{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T16:29:14Z","timestamp":1747153754117,"version":"3.40.5"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T00:00:00Z","timestamp":1602806400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T00:00:00Z","timestamp":1602806400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s10103-020-03162-4","type":"journal-article","created":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T22:02:34Z","timestamp":1602885754000},"page":"1227-1233","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Carbon dioxide (CO2) laser ablation of symptomatic vaginal endometriosis: a pilot study"],"prefix":"10.1007","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1199-1888","authenticated-orcid":false,"given":"Laura","family":"Buggio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ermelinda","family":"Monti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Liverani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7288-0113","authenticated-orcid":false,"given":"Maria Pina","family":"Frattaruolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7813-9684","authenticated-orcid":false,"given":"Dhouha","family":"Dridi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0223-0032","authenticated-orcid":false,"given":"Edgardo","family":"Somigliana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,10,16]]},"reference":[{"key":"3162_CR1","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1038\/nrendo.2013.255","volume":"10","author":"P Vercellini","year":"2014","unstructured":"Vercellini P, Somigliana E, Vigan\u00f2 P, Fedele L (2014) Endometriosis: pathogenesis and treatment. Nat Rev Endocrinol 10:261\u2013275. https:\/\/doi.org\/10.1038\/nrendo.2013.255","journal-title":"Nat Rev Endocrinol"},{"key":"3162_CR2","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1016\/j.esxm.2020.01.002","volume":"8","author":"KJ Wahl","year":"2020","unstructured":"Wahl KJ, Orr NL, Lisonek M, Noga H, Bedaiwy MA, Williams C et al (2020) J Sex Med 8:274\u2013281. https:\/\/doi.org\/10.1016\/j.esxm.2020.01.002","journal-title":"J Sex Med"},{"key":"3162_CR3","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1136\/jfprhc-2012-100530","volume":"40","author":"L Hummelshoj","year":"2014","unstructured":"Hummelshoj L, De Graaff A, Dunselman G, Vercellini P (2014) Let\u2019s talk about sex and endometriosis. J Fam Plann Reprod Health Care 40:8\u201310. https:\/\/doi.org\/10.1136\/jfprhc-2012-100530","journal-title":"J Fam Plann Reprod Health Care"},{"key":"3162_CR4","doi-asserted-by":"publisher","first-page":"2677","DOI":"10.1093\/humrep\/det284","volume":"28","author":"AA De Graaff","year":"2013","unstructured":"De Graaff AA, D\u2019Hooghe TM, Dunselman GA, Dirksen CD, Hummelshoj L, WERF EndoCost Consortium (2013) The significant effect of endometriosis on physical, mental and social wellbeing: results from an international cross-sectional survey. Hum Reprod 28:2677\u20132685. https:\/\/doi.org\/10.1093\/humrep\/det284","journal-title":"Hum Reprod"},{"key":"3162_CR5","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1111\/jsm.12349","volume":"11","author":"A Evangelista","year":"2014","unstructured":"Evangelista A, Dantas T, Zendron C, Soares T, Vaz G, Oliveira MA (2014) Sexual function in patients with deep infiltrating endometriosis. J Sex Med 11:140\u2013145. https:\/\/doi.org\/10.1111\/jsm.12349","journal-title":"J Sex Med"},{"key":"3162_CR6","doi-asserted-by":"publisher","first-page":"1566","DOI":"10.1177\/1933719117707054","volume":"24","author":"G Barbara","year":"2017","unstructured":"Barbara G, Facchin F, Buggio L et al (2017) What is known and unknown about the association between endometriosis and sexual functioning: a systematic review of the literature. Reprod Sci 24:1566\u20131576. https:\/\/doi.org\/10.1177\/1933719117707054","journal-title":"Reprod Sci"},{"key":"3162_CR7","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1016\/j.sxmr.2017.06.005","volume":"5","author":"PJ Yong","year":"2017","unstructured":"Yong PJ (2017) Deep dyspareunia in endometriosis: a proposed framework based on pain mechanisms and genito-pelvic pain penetration disorder. Sex Med Rev 5:495\u2013507. https:\/\/doi.org\/10.1016\/j.sxmr.2017.06.005","journal-title":"Sex Med Rev"},{"key":"3162_CR8","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1055\/s-2008-1068755","volume":"15","author":"P Vercellini","year":"1997","unstructured":"Vercellini P (1997) Endometriosis: what a pain it is. Semin Reprod Endocrinol 15:251\u2013261. https:\/\/doi.org\/10.1055\/s-2008-1068755","journal-title":"Semin Reprod Endocrinol"},{"key":"3162_CR9","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.1016\/j.fertnstert.2012.07.1129","volume":"98","author":"P Vercellini","year":"2012","unstructured":"Vercellini P, Somigliana E, Buggio L, Barbara G, Frattaruolo MP, Fedele L (2012) \u201cI can\u2019t get no satisfaction\u201d: deep dyspareunia and sexual functioning in women with rectovaginal endometriosis. Fertil Steril 98:1503\u201311.e1. https:\/\/doi.org\/10.1016\/j.fertnstert.2012.07.1129","journal-title":"Fertil Steril"},{"key":"3162_CR10","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1177\/1933719110382921","volume":"18","author":"P Vercellini","year":"2011","unstructured":"Vercellini P, Meana M, Hummelshoj L, Somigliana E, Vigan\u00f2 P, Fedele L (2011) Priorities for endometriosis research: a proposed focus on deep dyspareunia. Reprod Sci 18:114\u2013118. https:\/\/doi.org\/10.1177\/1933719110382921","journal-title":"Reprod Sci"},{"key":"3162_CR11","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1016\/j.fertnstert.2016.10.022","volume":"106","author":"P Vercellini","year":"2016","unstructured":"Vercellini P, Buggio L, Berlanda N, Barbara G, Somigliana E, Bosari S (2016) Estrogen-progestins and progestins for the management of endometriosis. Fertil Steril 106:1552\u20131571.e2. https:\/\/doi.org\/10.1016\/j.fertnstert.2016.10.022","journal-title":"Fertil Steril"},{"key":"3162_CR12","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1093\/humupd\/dmw031","volume":"22","author":"N Pluchino","year":"2016","unstructured":"Pluchino N, Wenger JM, Petignat P et al (2016) Sexual function in endometriosis patients and their partners: effect of the disease and consequences of treatment. Hum Reprod Update 22:762\u2013774. https:\/\/doi.org\/10.1093\/humupd\/dmw031","journal-title":"Hum Reprod Update"},{"key":"3162_CR13","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/s1074-3804(05)60549-x","volume":"8","author":"V Anaf","year":"2001","unstructured":"Anaf V, Simon P, El Nakadi I, Simonart T, Noel JC, Buxant F (2001) Impact of surgical resection of rectovaginal pouch of Douglas endometriotic nodules on pelvic pain and some elements of patients\u2019 sex life. J Am Assoc Gynecol Laparosc 8:55\u201360. https:\/\/doi.org\/10.1016\/s1074-3804(05)60549-x","journal-title":"J Am Assoc Gynecol Laparosc"},{"key":"3162_CR14","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1016\/j.ajog.2006.03.068","volume":"195","author":"P Vercellini","year":"2006","unstructured":"Vercellini P, Pietropaolo G, De Giorgi O, Daguati R, Pasin R, Crosignani PG (2006) Reproductive performance in infertile women with rectovaginal endometriosis: is surgery worthwhile? Am J Obstet Gynecol 195:1303\u20131310. https:\/\/doi.org\/10.1016\/j.ajog.2006.03.068","journal-title":"Am J Obstet Gynecol"},{"key":"3162_CR15","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1093\/humrep\/del465","volume":"22","author":"S Ferrero","year":"2007","unstructured":"Ferrero S, Abbamonte LH, Giordano M, Ragni N, Remorgida V (2007) Deep dyspareunia and sex life after laparoscopic excision of endometriosis. Hum Reprod 22:1142\u20131148. https:\/\/doi.org\/10.1093\/humrep\/del465","journal-title":"Hum Reprod"},{"key":"3162_CR16","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1093\/humupd\/dmn062","volume":"15","author":"P Vercellini","year":"2009","unstructured":"Vercellini P, Crosignani PG, Abbiati A, Somigliana E, Vigan\u00f2 FL (2009) The effect of surgery for symptomatic endometriosis: the other side of the story. Hum Reprod Update 15:177\u2013188. https:\/\/doi.org\/10.1093\/humupd\/dmn062","journal-title":"Hum Reprod Update"},{"key":"3162_CR17","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1111\/j.1471-0528.2010.02744.x","volume":"118","author":"C De Cicco","year":"2011","unstructured":"De Cicco C, Corona R, Schonman R, Mailova K, Ussia A, Koninckx P (2011) Bowel resection for deep endometriosis: a systematic review. BJOG 118:285\u2013291. https:\/\/doi.org\/10.1111\/j.1471-0528.2010.02744.x","journal-title":"BJOG"},{"key":"3162_CR18","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1111\/j.1471-0528.2010.02774.x","volume":"118","author":"W Kondo","year":"2011","unstructured":"Kondo W, Bourdel N, Tamburro S et al (2011) Complications after surgery for deeply infiltrating pelvic endometriosis. BJOG 118:292\u2013298. https:\/\/doi.org\/10.1111\/j.1471-0528.2010.02774.x","journal-title":"BJOG"},{"key":"3162_CR19","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1016\/j.fertnstert.2005.03.083","volume":"84","author":"P Vercellini","year":"2005","unstructured":"Vercellini P, Pietropaolo G, De Giorgi O, Pasin R, Chiodini A, Crosignani PG (2005) Treatment of symptomatic rectovaginal endometriosis with an estrogen-progestogen combination versus low-dose norethindrone acetate. Fertil Steril 84:1375\u20131387. https:\/\/doi.org\/10.1016\/j.fertnstert.2005.03.083","journal-title":"Fertil Steril"},{"key":"3162_CR20","doi-asserted-by":"publisher","first-page":"3450","DOI":"10.1093\/humrep\/des313","volume":"27","author":"P Vercellini","year":"2012","unstructured":"Vercellini P, Somigliana E, Consonni D, Frattaruolo MP, De Giorgi O, Fedele L (2012) Surgical versus medical treatment for endometriosis-associated severe deep dyspareunia: I. effect on pain during intercourse and patient satisfaction. Hum Reprod 27:3450\u20133459. https:\/\/doi.org\/10.1093\/humrep\/des313","journal-title":"Hum Reprod"},{"key":"3162_CR21","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1016\/j.fertnstert.2017.08.038","volume":"108","author":"P Vercellini","year":"2017","unstructured":"Vercellini P, Buggio L, Somigliana E (2017) Role of medical therapy in the management of deep rectovaginal endometriosis. Fertil Steril 108:913\u2013930. https:\/\/doi.org\/10.1016\/j.fertnstert.2017.08.038","journal-title":"Fertil Steril"},{"key":"3162_CR22","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1097\/LGT.0000000000000326","volume":"21","author":"F Sopracordevole","year":"2017","unstructured":"Sopracordevole F, Moriconi L, Di Giuseppe J et al (2017) Laser excisional treatment for vaginal intraepithelial neoplasia to exclude invasion: what is the risk of complications? J Low Genit Tract Dis 21:311\u2013314. https:\/\/doi.org\/10.1097\/LGT.0000000000000326","journal-title":"J Low Genit Tract Dis"},{"key":"3162_CR23","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1002\/lsm.22941","volume":"50","author":"G Bogani","year":"2018","unstructured":"Bogani G, Ditto A, Martinelli F et al (2018) LASER treatment for women with high-grade vaginal intraepithelial neoplasia: a propensity-matched analysis on the efficacy of ablative versus excisional procedures. Lasers Surg Med 50:933\u2013939. https:\/\/doi.org\/10.1002\/lsm.22941","journal-title":"Lasers Surg Med"},{"key":"3162_CR24","doi-asserted-by":"publisher","first-page":"e9536","DOI":"10.1097\/MD.0000000000009536","volume":"97","author":"S Alborzi","year":"2018","unstructured":"Alborzi S, Rasekhi A, Shomali Z et al (2018) Diagnostic accuracy of magnetic resonance imaging, transvaginal, and transrectal ultrasonography in deep infiltrating endometriosis. Medicine (Baltimore) 97:e9536. https:\/\/doi.org\/10.1097\/MD.0000000000009536","journal-title":"Medicine (Baltimore)"},{"key":"3162_CR25","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1080\/009262300278597","volume":"26","author":"R Rosen","year":"2000","unstructured":"Rosen R, Brown C, Heiman J et al (2000) The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther 26:191\u2013208. https:\/\/doi.org\/10.1080\/009262300278597","journal-title":"J Sex Marital Ther"},{"key":"3162_CR26","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1080\/713847100","volume":"29","author":"CM Meston","year":"2003","unstructured":"Meston CM (2003) Validation of the Female Sexual Function Index (FSFI) in women with female orgasmic disorder and in women with hypoactive sexual desire disorder. J Sex Marital Ther 29:39\u201346. https:\/\/doi.org\/10.1080\/713847100","journal-title":"J Sex Marital Ther"},{"key":"3162_CR27","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","volume":"67","author":"AS Zigmond","year":"1983","unstructured":"Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67:361\u2013370. https:\/\/doi.org\/10.1111\/j.1600-0447.1983.tb09716.x","journal-title":"Acta Psychiatr Scand"},{"key":"3162_CR28","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","volume":"30","author":"JE Ware Jr","year":"1992","unstructured":"Ware JE Jr, Sherbourne CD (1992) The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 30:473\u2013483","journal-title":"Med Care"},{"key":"3162_CR29","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1097\/00005650-199603000-00003","volume":"34","author":"J Ware Jr","year":"1996","unstructured":"Ware J Jr, Kosinski M, Keller SD (1996) A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care 34:220\u2013233. https:\/\/doi.org\/10.1097\/00005650-199603000-00003","journal-title":"Med Care"},{"key":"3162_CR30","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1016\/s0895-4356(98)00109-7","volume":"51","author":"B Gandek","year":"1998","unstructured":"Gandek B, Ware JE, Aaronson NK et al (1998) Cross-validation of item selection and scoring for the SF-12 Health Survey in nine countries: results from the IQOLA Project. Int Qual Life Assess J Clin Epidemiol 51:1171\u20131178. https:\/\/doi.org\/10.1016\/s0895-4356(98)00109-7","journal-title":"Int Qual Life Assess J Clin Epidemiol"},{"key":"3162_CR31","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1007\/s10103-014-1677-2","volume":"30","author":"N Zerbinati","year":"2015","unstructured":"Zerbinati N, Serati M, Origoni M et al (2015) Microscopic and ultrastructural modifications of postmenopausal atrophic vaginal mucosa after fractional carbon dioxide laser treatment. Lasers Med Sci 30:429\u2013436. https:\/\/doi.org\/10.1007\/s10103-014-1677-2","journal-title":"Lasers Med Sci"},{"key":"3162_CR32","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1097\/GME.0000000000000401","volume":"22","author":"S Salvatore","year":"2015","unstructured":"Salvatore S, Leone Roberti Maggiore U, Athanasiou S et al (2015) Histological study on the effects of microablative fractional CO2 laser on atrophic vaginal tissue: an ex vivo study. Menopause 22:845\u2013849. https:\/\/doi.org\/10.1097\/GME.0000000000000401","journal-title":"Menopause"}],"container-title":["Lasers in Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-020-03162-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10103-020-03162-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-020-03162-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,16]],"date-time":"2021-10-16T01:43:12Z","timestamp":1634348592000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10103-020-03162-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,16]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["3162"],"URL":"https:\/\/doi.org\/10.1007\/s10103-020-03162-4","relation":{},"ISSN":["0268-8921","1435-604X"],"issn-type":[{"type":"print","value":"0268-8921"},{"type":"electronic","value":"1435-604X"}],"subject":[],"published":{"date-parts":[[2020,10,16]]},"assertion":[{"value":"6 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 October 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"LB is an unpaid consultant for Merck Sharp & Dome. ES reports grants from Ferring and grants and personal fees from Merck-Serono and Theramex, outside the submitted work. The other authors report no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the local Ethical Committee (determination #28_2016 bis, approval date January 11, 2017). The procedures used in this study adhere to the tenets of the Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}