{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T10:07:08Z","timestamp":1792404428655,"version":"4.4.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Purpose: Scars may lead to pain, pruritus, functional impairment, and cosmetic concern despite standard therapies. Photobiomodulation (PBM) delivered by light-emitting-diode (LED) or low-level laser therapy (LLLT) has emerged as a non-invasive option to modulate scar remodeling. However, available data derives from small, heterogenous studies. This scoping review evaluates whether red and near-infrared PBM improves clinical outcomes in burn, hypertrophic, and post-surgical scars and summarizes treatment parameters used. Methods: PubMed, Embase, and MEDLINE were searched through October 2025 for randomized or prospective clinical studies in which red (633-670nm) or near-infrared (808-830nm) LED or LLLT was used as monotherapy or where its contribution could be independently assessed. Seven studies (n=297) met inclusion criteria. Data on scar type, wavelength, fluence, regimen, outcomes, and adverse events were extracted. Results: Red LED improved VSS scores, pigmentation, and thickness in pediatric and adult burn scars, with greater benefits observed in scars\u2009&lt;\u200912 months. In post-surgical scars, red LED reduced induration and improved POSAS scores, with a biphasic dose-response favoring moderate fluence levels. Near-infrared PBM improved color and elasticity in hypertrophic scars and reduced thickness, malleability, pain, and pruritus following hernia repair, thyroidectomy, and blepharoplasty. Across studies, PBM was well tolerated; transient erythema and warmth were most common, with rare blistering at higher fluences. Conclusion: Red and near-infrared PBM appears to be a safe, non-invasive adjunct to standard scar management, particularly for early burn and post-operative scars. Larger controlled trials are needed to define optimal wavelength, fluence, timing, and treatment parameters across diverse scar phenotypes and skin phototypes. Clinical Trial Registration: Not applicable.<\/jats:p>","DOI":"10.1007\/s10103-026-04875-8","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:31:00Z","timestamp":1776990660000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Red and near-infrared photobiomodulation for burn, hypertrophic, and post-surgical scars: a scoping review of clinical trials"],"prefix":"10.1007","volume":"41","author":[{"given":"Simonetta I.","family":"Gaumond","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilee M.","family":"Dreifus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amisha","family":"Mittal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariel E.","family":"Eber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"issue":"3","key":"4875_CR1","doi-asserted-by":"publisher","first-page":"e13272","DOI":"10.1111\/srt.13272","volume":"29","author":"A Lubczy\u0144ska","year":"2023","unstructured":"Lubczy\u0144ska A, Garncarczyk A, Wcis\u0142o-Dziadecka D (2023) Effectiveness of various methods of manual scar therapy. 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