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Patients were adequately informed of the aims, methods, institutional affiliations of the researchers, the anticipated benefits and potential risks of the study and the discomfort it may entail, post-study provisions and any other relevant aspects of the study. The patients were informed of the right to refuse to participate in the study or to withdraw consent to participate at any time without reprisal. Freely-given, informed consent to participate in the study was obtained from all of the participants.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human ethics and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"231"}}