{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T15:46:14Z","timestamp":1790005574228,"version":"4.0.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"DOI":"10.1007\/s10103-026-04799-3","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T13:59:35Z","timestamp":1771595975000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A systematic review of therapeutic procedures for the treatment of morphea and systemic sclerosis"],"prefix":"10.1007","volume":"41","author":[{"given":"Alireza","family":"Jafarzadeh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amirhossein","family":"Leisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azadeh","family":"Goodarzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,20]]},"reference":[{"issue":"4","key":"4799_CR1","first-page":"757","volume":"65","author":"SC Li","year":"2018","unstructured":"Li SC (2018) Scleroderma in children and adolescents: localized scleroderma and systemic sclerosis. Pediatr Clin 65(4):757\u2013781","journal-title":"Pediatr Clin"},{"issue":"10103","key":"4799_CR2","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1016\/S0140-6736(17)30933-9","volume":"390","author":"CP Denton","year":"2017","unstructured":"Denton CP, Khanna D (2017) Systemic sclerosis. Lancet 390(10103):1685\u20131699","journal-title":"Lancet"},{"issue":"3","key":"4799_CR3","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1002\/kjm2.12505","volume":"38","author":"AH Rosendahl","year":"2022","unstructured":"Rosendahl AH, Sch\u00f6nborn K, Krieg T (2022) Pathophysiology of systemic sclerosis (scleroderma). Kaohsiung J Med Sci 38(3):187\u2013195","journal-title":"Kaohsiung J Med Sci"},{"issue":"9","key":"4799_CR4","doi-asserted-by":"publisher","first-page":"530","DOI":"10.12968\/hmed.2019.80.9.530","volume":"80","author":"M Hughes","year":"2019","unstructured":"Hughes M, Herrick AL (2019) Systemic sclerosis. Br J Hosp Med (Lond) 80(9):530\u2013536","journal-title":"Br J Hosp Med (Lond)"},{"issue":"10","key":"4799_CR5","doi-asserted-by":"publisher","first-page":"2738","DOI":"10.3390\/jcm13102738","volume":"13","author":"R Foti","year":"2024","unstructured":"Foti R, Zeppieri M, Foti R, Visalli E, Amato G, Amato R, Dammino E, D\u2019Esposito F, Gagliano C (2024) Retinal vascular abnormalities and clinical parameters in systemic sclerosis. J Clin Med 13(10):2738","journal-title":"J Clin Med"},{"issue":"2","key":"4799_CR6","doi-asserted-by":"publisher","first-page":"208","DOI":"10.23736\/S0392-0488.18.05922-9","volume":"153","author":"F Rongioletti","year":"2018","unstructured":"Rongioletti F, Ferreli C, Atzori L, Bottoni U, Soda G (2018) Scleroderma with an update about clinico-pathological correlation. Ital J Dermatol Venereol 153(2):208\u201315","journal-title":"Ital J Dermatol Venereol"},{"issue":"2","key":"4799_CR7","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1111\/ddg.12724","volume":"14","author":"A Kreuter","year":"2016","unstructured":"Kreuter A, Krieg T, Worm M, Wenzel J, Moinzadeh P, Kuhn A et al (2016) German guidelines for the diagnosis and therapy of localized scleroderma. JDDG J Dtsch Dermatol Ges 14(2):199\u2013216","journal-title":"JDDG J Dtsch Dermatol Ges"},{"key":"4799_CR8","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2023.1108623","volume":"10","author":"C Papara","year":"2023","unstructured":"Papara C, De Luca DA, Bieber K, Vorobyev A, Ludwig RJ (2023) Morphea: the 2023 update. Front Med (Lausanne) 10:1108623","journal-title":"Front Med (Lausanne)"},{"issue":"2","key":"4799_CR9","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1016\/j.jaad.2019.12.081","volume":"83","author":"A Creadore","year":"2020","unstructured":"Creadore A, Watchmaker J, Maymone MBC, Pappas L, Lam C, Vashi NA (2020) Cosmetic treatment in patients with autoimmune connective tissue diseases: best practices for patients with morphea\/systemic sclerosis. J Am Acad Dermatol 83(2):315\u2013341","journal-title":"J Am Acad Dermatol"},{"issue":"3","key":"4799_CR10","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1007\/s12016-017-8625-4","volume":"53","author":"C Ferreli","year":"2017","unstructured":"Ferreli C, Gasparini G, Parodi A, Cozzani E, Rongioletti F, Atzori L (2017) Cutaneous manifestations of scleroderma and scleroderma-like disorders: a comprehensive review. Clin Rev Allergy Immunol 53(3):306\u2013336","journal-title":"Clin Rev Allergy Immunol"},{"issue":"5","key":"4799_CR11","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1177\/12034754241260018","volume":"28","author":"S Ghazal","year":"2024","unstructured":"Ghazal S, Zhang Huang H, Gabrielli S, Khoury L, Pehr K, Veilleux M et al (2024) Localized scleroderma burden: a scoping review focusing on the health-related quality of life, mental health, and productivity. J Cutan Med Surg 28(5):487\u20138","journal-title":"J Cutan Med Surg"},{"issue":"11","key":"4799_CR12","doi-asserted-by":"publisher","DOI":"10.1002\/hsr2.70180","volume":"7","author":"MA Jafari","year":"2024","unstructured":"Jafari MA, Bazgir G, Hosseini-Baharanchi FS, Jafarzadeh A, Goodarzi A (2024) Efficacy and safety of laser therapy and phototherapy in cicatricial and noncicatricial alopecia: a systematic review study. Health Sci Rep 7(11):e70180","journal-title":"Health Sci Rep"},{"issue":"1","key":"4799_CR13","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1007\/s10103-025-04429-4","volume":"40","author":"A Jafarzadeh","year":"2025","unstructured":"Jafarzadeh A, Heidari S, Omid R, Goodarzi A (2025) Systematic review of vascular lasers for the treatment of inflammatory active acne vulgaris. Lasers Med Sci 40(1):168","journal-title":"Lasers Med Sci"},{"issue":"4","key":"4799_CR14","doi-asserted-by":"publisher","first-page":"524","DOI":"10.5114\/ada.2020.98239","volume":"37","author":"M Zbiciak-Nylec","year":"2020","unstructured":"Zbiciak-Nylec M, Wcis\u0142o-Dziadecka D, Brzezi\u00f1ska-Wcis\u0142o L (2020) Factors affecting the concentration of soluble tumour necrosis factor-\u03b1 receptor type i in the blood serum of patients with localized scleroderma. Postepy Dermatol Alergol 37(4):524\u2013530","journal-title":"Postepy Dermatol Alergol"},{"issue":"6","key":"4799_CR15","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1111\/phpp.12786","volume":"38","author":"L Tognetti","year":"2022","unstructured":"Tognetti L, Marrocco C, Carraro A, Guerrini G, Mariotti G, Cinotti E, Rubegni P (2022) Clinical and laboratory characterization of patients with localized scleroderma and response to UVA-1 phototherapy: in vivo and in vitro skin models. Photodermatol Photoimmunol Photomed 38(6):531\u2013540","journal-title":"Photodermatol Photoimmunol Photomed"},{"issue":"23","key":"4799_CR16","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222312681","volume":"22","author":"DN Dorst","year":"2021","unstructured":"Dorst DN, van Caam APM, Vitters EL, Walgreen B, Helsen MMA, Klein C, Gudi S, Wubs T, Kumari J, Vonk MC, van der Kraan PM, Koenders MI (2021) Fibroblast activation protein targeted photodynamic therapy selectively kills activated skin fibroblasts from systemic sclerosis patients and prevents tissue contraction. Int J Mol Sci 22(23):12681","journal-title":"Int J Mol Sci"},{"issue":"2","key":"4799_CR17","doi-asserted-by":"publisher","first-page":"162","DOI":"10.4103\/ijdvl.IJDVL_751_17","volume":"86","author":"BKY Chia","year":"2020","unstructured":"Chia BKY, Chia GSZ, Tan EST, Tan VWD, Chong WS (2020) Ultraviolet-A1 phototherapy in Asian skin: a review of 159 cases in Singapore. Indian J Dermatol Venereol Leprol 86(2):162\u2013168","journal-title":"Indian J Dermatol Venereol Leprol"},{"issue":"3","key":"4799_CR18","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1080\/09546634.2018.1484875","volume":"30","author":"M Hughes","year":"2019","unstructured":"Hughes M, Moore T, Manning J, Wilkinson J, Watson S, Samraj P, Dinsdale G, Roberts C, Rhodes LE, Herrick AL, Murray A (2019) A feasibility study of a novel low-level light therapy for digital ulcers in systemic sclerosis. J Dermatolog Treat 30(3):251\u2013257","journal-title":"J Dermatolog Treat"},{"issue":"1","key":"4799_CR19","doi-asserted-by":"publisher","first-page":"60","DOI":"10.4103\/0378-6323.182805","volume":"83","author":"SK Attili","year":"2017","unstructured":"Attili SK, Dawe RS, Ibbotson SH (2017) Ultraviolet A1 phototherapy: one center\u2019s experience. Indian J Dermatol Venereol Leprol 83(1):60\u201365","journal-title":"Indian J Dermatol Venereol Leprol"},{"issue":"3","key":"4799_CR20","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.jaad.2013.10.018","volume":"70","author":"R Vasquez","year":"2014","unstructured":"Vasquez R, Jabbar A, Khan F, Buethe D, Ahn C, Jacobe H (2014) Recurrence of morphea after successful ultraviolet A1 phototherapy: a cohort study. J Am Acad Dermatol 70(3):481\u2013488","journal-title":"J Am Acad Dermatol"},{"issue":"4","key":"4799_CR21","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1159\/000329024","volume":"222","author":"V von Felbert","year":"2011","unstructured":"von Felbert V, Kernland-Lang K, Hoffmann G, Wienert V, Simon D, Hunziker T (2011) Irradiation with water-filtered infrared A plus visible light improves cutaneous scleroderma lesions in a series of cases. Dermatology 222(4):347\u201357","journal-title":"Dermatology"},{"issue":"4","key":"4799_CR22","doi-asserted-by":"publisher","first-page":"757","DOI":"10.5114\/ada.2021.108437","volume":"39","author":"A Malewska-Wo\u017aniak","year":"2022","unstructured":"Malewska-Wo\u017aniak A, Osmola-Ma\u00f1kowska A, Adamski Z (2022) Effectiveness of PUVA vs. UVA1 phototherapy in the treatment of morphea patients. Adv Dermatol Allergol 39(4):757\u2013761","journal-title":"Adv Dermatol Allergol"},{"issue":"8","key":"4799_CR23","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1111\/j.1365-4632.2010.04843.x","volume":"50","author":"O Su","year":"2011","unstructured":"Su O, Onsun N, Onay HK, Erdemoglu Y, Ozkaya DB, Cebeci F, Somay A (2011) Effectiveness of medium-dose ultraviolet A1 phototherapy in localized scleroderma. Int J Dermatol 50(8):1006\u20131013","journal-title":"Int J Dermatol"},{"issue":"2","key":"4799_CR24","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1111\/j.1365-2133.2009.09438.x","volume":"162","author":"C Andres","year":"2010","unstructured":"Andres C, Kollmar A, Mempel M, Hein R, Ring J, Eberlein B (2010) Successful ultraviolet A1 phototherapy in the treatment of localized scleroderma: a retrospective and prospective study. Br J Dermatol 162(2):445\u2013447","journal-title":"Br J Dermatol"},{"issue":"6","key":"4799_CR25","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1111\/phpp.12185","volume":"31","author":"KL Connolly","year":"2015","unstructured":"Connolly KL, Griffith JL, McEvoy M, Lim HW (2015) Ultraviolet A1 phototherapy beyond morphea: experience in 83 patients. Photodermatol Photoimmunol Photomed 31(6):289\u2013295","journal-title":"Photodermatol Photoimmunol Photomed"},{"issue":"1","key":"4799_CR26","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1007\/s00403-024-03674-x","volume":"317","author":"MM El-Shahawy","year":"2025","unstructured":"El-Shahawy MM, Farag AS, El-Khalawany MA, Pessar DA (2025) Comparative study between fractional CO2 laser (10,600 nm) and microneedling in treatment of morphea: dermoscopic and histopathological evaluation. Arch Dermatol Res 317(1):276","journal-title":"Arch Dermatol Res"},{"issue":"11","key":"4799_CR27","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics14112261","volume":"14","author":"Q Guo","year":"2022","unstructured":"Guo Q, He M, Cen J, Huang D, Hao S, Tang Z, Xiong H (2022) Efficacy and safety of ablative fractional laser-assisted delivery of methotrexate in adults with localized scleroderma: a randomized and controlled clinical trial. Pharmaceutics 14(11):2261","journal-title":"Pharmaceutics"},{"issue":"8","key":"4799_CR28","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1007\/s10103-016-2041-5","volume":"31","author":"SM Shalaby","year":"2016","unstructured":"Shalaby SM, Bosseila M, Fawzy MM, Abdel Halim DM, Sayed SS, Allam RS (2016) Fractional carbon dioxide laser versus low-dose UVA-1 phototherapy for treatment of localized scleroderma: a clinical and immunohistochemical randomized controlled study. Lasers Med Sci 31(8):1707\u20131715","journal-title":"Lasers Med Sci"},{"issue":"4","key":"4799_CR29","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1001\/jamadermatol.2023.5908","volume":"160","author":"J Liu","year":"2024","unstructured":"Liu J, Wang J, Zhang Q, Lu F, Cai J (2024) Clinical, histologic, and transcriptomic evaluation of sequential fat grafting for morphea: a nonrandomized controlled trial. JAMA Dermatol 160(4):425\u2013433","journal-title":"JAMA Dermatol"},{"issue":"8","key":"4799_CR30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0289594","volume":"18","author":"M Iglesias","year":"2023","unstructured":"Iglesias M, Torre-Villalvazo I, Butr\u00f3n-Gandarillas P, Rodr\u00edguez-Reyna TS, Torre-Anaya EA, Guevara-Cruz M, Flores-Ch\u00e1irez MA, L\u00f3pez-Contreras DB, L\u00f3pez-S\u00e1nchez JY, Ruiz-Betanzos \u00c1J, M\u00e9ndez L\u00f3pez AL, Rubio-Gutierrez C, T\u00e9llez-Pallares F, Nario-Chaidez F (2023) Adipose derived stromal vascular fraction and fat graft for treating the hands of patients with systemic sclerosis. A randomized clinical trial. PLoS One 18(8):e0289594","journal-title":"PLoS One"},{"issue":"1","key":"4799_CR31","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/s10067-021-05900-7","volume":"41","author":"S Shenavandeh","year":"2022","unstructured":"Shenavandeh S, Sepaskhah M, Dehghani S, Nazarinia M (2022) A 4-week comparison of capillaroscopy changes, healing effect, and cost-effectiveness of botulinum toxin-A vs prostaglandin analog infusion in refractory digital ulcers in systemic sclerosis. Clin Rheumatol 41(1):95\u2013104","journal-title":"Clin Rheumatol"},{"issue":"4","key":"4799_CR32","first-page":"E453","volume":"24","author":"A Elawamy","year":"2021","unstructured":"Elawamy A, Hassanien M, Talaat EA, Ali AM, Roushdy ASI, Kamel EZ (2021) Intra-carpal injection of ozone versus methylprednisolone in carpal tunnel syndrome of systemic sclerosis patients: a randomized single-blind clinical trial. Pain Physician 24(4):E453\u2013E458","journal-title":"Pain Physician"},{"key":"4799_CR33","unstructured":"Lautenbach G, Dobrota R, Mihai C, Distler O, Calcagni M, Maurer B Evaluation of botulinum toxin A injections for the treatment of refractory chronic digital ulcers in patients with systemic sclerosis. Clin Exp Rheumatol 2020 May-Jun;38 Suppl 125(3):154\u2013160. Epub 2020 Apr 15."},{"issue":"1","key":"4799_CR34","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1186\/s13075-019-2062-0","volume":"21","author":"R Pirrello","year":"2019","unstructured":"Pirrello R, Verro B, Grasso G, Ruscitti P, Cordova A, Giacomelli R, Ciccia F, Guggino G (2019) Hyaluronic acid and platelet-rich plasma, a new therapeutic alternative for scleroderma patients: a prospective open-label study. Arthritis Res Ther 21(1):286","journal-title":"Arthritis Res Ther"},{"issue":"1","key":"4799_CR35","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-017-0690-3","volume":"8","author":"F Virz\u00ec","year":"2017","unstructured":"Virz\u00ec F, Bianca P, Giammona A, Apuzzo T, Di Franco S, Mangiapane LR, Colorito ML, Catalano D, Scavo E, Nicotra A, Benfante A, Pistone G, Caputo V, Dieli F, Pirrello R, Stassi G (2017) Combined platelet-rich plasma and lipofilling treatment provides great improvement in facial skin-induced lesion regeneration for scleroderma patients. Stem Cell Res Ther 8(1):236","journal-title":"Stem Cell Res Ther"},{"issue":"7","key":"4799_CR36","doi-asserted-by":"publisher","first-page":"843","DOI":"10.2340\/00015555-2665","volume":"97","author":"SI Motegi","year":"2017","unstructured":"Motegi SI, Uehara A, Yamada K, Sekiguchi A, Fujiwara C, Toki S, Date Y, Nakamura T, Ishikawa O (2017) Efficacy of botulinum toxin B injection for raynaud\u2019s phenomenon and digital ulcers in patients with systemic sclerosis. Acta Derm Venereol 97(7):843\u2013850","journal-title":"Acta Derm Venereol"},{"issue":"8","key":"4799_CR37","doi-asserted-by":"publisher","first-page":"1661","DOI":"10.1002\/art.40123","volume":"69","author":"RJ Bello","year":"2017","unstructured":"Bello RJ, Cooney CM, Melamed E, Follmar K, Yenokyan G, Leatherman G, Shah AA, Wigley FM, Hummers LK, Lifchez SD (2017) The therapeutic efficacy of botulinum toxin in treating scleroderma-associated raynaud\u2019s phenomenon: a randomized, double-blind, placebo-controlled clinical trial. Arthritis Rheumatol 69(8):1661\u20131669","journal-title":"Arthritis Rheumatol"},{"issue":"12","key":"4799_CR38","doi-asserted-by":"publisher","first-page":"2175","DOI":"10.1136\/annrheumdis-2014-205681","volume":"74","author":"B Granel","year":"2015","unstructured":"Granel B, Daumas A, Jouve E, Harl\u00e9 JR, Nguyen PS, Chabannon C, Colavolpe N, Reynier JC, Truillet R, Mallet S, Baiada A, Casanova D, Giraudo L, Arnaud L, Veran J, Sabatier F, Magalon G (2015) Safety, tolerability and potential efficacy of injection of autologous adipose-derived stromal vascular fraction in the fingers of patients with systemic sclerosis: an open-label phase I trial. Ann Rheum Dis 74(12):2175\u20132182","journal-title":"Ann Rheum Dis"},{"issue":"6","key":"4799_CR39","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1007\/s10067-010-1653-6","volume":"30","author":"SL DeLea","year":"2011","unstructured":"DeLea SL, Chavez-Chiang NR, Poole JL, Norton HE, Sibbitt WL Jr, Bankhurst AD (2011) Sonographically guided hydrodissection and corticosteroid injection for scleroderma hand. Clin Rheumatol 30(6):805\u201313","journal-title":"Clin Rheumatol"},{"issue":"6","key":"4799_CR40","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1007\/s13555-020-00438-z","volume":"10","author":"A Owczarczyk-Saczonek","year":"2020","unstructured":"Owczarczyk-Saczonek A, Kasprowicz-Furma\u0144czyk M, Kruszewska A, Krajewska-W\u0142odarczyk M, Bechtold A, Klimek P, Placek W (2020) The correction of facial morphea lesions by hyaluronic acid: a case series and literature review. Dermatol Ther 10(6):1423\u20131434","journal-title":"Dermatol Ther"},{"issue":"12","key":"4799_CR41","doi-asserted-by":"publisher","first-page":"2098","DOI":"10.3390\/sym12122098","volume":"12","author":"C Baserga","year":"2020","unstructured":"Baserga C, Cappella A, Gibelli DM, Sacco R, Dolci C, Cullati F, Giann\u00ec AB, Sforza C (2020) Efficacy of autologous fat grafting in restoring facial symmetry in linear morphea-associated lesions. Symmetry 12(12):2098","journal-title":"Symmetry"},{"issue":"1","key":"4799_CR42","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1007\/s10103-025-04382-2","volume":"40","author":"M Ghassemi","year":"2025","unstructured":"Ghassemi M, Mireshghollah P, Jafarzadeh A, Seirafianpour F, Behrangi E, Montazeri Namin S, Khosravi M, Goodarzi A (2025) Evaluating the combination and comparison of ablative fractional lasers (CO2, Erbium-YAG) with pulsed dye laser (PDL) for treating hypertrophic scars: a systematic review. Lasers Med Sci 40(1):129","journal-title":"Lasers Med Sci"},{"key":"4799_CR43","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.2147\/CCID.S356641","volume":"15","author":"J Sharad","year":"2022","unstructured":"Sharad J (2022) Hyaluronic acid filler injection for localized scleroderma - case report and review of literature on filler injections for localized scleroderma. Clin Cosmet Investig Dermatol 15:1627\u20131637","journal-title":"Clin Cosmet Investig Dermatol"},{"issue":"1","key":"4799_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10103-025-04338-6","volume":"40","author":"N Atefi","year":"2025","unstructured":"Atefi N, Jafari MA, Roohaninasab M, Dehghani A, Jafarzadeh A, Peighambari SB, Peighambari A, Goodarzi A (2025) Evaluating the effectiveness and safety of pulsed dye laser alone, the combination of pulsed dye laser and botulinum toxin type A, and the combination of pulsed dye laser and triamcinolone injection in the treatment of hypertrophic and keloid scars: a three-arm randomized controlled clinical trial. Lasers Med Sci 40(1):1\u201311","journal-title":"Lasers Med Sci"}],"container-title":["Lasers in Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-026-04799-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10103-026-04799-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-026-04799-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T14:04:50Z","timestamp":1771596290000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10103-026-04799-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,20]]},"references-count":44,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4799"],"URL":"https:\/\/doi.org\/10.1007\/s10103-026-04799-3","relation":{},"ISSN":["1435-604X"],"issn-type":[{"value":"1435-604X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,20]]},"assertion":[{"value":"18 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The Ethics Committee has waived the requirement for ethical approval, as this article is based on previously conducted studies and does not contain any new studies involving human participants or animals conducted by any of the authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}}],"article-number":"34"}}