R Ackroyd","year":"2003","unstructured":"Ackroyd R, Kelty CJ, Brown NJ et al (2003) Eradication of dysplastic Barrett\u2019s oesophagus using photodynamic therapy: long-term follow-up. Endoscopy 35:496\u2013501. doi: 10.1055\/s-2003\u201339676","journal-title":"Endoscopy"},{"key":"630_CR12","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1055\/s-2005-861198","volume":"37","author":"F Peters","year":"2005","unstructured":"Peters F, Kara M, Rosmolen W et al (2005) Poor results of 5-aminolevulinic acid-photodynamic therapy for residual high-grade dysplasia and early cancer in barrett esophagus after endoscopic resection. Endoscopy 37:418\u2013424. doi: 10.1055\/s-2005\u2013861198","journal-title":"Endoscopy"},{"key":"630_CR13","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1136\/gut.47.2.251","volume":"47","author":"RJ Schlemper","year":"2000","unstructured":"Schlemper RJ, Riddell RH, Kato Y et al (2000) The Vienna classification of gastrointestinal epithelial neoplasia. Gut 47:251\u2013255. doi: 10.1136\/gut.47.2.251","journal-title":"Gut"},{"key":"630_CR14","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1016\/S0022-5347(05)66239-8","volume":"165","author":"R Waidelich","year":"2001","unstructured":"Waidelich R, Stepp H, Baumgartner R et al (2001) Clinical experience with 5-aminolevulinic acid and photodynamic therapy for refractory superficial bladder cancer. J Urol 165:1904\u20131907. doi: 10.1016\/S0022\u20135347(05)66239\u20138","journal-title":"J Urol"},{"key":"630_CR15","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1046\/j.1442-2050.2000.00067.x","volume":"13","author":"R Ackroyd","year":"2000","unstructured":"Ackroyd R, Brown NJ, Davis MF et al (2000) Aminolevulinic acid-induced photodynamic therapy: safe and effective ablation of dysplasia in Barrett\u2019s esophagus. Dis Esophagus 13:18\u201322. doi: 10.1046\/j.1442\u20132050.2000.00067.x","journal-title":"Dis Esophagus"},{"key":"630_CR16","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0016-5107(05)00333-0","volume":"62","author":"O Pech","year":"2005","unstructured":"Pech O, Gossner L, May A et al (2005) Long-term results of photodynamic therapy with 5-aminolevulinic acid for superficial Barrett\u2019s cancer and high-grade intraepithelial neoplasia. Gastrointest Endosc 62:24\u201330. doi: 10.1016\/S0016\u20135107(05)00333\u20130","journal-title":"Gastrointest Endosc"},{"key":"630_CR17","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/S0016-5107(05)00063-5","volume":"61","author":"FP Peters","year":"2005","unstructured":"Peters FP, Kara MA, Rosmolen WD et al (2005) Endoscopic treatment of high-grade dysplasia and early stage cancer in Barrett\u2019s esophagus. Gastrointest Endosc 61:506\u2013514. doi: 10.1016\/S0016\u20135107(05)00063\u20135","journal-title":"Gastrointest Endosc"},{"key":"630_CR18","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/S0140-6736(96)03054-1","volume":"348","author":"H Barr","year":"1996","unstructured":"Barr H, Shepherd NA, Dix A et al (1996) Eradication of high-grade dysplasia in columnar-lined (Barrett\u2019s) oesophagus by photodynamic therapy with endogenously generated protoporphyrin IX. Lancet 348:584\u2013585. doi: 10.1016\/S0140\u20136736(96)03054\u20131","journal-title":"Lancet"},{"key":"630_CR19","doi-asserted-by":"crossref","first-page":"P251","DOI":"10.1016\/S0016-5107(04)01121-6","volume":"59","author":"DG Forcione","year":"2004","unstructured":"Forcione DG, Hasan T, Ortel BJ et al (2004) Optimization of aminolevulinic acid-based photodynamic therapy of Barrett\u2019s esophagus with high grade dysplasia. Gastrointest Endosc 59:P251. doi: 10.1016\/S0016\u20135107(04)01121\u20136","journal-title":"Gastrointest Endosc"},{"key":"630_CR20","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1136\/gut.2003.028860","volume":"53","author":"M Hage","year":"2004","unstructured":"Hage M, Siersema PD, van Dekken H et al (2004) 5-Aminolevulinic acid photodynamic therapy versus argon plasma coagulation for ablation of Barrett\u2019s oesophagus: a randomised trial. Gut 53:785\u2013790. doi: 10.1136\/gut.2003.028860","journal-title":"Gut"},{"key":"630_CR21","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/S0016-5085(98)70527-X","volume":"114","author":"L Gossner","year":"1998","unstructured":"Gossner L, Stolte M, Sroka R et al (1998) Photodynamic ablation of high-grade dysplasia and early cancer in Barrett\u2019s esophagus by means of 5-aminolevulinic acid. Gastroenterology 114:448\u2013455. doi: 10.1016\/S0016\u20135085(98)70527-X","journal-title":"Gastroenterology"},{"key":"630_CR22","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1111\/j.1365-2036.2004.02277.x","volume":"20","author":"CJ Kelty","year":"2004","unstructured":"Kelty CJ, Ackroyd R, Brown NJ et al (2004) Endoscopic ablation of Barrett\u2019s oesophagus: a randomized-controlled trial of photodynamic therapy vs. argon plasma coagulation. Aliment Pharmacol Ther 20:1289\u20131296. doi: 10.1111\/j.1365\u20132036.2004.02277.x","journal-title":"Aliment Pharmacol Ther"},{"key":"630_CR23","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1007\/s00464-003-9062-4","volume":"18","author":"CJ Kelty","year":"2004","unstructured":"Kelty CJ, Ackroyd R, Brown NJ et al (2004) Comparison of high- vs low-dose 5-aminolevulinic acid for photodynamic therapy of Barrett\u2019s esophagus. Surg Endosc 18:452\u2013458. doi: 10.1007\/s00464\u2013003\u20139062\u20134","journal-title":"Surg Endosc"},{"key":"630_CR24","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1136\/gut.47.5.612","volume":"47","author":"R Ackroyd","year":"2000","unstructured":"Ackroyd R, Brown NJ, Davis MF et al (2000) Photodynamic therapy for dysplastic Barrett\u2019s oesophagus: a prospective, double blind, randomised, placebo controlled trial. Gut 47:612\u2013617. doi: 10.1136\/gut.47.5.612","journal-title":"Gut"},{"key":"630_CR25","first-page":"A14","volume":"57","author":"GD Mackenzie","year":"2008","unstructured":"Mackenzie GD, Dunn JM, Novelli MR et al (2008) Preliminary results of a randomised controlled trial into the safety and efficacy of ala versus photofrin photodynamic therapy for high grade dysplasia in Barrett\u2019s oesophagus. Gut 57:A14","journal-title":"Gut"},{"key":"630_CR26","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.gie.2006.09.033","volume":"65","author":"VK Sharma","year":"2007","unstructured":"Sharma VK, Wang KK, Overholt BF et al (2007) Balloon-based, circumferential, endoscopic radiofrequency ablation of Barrett\u2019s esophagus: 1-year follow-up of 100 patients. Gastrointest Endosc 65:185\u2013195. doi: 10.1016\/j.gie.2006.09.033","journal-title":"Gastrointest Endosc"},{"key":"630_CR27","first-page":"AB147","volume":"65","author":"RI Rothstein","year":"2007","unstructured":"Rothstein RI, Chang K, Overholt BF et al (2007) Focal ablation for treatment of dysplastic and non-dysplastic Barrett esophagus: safety profile and initial experience with the Halo90 device in 508 cases. Gastrointest Endosc 65:AB147. doi: 10.1016\/j.gie.2007.03.198","journal-title":"Gastrointest Endosc"}],"container-title":["Lasers in Medical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-008-0630-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10103-008-0630-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-008-0630-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T05:42:52Z","timestamp":1559108572000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10103-008-0630-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12,5]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["630"],"URL":"https:\/\/doi.org\/10.1007\/s10103-008-0630-7","relation":{},"ISSN":["0268-8921","1435-604X"],"issn-type":[{"value":"0268-8921","type":"print"},{"value":"1435-604X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12,5]]}}}