{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T21:18:33Z","timestamp":1792531113605,"version":"4.5.0"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:00:00Z","timestamp":1760054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:00:00Z","timestamp":1760054400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100018778","name":"Al-Azhar University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100018778","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Acne vulgaris is a common inflammatory skin disorder with physical and psychosocial impact. Laser therapies offer targeted, non-pharmacologic treatment options. We aimed to compare the efficacy and safety of the 577-nm diode laser versus the 1064-nm Nd: YAG laser in treating inflammatory acne vulgaris. In this prospective, split-face randomized trial, 52 patients underwent three sessions of laser treatment at two-week intervals. One side of the face was treated with a 577-nm diode laser and the other with a 1064-nm Nd: YAG laser. Outcomes included inflammatory lesion counts, Acne Severity Index (ASI), patient satisfaction, and adverse effects. Both lasers significantly reduced inflammatory lesions (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), with no significant difference between groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&gt;\u20090.05). Excellent ASI response was observed in 26.9% (diode) and 28.8% (Nd: YAG) treated sides. Satisfaction scores were comparable (2.5\u2009\u00b1\u20090.6 vs. 2.6\u2009\u00b1\u20090.5;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.59). Adverse events were mild and transient, with no serious complications. The 577-nm diode and 1064-nm Nd: YAG lasers are equally effective and well-tolerated for inflammatory acne, offering safe alternatives to conventional therapies.\n                  <\/jats:p>","DOI":"10.1007\/s10103-025-04654-x","type":"journal-article","created":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T08:12:50Z","timestamp":1760083970000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparative efficacy and safety of 577-nm diode laser versus 1064-nm Nd: YAG laser for inflammatory acne vulgaris: a split-face randomized study"],"prefix":"10.1007","volume":"40","author":[{"given":"Essamelden M.","family":"Mohamed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hazem L.","family":"Abdel-Aleem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghadeer M. H.","family":"Elazab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud A.","family":"Rageh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,10]]},"reference":[{"issue":"3","key":"4654_CR1","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1111\/bjd.12149","volume":"168","author":"K Bhate","year":"2013","unstructured":"Bhate K, Williams HC (2013) Epidemiology of acne vulgaris. Br J Dermatol 168(3):474\u2013485. https:\/\/doi.org\/10.1111\/bjd.12149","journal-title":"Br J Dermatol"},{"key":"4654_CR2","doi-asserted-by":"publisher","unstructured":"Dreno B, Pecastaings S, Corvec S, Veraldi S, Khammari A, Roques C (2018) Cutibacterium acnes (Propionibacterium acnes) and acne vulgaris: a brief look at the latest updates. 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