{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T20:27:31Z","timestamp":1780345651698,"version":"3.54.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T00:00:00Z","timestamp":1736812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T00:00:00Z","timestamp":1736812800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Hangzhou Medical Key Discipline Construction Project","award":["Grant No. [37]21-3"],"award-info":[{"award-number":["Grant No. [37]21-3"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"DOI":"10.1007\/s10103-025-04282-5","type":"journal-article","created":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T23:48:34Z","timestamp":1736812114000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Establishing an animal model for post-inflammatory hyperpigmentation following fractional CO2 laser application"],"prefix":"10.1007","volume":"40","author":[{"given":"Jiangfeng","family":"Feng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuzu","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beilei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenzhong","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,14]]},"reference":[{"issue":"4","key":"4282_CR1","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1016\/j.jaad.2017.01.035","volume":"77","author":"N Silpa-Archa","year":"2017","unstructured":"Silpa-Archa N, Kohli I, Chaowattanapanit S et al (2017) Postinflammatory hyperpigmentation: a comprehensive overview: epidemiology, pathogenesis, clinical presentation, and noninvasive assessment technique. J Am Acad Dermatol 77(4):591\u2013605","journal-title":"J Am Acad Dermatol"},{"issue":"3","key":"4282_CR2","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1111\/j.1524-4725.2009.01434.x","volume":"36","author":"AI Metelitsa","year":"2010","unstructured":"Metelitsa AI, Alster TS (2010) Fractionated laser skin resurfacing treatment complications: a review. Dermatol Surg 36(3):299\u2013306","journal-title":"Dermatol Surg"},{"issue":"6","key":"4282_CR3","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1111\/pcmr.12986","volume":"34","author":"A Nautiyal","year":"2021","unstructured":"Nautiyal A, Wairkar S (2021) Management of hyperpigmentation: current treatments and emerging therapies. Pigment cell Melanoma Res 34(6):1000\u20131014","journal-title":"Pigment cell Melanoma Res"},{"issue":"6","key":"4282_CR4","doi-asserted-by":"publisher","first-page":"1692","DOI":"10.1111\/jocd.13735","volume":"20","author":"M Wei","year":"2021","unstructured":"Wei M, Li L, Zhang XF et al (2021) Fusidic acid cream comparatively minimizes signs of inflammation and postinflammatory hyperpigmentation after ablative fractional CO2 laser resurfacing in Chinese patients: a randomized controlled trial. J Cosmet Dermatol 20(6):1692\u20131699","journal-title":"J Cosmet Dermatol"},{"issue":"3","key":"4282_CR5","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1111\/pcmr.13038","volume":"35","author":"J Maghfour","year":"2022","unstructured":"Maghfour J, Olayinka J, Hamzavi IH et al (2022) A focused review on the pathophysiology of post-inflammatory hyperpigmentation. Pigment Cell Melanoma Res 35(3):320\u2013327","journal-title":"Pigment Cell Melanoma Res"},{"issue":"8","key":"4282_CR6","doi-asserted-by":"publisher","first-page":"763","DOI":"10.36849\/JDD.2020.4887","volume":"19","author":"A Shenoy","year":"2020","unstructured":"Shenoy A, Madan R, Post-Inflammatory Hyperpigmentation (2020) A review of treatment strategies. J Drugs Dermatol 19(8):763\u2013768","journal-title":"J Drugs Dermatol"},{"issue":"5","key":"4282_CR7","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1002\/lsm.20512","volume":"39","author":"HH Chan","year":"2007","unstructured":"Chan HH, Manstein D, Yu C et al (2007) The prevalence and risk factors of post-inflammatory hyperpigmentation after fractional resurfacing in asians. Lasers Surg Medicine: Official J Am Soc Laser Med Surg 39(5):381\u2013385","journal-title":"Lasers Surg Medicine: Official J Am Soc Laser Med Surg"},{"issue":"4","key":"4282_CR8","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1177\/1090820X10380547","volume":"30","author":"JP Farkas","year":"2010","unstructured":"Farkas JP, Richardson JA, Brown SA et al (2010) TUNEL assay to characterize acute histopathological injury following treatment with the active and deep Mode fractional short-pulse CO2 devices. Aesthetic Surg J 30(4):603\u2013613","journal-title":"Aesthetic Surg J"},{"issue":"4","key":"4282_CR9","doi-asserted-by":"publisher","first-page":"190","DOI":"10.3109\/14764170903356465","volume":"11","author":"GH Sasaki","year":"2009","unstructured":"Sasaki GH, Travis HM, Tucker B (2009) Fractional CO2 laser resurfacing of photoaged facial and non-facial skin: histologic and clinical results and side effects. J Cosmet Laser Therapy 11(4):190\u2013201","journal-title":"J Cosmet Laser Therapy"},{"issue":"2","key":"4282_CR10","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1111\/cup.12849","volume":"44","author":"JY Park","year":"2017","unstructured":"Park JY, Park JH, Kim SJ et al (2017) Two histopathological patterns of postinflammatory hyperpigmentation: epidermal and dermal. J Cutan Pathol 44(2):118\u2013124","journal-title":"J Cutan Pathol"},{"issue":"1","key":"4282_CR11","doi-asserted-by":"publisher","first-page":"85","DOI":"10.4062\/biomolther.2015.165","volume":"24","author":"TH Lee","year":"2016","unstructured":"Lee TH, Kang JH, Seo JO et al (2016) Anti-melanogenic potentials of nanoparticles from calli of resveratrol-enriched rice against UVB-induced hyperpigmentation in guinea pig skin. Biomolecules Ther 24(1):85","journal-title":"Biomolecules Ther"},{"issue":"1","key":"4282_CR12","doi-asserted-by":"publisher","first-page":"19216","DOI":"10.1038\/srep19216","volume":"6","author":"WH Jang","year":"2016","unstructured":"Jang WH, Shim S, Wang T et al (2016) In vivo characterization of early-stage radiation skin injury in a mouse model by two-photon microscopy. Sci Rep 6(1):19216","journal-title":"Sci Rep"},{"issue":"9","key":"4282_CR13","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1002\/lsm.20974","volume":"42","author":"NP Chan","year":"2010","unstructured":"Chan NP, Ho SG, Yeung CK et al (2010) Fractional ablative carbon dioxide laser resurfacing for skin rejuvenation and acne scars in asians. Lasers Surg Med 42(9):775\u2013783","journal-title":"Lasers Surg Med"},{"issue":"1","key":"4282_CR14","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1111\/pcmr.12911","volume":"34","author":"S Nakano","year":"2021","unstructured":"Nakano S, Abe Y, Nakajima K et al (2021) Establishment of a mouse model for post-inflammatory hyperpigmentation. Pigment Cell Melanoma Res 34(1):101\u2013110","journal-title":"Pigment Cell Melanoma Res"},{"key":"4282_CR15","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1134\/S0026893319050121","volume":"53","author":"M Nosenko","year":"2019","unstructured":"Nosenko M, Ambaryan S, Drutskaya M (2019) Proinflammatory cytokines and skin wound healing in mice. Mol Biol 53:653\u2013664","journal-title":"Mol Biol"},{"issue":"12","key":"4282_CR16","doi-asserted-by":"publisher","first-page":"2757","DOI":"10.1111\/jdv.16404","volume":"34","author":"R Kapoor","year":"2020","unstructured":"Kapoor R, Dhatwalia S, Kumar R et al (2020) Emerging role of dermal compartment in skin pigmentation: comprehensive review. J Eur Acad Dermatol Venereol 34(12):2757\u20132765","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"8","key":"4282_CR17","doi-asserted-by":"publisher","first-page":"3970","DOI":"10.3390\/ijms22083970","volume":"22","author":"MR Hossain","year":"2021","unstructured":"Hossain MR, Ansary TM, Komine M et al (2021) Diversified stimuli-induced inflammatory pathways cause skin pigmentation. Int J Mol Sci 22(8):3970","journal-title":"Int J Mol Sci"},{"issue":"1","key":"4282_CR18","doi-asserted-by":"publisher","first-page":"30","DOI":"10.5114\/pdia.2013.33376","volume":"30","author":"M Cichorek","year":"2013","unstructured":"Cichorek M, Wachulska M, Stasiewicz A et al (2013) Skin melanocytes: biology and development. Adv Dermatology Allergology\/Post\u0119py Dermatologii i Alergologii 30(1):30\u201341","journal-title":"Adv Dermatology Allergology\/Post\u0119py Dermatologii i Alergologii"},{"issue":"2","key":"4282_CR19","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.jdermsci.2017.06.018","volume":"88","author":"Y Wang","year":"2017","unstructured":"Wang Y, Viennet C, Robin S et al (2017) Precise role of dermal fibroblasts on melanocyte pigmentation. J Dermatol Sci 88(2):159\u2013166","journal-title":"J Dermatol Sci"},{"issue":"1","key":"4282_CR20","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1034\/j.1600-0749.2000.130103.x","volume":"13","author":"R Halaban","year":"2000","unstructured":"Halaban R (2000) The regulation of normal melanocyte proliferation. Pigment Cell Res 13(1):4\u201314","journal-title":"Pigment Cell Res"},{"issue":"3","key":"4282_CR21","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1042\/bj3301235","volume":"330","author":"G IMOKAWA","year":"1998","unstructured":"IMOKAWA G, YADA Y, MORISAKI N et al (1998) Biological characterization of human fibroblast-derived mitogenic factors for human melanocytes. Biochem J 330(3):1235\u20131239","journal-title":"Biochem J"},{"issue":"1","key":"4282_CR22","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.jdermsci.2013.03.012","volume":"71","author":"T Hirobe","year":"2013","unstructured":"Hirobe T, Hasegawa K, Furuya R et al (2013) Effects of fibroblast-derived factors on the proliferation and differentiation of human melanocytes in culture. J Dermatol Sci 71(1):45\u201357","journal-title":"J Dermatol Sci"},{"issue":"3","key":"4282_CR23","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1055\/s-0032-1329414","volume":"26","author":"WM Ramsdell","year":"2012","unstructured":"Ramsdell WM (2012) Fractional carbon dioxide laser resurfacing. Semin Plast Surg 26(3):125\u2013130","journal-title":"Semin Plast Surg"},{"issue":"2","key":"4282_CR24","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1055\/s-0037-1606096","volume":"34","author":"Y Xu","year":"2018","unstructured":"Xu Y, Deng Y (2018) Ablative fractional CO2 laser for facial atrophic acne scars. Facial Plast Surg 34(2):205\u2013219","journal-title":"Facial Plast Surg"},{"issue":"5","key":"4282_CR25","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1002\/lsm.20512","volume":"39","author":"HH Chan","year":"2007","unstructured":"Chan HH, Manstein D, Yu C et al (2007) The prevalence and risk factors of post-inflammatory hyperpigmentation after fractional resurfacing in asians. Lasers Surg Med 39(5):381\u2013385","journal-title":"Lasers Surg Med"},{"issue":"2","key":"4282_CR26","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.dsi.2012.09.009","volume":"31","author":"PF Hsiao","year":"2013","unstructured":"Hsiao PF, Lin YC, Huang CC et al (2013) Efficacy and safety of a single treatment using a 10,600-nm carbon dioxide fractional laser for mild-to-moderate atrophic acne scars in Asian skin. Dermatologica Sinica 31(2):59\u201363","journal-title":"Dermatologica Sinica"}],"container-title":["Lasers in Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-025-04282-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10103-025-04282-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-025-04282-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T07:23:27Z","timestamp":1771399407000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10103-025-04282-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,14]]},"references-count":26,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4282"],"URL":"https:\/\/doi.org\/10.1007\/s10103-025-04282-5","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-4815813\/v1","asserted-by":"object"}]},"ISSN":["1435-604X"],"issn-type":[{"value":"1435-604X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,14]]},"assertion":[{"value":"28 July 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This experiment complied with the principles of the Anhui Medical University Regulations for Animal Experiments and was approved by the Animal Experiment Ethics Committee (LLSC20220587).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"For this type of study informed consent is not required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"17"}}