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The clinical charts of 20 patients of the Dental Clinic of University of Padua (Italy) who underwent a single laser PBM to manage OLP symptomatology were retrospectively analyzed. A 980\u00a0nm diode laser and a flat top handpiece with a 1-cm<jats:sup>2<\/jats:sup> spot area were employed to perform the PBM with a single session protocol. VAS pain scores were assessed before and after the laser PBM, the day after, and on the 7th and 30th days after the treatment. No adverse effects occurred within 30\u00a0days after treatment. The mean VAS-pain score was 3.8 (SD 2.3) before PBM; 2.6 (SD 2.0) after PBM; 1.9 (SD 2.2) on day 1; 2.0 (SD 2.3) on day 7; and 1.5 (SD 2.2) on day 30. VAS pain decreased significantly over time (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). A single session of laser PBM may be safe and effective in reducing pain for symptomatic OLP patients. Further investigations are required to include placebo or topical corticosteroids as comparators.<\/jats:p>","DOI":"10.1007\/s10103-023-03706-4","type":"journal-article","created":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T07:45:02Z","timestamp":1674114302000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Single session of laser photobiomodulation for symptom management of oral lichen planus: a retrospective study"],"prefix":"10.1007","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6302-1090","authenticated-orcid":false,"given":"Andrea","family":"Roccon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0831-3971","authenticated-orcid":false,"given":"Francesco","family":"Cavallin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0110-1017","authenticated-orcid":false,"given":"Gastone","family":"Zanette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6956-6227","authenticated-orcid":false,"given":"Christian","family":"Bacci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,1,19]]},"reference":[{"issue":"6","key":"3706_CR1","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1111\/j.1601-0825.2005.01142.x","volume":"11","author":"D Eisen","year":"2005","unstructured":"Eisen D, Carrozzo M, Sebastian JVB, Thongprasom K, Number V (2005) Oral lichen planus: clinical features and management. 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