{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T08:13:18Z","timestamp":1771402398574,"version":"3.50.1"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"DOI":"10.1007\/s10103-025-04388-w","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:15:18Z","timestamp":1741824918000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An ex vivo experimental study comparing the effects of the holmium: yttrium\u2013aluminum-garnet and thulium fiber lasers on testicular tissue"],"prefix":"10.1007","volume":"40","author":[{"given":"Mustafa","family":"Karaaslan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Yilmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melike","family":"Ordu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Emin","family":"Sirin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"key":"4388_CR1","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1097\/MOU.0000000000000815","volume":"306","author":"D Enikeev","year":"2020","unstructured":"Enikeev D, Traxer O, Taratkin M, Okhunov Z, Shariat S (2020) A review of thulium-fiber laser in stone lithotripsy and soft tissue surgery. Curr Opin Urol 306:853\u2013860","journal-title":"Curr Opin Urol"},{"key":"4388_CR2","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1002\/lsm.1900120402","volume":"124","author":"DE Johnson","year":"1992","unstructured":"Johnson DE, Cromeens DM, Price RE (1992) Use of the holmium:YAG laser in urology. Lasers Surg Med 124:353\u2013363","journal-title":"Lasers Surg Med"},{"key":"4388_CR3","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1007\/s00345-014-1395-1","volume":"334","author":"P Kronenberg","year":"2015","unstructured":"Kronenberg P, Traxer O (2015) Update on lasers in urology 2014: current assessment on holmium:yttrium-aluminum-garnet (Ho:YAG) laser lithotripter settings and laser fibers. World J Urol 334:463\u2013469","journal-title":"World J Urol"},{"key":"4388_CR4","unstructured":"Shvero A, Calio B, Humphreys MR, Das AK. HoLEP: the new gold standard for surgical treatment of benign prostatic hyperplasia. Can J Urol. 2021;28S2:6\u201310."},{"key":"4388_CR5","doi-asserted-by":"publisher","first-page":"2047","DOI":"10.1007\/s00345-022-04046-8","volume":"408","author":"D Enikeev","year":"2022","unstructured":"Enikeev D, Taratkin M, Babaevskaya D, Morozov A, Petov V, Sukhanov R et al (2022) Randomized prospective trial of the severity of irritative symptoms after HoLEP vs ThuFLEP. World J Urol 408:2047\u20132053","journal-title":"World J Urol"},{"key":"4388_CR6","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1111\/bju.15079","volume":"1261","author":"E Ventimiglia","year":"2020","unstructured":"Ventimiglia E, Doizi S, Kovalenko A, Andreeva V, Traxer O (2020) Effect of temporal pulse shape on urinary stone phantom retropulsion rate and ablation efficiency using holmium:YAG and super-pulse thulium fibre lasers. BJU Int 1261:159\u2013167","journal-title":"BJU Int"},{"key":"4388_CR7","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1586\/17434440.3.1.81","volume":"31","author":"NM Fried","year":"2006","unstructured":"Fried NM (2006) Therapeutic applications of lasers in urology: an update. Expert Rev Med Devices 31:81\u201394","journal-title":"Expert Rev Med Devices"},{"key":"4388_CR8","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/j.urology.2022.04.021","volume":"165","author":"A Iscaife","year":"2022","unstructured":"Iscaife A, Ribeiro Filho LA, Aparecido Pereira MW, Gallucci FP, Chade D, Murta CB et al (2022) Holmium Laser Resection of Large Bladder Tumors: Technique Description, Feasibility, and Histopathological Quality Analysis. Urology 165:373","journal-title":"Urology"},{"key":"4388_CR9","doi-asserted-by":"publisher","first-page":"3503","DOI":"10.1007\/s00345-021-03634-4","volume":"399","author":"S Huusmann","year":"2021","unstructured":"Huusmann S, Lafos M, Meyenburg I, Muschter R, Teichmann HO, Herrmann T (2021) Tissue effects of a newly developed diode pumped pulsed Thulium:YAG laser compared to continuous wave Thulium:YAG and pulsed Holmium:YAG laser. World J Urol 399:3503\u20133508","journal-title":"World J Urol"},{"key":"4388_CR10","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1007\/s10103-020-03189-7","volume":"371","author":"M Taratkin","year":"2022","unstructured":"Taratkin M, Kovalenko A, Laukhtina E, Paramonova N, Spivak L, Wachtendorf LJ et al (2022) Ex vivo study of Ho:YAG and thulium fiber lasers for soft tissue surgery: which laser for which case? Lasers Med Sci 371:149\u2013154","journal-title":"Lasers Med Sci"},{"key":"4388_CR11","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1089\/end.2020.0009","volume":"348","author":"B Becker","year":"2020","unstructured":"Becker B, Enikeev D, Netsch C, Gross AJ, Laukhtina E, Glybochko P et al (2020) Comparative Analysis of Vaporization and Coagulation Properties of a Hybrid Laser (Combination of a Thulium and Blue Diode Laser) Vs Thulium and Ho:YAG Lasers: Potential Applications in Endoscopic Enucleation of the Prostate. J Endourol 348:862\u2013867","journal-title":"J Endourol"},{"key":"4388_CR12","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1089\/end.2017.0835","volume":"323","author":"E Emiliani","year":"2018","unstructured":"Emiliani E, Talso M, Haddad M, Pouliquen C, Derman J, C\u00f4t\u00e9 JF et al (2018) The True Ablation Effect of Holmium YAG Laser on Soft Tissue. J Endourol 323:230\u2013235","journal-title":"J Endourol"},{"key":"4388_CR13","doi-asserted-by":"crossref","unstructured":"Shah HN, Arbelaez MCS, Shah K, Porto J, Chanamolu DK, Blachman-Braun R, et al. Histopathological assessment of depth of coagulation necrosis with Holmium, Moses, and Thulium fiber lasers in human prostate tissue. World J Urol. 2023.","DOI":"10.1007\/s00345-023-04617-3"},{"key":"4388_CR14","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1007\/s10103-018-2668-5","volume":"344","author":"DL Jiang","year":"2019","unstructured":"Jiang DL, Yang Z, Liu GX, Wu K, Fan J, Wu D et al (2019) A novel 450-nm blue laser system for surgical applications: efficacy of specific laser-tissue interactions in bladder soft tissue. Lasers Med Sci 344:807\u2013813","journal-title":"Lasers Med Sci"},{"key":"4388_CR15","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/978-1-4684-5913-5_3","volume":"286","author":"JM Bedford","year":"1991","unstructured":"Bedford JM (1991) Effects of elevated temperature on the epididymis and testis: experimental studies. Adv Exp Med Biol 286:19\u201332","journal-title":"Adv Exp Med Biol"},{"key":"4388_CR16","doi-asserted-by":"publisher","first-page":"2472805","DOI":"10.1155\/2017\/2472805","volume":"2017","author":"J Fedder","year":"2017","unstructured":"Fedder J, Marcussen N, Fedder MDK, Engvad B (2017) Testicular Damage following Testicular Sperm Retrieval: A Ram Model Study. Biomed Res Int 2017:2472805","journal-title":"Biomed Res Int"},{"key":"4388_CR17","doi-asserted-by":"crossref","unstructured":"Qu N, Itoh M, Sakabe K. Effects of Chemotherapy and Radiotherapy on Spermatogenesis: The Role of Testicular Immunology. Int J Mol Sci. 2019;204.","DOI":"10.3390\/ijms20040957"},{"key":"4388_CR18","doi-asserted-by":"crossref","unstructured":"Benazzo M, Canzi P, Mauramati S, Sovardi F, Occhini A, Maiorano E, et al. Transoral Robot-Assisted Surgery in Supraglottic and Oropharyngeal Squamous Cell Carcinoma: Laser Versus Monopolar Electrocautery. J Clin Med. 2019;812.","DOI":"10.3390\/jcm8122166"},{"key":"4388_CR19","doi-asserted-by":"publisher","first-page":"3091","DOI":"10.1007\/s00345-023-04555-0","volume":"4111","author":"ME \u015eirin","year":"2023","unstructured":"\u015eirin ME, Karaaslan M, Ordu M, Yilmaz M (2023) Effect of Ho:YAG laser on kidney tissue with Virtual Basket(\u2122) and Bubble Blast(\u2122) pulse modulation: an experimental ex vivo study. World J Urol 4111:3091\u20133095","journal-title":"World J Urol"},{"key":"4388_CR20","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1097\/00000478-198710000-00007","volume":"1110","author":"TD Trainer","year":"1987","unstructured":"Trainer TD (1987) Histology of the normal testis. Am J Surg Pathol 1110:797\u2013809","journal-title":"Am J Surg Pathol"},{"key":"4388_CR21","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.euros.2022.05.020","volume":"44","author":"O Traxer","year":"2022","unstructured":"Traxer O, Sierra A, Corrales M (2022) Which Is the Best Laser for Lithotripsy? Thulium Fiber Laser. Eur Urol Open Sci 44:15\u201317","journal-title":"Eur Urol Open Sci"},{"key":"4388_CR22","doi-asserted-by":"crossref","unstructured":"Kronenberg P, Traxer O. The laser of the future: reality and expectations about the new thulium fiber laser-a systematic review. Transl Androl Urol. 2019;8Suppl 4:S398-s417.","DOI":"10.21037\/tau.2019.08.01"},{"key":"4388_CR23","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1089\/end.2021.0263","volume":"362","author":"S Doizi","year":"2022","unstructured":"Doizi S, Germain T, Panthier F, Comp\u00e9rat E, Traxer O, Berthe L (2022) Comparison of Holmium:YAG and Thulium Fiber Lasers on Soft Tissue: An Ex Vivo Study. J Endourol 362:251\u2013258","journal-title":"J Endourol"},{"key":"4388_CR24","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1111\/bju.16447","volume":"1345","author":"S Kutchukian","year":"2024","unstructured":"Kutchukian S, Chicaud M, Berthe L, Coste F, Lapouge P, Alshehhi H et al (2024) Comparison of holmium:yttrium-aluminium-garnet (YAG), thulium fiber laser, and pulsed thulium:YAG lasers on soft tissue: an ex vivo study. BJU Int 1345:763\u2013772","journal-title":"BJU Int"},{"key":"4388_CR25","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1007\/s10103-024-04137-5","volume":"391","author":"M Emin Sirin","year":"2024","unstructured":"Emin Sirin M, Karaaslan M, Ordu M, Yilmaz M (2024) Comparison of the effects of Ho: YAG laser virtual Basket\u2122 pulse modulation and Thulium fiber laser on kidney tissue - an ex vivo experimental study. Lasers Med Sci 391:185","journal-title":"Lasers Med Sci"},{"key":"4388_CR26","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1002\/lsm.23158","volume":"525","author":"V Arkhipova","year":"2020","unstructured":"Arkhipova V, Enikeev M, Laukhtina E, Kurkov A, Andreeva V, Yaroslavsky I et al (2020) Ex vivo and animal study of the blue diode laser, Tm fiber laser, and their combination for laparoscopic partial nephrectomy. Lasers Surg Med 525:437\u2013448","journal-title":"Lasers Surg Med"},{"key":"4388_CR27","doi-asserted-by":"crossref","unstructured":"Patrikidou A, Cazzaniga W, Berney D, Boormans J, de Angst I, Di Nardo D, et al. European Association of Urology Guidelines on Testicular Cancer: 2023 Update. Eur Urol. 2023.","DOI":"10.1016\/j.eururo.2023.04.010"}],"container-title":["Lasers in Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-025-04388-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10103-025-04388-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-025-04388-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T07:20:16Z","timestamp":1771399216000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10103-025-04388-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,13]]},"references-count":27,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4388"],"URL":"https:\/\/doi.org\/10.1007\/s10103-025-04388-w","relation":{},"ISSN":["1435-604X"],"issn-type":[{"value":"1435-604X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,13]]},"assertion":[{"value":"6 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 March 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable for this section. The manuscript does not contain clinical studies or patient data. This article does not contain any studies with human subjects performed by the any of the authors. The authors did not perform any procedures on living humans or animals. Only fresh ex-vivo calf testicles were utilized in this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"138"}}