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The participants were divided into three groups: Group 1: SRP (control), Group 2: LANAP, and Group 3: LLLT. Clinical measurements, gingival crevicular fluid (GCF) samples, and standard periapical radiographs were obtained pre-treatment and at one- and three-month follow-ups. In GCF, interleukin-1beta (IL-1\u03b2), interleukin-10 (IL-10), and vascular endothelial growth factor (VEGF) were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In moderate (4\u20136\u00a0mm) and deep pockets (\u2265\u20097\u00a0mm), laser-treated groups showed a significant reduction in pocket depth (PD) and clinical attachment level (CAL) compared to the control group. However, there were no statistically significant differences in biochemical markers between the groups. Group 2 demonstrated significant bone filling compared to the control group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In deep pockets, laser-treated groups provide additional benefits to SRP. The application of LLLT positively affected recession (REC).<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Trial registration number:<\/jats:bold>\n                      NCT04694222\n                    <\/jats:p>\n                    <jats:p>\n                      <jats:bold>Date of registration:<\/jats:bold>\n                      01\/01\/2021\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10103-025-04457-0","type":"journal-article","created":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T21:49:54Z","timestamp":1745272194000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Evaluating efficacy of laser-assisted new attachment procedure and adjunctive low-level laser therapy in treating periodontitis: A single-blind randomized controlled clinical study"],"prefix":"10.1007","volume":"40","author":[{"given":"Fadime","family":"Kaya Dadas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selin","family":"Genc Kocaayan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Saglam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omer Faruk","family":"Dadas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serhat","family":"Koseoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,22]]},"reference":[{"key":"4457_CR1","unstructured":"Dommisch H, Kebschull M (2015) Chronic periodontitis. 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