{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T21:35:17Z","timestamp":1757453717931,"version":"3.37.3"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T00:00:00Z","timestamp":1593734400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T00:00:00Z","timestamp":1593734400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1007\/s10103-020-03087-y","type":"journal-article","created":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T08:03:51Z","timestamp":1593763431000},"page":"413-420","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Histopathological and biomechanical changes in soft palate in response to non-ablative 9.3-\u03bcm CO2 laser irradiation: an in vivo study"],"prefix":"10.1007","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6219-5144","authenticated-orcid":false,"given":"Ali H.","family":"Badreddine","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Couitt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Kerbage","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,3]]},"reference":[{"issue":"1","key":"3087_CR1","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1002\/lsm.10006","volume":"30","author":"Z Wang","year":"2002","unstructured":"Wang Z, Rebeiz EE, Shapshay SM (2002) Laser soft palate stiffening: an alternative to uvulopalatopharyngoplasty. Lasers Surg Med 30(1):40\u201343 http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11857602. Accessed February 20, 2019","journal-title":"Lasers Surg Med"},{"issue":"10","key":"3087_CR2","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1001\/archderm.134.10.1255","volume":"134","author":"KM Kirsch","year":"1998","unstructured":"Kirsch KM, Zelickson BD, Zachary CB, Tope WD (1998) Ultrastructure of collagen thermally denatured by microsecond domain pulsed carbon dioxide laser. Arch Dermatol 134(10):1255\u20131259. https:\/\/doi.org\/10.1001\/archderm.134.10.1255","journal-title":"Arch Dermatol"},{"issue":"5","key":"3087_CR3","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1002\/1096-9101(2000)27:5<395::AID-LSM1000>3.0.CO;2-4","volume":"27","author":"RE Fitzpatrick","year":"2000","unstructured":"Fitzpatrick RE, Rostan EF, Marchell N (2000) Collagen tightening induced by carbon dioxide laser versus erbium: YAG laser. Lasers Surg Med 27(5):395\u2013403. https:\/\/doi.org\/10.1002\/1096-9101(2000)27:5<395::AID-LSM1000>3.0.CO;2-4","journal-title":"Lasers Surg Med"},{"issue":"4","key":"3087_CR4","doi-asserted-by":"publisher","first-page":"285","DOI":"10.5935\/scd1984-8773.2015741","volume":"7","author":"MG da Cunha","year":"2015","unstructured":"da Cunha MG, Paravic FD, Machado CA (2015) Histological changes of collagen types after different modalities of dermal remodeling treatment: a literature review. Surg Cosmet Dermatol 7(4):285\u2013291. https:\/\/doi.org\/10.5935\/scd1984-8773.2015741","journal-title":"Surg Cosmet Dermatol"},{"issue":"11","key":"3087_CR5","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1046\/j.1524-4725.1999.99091.x","volume":"25","author":"EV Ross","year":"1999","unstructured":"Ross EV, Yashar SS, Naseef GS et al (1999) A pilot study of in vivo immediate tissue contraction with CO2 skin laser resurfacing in a live farm pig. Dermatologic Surg 25(11):851\u2013856. https:\/\/doi.org\/10.1046\/j.1524-4725.1999.99091.x","journal-title":"Dermatologic Surg"},{"key":"3087_CR6","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/3-540-30020-1_20","volume-title":"Cleft Lip and Palate","author":"JW Von Den Hoff","year":"2006","unstructured":"Von Den Hoff JW, Maltha JC, Kuijpers-Jagtman AM (2006) Palatal wound healing: the effects of scarring on growth. In: Cleft Lip and Palate. Springer Berlin Heidelberg, Berlin, pp 301\u2013313. https:\/\/doi.org\/10.1007\/3-540-30020-1_20"},{"issue":"1","key":"3087_CR7","first-page":"36","volume":"1","author":"ZV Krysztof Miracki","year":"2013","unstructured":"Krysztof Miracki ZV (2013) Nonsurgical minimally invasive Er:YAG laser snoring treatment. J Laser Heal Acad 1(1):36\u201341","journal-title":"J Laser Heal Acad"},{"issue":"1","key":"3087_CR8","first-page":"S06","volume":"2015","author":"J Sippus","year":"2015","unstructured":"Sippus J (2015) NightLase procedure \u2013 laser snoring and sleep apnea reduction treatment. J Laser Heal Acad 2015(1):S06","journal-title":"J Laser Heal Acad"},{"issue":"2","key":"3087_CR9","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1159\/000443510","volume":"78","author":"EA Cetinkaya","year":"2016","unstructured":"Cetinkaya EA, Turker M, Kiraz K, Gulkesen HK (2016) Er: Yag laser treatment of simple snorers in an outpatient setting. Orl. 78(2):70\u201376. https:\/\/doi.org\/10.1159\/000443510","journal-title":"Orl."},{"issue":"3","key":"3087_CR10","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.cden.2011.02.017","volume":"55","author":"J Green","year":"2011","unstructured":"Green J, Weiss A, Stern A (2011) Lasers and radiofrequency devices in dentistry. Dent Clin N Am 55(3):585\u2013597. https:\/\/doi.org\/10.1016\/j.cden.2011.02.017","journal-title":"Dent Clin N Am"},{"issue":"11","key":"3087_CR11","first-page":"10","volume":"2222","author":"D Fantarella","year":"2014","unstructured":"Fantarella D, Kotlow L (2014) The 9.3-\u03bcm CO 2 dental laser: technical development and early clinical experiences. J Laser Dent J Laser Dent 2222(11):10\u201327","journal-title":"J Laser Dent J Laser Dent"},{"issue":"7","key":"3087_CR12","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1001\/archotol.125.7.786","volume":"125","author":"G Berger","year":"1999","unstructured":"Berger G, Finltelsteln Y, Oplnr D (1999) Histopathologic changes of the soft palate after laser-assisted uvulopalatoplasty. Arch Otolaryngol Head Neck Surg 125(7):786\u2013790. https:\/\/doi.org\/10.1001\/archotol.125.7.786","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"4","key":"3087_CR13","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1001\/archotol.127.4.412","volume":"127","author":"G Berger","year":"2001","unstructured":"Berger G, Finkelstein Y, Stein G, Ophir D (2001) Laser-assisted uvulopalatoplasty for snoring: medium- to long-term subjective and objective analysis. Arch Otolaryngol Head Neck Surg 127(4):412\u2013417. https:\/\/doi.org\/10.1001\/archotol.127.4.412","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"2","key":"3087_CR14","doi-asserted-by":"publisher","first-page":"279","DOI":"10.5272\/jimab.2013192.279","volume":"19","author":"H Lalabonova","year":"2013","unstructured":"Lalabonova H, Ilieva EM (2013) Clinical evaluation of the healing process of oral soft tissue surgical wounds stimulated by low-level laser therapy. J IMAB - Annu Proceeding 19(2):279\u2013281. https:\/\/doi.org\/10.5272\/jimab.2013192.279","journal-title":"J IMAB - Annu Proceeding"},{"issue":"4","key":"3087_CR15","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/j.otohns.2006.05.008","volume":"135","author":"E Poyrazo\u01e7lu","year":"2006","unstructured":"Poyrazo\u01e7lu E, Do\u01e7ru S, Saat B, G\u00fcng\u00f6r A, \u00c7ekin E, Cincik H (2006) Histologic effects of injection snoreplasty and radiofrequency in the rat soft palate. Otolaryngol Head Neck Surg 135(4):561\u2013564. https:\/\/doi.org\/10.1016\/j.otohns.2006.05.008","journal-title":"Otolaryngol Head Neck Surg"},{"key":"3087_CR16","volume-title":"Biomechanics: mechanical properties of living tissues","author":"Y Fung","year":"2013","unstructured":"Fung Y (2013) Biomechanics: mechanical properties of living tissues. Springer Science & Business Media, New York"},{"key":"3087_CR17","doi-asserted-by":"publisher","unstructured":"Song AS, Najjar AM, Diller KR (2014) Thermally induced apoptosis, necrosis, and heat shock protein expression in 3D culture. https:\/\/doi.org\/10.1115\/1.4027272","DOI":"10.1115\/1.4027272"},{"issue":"03","key":"3087_CR18","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1557\/jmr.2009.0130","volume":"24","author":"R Akhtar","year":"2009","unstructured":"Akhtar R, Schwarzer N, Sherratt MJ et al (2009) Nanoindentation of histological specimens: mapping the elastic properties of soft tissues. J Mater Res 24(03):638\u2013646. https:\/\/doi.org\/10.1557\/jmr.2009.0130","journal-title":"J Mater Res"},{"issue":"12","key":"3087_CR19","doi-asserted-by":"publisher","first-page":"654","DOI":"10.3390\/mi9120654","volume":"9","author":"L Qian","year":"2018","unstructured":"Qian L, Zhao H (2018) Nanoindentation of soft biological materials. Micromachines. 9(12):654. https:\/\/doi.org\/10.3390\/mi9120654","journal-title":"Micromachines."},{"issue":"3","key":"3087_CR20","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1089\/ten.TEB.2010.0520","volume":"17","author":"CT McKee","year":"2011","unstructured":"McKee CT, Last JA, Russell P, Murphy CJ (2011) Indentation versus tensile measurements of Young\u2019s modulus for soft biological tissues. Tissue Eng Part B Rev 17(3):155\u2013164. https:\/\/doi.org\/10.1089\/ten.TEB.2010.0520","journal-title":"Tissue Eng Part B Rev"},{"issue":"3","key":"3087_CR21","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1097\/00006534-199809030-00040","volume":"102","author":"BR Seckel","year":"1998","unstructured":"Seckel BR, Younai S, Wang KK (1998) Skin tightening effects of the ultrapulse CO2 laser. Plast Reconstr Surg 102(3):872\u2013877. https:\/\/doi.org\/10.1097\/00006534-199809030-00040","journal-title":"Plast Reconstr Surg"},{"issue":"2","key":"3087_CR22","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1177\/1090820X10369373","volume":"30","author":"GH Sasaki","year":"2010","unstructured":"Sasaki GH (2010) Quantification of human abdominal tissue tightening and contraction after component treatments with 1064-nm\/1320-nm laser-assisted lipolysis: clinical implications. Aesthetic Surg J 30(2):239\u2013245. https:\/\/doi.org\/10.1177\/1090820X10369373","journal-title":"Aesthetic Surg J"},{"key":"3087_CR23","unstructured":"Svahnstr\u00f6m K (2013) Er : YAG laser treatment of sleep-disordered breathing. J laser Health Acad 2013(2):13\u201316"}],"container-title":["Lasers in Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-020-03087-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10103-020-03087-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-020-03087-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,3]],"date-time":"2021-07-03T00:10:45Z","timestamp":1625271045000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10103-020-03087-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,3]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["3087"],"URL":"https:\/\/doi.org\/10.1007\/s10103-020-03087-y","relation":{},"ISSN":["0268-8921","1435-604X"],"issn-type":[{"type":"print","value":"0268-8921"},{"type":"electronic","value":"1435-604X"}],"subject":[],"published":{"date-parts":[[2020,7,3]]},"assertion":[{"value":"6 February 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 June 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study did not unnecessarily duplicate previous testing and that there were no non-animal alternatives acceptable for the evaluation of the test article as defined by the protocol. No evidence of pain and distress was reported to the Veterinarian or Study Director. Toxikon strictly adhered to the following standards in maintaining the animal care and use program:United States Department of Agriculture (USDA), Animal and Plant Health Inspection Service, 9 CFR Ch. 1, Subchapter A-Animal Welfare.\u201cGuide for the Care and Use of Laboratory Animals,\u201d National Research Council, 2011.Office for Laboratory Animal Welfare (OLAW), \u201cPublic Health Service Policy on Humane Care and Use of Laboratory Animals,\u201d Health Research Extension Act of 1985 (Public Law 99\u2013158 November 20, 1985), Revised 2015.ISO 109932, 2006, Biological Evaluation of Medical Devices Part 2: Animal Welfare Requirements.AAALAC International accreditation.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}