{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T10:03:45Z","timestamp":1789553025303,"version":"build-2803163510"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"DOI":"10.1007\/s10103-026-05020-1","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T09:16:24Z","timestamp":1789550184000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Single-session extraoral photobiomodulation reduces early postoperative pain but not edema or trismus after impacted mandibular third molar extraction: a randomized controlled trial"],"prefix":"10.1007","volume":"41","author":[{"given":"Ahmet","family":"Ana\u00e7","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bozkurt Kubi\u0307lay","family":"I\u015f\u0131k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeynep Asude","family":"Bozk\u0131r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"5020_CR1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-91920-7","volume-title":"Peterson\u2019s principles of oral and Maxillofacial Surgery","author":"M Miloro","year":"2022","unstructured":"Miloro M, Ghali GE, Larsen PE, Waite P (2022) Peterson\u2019s principles of oral and Maxillofacial Surgery. Springer, Berlin, Germany"},{"key":"5020_CR2","unstructured":"Osunde O, Adebola R, Omeje U (2011) Management of inflammatory complications in third molar surgery: a review of the literature. African health sciences"},{"key":"5020_CR3","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1089\/pho.2016.4252","volume":"35","author":"SA Kahraman","year":"2017","unstructured":"Kahraman SA, Cetiner S, Strauss RA (2017) The effects of transcutaneous and intraoral low-level laser therapy after extraction of lower third molars: a randomized single blind, placebo controlled dual-center study. Photomed Laser Surg 35:401\u2013407","journal-title":"Photomed Laser Surg"},{"key":"5020_CR4","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1007\/s10103-012-1174-4","volume":"28","author":"M Ferrante","year":"2013","unstructured":"Ferrante M, Petrini M, Trentini P et al (2013) Effect of low-level laser therapy after extraction of impacted lower third molars. Lasers Med Sci 28:845\u2013849","journal-title":"Lasers Med Sci"},{"key":"5020_CR5","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1007\/s10103-011-0936-8","volume":"27","author":"M L\u00f3pez-Ram\u00edrez","year":"2012","unstructured":"L\u00f3pez-Ram\u00edrez M, V\u00edlchez-P\u00e9rez MA, Gargallo-Albiol J et al (2012) Efficacy of low-level laser therapy in the management of pain, facial swelling, and postoperative trismus after a lower third molar extraction. A preliminary study. Lasers Med Sci 27:559\u2013566","journal-title":"Lasers Med Sci"},{"key":"5020_CR6","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1089\/pho.2006.24.158","volume":"24","author":"J Bjordal","year":"2006","unstructured":"Bjordal J, Johnson M, Iversen V et al (2006) Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials. Photomed Laser Surg 24:158\u2013168","journal-title":"Photomed Laser Surg"},{"key":"5020_CR7","doi-asserted-by":"publisher","first-page":"313e1","DOI":"10.1016\/j.joms.2020.09.018","volume":"79","author":"F Domah","year":"2021","unstructured":"Domah F, Shah R, Nurmatov UB, Tagiyeva N (2021) The use of low-level laser therapy to reduce postoperative morbidity after third molar surgery: A systematic review and meta-analysis. J Oral Maxillofac Surg 79:313e1\u2013313e19","journal-title":"J Oral Maxillofac Surg"},{"key":"5020_CR8","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1016\/j.jcms.2021.06.006","volume":"49","author":"FJ Duarte de Oliveira","year":"2021","unstructured":"Duarte de Oliveira FJ, Brasil GMLC, Ara\u00fajo Soares GP et al (2021) Use of low-level laser therapy to reduce postoperative pain, edema, and trismus following third molar surgery: A systematic review and meta-analysis. J Craniomaxillofac Surg 49:1088\u20131096","journal-title":"J Craniomaxillofac Surg"},{"key":"5020_CR9","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1016\/j.joms.2025.05.010","volume":"83","author":"A P\u00e9rez","year":"2025","unstructured":"P\u00e9rez A, Rujano-Salinas A, Bennett L et al (2025) Effect of Photobiomodulation on the Control of Edema and Pain After Third Molar Surgery: Double-Blinded Randomized Clinical Trial. J Oral Maxillofac Surg 83:1122\u20131131","journal-title":"J Oral Maxillofac Surg"},{"key":"5020_CR10","doi-asserted-by":"crossref","unstructured":"Giovannacci I, Romeo U, Spadari F et al (2025) An italian multicenter triple-blind randomized controlled trial on photobiomodulation after third molar extraction (BIOSTOTT). A study of italian society for laser in dentistry (SILO). Med Oral Patol Oral Cir Bucal 0\u20130","DOI":"10.4317\/medoral.27834"},{"key":"5020_CR11","doi-asserted-by":"publisher","first-page":"5210","DOI":"10.3390\/jcm14155210","volume":"14","author":"L Mauriello","year":"2025","unstructured":"Mauriello L, Cuozzo A, Pezzella V et al (2025) Effects of photobiomodulation therapy (PBMT) in the management of postoperative pain after third lower molar extraction: A narrative review. J Clin Med 14:5210","journal-title":"J Clin Med"},{"key":"5020_CR12","doi-asserted-by":"publisher","first-page":"c332","DOI":"10.1136\/bmj.c332","volume":"340","author":"KF Schulz","year":"2010","unstructured":"Schulz KF, Altman DG, Moher D, CONSORT Group (2010) CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. BMJ 340:c332","journal-title":"BMJ"},{"key":"5020_CR13","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1186\/s12903-017-0371-8","volume":"17","author":"U G\u00fcl\u015fen","year":"2017","unstructured":"G\u00fcl\u015fen U, \u015eent\u00fcrk MF (2017) Effect of platelet rich fibrin on edema and pain following third molar surgery: a split mouth control study. BMC Oral Health 17:79","journal-title":"BMC Oral Health"},{"key":"5020_CR14","doi-asserted-by":"publisher","first-page":"1322e1","DOI":"10.1016\/j.joms.2016.02.030","volume":"74","author":"M Eshghpour","year":"2016","unstructured":"Eshghpour M, Ahrari F, Takallu M (2016) Is Low-Level Laser Therapy Effective in the Management of Pain and Swelling After Mandibular Third Molar Surgery? J Oral Maxillofac Surg 74:1322e1\u20131322e8","journal-title":"J Oral Maxillofac Surg"},{"key":"5020_CR15","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1177\/0022034511399918","volume":"90","author":"L Sischo","year":"2011","unstructured":"Sischo L, Broder HL (2011) Oral health-related quality of life: what, why, how, and future implications. J Dent Res 90:1264\u20131270","journal-title":"J Dent Res"},{"key":"5020_CR16","doi-asserted-by":"publisher","first-page":"14","DOI":"10.4103\/ams.ams_247_23","volume":"15","author":"M Jha","year":"2025","unstructured":"Jha M, Marimallappa TR, Kumar RM et al (2025) Efficacy of Low-level Laser Therapy in Minimising Morbidity Associated with Removal of Impacted Mandibular Third Molar - A Comparative Study. Ann Maxillofac Surg 15:14\u201318","journal-title":"Ann Maxillofac Surg"},{"key":"5020_CR17","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1016\/j.joms.2025.03.017","volume":"83","author":"E Sekerci","year":"2025","unstructured":"Sekerci E, Schiefersteiner M, Wiedemeier D, Valdec S (2025) Is low-level laser treatment effective in reducing pain, swelling, and trismus after removing impacted maxillary and mandibular third molars? J Oral Maxillofac Surg 83:874\u2013884","journal-title":"J Oral Maxillofac Surg"},{"key":"5020_CR18","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.adaj.2024.12.008","volume":"156","author":"F Ferreira Gonz\u00e1lez","year":"2025","unstructured":"Ferreira Gonz\u00e1lez F, Caponio VCA, L\u00f3pez-Pintor RM et al (2025) Effectiveness of low-level diode laser in the management of complications after third-molar surgical extraction: Systematic review and meta-analysis. J Am Dent Assoc 156:211\u2013224e11","journal-title":"J Am Dent Assoc"},{"key":"5020_CR19","doi-asserted-by":"publisher","first-page":"102080","DOI":"10.1016\/j.jebdp.2024.102080","volume":"25","author":"GCV Camolesi","year":"2025","unstructured":"Camolesi GCV, El Kattan AS, Lopez-Lopez J et al (2025) Pain, oedema and trismus responses following photobiomodulation therapy immediately after lower third molar extraction: Results of a randomized, Doble-blind and split mouth clinical trial. J Evid Based Dent Pract 25:102080","journal-title":"J Evid Based Dent Pract"},{"key":"5020_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12903-022-02461-2","volume":"22","author":"E Momeni","year":"2022","unstructured":"Momeni E, Kazemi F, Sanaei-rad P (2022) Extraoral low-level laser therapy can decrease pain but not edema and trismus after surgical extraction of impacted mandibular third molars: a randomized, placebo-controlled clinical trial. BMC Oral Health 22:1\u20138","journal-title":"BMC Oral Health"},{"key":"5020_CR21","doi-asserted-by":"publisher","first-page":"101983","DOI":"10.1016\/j.jebdp.2024.101983","volume":"24","author":"GCV Camolesi","year":"2024","unstructured":"Camolesi GCV, Silva FFVE, Aulestia-Viera PV et al (2024) Is the photobiomodulation therapy effective in controlling post-surgical side effects after the extraction of mandibular third molars? A systematic review and meta-analysis. J Evid Based Dent Pract 24:101983","journal-title":"J Evid Based Dent Pract"},{"key":"5020_CR22","doi-asserted-by":"publisher","first-page":"S52","DOI":"10.4103\/njms.NJMS_52_20","volume":"13","author":"SD Thorat","year":"2022","unstructured":"Thorat SD, Nilesh K (2022) Efficacy of low-level laser therapy in the management of postoperative surgical sequelae after surgical removal of impacted mandibular third molars. Natl J Maxillofac Surg 13:S52\u2013S56","journal-title":"Natl J Maxillofac Surg"},{"key":"5020_CR23","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1186\/s12903-025-05589-z","volume":"25","author":"S Kar\u015f\u0131c\u0131","year":"2025","unstructured":"Kar\u015f\u0131c\u0131 S, Balaban E (2025) The effect of preoperative low-level laser therapy on pain, swelling, and trismus associated with mandibular third molar extraction. BMC Oral Health 25:306","journal-title":"BMC Oral Health"},{"key":"5020_CR24","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1007\/s10103-024-03973-9","volume":"39","author":"E Baydan","year":"2024","unstructured":"Baydan E, Soylu E (2024) Investigation of the efficacy of two different laser types in the treatment of lower lip paresthesia after sagittal split ramus osteotomy. Lasers Med Sci 39:23","journal-title":"Lasers Med Sci"},{"key":"5020_CR25","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1186\/s12903-025-06331-5","volume":"25","author":"G Karaday\u0131","year":"2025","unstructured":"Karaday\u0131 G, Akbulut N, Deresoy FA, Altan A (2025) Comparison of the effectiveness of the new generation dual wavelength laser with the conventional laser type in treating rabbit model temporomandibular joint osteoarthritis. BMC Oral Health 25:980","journal-title":"BMC Oral Health"},{"key":"5020_CR26","doi-asserted-by":"publisher","first-page":"31","DOI":"10.54589\/aol.35\/1\/31","volume":"35","author":"GM Ferreira","year":"2022","unstructured":"Ferreira GM, Prado LF, Santos KV et al (2022) Efficacy of two low-level laser therapy protocols following lower third molar surgery - a randomized, double-blind, controlled clinical trial. Acta Odontol Latinoam 35:31\u201338","journal-title":"Acta Odontol Latinoam"},{"key":"5020_CR27","doi-asserted-by":"publisher","first-page":"98","DOI":"10.4103\/njms.njms_67_23","volume":"16","author":"RS Tiwari","year":"2025","unstructured":"Tiwari RS, Deshpande N, Mundada B et al (2025) Effects of low-level laser therapy and intramasseteric triamcinolone on postoperative sequelae following mandibular third molar surgery: A comparative study. Natl J Maxillofac Surg 16:98\u2013103","journal-title":"Natl J Maxillofac Surg"}],"container-title":["Lasers in Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-026-05020-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10103-026-05020-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-026-05020-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T09:16:27Z","timestamp":1789550187000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10103-026-05020-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,16]]},"references-count":27,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["5020"],"URL":"https:\/\/doi.org\/10.1007\/s10103-026-05020-1","relation":{},"ISSN":["1435-604X"],"issn-type":[{"value":"1435-604X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,16]]},"assertion":[{"value":"1 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study was conducted in accordance with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee for Non-Drug and Non-Medical Device Research of [Anonymized University](Decision No: 2025\/535, Date: January 30, 2025).","order":1,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent was obtained from all individual participants included in the study.","order":2,"name":"Ethics","label":"Informed Consent","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"NCT07522918.","order":4,"name":"Ethics","label":"Clinical Trial Number","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"236"}}