{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T23:12:47Z","timestamp":1784329967848,"version":"3.55.0"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100020832","name":"Universidade De Passo Fundo","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100020832","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To illustrate the clinical use and feasibility of the REVEAL\u2122 fluorescence loupe as an adjunctive tool in the chairside assessment of inflammatory, potentially malignant, and malignant oral lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Five patients with oral lesions were clinically examined under natural light and with the REVEAL\u2122 loupe. When indicated, biopsy and histopathological analysis were performed<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Inflammatory lesions exhibited a bright and homogeneous red autofluorescence pattern. Actinic cheilitis demonstrated heterogeneous brownish autofluorescence with whitish areas. Squamous cell carcinomas did not show significant autofluorescence contrast. The presence of biofilm was highlighted by a distinct orange signal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The REVEAL\u2122 loupe may support the clinical assessment of oral lesions by illustrating autofluorescence patterns associated with underlying tissue changes. However, its use should be considered complementary to biopsy, not a diagnostic substitute.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10103-026-04861-0","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T07:46:18Z","timestamp":1774251978000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical application of the REVEAL\u2122 fluorescence loupe in oral lesion assessment: a five-case clinical note"],"prefix":"10.1007","volume":"41","author":[{"given":"Matheus","family":"Albino Souza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Let\u00edcia","family":"Copatti Dogenski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Chitolina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduarda","family":"Lunelli Ferrari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisele","family":"Rovani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liviu","family":"Steier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Ant\u00f4nio","family":"Poli de Figueiredo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Paulo","family":"De Carli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,23]]},"reference":[{"issue":"6","key":"4861_CR1","doi-asserted-by":"publisher","first-page":"951","DOI":"10.3390\/diagnostics11060951","volume":"11","author":"V Shavlokhova","year":"2021","unstructured":"Shavlokhova V, Flechtenmacher C, Sandhu S et al (2021) Feasibility and implementation of ex vivo fluorescence confocal microscopy for diagnosis of oral leukoplakia: preliminary study. 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