{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T04:32:38Z","timestamp":1783571558815,"version":"3.55.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,2,13]],"date-time":"2013-02-13T00:00:00Z","timestamp":1360713600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1007\/s10103-013-1280-y","type":"journal-article","created":{"date-parts":[[2013,2,12]],"date-time":"2013-02-12T01:07:25Z","timestamp":1360631245000},"page":"85-90","source":"Crossref","is-referenced-by-count":28,"title":["Low-level light-emitting diode therapy increases mRNA expressions of IL-10 and type I and III collagens on Achilles tendinitis in rats"],"prefix":"10.1007","volume":"29","author":[{"given":"Murilo","family":"Xavier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato Aparecido","family":"de Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviane Ara\u00fajo","family":"Pires","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Paula","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fl\u00e1vio","family":"Aimbire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Jos\u00e9 Ant\u00f4nio","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regiane","family":"Albertini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Balbin","family":"Villaverde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,2,13]]},"reference":[{"key":"1280_CR1","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1177\/107110070602700415","volume":"27","author":"CP Chiodo","year":"2006","unstructured":"Chiodo CP, Wilson MG (2006) Current concepts review: acute ruptures of the Achilles tendon. Foot Ankle Int 27:305\u2013313","journal-title":"Foot Ankle Int"},{"key":"1280_CR2","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1111\/j.1600-0838.1997.tb00125.x","volume":"7","author":"R Sandmeier","year":"1997","unstructured":"Sandmeier R, Renstr\u00f6m PA (1997) Diagnosis and treatment of chronic tendon disorders in sports. Scand J Med Sci Sports 7:96\u2013106","journal-title":"Scand J Med Sci Sports"},{"key":"1280_CR3","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1097\/JSA.0b013e3181a3d625","volume":"17","author":"UG Longo","year":"2009","unstructured":"Longo UG, Ronga M, Maffulli N (2009) Achilles tendinopathy. Sports Med Arthrosc 17:112\u2013126. doi:\n                    10.1097\/JSA.0b013e3181a3d625","journal-title":"Sports Med Arthrosc"},{"key":"1280_CR4","first-page":"265","volume":"318","author":"SH Liu","year":"1995","unstructured":"Liu SH, Yang RS, Al-Shaikh R, Lane JM (1995) Collagen in tendon, ligament, and bone healing. A current review. Clin Orthop 318:265\u2013278","journal-title":"Clin Orthop"},{"key":"1280_CR5","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1002\/jor.20800","volume":"27","author":"CH Chen","year":"2009","unstructured":"Chen CH, Tsai JL, Wang YH, Lee CL, Chen JK, Huang MH (2009) Low-level laser irradiation promotes cell proliferation and mRNA expression of type I collagen and decorin in porcine Achilles tendon fibroblasts in vitro. J Orthop Res 27:646\u2013650. doi:\n                    10.1002\/jor.20800","journal-title":"J Orthop Res"},{"key":"1280_CR6","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.gene.2006.08.027","volume":"386","author":"BP Thampatty","year":"2007","unstructured":"Thampatty BP, LiH IHJ, Wang JH (2007) EP4 receptor regulates collagen type-I, MMP-1, and MMP-3 gene expression in human tendon fibroblasts in response to IL-1 beta treatment. Gene 386:154\u2013161. doi:\n                    10.1016\/j.gene.2006.08.027","journal-title":"Gene"},{"key":"1280_CR7","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1002\/jor.21079","volume":"28","author":"T John","year":"2010","unstructured":"John T, Lodka D, Kohl B, Ertel W, Jammrath J, Conrad C, Stoll C, Busch C, Schulze-Tanzil G (2010) Effect of pro-inflammatory and immunoregulatory cytokines on human tenocytes. J Orthop Res 28:1071\u20131077. doi:\n                    10.1002\/jor.21079","journal-title":"J Orthop Res"},{"key":"1280_CR8","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1111\/j.1600-0838.2010.01265.x","volume":"21","author":"G Schulze-Tanzil","year":"2011","unstructured":"Schulze-Tanzil G, Al-Sadi O, Wiegand E, Ertel W, Busch C, Kohl B, Pufe (2011) The role of pro-inflammatory and immune regulatory cytokines in tendon healing and rupture: new insights. Scand J Med Sci Sports 21:337\u2013351. doi:\n                    10.1111\/j.1600-0838.2010.01265.x","journal-title":"Scand J Med Sci Sports"},{"key":"1280_CR9","doi-asserted-by":"publisher","first-page":"1682","DOI":"10.1016\/j.ultrasmedbio.2010.06.012","volume":"36","author":"AL Maia Filho","year":"2010","unstructured":"Maia Filho AL, Villaverde AB, Munin E, Aimbire F, Albertini R (2010) Comparative study of the topical application of Aloe vera gel, therapeutic ultrasound and phonophoresis on the tissue repair in collagenase-induced rat tendinitis. Ultrasound Med Biol 36:1682\u20131690","journal-title":"Ultrasound Med Biol"},{"key":"1280_CR10","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1111\/j.1532-950X.2011.00800.x","volume":"40","author":"RW Waguespack","year":"2011","unstructured":"Waguespack RW, Burba DJ, Hubert JD, Vidal MA, Lomax LG, Chirgwin SR, Lopez MJ (2011) Effects of extracorporeal shock wave therapy on desmitis of the accessory ligament of the deep digital flexor tendon in the horse. Vet Surg 40:450\u2013456. doi:\n                    10.1111\/j.1532-950X.2011.00800.x","journal-title":"Vet Surg"},{"key":"1280_CR11","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1097\/JSM.0b013e31818ef090","volume":"19","author":"RA Magnussen","year":"2009","unstructured":"Magnussen RA, Dunn WR, Thomson AB (2009) Nonoperative treatment of midportion Achilles tendinopathy: a systematic review. Clin J Sport Med 19:54\u201364. doi:\n                    10.1097\/JSM.0b013e31818ef090","journal-title":"Clin J Sport Med"},{"key":"1280_CR12","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1007\/s10103-010-0811-z","volume":"26","author":"D Pires","year":"2011","unstructured":"Pires D, Xavier M, Ara\u00fajo T, Silva JA Jr, Aimbire F, Albertini R (2011) Low-level laser therapy (LLLT; 780\u00a0nm) acts differently on mRNA expression of anti- and pro-inflammatory mediators in an experimental model of collagenase-induced tendinitis in rat. Lasers Med Sci 26:85\u201394. doi:\n                    10.1007\/s10103-010-0811-z","journal-title":"Lasers Med Sci"},{"key":"1280_CR13","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1007\/s10103-008-0607-6","volume":"24","author":"HL Casalechi","year":"2009","unstructured":"Casalechi HL, Nicolau RA, Casalechi VL, Silveira-J\u00fanior L, Paula AMB, Pacheco MTT (2009) The effects of low level light emitting diode on the repair process of Achilles tendon therapy in rats. Lasers Med Sci 24:659\u2013665. doi:\n                    10.1007\/s10103-008-0607-6","journal-title":"Lasers Med Sci"},{"key":"1280_CR14","doi-asserted-by":"publisher","first-page":"358","DOI":"10.2203\/dose-response.09-027.Hamblin","volume":"7","author":"YY Huang","year":"2009","unstructured":"Huang YY, Chen AC, Carroll JD, Hamblin MR (2009) Biphasic dose response in low level light therapy. Dose-Response 7:358\u2013383. doi:\n                    10.2203\/dose-response.09-027.Hamblin","journal-title":"Dose-Response"},{"key":"1280_CR15","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1089\/pho.2005.23.470","volume":"23","author":"ACB Salate","year":"2005","unstructured":"Salate ACB, Barbosa G, Gaspar P, Koeke PU, Parizotto NA, Benze BG, Foschiani D (2005) Effect of In-Ga-Al-P diode laser irradiation on angiogenesis in partial ruptures of Achilles tendon in rats. Photomed Laser Surg 23:470\u2013475. doi:\n                    10.1089\/pho.2005.23.470","journal-title":"Photomed Laser Surg"},{"issue":"6","key":"1280_CR16","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1089\/pho.2006.24.754","volume":"24","author":"PM Carrinho","year":"2006","unstructured":"Carrinho PM, Renno ACM, Koeke P, Salate ACB, Parizotto NA, Vidal BC (2006) Comparative study using 685-nm and 830-nm lasers in the tissue repair of tenotomized tendons in mouse. Photomed Laser Surg 24(6):754\u2013758. doi:\n                    10.1089\/pho.2006.24.754","journal-title":"Photomed Laser Surg"},{"issue":"4","key":"1280_CR17","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1002\/lsm.20225","volume":"37","author":"LI Fillipin","year":"2005","unstructured":"Fillipin LI, Mauriz JL, Vedovelli K, Moreira AJ, Zettler CG, Lech O, Marroni NP, Gonz\u00e1lez-Gallego J (2005) Low-level laser therapy (LLLT) prevents oxidative stress and reduces fibrosis in rat traumatized Achilles tendon. Lasers Surg Med 37(4):293\u2013300. doi:\n                    10.1002\/lsm.20225","journal-title":"Lasers Surg Med"},{"key":"1280_CR18","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1002\/lsm.20896","volume":"42","author":"M Xavier","year":"2010","unstructured":"Xavier M, David DR, de Souza RA, Arrieiro AN, Miranda H, Santana ET, Silva JA Jr, Salgado MAC, Aimbire F, Albertini R (2010) Anti-inflammatory effects of low-level light emitting diode therapy on Achilles tendinitis in rats. Lasers Surg Med 42:553\u2013558. doi:\n                    10.1002\/lsm.20896","journal-title":"Lasers Surg Med"},{"key":"1280_CR19","doi-asserted-by":"publisher","first-page":"22","DOI":"10.5978\/islsm.12.22","volume":"12","author":"CS Enwemeka","year":"2000","unstructured":"Enwemeka CS, Reddy GK (2000) The biological effects of laser therapy and other physical modalities on connective tissue repair processes. Laser Ther 12:22\u201330. doi:\n                    10.5978\/islsm.12.22","journal-title":"Laser Ther"},{"key":"1280_CR20","doi-asserted-by":"publisher","unstructured":"Laraia EM, Silva IS, Pereira DM, Dos Reis FA, Albertini R, de Almeida P, Leal Junior EC, de Tarso Camillo de Carvalho P (2012) Effect of low-level laser therapy (660\u00a0nm) on acute inflammation induced by tenotomy of Achilles tendon in rats. Photochem Photobiol 21. doi:\n                    10.1111\/j.1751-1097.2012.01179.x","DOI":"10.1111\/j.1751-1097.2012.01179.x"},{"key":"1280_CR21","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1002\/lsm.21053","volume":"43","author":"F Mafra de Lima","year":"2011","unstructured":"Mafra de Lima F, Villaverde AB, Albertini R, Corr\u00eaa JC, Carvalho RLP, Munin E, Ara\u00fajo T, Silva JA, Aimbire F (2011) Dual effect of low-level laser therapy (LLLT) on the acute lung inflammation induced by intestinal ischemia and reperfusion: action on anti-and pro-inflammatory cytokines. Lasers Surg Med 43:410\u2013420. doi:\n                    10.1002\/lsm.21053","journal-title":"Lasers Surg Med"},{"key":"1280_CR22","doi-asserted-by":"publisher","first-page":"1843","DOI":"10.1016\/j.jhsa.2008.07.020","volume":"33A","author":"ET Ricchetti","year":"2008","unstructured":"Ricchetti ET, Reddy SC, Ansorge HL, Zgonis MH, VanKleunen JP, Liechty KW, Soslowsky LJ, Beredjiklian PK (2008) Effect of interleukin-10 overexpression on the properties of healing tendon in a murine patellar tendon model. J Hand Surg 33A:1843\u20131852. doi:\n                    10.1016\/j.jhsa.2008.07.020","journal-title":"J Hand Surg"},{"key":"1280_CR23","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1177\/03635465000280040901","volume":"28","author":"N Maffulli","year":"2000","unstructured":"Maffulli N, Ewen SW, Waterston SW, Reaper J, Barrass V (2000) Tenocytes from ruptured and tendinopathic Achilles tendons produce greater quantities of type III collagen than tenocytes from normal Achilles tendons. An in vitro model of human tendon healing. Am J Sports Med 28:499\u2013505","journal-title":"Am J Sports Med"},{"key":"1280_CR24","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1002\/lsm.10083","volume":"31","author":"D Fung","year":"2002","unstructured":"Fung D, Ng G, Leung M, Tay D (2002) Therapeutic low energy laser improves the mechanical strength of repairing medial collateral ligament. Lasers Surg Med 31:91\u201396","journal-title":"Lasers Surg Med"},{"issue":"4","key":"1280_CR25","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1002\/lsm.10161","volume":"32","author":"D Fung","year":"2003","unstructured":"Fung D, Ng G, Leung M, Tay D (2003) Effects of a therapeutic laser on the ultrastructural morphology of repairing medial collateral ligament in a rat model. Lasers Surg Med 32(4):286\u2013293. doi:\n                    10.1002\/lsm.10161","journal-title":"Lasers Surg Med"},{"key":"1280_CR26","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1007\/s10103-011-0925-y","volume":"27","author":"J Joensen","year":"2012","unstructured":"Joensen J, Gjerdet NR, Hummelsund S, Iversen V, Lopes-Martins RA, Bjordal JM (2012) An experimental study of low-level laser therapy in rat Achilles tendon injury. Lasers Med Sci 27:103\u2013111. doi:\n                    10.1007\/s10103-011-0925-y","journal-title":"Lasers Med Sci"},{"key":"1280_CR27","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/S0736-0266(00)00012-7","volume":"19","author":"H Sakai","year":"2001","unstructured":"Sakai H, Koibuchi N, Ohtake H, Tamai K, Fukui N, Oda H, Saotome K (2001) Type I and type III procollagen gene expressions in the early phase of ligament healing in rabbits: an in situ hybridization study. J Orthop Res 19:132\u2013135. doi:\n                    10.1016\/S0736-0266(00)00012-7","journal-title":"J Orthop Res"},{"key":"1280_CR28","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/j.arthro.2010.07.012","volume":"27","author":"K Otoshi","year":"2011","unstructured":"Otoshi K, Kikuchi S, Ohi G, Numazaki H, Sekiguchi M, Konno S (2011) The process of tendon regeneration in an Achilles tendon resection rat model as a model for hamstring regeneration after harvesting for anterior cruciate ligament reconstruction. Arthroscopy 27:218\u2013227. doi:\n                    10.1016\/j.arthro.2010.07.012","journal-title":"Arthroscopy"},{"key":"1280_CR29","doi-asserted-by":"publisher","first-page":"1925","DOI":"10.1134\/S1054660X09170022","volume":"19","author":"JLN Bastos","year":"2009","unstructured":"Bastos JLN, Lizarelli RFZ, Parizotto NA (2009) Comparative study of laser and LED systems of low intensity applied to tendon healing. Laser Phys 19:1925\u20131931. doi:\n                    10.1134\/S1054660X09170022","journal-title":"Laser Phys"},{"key":"1280_CR30","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1089\/pho.2010.2919","volume":"29","author":"MA Neves","year":"2011","unstructured":"Neves MA, Pinfildi CE, Wood VT, Gobbato RC, da Silva FM, Parizottro NA, Hochman B, Ferreira LM (2011) Different power settings of LLLT on the repair of the calcaneal tendon. Photomed Laser Surg 29:663\u2013668. doi:\n                    10.1089\/pho.2010.2919","journal-title":"Photomed Laser Surg"},{"key":"1280_CR31","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1002\/lsm.20932","volume":"42","author":"VT Wood","year":"2010","unstructured":"Wood VT, Pinfildi CE, Neves MA, Parizoto NA, Hochman B, Ferreira LM (2010) Collagen changes and realignment induced by low-level laser therapy and low-intensity ultrasound in the calcaneal tendon. Lasers Surg Med 42:559\u2013565. doi:\n                    10.1002\/lsm.20932","journal-title":"Lasers Surg Med"},{"key":"1280_CR32","doi-asserted-by":"publisher","unstructured":"Casalechi HL, Leal-Junior EC, Xavier M, Silva JA Jr, de Carvalho PD, Aimbire F, Albertini R (2013) Low-level laser therapy in experimental model of collagenase-induced tendinitis in rats: effects in acute and chronic inflammatory phases. Lasers Med Sci. doi: \n                    10.1007\/s10103-012-1189-x","DOI":"10.1007\/s10103-012-1189-x"}],"container-title":["Lasers in Medical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-013-1280-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10103-013-1280-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-013-1280-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-013-1280-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T16:37:54Z","timestamp":1581957474000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10103-013-1280-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,13]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["1280"],"URL":"https:\/\/doi.org\/10.1007\/s10103-013-1280-y","relation":{},"ISSN":["0268-8921","1435-604X"],"issn-type":[{"value":"0268-8921","type":"print"},{"value":"1435-604X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,13]]}}}