{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T07:14:59Z","timestamp":1787987699227,"version":"build-2784847793"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"DOI":"10.1007\/s10103-024-04276-9","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T18:29:09Z","timestamp":1736274549000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Photobiomodulation in carpal tunnel syndrome with pain, strength, and functionality analysis: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"40","author":[{"given":"Ana Cristhini","family":"Lauxen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debora Regina","family":"Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debora Stefhani","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa Beatriz","family":"de Medeiros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dernival","family":"Bertoncello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcia Ros\u00e2ngela","family":"Buzanello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0565-2019","authenticated-orcid":false,"given":"Gladson Ricardo Flor","family":"Bertolini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,8]]},"reference":[{"key":"4276_CR1","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/S1474-4422(22)00432-X","volume":"22","author":"L Padua","year":"2023","unstructured":"Padua L, Cuccagna C, Giovannini S et al (2023) Carpal tunnel syndrome: updated evidence and new questions. Lancet Neurol 22:255\u2013267. https:\/\/doi.org\/10.1016\/S1474-4422(22)00432-X","journal-title":"Lancet Neurol"},{"key":"4276_CR2","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1016\/j.pmr.2018.06.009","volume":"29","author":"L Wang","year":"2018","unstructured":"Wang L (2018) Guiding treatment for carpal tunnel syndrome. Phys Med Rehabil Clin N Am 29:751\u2013760. https:\/\/doi.org\/10.1016\/j.pmr.2018.06.009","journal-title":"Phys Med Rehabil Clin N Am"},{"key":"4276_CR3","first-page":"6","volume":"78","author":"AR Wright","year":"2019","unstructured":"Wright AR, Atkinson RE (2019) Carpal tunnel syndrome: An update for the primary care physician. Hawaii J Health Soc Welf 78:6\u201310","journal-title":"Hawaii J Health Soc Welf"},{"key":"4276_CR4","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1016\/S1474-4422(16)30231-9","volume":"15","author":"L Padua","year":"2016","unstructured":"Padua L, Coraci D, Erra C et al (2016) Carpal tunnel syndrome: clinical features, diagnosis, and management. Lancet Neurol 15:1273\u20131284. https:\/\/doi.org\/10.1016\/S1474-4422(16)30231-9","journal-title":"Lancet Neurol"},{"key":"4276_CR5","doi-asserted-by":"publisher","first-page":"e7333","DOI":"10.7759\/cureus.7333","volume":"12","author":"A Genova","year":"2020","unstructured":"Genova A, Dix O, Saefan A et al (2020) Carpal tunnel syndrome: a review of the literature. Cureus 12:e7333. https:\/\/doi.org\/10.7759\/cureus.7333","journal-title":"Cureus"},{"key":"4276_CR6","doi-asserted-by":"publisher","first-page":"851","DOI":"10.5603\/FM.a2021.0121","volume":"81","author":"K Osiak","year":"2022","unstructured":"Osiak K, Elnazir P, Walocha JA, Pasternak A (2022) Carpal tunnel syndrome: state-of-the-art review. Folia Morphologica (Poland) 81:851\u2013862. https:\/\/doi.org\/10.5603\/FM.a2021.0121","journal-title":"Folia Morphologica (Poland)"},{"key":"4276_CR7","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1002\/lsm.22696","volume":"49","author":"FC Pereira","year":"2017","unstructured":"Pereira FC, Parisi JR, Maglioni CB et al (2017) Antinociceptive effects of low-level laser therapy at 3 and 8 j\/cm2 in a rat model of postoperative pain: possible role of endogenous Opioids. Lasers Surg Med 49:844\u2013851. https:\/\/doi.org\/10.1002\/lsm.22696","journal-title":"Lasers Surg Med"},{"key":"4276_CR8","doi-asserted-by":"publisher","first-page":"3011","DOI":"10.1007\/s10103-022-03590-4","volume":"37","author":"S Kulkarni","year":"2022","unstructured":"Kulkarni S, George R, Love R, Ranjitkar S (2022) Effectiveness of photobiomodulation in reducing pain and producing dental analgesia: a systematic review. Lasers Med Sci 37:3011\u20133019. https:\/\/doi.org\/10.1007\/s10103-022-03590-4","journal-title":"Lasers Med Sci"},{"key":"4276_CR9","doi-asserted-by":"publisher","first-page":"111513","DOI":"10.1016\/j.jphotobiol.2019.111513","volume":"196","author":"GR Pigatto","year":"2019","unstructured":"Pigatto GR, Silva CS, Parizotto NA (2019) Photobiomodulation therapy reduces acute pain and inflammation in mice. J Photochem Photobiol B 196:111513. https:\/\/doi.org\/10.1016\/j.jphotobiol.2019.111513","journal-title":"J Photochem Photobiol B"},{"key":"4276_CR10","doi-asserted-by":"publisher","first-page":"112644","DOI":"10.1016\/j.jphotobiol.2022.112644","volume":"239","author":"CA Coracini","year":"2023","unstructured":"Coracini CA, Zazula MF, Ferreira MO et al (2023) Acute effects of photobiomodulation applied on the dorsal root ganglion in gout model-induced rats. J Photochem Photobiol B 239:112644. https:\/\/doi.org\/10.1016\/j.jphotobiol.2022.112644","journal-title":"J Photochem Photobiol B"},{"key":"4276_CR11","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1007\/s10103-017-2234-6","volume":"32","author":"AH Bekhet","year":"2017","unstructured":"Bekhet AH, Ragab B, Abushouk AI et al (2017) Efficacy of low-level laser therapy in carpal tunnel syndrome management: a systematic review and meta-analysis. Lasers Med Sci 32:1439\u20131448. https:\/\/doi.org\/10.1007\/s10103-017-2234-6","journal-title":"Lasers Med Sci"},{"key":"4276_CR12","doi-asserted-by":"publisher","first-page":"S82","DOI":"10.15171\/jlms.2019.S15","volume":"10","author":"SM Rayegani","year":"2019","unstructured":"Rayegani SM, Moradi-Joo M, Raeissadat SA et al (2019) Effectiveness of low-level laser therapy compared to ultrasound in patients with carpal tunnel syndrome: A systematic review and meta-analysis. J Lasers Med Sci 10:S82\u2013S89. https:\/\/doi.org\/10.15171\/jlms.2019.S15","journal-title":"J Lasers Med Sci"},{"key":"4276_CR13","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1016\/j.apmr.2017.06.002","volume":"99","author":"TP Franke","year":"2018","unstructured":"Franke TP, Koes BW, Geelen SJ, Huisstede BM (2018) Do patients with carpal tunnel syndrome benefit from low-level laser therapy? A systematic review of randomized controlled trials. Arch Phys Med Rehabil 99:1650-1659.e15. https:\/\/doi.org\/10.1016\/j.apmr.2017.06.002","journal-title":"Arch Phys Med Rehabil"},{"key":"4276_CR14","doi-asserted-by":"publisher","first-page":"4922","DOI":"10.1111\/jcmm.13757","volume":"22","author":"NHC Souza","year":"2018","unstructured":"Souza NHC, Mesquita-Ferrari RA, Rodrigues MFSD et al (2018) Photobiomodulation and different macrophages phenotypes during muscle tissue repair. J Cell Mol Med 22:4922\u20134934. https:\/\/doi.org\/10.1111\/jcmm.13757","journal-title":"J Cell Mol Med"},{"key":"4276_CR15","doi-asserted-by":"publisher","first-page":"8843179","DOI":"10.1155\/2021\/8843179","volume":"2021","author":"D da Silva","year":"2021","unstructured":"da Silva D, Crous A, Abrahamse H (2021) Photobiomodulation: An effective approach to enhance proliferation and differentiation of adipose-derived stem cells into osteoblasts. Stem Cells Int 2021:8843179. https:\/\/doi.org\/10.1155\/2021\/8843179","journal-title":"Stem Cells Int"},{"key":"4276_CR16","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1007\/s10103-019-02779-4","volume":"35","author":"FC Jana Neto","year":"2020","unstructured":"Jana Neto FC, Martimbianco ALC, de Andrade RP et al (2020) Effects of photobiomodulation in the treatment of fractures: a systematic review and meta-analysis of randomized clinical trials. Lasers Med Sci 35:513\u2013522. https:\/\/doi.org\/10.1007\/s10103-019-02779-4","journal-title":"Lasers Med Sci"},{"key":"4276_CR17","doi-asserted-by":"publisher","first-page":"e202100271","DOI":"10.1002\/jbio.202100271","volume":"15","author":"TCC Lopez","year":"2022","unstructured":"Lopez TCC, dos S Malavazzi TC, Rodrigues MFSD et al (2022) Histological and biochemical effects of preventive and therapeutic vascular photobiomodulation on rat muscle injury. J Biophotonics 15:e202100271. https:\/\/doi.org\/10.1002\/jbio.202100271","journal-title":"J Biophotonics"},{"key":"4276_CR18","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1007\/s10103-020-03168-y\/Published","volume":"36","author":"WR Beasi","year":"2021","unstructured":"Beasi WR, Toffoli LV, Pelosi GG et al (2021) Effects of photobiomodulation and swimming on gene expression in rats with the tibialis anterior muscle injury. Lasers Med Sci 36:1379\u20131387. https:\/\/doi.org\/10.1007\/s10103-020-03168-y\/Published","journal-title":"Lasers Med Sci"},{"key":"4276_CR19","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1007\/s10103-018-2510-0","volume":"33","author":"LA da Silva NetoTrajano","year":"2018","unstructured":"da Silva NetoTrajano LA, Trajano ETL, da Silva Sergio LP et al (2018) Photobiomodulation effects on mRNA levels from genomic and chromosome stabilization genes in injured muscle. Lasers Med Sci 33:1513\u20131519. https:\/\/doi.org\/10.1007\/s10103-018-2510-0","journal-title":"Lasers Med Sci"},{"key":"4276_CR20","doi-asserted-by":"publisher","first-page":"14293","DOI":"10.3390\/ijms241814293","volume":"24","author":"R Zhang","year":"2023","unstructured":"Zhang R, Qu J (2023) The mechanisms and efficacy of photobiomodulation therapy for arthritis: A comprehensive review. Int J Mol Sci 24:14293. https:\/\/doi.org\/10.3390\/ijms241814293","journal-title":"Int J Mol Sci"},{"key":"4276_CR21","doi-asserted-by":"publisher","first-page":"6565","DOI":"10.3390\/ijms21186565","volume":"21","author":"LM Ailioaie","year":"2020","unstructured":"Ailioaie LM, Litscher G (2020) Molecular and cellular mechanisms of arthritis in children and adults: New perspectives on applied photobiomodulation. Int J Mol Sci 21:6565. https:\/\/doi.org\/10.3390\/ijms21186565","journal-title":"Int J Mol Sci"},{"key":"4276_CR22","doi-asserted-by":"publisher","first-page":"1122581","DOI":"10.3389\/fimmu.2023.1122581","volume":"14","author":"JH Ryu","year":"2023","unstructured":"Ryu JH, Park J, Kim BY et al (2023) Photobiomodulation ameliorates inflammatory parameters in fibroblast-like synoviocytes and experimental animal models of rheumatoid arthritis. Front Immunol 14:1122581. https:\/\/doi.org\/10.3389\/fimmu.2023.1122581","journal-title":"Front Immunol"},{"key":"4276_CR23","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1007\/s10103-021-03372-4","volume":"37","author":"CA Coracini","year":"2022","unstructured":"Coracini CA, dos Santos SF, Bertolini GRF (2022) The use of LED therapy to treat synovial joints disorders: scoping review. Lasers Med Sci 37:701\u2013721. https:\/\/doi.org\/10.1007\/s10103-021-03372-4","journal-title":"Lasers Med Sci"},{"key":"4276_CR24","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1111\/php.13415","volume":"97","author":"GML Della Santa","year":"2021","unstructured":"Della Santa GML, Ferreira MC, Machado TPG et al (2021) Effects of photobiomodulation therapy (LED 630 nm) on muscle and nerve histomorphometry after axonotmesis. Photochem Photobiol 97:1116\u20131122. https:\/\/doi.org\/10.1111\/php.13415","journal-title":"Photochem Photobiol"},{"key":"4276_CR25","doi-asserted-by":"publisher","first-page":"2155","DOI":"10.1007\/s10103-017-2359-7","volume":"32","author":"L Andreo","year":"2017","unstructured":"Andreo L, Soldera CB, Ribeiro BG et al (2017) Effects of photobiomodulation on experimental models of peripheral nerve injury. Lasers Med Sci 32:2155\u20132165","journal-title":"Lasers Med Sci"},{"key":"4276_CR26","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1111\/php.13255","volume":"96","author":"L Andreo","year":"2020","unstructured":"Andreo L, Ribeiro BG, Alves AN et al (2020) Effects of photobiomodulation with low-level laser therapy on muscle repair following a peripheral nerve injury in wistar rats. Photochem Photobiol 96:1124\u20131132. https:\/\/doi.org\/10.1111\/php.13255","journal-title":"Photochem Photobiol"},{"key":"4276_CR27","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1007\/s10103-020","volume":"36","author":"AMC Ibarra","year":"2021","unstructured":"Ibarra AMC, Biasotto-Gonzalez DA, Kohatsu EYI et al (2021) Photobiomodulation on trigeminal neuralgia: systematic review. Lasers Med Sci 36:715\u2013722. https:\/\/doi.org\/10.1007\/s10103-020","journal-title":"Lasers Med Sci"},{"key":"4276_CR28","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/j.jaad.2016.03.050","volume":"75","author":"YT Chen","year":"2016","unstructured":"Chen YT, Wang HH, Wang TJ et al (2016) Early application of low-level laser may reduce the incidence of postherpetic neuralgia (PHN). J Am Acad Dermatol 75:572\u2013577. https:\/\/doi.org\/10.1016\/j.jaad.2016.03.050","journal-title":"J Am Acad Dermatol"},{"key":"4276_CR29","doi-asserted-by":"publisher","first-page":"d5928","DOI":"10.1136\/bmj.d5928","volume":"343","author":"JPT Higgins","year":"2011","unstructured":"Higgins JPT, Altman DG, Gotzsche PC et al (2011) The Cochrane Collaboration\u2019s tool for assessing risk of bias in randomised trials. BMJ 343:d5928\u2013d5928. https:\/\/doi.org\/10.1136\/bmj.d5928","journal-title":"BMJ"},{"key":"4276_CR30","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1258\/1355819021927674","volume":"7","author":"J Higgins","year":"2002","unstructured":"Higgins J, Thompson S, Deeks J, Altman D (2002) Statistical heterogeneity in systematic reviews of clinical trials: A critical appraisal of guidelines and practice. J Health Serv Res Policy 7:51\u201361. https:\/\/doi.org\/10.1258\/1355819021927674","journal-title":"J Health Serv Res Policy"},{"key":"4276_CR31","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","volume":"327","author":"J Higgins","year":"2003","unstructured":"Higgins J, Thompson S, Deeks J, Altman D (2003) Measuring inconsistency in meta-analyses Testing for heterogeneity. BMJ 327:557\u2013560","journal-title":"BMJ"},{"key":"4276_CR32","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1589\/jpts.23.661","volume":"23","author":"J-A Jiang","year":"2011","unstructured":"Jiang J-A, Chang W-D, Tung Lai P, Lin H-Y (2011) Low-level laser treatment relieves pain and neurological symptoms in patients with carpal tunnel syndrome. J Phys Ther Sci 23:661\u2013665","journal-title":"J Phys Ther Sci"},{"key":"4276_CR33","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1007\/s10103-014-1527-2","volume":"29","author":"Y Fusakul","year":"2014","unstructured":"Fusakul Y, Aranyavalai T, Saensri P, Thiengwittayaporn S (2014) Low-level laser therapy with a wrist splint to treat carpal tunnel syndrome: A double-blinded randomized controlled trial. Lasers Med Sci 29:1279\u20131287. https:\/\/doi.org\/10.1007\/s10103-014-1527-2","journal-title":"Lasers Med Sci"},{"key":"4276_CR34","doi-asserted-by":"publisher","first-page":"733","DOI":"10.23736\/S1973-9087.19.05835-0","volume":"56","author":"K Ezzati","year":"2020","unstructured":"Ezzati K, Laakso EL, Saberi A et al (2020) A comparative study of the dose-dependent effects of low level and high intensity photobiomodulation (laser) therapy on pain and electrophysiological parameters in patients with carpal tunnel syndrome. Eur J Phys Rehabil Med 56:733\u2013740. https:\/\/doi.org\/10.23736\/S1973-9087.19.05835-0","journal-title":"Eur J Phys Rehabil Med"},{"key":"4276_CR35","doi-asserted-by":"publisher","first-page":"459","DOI":"10.3233\/BMR-150640","volume":"29","author":"RI Barbosa","year":"2016","unstructured":"Barbosa RI, de Fonseca M, CR, Rodrigues EK da S, et al (2016) Efficacy of low-level laser therapy associated to orthoses for patients with carpal tunnel syndrome: A randomized single-blinded controlled trial. J Back Musculoskelet Rehabil 29:459\u2013466. https:\/\/doi.org\/10.3233\/BMR-150640","journal-title":"J Back Musculoskelet Rehabil"},{"key":"4276_CR36","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1002\/mus.20095","volume":"30","author":"J Irvine","year":"2004","unstructured":"Irvine J, Chong SL, Amirjani N, Chan KM (2004) Double-blind randomized controlled trial of low-level laser therapy in Carpal Tunnel Syndrome. Muscle Nerve 30:182\u2013187. https:\/\/doi.org\/10.1002\/mus.20095","journal-title":"Muscle Nerve"},{"key":"4276_CR37","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1089\/pho.2006.2032","volume":"25","author":"D Evcik","year":"2007","unstructured":"Evcik D, Kavuncu V, Cakir T et al (2007) Laser therapy in the treatment of carpal tunnel syndrome: A randomized controlled trial. Photomed Laser Surg 25:34\u201339. https:\/\/doi.org\/10.1089\/pho.2006.2032","journal-title":"Photomed Laser Surg"},{"key":"4276_CR38","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1089\/pho.2007.2234","volume":"26","author":"WD Chang","year":"2008","unstructured":"Chang WD, Wu JH, Jiang JA et al (2008) Carpal tunnel syndrome treated with a diode laser: A controlled treatment of the transverse carpal ligament. Photomed Laser Surg 26:551\u2013557. https:\/\/doi.org\/10.1089\/pho.2007.2234","journal-title":"Photomed Laser Surg"},{"key":"4276_CR39","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1007\/s10067-009-1213-0","volume":"28","author":"I Yagci","year":"2009","unstructured":"Yagci I, Elmas O, Akcan E et al (2009) Comparison of splinting and splinting plus low-level laser therapy in idiopathic carpal tunnel syndrome. Clin Rheumatol 28:1059\u20131065. https:\/\/doi.org\/10.1007\/s10067-009-1213-0","journal-title":"Clin Rheumatol"},{"key":"4276_CR40","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1007\/s00296-010-1652-6","volume":"32","author":"F Tascioglu","year":"2012","unstructured":"Tascioglu F, Degirmenci NA, Ozkan S, Mehmetoglu O (2012) Low-level laser in the treatment of carpal tunnel syndrome: Clinical, electrophysiological, and ultrasonographical evaluation. Rheumatol Int 32:409\u2013415. https:\/\/doi.org\/10.1007\/s00296-010-1652-6","journal-title":"Rheumatol Int"},{"key":"4276_CR41","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1089\/pho.2013.3563","volume":"32","author":"M Lazovic","year":"2014","unstructured":"Lazovic M, Ilic-Stojanovic O, Kocic M et al (2014) Placebo-controlled investigation of low-level laser therapy to treat carpal tunnel syndrome. Photomed Laser Surg 32:336\u2013344. https:\/\/doi.org\/10.1089\/pho.2013.3563","journal-title":"Photomed Laser Surg"},{"key":"4276_CR42","doi-asserted-by":"publisher","first-page":"73","DOI":"10.34172\/JLMS.2020.S12","volume":"11","author":"F Hojjati","year":"2020","unstructured":"Hojjati F, Mohammad Hosein A, Ismail Ebrahimi T et al (2020) The effect of high-power and low-power lasers on symptoms and the nerve conduction study in patients with carpal tunnel syndrome. A prospective randomized single-blind clinical trial. J Lasers Med Sci 11:73\u201379. https:\/\/doi.org\/10.34172\/JLMS.2020.S12","journal-title":"J Lasers Med Sci"},{"key":"4276_CR43","doi-asserted-by":"publisher","first-page":"18","DOI":"10.4103\/jasmr.jasmr_7_20","volume":"15","author":"A Elgendy","year":"2020","unstructured":"Elgendy A, Ali M, Medhat A et al (2020) Therapeutic and photobiomodulation effects of low-level laser irradiation on Egyptian patients with carpal tunnel syndrome: a placebo-controlled study. J Arab Soc Med Res 15:18\u201324. https:\/\/doi.org\/10.4103\/jasmr.jasmr_7_20","journal-title":"J Arab Soc Med Res"},{"key":"4276_CR44","doi-asserted-by":"publisher","first-page":"19","DOI":"10.46497\/ArchRheumatol.2022.8605","volume":"37","author":"M Nalbant","year":"2022","unstructured":"Nalbant M, Yemi\u015fci O\u00dc, \u00d6zen S, Tezcan \u015e (2022) Ultrasonographic and electrophysiological outcomes of carpal tunnel syndrome treated with low-level laser therapy: A double-blind, prospective, randomized, sham-controlled study. Arch Rheumatol 37:19\u201330. https:\/\/doi.org\/10.46497\/ArchRheumatol.2022.8605","journal-title":"Arch Rheumatol"},{"key":"4276_CR45","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1002\/jum.14669","volume":"38","author":"S Tezcan","year":"2019","unstructured":"Tezcan S, Ozturk FU, Uslu N et al (2019) Carpal tunnel syndrome: Evaluation of the effects of low-level laser therapy with ultrasound strain imaging. J Ultrasound Med 38:113\u2013122. https:\/\/doi.org\/10.1002\/jum.14669","journal-title":"J Ultrasound Med"},{"key":"4276_CR46","doi-asserted-by":"publisher","first-page":"e4424","DOI":"10.1097\/MD.0000000000004424","volume":"95","author":"ZJ Li","year":"2016","unstructured":"Li ZJ, Wang Y, Zhang HF et al (2016) Effectiveness of low-level laser on carpal tunnel syndrome: A meta-analysis of previously reported randomized trials. Medicine (United States) 95:e4424. https:\/\/doi.org\/10.1097\/MD.0000000000004424","journal-title":"Medicine (United States)"},{"key":"4276_CR47","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.jpain.2021.02.005","volume":"22","author":"K Cheng","year":"2021","unstructured":"Cheng K, Martin LF, Slepian MJ et al (2021) Mechanisms and pathways of pain photobiomodulation: A narrative review. Journal of Pain 22:763\u2013777. https:\/\/doi.org\/10.1016\/j.jpain.2021.02.005","journal-title":"Journal of Pain"},{"key":"4276_CR48","doi-asserted-by":"publisher","first-page":"282","DOI":"10.23736\/s1973","volume":"58","author":"MF De Oliveira","year":"2021","unstructured":"De Oliveira MF, Johnson DS, Demchak T et al (2021) Low-intensity laser and led (photobiomodulation therapy) for pain control of the most common musculoskeletal conditions. Eur J Phys Rehabil Med 58:282\u2013289. https:\/\/doi.org\/10.23736\/s1973","journal-title":"Eur J Phys Rehabil Med"},{"key":"4276_CR49","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1590\/S0004-282X2011000300017","volume":"69","author":"GRF Bertolini","year":"2011","unstructured":"Bertolini GRF, Artifon EL, da Silva TS et al (2011) Low-level laser therapy, at 830 nm, for pain reduction in experimental model of rats with sciatica | Laser de baixa pot\u00eancia, 830 nm, na redu\u00e7\u00e3o da dor em ratos submetidos \u00e0 modelo experimental de ciatalgia. Arq Neuropsiquiatr 69:356\u2013359","journal-title":"Arq Neuropsiquiatr"},{"key":"4276_CR50","doi-asserted-by":"publisher","first-page":"332","DOI":"10.34172\/jlms.2020.54","volume":"11","author":"LL Sasso","year":"2020","unstructured":"Sasso LL, de Souza LG, Girasol CE et al (2020) Photobiomodulation in sciatic nerve crush injuries in rodents: A systematic review of the literature and perspectives for clinical treatment. J Lasers Med Sci 11:332\u2013344. https:\/\/doi.org\/10.34172\/jlms.2020.54","journal-title":"J Lasers Med Sci"},{"key":"4276_CR51","doi-asserted-by":"publisher","first-page":"4347","DOI":"10.3390\/ijms22094347","volume":"22","author":"S Ravera","year":"2021","unstructured":"Ravera S, Colombo E, Pasquale C et al (2021) Mitochondrial bioenergetic, photobiomodulation and trigeminal branches nerve damage, what\u2019s the connection? A review. Int J Mol Sci 22:4347","journal-title":"Int J Mol Sci"},{"key":"4276_CR52","doi-asserted-by":"publisher","first-page":"e0287833","DOI":"10.1371\/journal.pone.0287833","volume":"18","author":"Y Ma","year":"2023","unstructured":"Ma Y, Yang M, Chen X et al (2023) The effectiveness of photobiomodulation therapy on inferior alveolar nerve injury: A systematic review and META-analysis. PLoS ONE 18:e0287833. https:\/\/doi.org\/10.1371\/journal.pone.0287833","journal-title":"PLoS ONE"},{"key":"4276_CR53","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1515\/revneuro-2019-0063","volume":"31","author":"F Salehpour","year":"2020","unstructured":"Salehpour F, Gholipour-Khalili S, Farajdokht F et al (2020) Therapeutic potential of intranasal photobiomodulation therapy for neurological and neuropsychiatric disorders: A narrative review. Rev Neurosci 31:269\u2013286. https:\/\/doi.org\/10.1515\/revneuro-2019-0063","journal-title":"Rev Neurosci"},{"key":"4276_CR54","doi-asserted-by":"publisher","first-page":"1719","DOI":"10.1007\/s10103-017-2237-3","volume":"32","author":"BM \u00d6kmen","year":"2017","unstructured":"\u00d6kmen BM, \u00d6kmen K (2017) Comparison of photobiomodulation therapy and suprascapular nerve-pulsed radiofrequency in chronic shoulder pain: a randomized controlled, single-blind, clinical trial. Lasers Med Sci 32:1719\u20131726. https:\/\/doi.org\/10.1007\/s10103-017-2237-3","journal-title":"Lasers Med Sci"},{"key":"4276_CR55","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.jphotobiol.2016.08.025","volume":"164","author":"ALM de Andrade","year":"2016","unstructured":"de Andrade ALM, Bossini PS, Parizotto NA (2016) Use of low level laser therapy to control neuropathic pain: A systematic review. J Photochem Photobiol B 164:36\u201342. https:\/\/doi.org\/10.1016\/j.jphotobiol.2016.08.025","journal-title":"J Photochem Photobiol B"},{"key":"4276_CR56","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1590\/S0004-282X2011000300017","volume":"69","author":"G Ricardo","year":"2011","unstructured":"Ricardo G, Bertolini F, Artifon L et al (2011) Low-level laser therapy, at 830 nm, for pain reduction in experimental model of rats with sciatica. Arq Neuropsiquiatr 69:356\u2013359","journal-title":"Arq Neuropsiquiatr"},{"key":"4276_CR57","doi-asserted-by":"publisher","first-page":"29","DOI":"10.5152\/imj.2018.60863","volume":"19","author":"A Akar","year":"2018","unstructured":"Akar A, SayinerCaglar N, Aytekin E et al (2018) Efficacy of low level laser therapy in the conservative treatment of carpal tunnel syndrome. Istanbul Med J 19:29\u201334. https:\/\/doi.org\/10.5152\/imj.2018.60863","journal-title":"Istanbul Med J"},{"key":"4276_CR58","first-page":"4","volume":"20","author":"MS Aboonq","year":"2015","unstructured":"Aboonq MS (2015) Pathophysiology of carpal tunnel syndrome. Neurosci J 20:4\u20139","journal-title":"Neurosci J"},{"key":"4276_CR59","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.artd.2022.10.016","volume":"19","author":"H Bahrami","year":"2023","unstructured":"Bahrami H, Moharrami A, Mirghaderi P, Mortazavi SMJ (2023) Low-level laser and light therapy after total knee arthroplasty improves postoperative pain and functional outcomes: A three-arm randomized clinical trial. Arthroplast Today 19:1\u20139. https:\/\/doi.org\/10.1016\/j.artd.2022.10.016","journal-title":"Arthroplast Today"},{"key":"4276_CR60","unstructured":"WALT Recommended treatment doses for Low Level Laser Therapy. https:\/\/waltpbm.org\/wp-content\/uploads\/2021\/08\/Dose_table_780-860nm_for_Low_Level_Laser_Therapy_WALT-2010.pdf. Accessed 7 Jan 2024"}],"container-title":["Lasers in Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-024-04276-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10103-024-04276-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-024-04276-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T07:21:33Z","timestamp":1771399293000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10103-024-04276-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,8]]},"references-count":60,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4276"],"URL":"https:\/\/doi.org\/10.1007\/s10103-024-04276-9","relation":{},"ISSN":["1435-604X"],"issn-type":[{"value":"1435-604X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,8]]},"assertion":[{"value":"27 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Since this is a secondary study (systematic review with meta-analysis), the Research Ethics Committee of the State University of Western Paran\u00e1 has waived submission of the research project for possible approval.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical statement"}},{"value":"The authors declare that they have no potential conflict of interest regarding the research, authorship and\/or publication of this article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}}],"article-number":"12"}}