{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T15:54:55Z","timestamp":1778774095883,"version":"3.51.4"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,5,10]],"date-time":"2013-05-10T00:00:00Z","timestamp":1368144000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1007\/s10103-013-1337-y","type":"journal-article","created":{"date-parts":[[2013,5,9]],"date-time":"2013-05-09T00:17:57Z","timestamp":1368058677000},"page":"27-34","source":"Crossref","is-referenced-by-count":81,"title":["Single or repeated antimicrobial photodynamic therapy as adjunct to ultrasonic debridement in residual periodontal pockets: clinical, microbiological, and local biological effects"],"prefix":"10.1007","volume":"30","author":[{"given":"V\u00e9ronique S.","family":"M\u00fcller Campanile","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Giannopoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaetano","family":"Campanile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 A.","family":"Cancela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Mombelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,5,10]]},"reference":[{"key":"1337_CR1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1034\/j.1600-051x.2001.280102.x","volume":"28","author":"T Kocher","year":"2001","unstructured":"Kocher T, Fanghanel J, Sawaf H, Litz R (2001) Substance loss caused by scaling with different sonic scaler inserts\u2014an in vitro study. J Clin Periodontol 28:9\u201315","journal-title":"J Clin Periodontol"},{"key":"1337_CR2","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/j.1600-051X.1998.tb02422.x","volume":"25","author":"TF Flemmig","year":"1998","unstructured":"Flemmig TF, Petersilka GJ, Mehl A, Hickel R, Klaiber B (1998) The effect of working parameters on root substance removal using a piezoelectric ultrasonic scaler in vitro. J Clin Periodontol 25:158\u2013163","journal-title":"J Clin Periodontol"},{"key":"1337_CR3","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1600-051X.1991.tb00104.x","volume":"18","author":"L Ritz","year":"1991","unstructured":"Ritz L, Hefti AF, Rateitschak KH (1991) An in vitro investigation on the loss of root substance in scaling with various instruments. J Clin Periodontol 18:643\u2013647","journal-title":"J Clin Periodontol"},{"key":"1337_CR4","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1902\/jop.1991.62.12.750","volume":"62","author":"U Zappa","year":"1991","unstructured":"Zappa U, Smith B, Simona C, Graf H, Case D, Kim W (1991) Root substance removal by scaling and root planing. J Periodontol 62:750\u2013754","journal-title":"J Periodontol"},{"key":"1337_CR5","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1600-051X.1981.tb02024.x","volume":"8","author":"A Badersten","year":"1981","unstructured":"Badersten A, Nilv\u00e9us R, Egelberg J (1981) Effect of nonsurgical periodontal therapy. I. Moderately advanced periodontitis. J Clin Periodontol 8:57\u201372","journal-title":"J Clin Periodontol"},{"key":"1337_CR6","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/j.1600-051X.1984.tb01309.x","volume":"11","author":"A Badersten","year":"1984","unstructured":"Badersten A, Nilv\u00e9us R, Egelberg J (1984) Effect of nonsurgical periodontal therapy. II. Severely advanced periodontitis. J Clin Periodontol 11:63\u201376","journal-title":"J Clin Periodontol"},{"issue":"Suppl 3","key":"1337_CR7","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1034\/j.1600-051X.29.s3.10.x","volume":"29","author":"B Troil von","year":"2002","unstructured":"von Troil B, Needleman I, Sanz M (2002) A systematic review of the prevalence of root sensitivity following periodontal therapy. J Clin Periodontol 29(Suppl 3):173\u2013177","journal-title":"J Clin Periodontol"},{"key":"1337_CR8","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/j.1399-302X.1993.tb00663.x","volume":"8","author":"M Wilson","year":"1993","unstructured":"Wilson M, Dobson J, Sarkar S (1993) Sensitization of periodontopathogenic bacteria to killing by light from a low-power laser. Oral Microbiol Immunol 8:182\u2013187","journal-title":"Oral Microbiol Immunol"},{"key":"1337_CR9","first-page":"181","volume":"44","author":"M Wilson","year":"1994","unstructured":"Wilson M (1994) Bactericidal effect of laser light and its potential use in the treatment of plaque-related diseases. Int Dent J 44:181\u2013189","journal-title":"Int Dent J"},{"key":"1337_CR10","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1128\/AAC.47.3.932-940.2003","volume":"47","author":"N K\u00f6merik","year":"2003","unstructured":"K\u00f6merik N, Nakanishi H, MacRobert AJ, Henderson B, Speight P, Wilson M (2003) In vivo killing of Porphyromonas gingivalis by toluidine blue-mediated photosensitization in an animal model. Antimicrob Agents Chemother 47:932\u2013940","journal-title":"Antimicrob Agents Chemother"},{"key":"1337_CR11","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1902\/jop.2009.090285","volume":"81","author":"A Azarpazhooh","year":"2010","unstructured":"Azarpazhooh A, Shah PS, Tenenbaum HC, Goldberg MB (2010) The effect of photodynamic therapy for periodontitis: a systematic review and meta-analysis. J Periodontol 81:4\u201314","journal-title":"J Periodontol"},{"key":"1337_CR12","doi-asserted-by":"crossref","unstructured":"Sgolastra F, Petrucci A, Gatto R, Marzo G, Monaco A (2013) Photodynamic therapy in the treatment of chronic periodontitis: a systematic review and meta-analysis. Lasers Med Sci 28:669\u2013682","DOI":"10.1007\/s10103-011-1002-2"},{"key":"1337_CR13","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s10103-009-0744-6","volume":"25","author":"MA Atieh","year":"2010","unstructured":"Atieh MA (2010) Photodynamic therapy as an adjunctive treatment for chronic periodontitis: a meta-analysis. Lasers Med Sci 25:605\u2013613","journal-title":"Lasers Med Sci"},{"key":"1337_CR14","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1111\/j.1600-051X.2009.01432.x","volume":"36","author":"M Lulic","year":"2009","unstructured":"Lulic M, Leiggener Gorog I, Salvi GE, Ramseier CA, Mattheos N, Lang NP (2009) One-year outcomes of repeated adjunctive photodynamic therapy during periodontal maintenance: a proof-of-principle randomized-controlled clinical trial. J Clin Periodontol 36:661\u2013666","journal-title":"J Clin Periodontol"},{"key":"1337_CR15","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1002\/lsm.10010","volume":"30","author":"S Yilmaz","year":"2002","unstructured":"Yilmaz S, Kuru B, Kuru L, Noyan U, Argun D, Kadir T (2002) Effect of gallium arsenide diode laser on human periodontal disease: a microbiological and clinical study. Lasers Surg Med 30:60\u201366","journal-title":"Lasers Surg Med"},{"key":"1337_CR16","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1902\/jop.2011.110281","volume":"83","author":"C Giannopoulou","year":"2012","unstructured":"Giannopoulou C, Cappuyns I, Cancela J, Cionca N, Mombelli A (2012) Effect of photodynamic therapy, diode laser and deep scaling on cytokine and acute-phase protein levels in gingival crevicular fluid of residual periodontal pockets. J Periodontol 83:1018\u20131027","journal-title":"J Periodontol"},{"key":"1337_CR17","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1902\/jop.2009.070465","volume":"80","author":"RR Oliveira de","year":"2009","unstructured":"de Oliveira RR, Schwartz-Filho HO, Novaes AB, Garlet GP, de Souza RF, Taba M, Scombatti de Souza SL, Ribeiro FJ (2009) Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: cytokine profile in gingival crevicular fluid, preliminary results. J Periodontol 80:98\u2013105","journal-title":"J Periodontol"},{"key":"1337_CR18","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1902\/annals.2003.8.1.115","volume":"8","author":"AD Haffajee","year":"2003","unstructured":"Haffajee AD, Socransky SS, Gunsolley JC (2003) Systemic anti-infective periodontal therapy: a systematic review. Ann Periodontol 8:115\u2013181","journal-title":"Ann Periodontol"},{"key":"1337_CR19","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1034\/j.1600-051X.29.s3.8.x","volume":"29","author":"D Herrera","year":"2002","unstructured":"Herrera D, Sanz M, Jepsen S, Needleman I, Rold\u00e1n S (2002) A systematic review on the effect of systemic antimicrobials as an adjunct to scaling and root planing in periodontitis patients. J Clin Periodontol 29:136\u2013159","journal-title":"J Clin Periodontol"},{"key":"1337_CR20","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3109\/00016356408993968","volume":"22","author":"J Silness","year":"1964","unstructured":"Silness J, L\u00f6e H (1964) Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 22:121\u2013135","journal-title":"Acta Odontol Scand"},{"key":"1337_CR21","doi-asserted-by":"crossref","first-page":"533","DOI":"10.3109\/00016356309011240","volume":"21","author":"H L\u00f6e","year":"1963","unstructured":"L\u00f6e H, Silness J (1963) Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 21:533\u2013551","journal-title":"Acta Odontol Scand"},{"key":"1337_CR22","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.micinf.2005.09.004","volume":"8","author":"E Kozarov","year":"2006","unstructured":"Kozarov E, Sweier D, Shelburne C, Progulske-Fox A, Lopatin D (2006) Detection of bacterial DNA in atheromatous plaques by quantitative PCR. Microbes Infect 8:687\u2013693","journal-title":"Microbes Infect"},{"key":"1337_CR23","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0167-7012(99)00106-2","volume":"39","author":"CE Shelburne","year":"2000","unstructured":"Shelburne CE, Prabhu A, Gleason RM, Mullally BH, Coulter WA (2000) Quantitation of Bacteroides forsythus in subgingival plaque comparison of immunoassay and quantitative polymerase chain reaction. J Microbiol Methods 39:97\u2013107","journal-title":"J Microbiol Methods"},{"key":"1337_CR24","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1902\/jop.2008.070652","volume":"79","author":"N Christodoulides","year":"2008","unstructured":"Christodoulides N, Nikolidakis D, Chondros P, Becker J, Schwarz F, Rossler R, Sculean A (2008) Photodynamic therapy as an adjunct to non-surgical periodontal treatment: a randomized, controlled clinical trial. J Periodontol 79:1638\u20131644","journal-title":"J Periodontol"},{"key":"1337_CR25","first-page":"34","volume":"18","author":"R Andersen","year":"2007","unstructured":"Andersen R, Loebel N, Hammond D, Wilson M (2007) Treatment of periodontal disease by photodisinfection compared to scaling and root planing. J Clin Dent 18:34\u201338","journal-title":"J Clin Dent"},{"key":"1337_CR26","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1111\/j.1600-051X.2008.01303.x","volume":"35","author":"A Braun","year":"2008","unstructured":"Braun A, Dehn C, Krause F, Jepsen S (2008) Short-term clinical effects of adjunctive antimicrobial photodynamic therapy in periodontal treatment: a randomized clinical trial. J Clin Periodontol 35:877\u2013884","journal-title":"J Clin Periodontol"},{"key":"1337_CR27","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1089\/pho.2009.2727","volume":"29","author":"L Ge","year":"2011","unstructured":"Ge L, Shu R, Li Y, Li C, Luo L, Song Z, Xie Y, Liu D (2011) Adjunctive effect of photodynamic therapy to scaling and root planing in the treatment of chronic periodontitis. Photomed Laser Surg 29:33\u201337","journal-title":"Photomed Laser Surg"},{"key":"1337_CR28","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jphotobiol.2004.11.023","volume":"79","author":"P Meisel","year":"2005","unstructured":"Meisel P, Kocher T (2005) Photodynamic therapy for periodontal diseases: state of the art. J Photochem Photobiol B 79:159\u2013170","journal-title":"J Photochem Photobiol B"},{"key":"1337_CR29","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1902\/jop.2007.060494","volume":"78","author":"RR Oliveira de","year":"2007","unstructured":"de Oliveira RR, Schwartz-Filho HO, Novaes AB Jr, Taba M Jr (2007) Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: a preliminary randomized controlled clinical study. J Periodontol 78:965\u2013973","journal-title":"J Periodontol"},{"key":"1337_CR30","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1007\/s10103-011-1027-6","volume":"27","author":"I Cappuyns","year":"2012","unstructured":"Cappuyns I, Cionca N, Wick P, Giannopoulou C, Mombelli A (2012) Treatment of residual pockets with photodynamic therapy, diode laser, or deep scaling: a randomized, split-mouth controlled clinical trial. Lasers Med Sci 27:979\u2013986","journal-title":"Lasers Med Sci"},{"key":"1337_CR31","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s00784-009-0347-4","volume":"14","author":"A R\u00fchling","year":"2010","unstructured":"R\u00fchling A, Fangh\u00e4nel J, Houshmand M, Kuhr A, Meisel P, Schwahn C, Kocher T (2010) Photodynamic therapy of persistent pockets in maintenance patients\u2014a clinical study. Clin Oral Investig 14:637\u2013644","journal-title":"Clin Oral Investig"},{"key":"1337_CR32","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1600-051X.2009.01412.x","volume":"36","author":"R Polansky","year":"2009","unstructured":"Polansky R, Haas M, Heschl A, Wimmer G (2009) Clinical effectiveness of photodynamic therapy in the treatment of periodontitis. J Clin Periodontol 36:575\u2013580","journal-title":"J Clin Periodontol"},{"key":"1337_CR33","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1007\/s10103-008-0565-z","volume":"24","author":"P Chondros","year":"2009","unstructured":"Chondros P, Nikolidakis D, Christodoulides N, Rossler R, Gutknecht N, Sculean A (2009) Photodynamic therapy as adjunct to non-surgical periodontal treatment in patients on periodontal maintenance: a randomized controlled clinical trial. Lasers Med Sci 24:681\u2013688","journal-title":"Lasers Med Sci"},{"key":"1337_CR34","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1600-0765.2010.01316.x","volume":"46","author":"J Lui","year":"2011","unstructured":"Lui J, Corbet EF, Jin L (2011) Combined photodynamic and low-level laser therapies as an adjunct to nonsurgical treatment of chronic periodontitis. J Periodontal Res 46:89\u201396","journal-title":"J Periodontal Res"},{"key":"1337_CR35","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1111\/j.1600-051X.2010.01603.x","volume":"37","author":"E Megson","year":"2010","unstructured":"Megson E, Fitzsimmons T, Dharmapatni K, Bartold PM (2010) C-reactive protein in gingival crevicular fluid may be indicative of systemic inflammation. J Clin Periodontol 37:797\u2013804","journal-title":"J Clin Periodontol"},{"key":"1337_CR36","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1600-051X.2010.01694.x","volume":"38","author":"HG Yilmaz","year":"2011","unstructured":"Yilmaz HG, Cengiz E, Kurtulmus-Yilmaz S, Leblebicioglu B (2011) Effectiveness of Er, Cr:YSGG laser on dentine hypersensitivity: a controlled clinical trial. J Clin Periodontol 38:341\u2013346","journal-title":"J Clin Periodontol"}],"container-title":["Lasers in Medical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-013-1337-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10103-013-1337-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-013-1337-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,26]],"date-time":"2019-03-26T18:52:21Z","timestamp":1553626341000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10103-013-1337-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,10]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["1337"],"URL":"https:\/\/doi.org\/10.1007\/s10103-013-1337-y","relation":{},"ISSN":["0268-8921","1435-604X"],"issn-type":[{"value":"0268-8921","type":"print"},{"value":"1435-604X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,10]]}}}