{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:52:28Z","timestamp":1792068748792,"version":"4.4.0"},"reference-count":121,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lasers Med Sci"],"DOI":"10.1007\/s10103-026-05064-3","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:12:42Z","timestamp":1792041162000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Umbrella review of low-level light therapy: evidence across clinical conditions"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5717-5117","authenticated-orcid":false,"given":"Eunhye","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7273-9600","authenticated-orcid":false,"given":"Lin","family":"Ang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0313-6694","authenticated-orcid":false,"given":"Mi Hong","family":"Yim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunmi","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihye","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"issue":"6","key":"5064_CR1","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1093\/asj\/sjab025","volume":"41","author":"GE Glass","year":"2021","unstructured":"Glass GE, Photobiomodulation (2021) The clinical applications of low-level light therapy. Aesthetic Surg J 41(6):723\u2013738","journal-title":"Aesthetic Surg J"},{"key":"5064_CR2","doi-asserted-by":"crossref","unstructured":"Minotto R, Damiani L, Tip Chapter (2020) Low-Level Light Therapy and High-Energy Lasers in Trichology. Minimally Invasive Aesthetic Procedures: A Guide for Dermatologists and Plastic Surgeons pp. 777-9","DOI":"10.1007\/978-3-319-78265-2_109"},{"issue":"3","key":"5064_CR3","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1007\/s12264-023-01089-8","volume":"40","author":"X Huang","year":"2024","unstructured":"Huang X, Tao Q, Ren C (2024) A Comprehensive Overview of the Neural Mechanisms of Light Therapy. Neurosci Bull 40(3):350\u2013362","journal-title":"Neurosci Bull"},{"issue":"1","key":"5064_CR4","first-page":"30","volume":"12","author":"G Lodi","year":"2025","unstructured":"Lodi G, Cassalia F, Sannino M, Cannarozzo G, Baroni A, Amato S et al (2025) Blue Light Therapy Dermatological Practice: Rev Cosmetics 12(1):30","journal-title":"Blue Light Therapy Dermatological Practice: Rev Cosmetics"},{"issue":"4","key":"5064_CR5","first-page":"1","volume":"32","author":"HB Kang","year":"2026","unstructured":"Kang HB, Son WC, Lee HR, Koh EK, Park GY, Park YS (2026) Biological Effects of Light-Emitting Diode (LED)-Based Low-Level Light on Natural Killer Cells. IEEE J Sel Top Quantum Electron 32(4):1\u201310","journal-title":"IEEE J Sel Top Quantum Electron"},{"key":"5064_CR6","unstructured":"Prabhu V, Rathnakar B, Mahato KK (2020) Photobiomodulation of tissue repair and regeneration. Laser Therapies: Types, Uses and Safety pp. 119\u2009\u2013\u200946"},{"issue":"2","key":"5064_CR7","doi-asserted-by":"crossref","first-page":"94","DOI":"10.4103\/ijds.ijds_81_22","volume":"15","author":"TA Khot","year":"2023","unstructured":"Khot TA, Lele P, Dodwad V, Bhosale NS, Mariam S, Upadhyay S (2023) Photobiomodulation: Molecular and Subcellular Mechanisms and Applications in Periodontal Therapy. Indian J Dent Sci 15(2):94\u201398","journal-title":"Indian J Dent Sci"},{"issue":"2","key":"5064_CR8","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.jaad.2025.04.031","volume":"93","author":"J Maghfour","year":"2025","unstructured":"Maghfour J, Mineroff J, Ozog DM, Jagdeo J, Lim HW, Kohli I et al (2025) Evidence-based consensus on the clinical application of photobiomodulation. J Am Acad Dermatol 93(2):429\u2013443","journal-title":"J Am Acad Dermatol"},{"issue":"1","key":"5064_CR9","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1007\/s10103-025-04393-z","volume":"40","author":"R Tamimi","year":"2025","unstructured":"Tamimi R, Benisi SZ, Boroujeni ME, Torkamani MJ (2025) Review on the molecular mechanisms of low-level laser therapy: gene expression and signaling pathways. Lasers Med Sci 40(1):160","journal-title":"Lasers Med Sci"},{"key":"5064_CR10","first-page":"201","volume-title":"Light Emitting Diodes and Low Level Laser Light Therapy. Practical Introduction to Laser Dermatology","author":"C Zheng","year":"2020","unstructured":"Zheng C, Rajabi-Estarabadi A, Hirsch MM, Nouri K (2020) Light Emitting Diodes and Low Level Laser Light Therapy. Practical Introduction to Laser Dermatology. Springer, Cham, pp 201\u2013201"},{"issue":"1","key":"5064_CR11","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1007\/s10103-025-04417-8","volume":"40","author":"OF Al Balah","year":"2025","unstructured":"Al Balah OF, Rafie M, Osama AR (2025) Immunomodulatory effects of photobiomodulation: a comprehensive review. Lasers Med Sci 40(1):187","journal-title":"Lasers Med Sci"},{"issue":"12","key":"5064_CR12","first-page":"1457","volume":"23","author":"Q Cheng","year":"2023","unstructured":"Cheng Q, Yang Q, Tian C, Lu Y, Li Y, Ge L (2023) The formulation methods and steps of umbrella review. Chin J Evidence-Based Med 23(12):1457\u20131464","journal-title":"Chin J Evidence-Based Med"},{"key":"5064_CR13","doi-asserted-by":"crossref","first-page":"e070849","DOI":"10.1136\/bmj-2022-070849","volume":"378","author":"M Gates","year":"2022","unstructured":"Gates M, Gates A, Pieper D, Fernandes RM, Tricco AC, Moher D et al (2022) Reporting guideline for overviews of reviews of healthcare interventions: development of the PRIOR statement. BMJ 378:e070849","journal-title":"BMJ"},{"key":"5064_CR14","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71","journal-title":"BMJ"},{"key":"5064_CR15","doi-asserted-by":"crossref","first-page":"j4008","DOI":"10.1136\/bmj.j4008","volume":"358","author":"BJ Shea","year":"2017","unstructured":"Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C, Moran J et al (2017) AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ 358:j4008","journal-title":"BMJ"},{"key":"5064_CR16","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.34172\/jlms.2023.17","volume":"14","author":"F Abesi","year":"2023","unstructured":"Abesi F, Derikvand N (2023) Efficacy of Low-Level Laser Therapy in Wound Healing and Pain Reduction After Gingivectomy: A Systematic Review and Meta-analysis. J Lasers Med Sci 14:e17","journal-title":"J Lasers Med Sci"},{"key":"5064_CR17","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.2147\/JMDH.S281495","volume":"13","author":"MK Ahmed","year":"2020","unstructured":"Ahmed MK, Jafer M, Nayeem M, Hussain Moafa I, Quadri MFA, Gopalaiah H et al (2020) Low-Level Laser Therapy and Topical Medications for Treating Aphthous Ulcers: A Systematic Review. J Multidiscip Healthc 13:1595\u20131605","journal-title":"J Multidiscip Healthc"},{"issue":"1","key":"5064_CR18","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/jop.12619","volume":"47","author":"Z Akram","year":"2018","unstructured":"Akram Z, Abduljabbar T, Vohra F, Javed F (2018) Efficacy of low-level laser therapy compared to steroid therapy in the treatment of oral lichen planus: A systematic review. J Oral Pathol Med 47(1):11\u201317","journal-title":"J Oral Pathol Med"},{"issue":"4","key":"5064_CR19","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/jerd.12377","volume":"30","author":"Z Akram","year":"2018","unstructured":"Akram Z, Vohra F, Javed F (2018) Low-level laser therapy as an adjunct to connective tissue graft procedure in the treatment of gingival recession defects: A systematic review and meta-analysis. J Esthet Restor Dent 30(4):299\u2013306","journal-title":"J Esthet Restor Dent"},{"issue":"7","key":"5064_CR20","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1007\/s10103-018-2542-5","volume":"33","author":"SA Al-Maweri","year":"2018","unstructured":"Al-Maweri SA, Kalakonda B, AlAizari NA, Al-Soneidar WA, Ashraf S, Abdulrab S et al (2018) Efficacy of low-level laser therapy in management of recurrent herpes labialis: a systematic review. Lasers Med Sci 33(7):1423\u20131430","journal-title":"Lasers Med Sci"},{"issue":"1","key":"5064_CR21","doi-asserted-by":"crossref","first-page":"73","DOI":"10.17219\/dmp\/112446","volume":"57","author":"WMM Bakdach","year":"2020","unstructured":"Bakdach WMM, Hadad R (2020) Effectiveness of low-level laser therapy in accelerating the orthodontic tooth movement: A systematic review and meta-analysis. Dent Med Probl 57(1):73\u201394","journal-title":"Dent Med Probl"},{"issue":"3","key":"5064_CR22","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.ijom.2021.06.006","volume":"51","author":"LM Barbosa","year":"2022","unstructured":"Barbosa LM, de Luna Gomes JM, Laureano Filho JR, do Egito Vasconcelos BC, Dantas Moraes SL, Pellizzer EP (2022) Does the use of low-level light therapy postoperatively reduce pain, oedema, and neurosensory disorders following orthognathic surgery? A systematic review. Int J Oral Maxillofac Surg 51(3):355\u2013365","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"9","key":"5064_CR23","doi-asserted-by":"publisher","first-page":"3393","DOI":"10.1007\/s10103-022-03653-6","volume":"37","author":"AWP Barros","year":"2022","unstructured":"Barros AWP, Sales P, Silva PGB, Gomes ACA, Carvalho AAT, Le\u00e3o JC (2022) Is low-level laser therapy effective in the treatment of herpes labialis? Systematic review and meta-analysis. Lasers Med Sci 37(9):3393\u20133402","journal-title":"Lasers Med Sci"},{"issue":"2","key":"5064_CR24","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1007\/s10103-021-03425-8","volume":"37","author":"CL Bitencourt Reis","year":"2022","unstructured":"Bitencourt Reis CL, de Souza Furtado TC, Mendes WD, Matsumoto MAN, Alves SYF, Stuani MBS et al (2022) Photobiomodulation impacts the levels of inflammatory mediators during orthodontic tooth movement? A systematic review with meta-analysis. Lasers Med Sci 37(2):771\u2013787","journal-title":"Lasers Med Sci"},{"issue":"6","key":"5064_CR25","first-page":"780","volume":"22","author":"MA Bittencourt","year":"2017","unstructured":"Bittencourt MA, Paranhos LR, Martins-Filho PR (2017) Low-level laser therapy for treatment of neurosensory disorders after orthognathic surgery: A systematic review of randomized clinical trials. Med Oral Patol Oral Cir Bucal 22(6):780\u2013787","journal-title":"Med Oral Patol Oral Cir Bucal"},{"issue":"1","key":"5064_CR26","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/aej.70052","volume":"52","author":"G Bonacina","year":"2026","unstructured":"Bonacina G, Hartmann RC, Gomes MS, B\u00f6ttcher DE (2026) Analgesic Efficacy of Low-Level Laser Therapy for Postoperative Endodontic Pain: A Systematic Review and Meta-Analysis. AUSTRALIAN ENDODONTIC J 52(1):310\u2013322","journal-title":"AUSTRALIAN ENDODONTIC J"},{"issue":"7","key":"5064_CR27","doi-asserted-by":"publisher","first-page":"2791","DOI":"10.1007\/s10103-022-03578-0","volume":"37","author":"AMP Carneiro","year":"2022","unstructured":"Carneiro AMP, Barros APO, de Oliveira RP, de Paula BLF, Silva AM, de Melo Alencar C et al (2022) The effect of photobiomodulation using low-level laser therapy on tooth sensitivity after dental bleaching: a systematic review. Lasers Med Sci 37(7):2791\u20132804","journal-title":"Lasers Med Sci"},{"issue":"7","key":"5064_CR28","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1007\/s10103-019-02793-6","volume":"34","author":"Y Chen","year":"2019","unstructured":"Chen Y, Chen XL, Zou XL, Chen SZ, Zou J, Wang Y (2019) Efficacy of low-level laser therapy in pain management after root canal treatment or retreatment: a systematic review. Lasers Med Sci 34(7):1305\u20131316","journal-title":"Lasers Med Sci"},{"issue":"1","key":"5064_CR29","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1007\/s10103-023-03720-6","volume":"38","author":"PC da Silva Mira","year":"2023","unstructured":"da Silva Mira PC, Vilela LD, Corona SAM, Borsatto MC (2023) Effect of low-level laser stimulation of acupuncture points in pediatric dentistry: a systematic review. Lasers Med Sci 38(1):52","journal-title":"Lasers Med Sci"},{"issue":"1","key":"5064_CR30","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/s40510-021-00350-y","volume":"22","author":"AC de Figueiredo Costa","year":"2021","unstructured":"de Figueiredo Costa AC, Maia TAC, de Barros Silva PG, Abreu LG, Gondim DV, Santos PCF (2021) Effects of low-level laser therapy on the orthodontic mini-implants stability: a systematic review and meta-analysis. Prog Orthod 22(1):6","journal-title":"Prog Orthod"},{"issue":"1","key":"5064_CR31","doi-asserted-by":"crossref","first-page":"13","DOI":"10.11607\/ofph.2310","volume":"34","author":"M de Pedro","year":"2020","unstructured":"de Pedro M, L\u00f3pez-Pintor RM, de la Hoz-Aizpurua JL, Casa\u00f1as E, Hern\u00e1ndez G (2020) Efficacy of Low-Level Laser Therapy for the Therapeutic Management of Neuropathic Orofacial Pain: A Systematic Review. J Oral Facial Pain Headache 34(1):13\u201330","journal-title":"J Oral Facial Pain Headache"},{"key":"5064_CR32","doi-asserted-by":"crossref","first-page":"8560652","DOI":"10.1155\/2017\/8560652","volume":"2017","author":"NF Deana","year":"2017","unstructured":"Deana NF, Zaror C, Sandoval P, Alves N (2017) Effectiveness of Low-Level Laser Therapy in Reducing Orthodontic Pain: A Systematic Review and Meta-Analysis. Pain Res Manag 2017:8560652","journal-title":"Pain Res Manag"},{"key":"5064_CR33","doi-asserted-by":"crossref","first-page":"104516","DOI":"10.1016\/j.pdpdt.2025.104516","volume":"52","author":"L D\u00edaz","year":"2025","unstructured":"D\u00edaz L, Basualdo J, Gil AC, Von Marttens A, Fern\u00e1ndez E (2025) Effectiveness of low-level laser therapy in patients with maxillofacial neuropathies. A systematic review of randomized controlled trials. Photodiagnosis Photodyn Ther 52:104516","journal-title":"Photodiagnosis Photodyn Ther"},{"issue":"9","key":"5064_CR34","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.5005\/jp-journals-10005-2947","volume":"17","author":"AR Doiphode","year":"2024","unstructured":"Doiphode AR, Kalaskar R, Kalaskar A, Honaje NV, Gala UP (2024) Clinical and Radiographic Efficacy of Low-level Laser Therapy and Formocresol as Pulpotomy Agents in Primary Molars: A Systematic Review and Meta-analysis. Int J Clin Pediatr Dent 17(9):1075\u20131085","journal-title":"Int J Clin Pediatr Dent"},{"issue":"2","key":"5064_CR35","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.joms.2020.09.018","volume":"79","author":"F Domah","year":"2021","unstructured":"Domah F, Shah R, Nurmatov UB, Tagiyeva N (2021) The Use of Low-Level Laser Therapy to Reduce Postoperative Morbidity After Third Molar Surgery: A Systematic Review and Meta-Analysis. J Oral Maxillofac Surg 79(2):313.","journal-title":"J Oral Maxillofac Surg"},{"issue":"5","key":"5064_CR36","doi-asserted-by":"publisher","first-page":"2363","DOI":"10.1007\/s10103-021-03470-3","volume":"37","author":"D Domingos de Barros","year":"2022","unstructured":"Domingos de Barros D, Dos Santos Barros Cat\u00e3o JS, Ferreira ACD, Sim\u00f5es TMS, Almeida RAC, de Vasconcelos Cat\u00e3o MHC (2022) Low-level laser therapy is effective in controlling postoperative pain in lower third molar extractions: a systematic review and meta-analysis. Lasers Med Sci 37(5):2363\u20132377","journal-title":"Lasers Med Sci"},{"issue":"11","key":"5064_CR37","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.jcms.2021.06.006","volume":"49","author":"FJ Duarte de Oliveira","year":"2021","unstructured":"Duarte de Oliveira FJ, Brasil G, Ara\u00fajo Soares GP, Fernandes Paiva DF, de Assis de Souza J\u00fanior F (2021) Use of low-level laser therapy to reduce postoperative pain, edema, and trismus following third molar surgery: A systematic review and meta-analysis. J Craniomaxillofac Surg 49(11):1088\u20131096","journal-title":"J Craniomaxillofac Surg"},{"key":"5064_CR38","doi-asserted-by":"crossref","first-page":"e29","DOI":"10.34172\/jlms.2021.29","volume":"12","author":"A Farzan","year":"2021","unstructured":"Farzan A, Khaleghi K (2021) The Effectiveness of Low-Level Laser Therapy in Pain Induced by Orthodontic Separator Placement: A Systematic Review. J Lasers Med Sci 12:e29","journal-title":"J Lasers Med Sci"},{"key":"5064_CR39","doi-asserted-by":"crossref","first-page":"e13","DOI":"10.34172\/jlms.2022.13","volume":"13","author":"A Farzan","year":"2022","unstructured":"Farzan A, Khaleghi K, Pirayesh Z (2022) Effect of Low-Level Laser Therapy on Bone Formation in Rapid Palatal Expansion: A Systematic Review. J Lasers Med Sci 13:e13","journal-title":"J Lasers Med Sci"},{"issue":"3","key":"5064_CR40","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.adaj.2024.12.008","volume":"156","author":"F Ferreira Gonz\u00e1lez","year":"2025","unstructured":"Ferreira Gonz\u00e1lez F, Caponio VCA, L\u00f3pez-Pintor RM, Kemcha N, Torres J, Leco Berrocal I (2025) Effectiveness of low-level diode laser in the management of complications after third-molar surgical extraction: Systematic review and meta-analysis. J Am Dent Assoc 156(3):211\u201324e11","journal-title":"J Am Dent Assoc"},{"issue":"1","key":"5064_CR41","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s40902-020-00285-0","volume":"42","author":"P Firoozi","year":"2020","unstructured":"Firoozi P, Keyhan SO, Kim SG, Fallahi HR (2020) Effectiveness of low-level laser therapy on recovery from neurosensory disturbance after sagittal split ramus osteotomy: a systematic review and meta-analysis. Maxillofac Plast Reconstr Surg 42(1):41","journal-title":"Maxillofac Plast Reconstr Surg"},{"issue":"30","key":"5064_CR42","doi-asserted-by":"crossref","first-page":"e43559","DOI":"10.1097\/MD.0000000000043559","volume":"104","author":"S Gao","year":"2025","unstructured":"Gao S, Wu P, Cheng Y (2025) Comparative efficacy of ibuprofen and low-level laser therapy on pain intensity after elastomeric separator placement: A systematic review and network meta-analysis. Medicine 104(30):e43559","journal-title":"Medicine"},{"issue":"5","key":"5064_CR43","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1007\/s10103-014-1538-z","volume":"30","author":"MK Ge","year":"2015","unstructured":"Ge MK, He WL, Chen J, Wen C, Yin X, Hu ZA et al (2015) Efficacy of low-level laser therapy for accelerating tooth movement during orthodontic treatment: a systematic review and meta-analysis. Lasers Med Sci 30(5):1609\u20131618","journal-title":"Lasers Med Sci"},{"issue":"1","key":"5064_CR44","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s41547-025-00280-6","volume":"9","author":"F Ghaderi","year":"2025","unstructured":"Ghaderi F, Ardakani MSZ, Afshari M (2025) Evaluating pain relief of dental procedures with low-level laser therapy in children: a systematic review. Lasers Dent Sci 9(1):6","journal-title":"Lasers Dent Sci"},{"key":"5064_CR45","doi-asserted-by":"crossref","first-page":"104594","DOI":"10.1016\/j.pdpdt.2025.104594","volume":"53","author":"AC Gil","year":"2025","unstructured":"Gil AC, D\u00edaz L, Von Martens A, Sotomayor C, Basualdo J, Beltr\u00e1n V et al (2025) The efficacy of low-level laser therapy in oral surgery: A systematic review of randomized controlled trials. Photodiagn Photodyn Ther 53:104594","journal-title":"Photodiagn Photodyn Ther"},{"issue":"1","key":"5064_CR46","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1007\/s10103-023-03870-7","volume":"38","author":"M Grajales","year":"2023","unstructured":"Grajales M, R\u00edos-Osorio N, Jimenez-Pe\u00f1a O, Mendez-Sanchez J, Sanchez-Fajardo K, Garc\u00eda-Perdomo HA (2023) Effectiveness of photobiomodulation with low-level lasers on the acceleration of orthodontic tooth movement: a systematic review and meta-analysis of split-mouth randomised clinical trials. Lasers Med Sci 38(1):200","journal-title":"Lasers Med Sci"},{"issue":"6","key":"5064_CR47","doi-asserted-by":"publisher","first-page":"1581","DOI":"10.1007\/s10103-012-1196-y","volume":"28","author":"WL He","year":"2013","unstructured":"He WL, Li CJ, Liu ZP, Sun JF, Hu ZA, Yin X et al (2013) Efficacy of low-level laser therapy in the management of orthodontic pain: a systematic review and meta-analysis. Lasers Med Sci 28(6):1581\u20131589","journal-title":"Lasers Med Sci"},{"issue":"6","key":"5064_CR48","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1007\/s10103-014-1634-0","volume":"30","author":"WL He","year":"2015","unstructured":"He WL, Yu FY, Li CJ, Pan J, Zhuang R, Duan PJ (2015) A systematic review and meta-analysis on the efficacy of low-level laser therapy in the management of complication after mandibular third molar surgery. Lasers Med Sci 30(6):1779\u20131788","journal-title":"Lasers Med Sci"},{"key":"5064_CR49","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.pdpdt.2018.07.001","volume":"23","author":"H Jajarm","year":"2018","unstructured":"Jajarm H, Asadi R, Bardideh E, Shafaee H, Khazaei Y, Emadzadeh M (2018) The effects of photodynamic and low-level laser therapy for treatment of oral lichen planus-A systematic review and meta-analysis. Photodiagnosis Photodyn Ther 23:254\u2013260","journal-title":"Photodiagnosis Photodyn Ther"},{"key":"5064_CR50","doi-asserted-by":"crossref","first-page":"14","DOI":"10.4103\/jos.jos_182_21","volume":"12","author":"PR Jnaneshwar","year":"2023","unstructured":"Jnaneshwar PR, Venkatesan K, Prince T, Pethuraj V, Rajaram K, Bhat S (2023) Assessment of the effect of frequency of low-level laser therapy exposure at different intervals on orthodontic tooth movement - A systematic review and meta-analysis. J Orthod Sci 12:14","journal-title":"J Orthod Sci"},{"issue":"6","key":"5064_CR51","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1007\/s10103-014-1661-x","volume":"30","author":"FJ Li","year":"2015","unstructured":"Li FJ, Zhang JY, Zeng XT, Guo Y (2015) Low-level laser therapy for orthodontic pain: a systematic review. Lasers Med Sci 30(6):1789\u20131803","journal-title":"Lasers Med Sci"},{"issue":"1","key":"5064_CR52","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1186\/s12903-023-03441-w","volume":"23","author":"C Lu","year":"2023","unstructured":"Lu C, Yang C, Li X, Du G, Zhou X, Luo W et al (2023) Effects of low-level laser therapy on burning pain and quality of life in patients with burning mouth syndrome: a systematic review and meta-analysis. BMC Oral Health 23(1):734","journal-title":"BMC Oral Health"},{"issue":"2","key":"5064_CR53","doi-asserted-by":"crossref","first-page":"102126","DOI":"10.1016\/j.jebdp.2025.102126","volume":"25","author":"C Lu","year":"2025","unstructured":"Lu C, Mo L, Li XIN, Du G, Chen Z, Wu FAN et al (2025) Effects of low-level light therapy on pain and related lesions in patients with oral lichen planus: a systematic review and meta-analysis. J Evidence-Based Dent Pract 25(2):102126","journal-title":"J Evidence-Based Dent Pract"},{"issue":"3","key":"5064_CR54","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1007\/s10103-021-03467-y","volume":"37","author":"D Meneses-Santos","year":"2022","unstructured":"Meneses-Santos D, Costa M, Inoc\u00eancio GSG, Almeida AC, Vieira WA, Lima IFP et al (2022) Effects of low-level laser therapy on reducing pain, edema, and trismus after orthognathic surgery: a systematic review. Lasers Med Sci 37(3):1471\u20131485","journal-title":"Lasers Med Sci"},{"issue":"1","key":"5064_CR55","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/ejo\/cjab016","volume":"44","author":"D Michelogiannakis","year":"2022","unstructured":"Michelogiannakis D, Jabr L, Barmak AB, Rossouw PE, Kotsailidi EA, Javed F (2022) Influence of low-level-laser therapy on the stability of orthodontic mini-screw implants. A systematic review and meta-analysis. Eur J Orthod 44(1):11\u201321","journal-title":"Eur J Orthod"},{"issue":"5","key":"5064_CR56","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1007\/s10103-019-02718-3","volume":"34","author":"A Mirzaei","year":"2019","unstructured":"Mirzaei A, Saberi-Demneh A, Gutknecht N, Ramezani G (2019) The effect of low-level laser radiation on improving inferior alveolar nerve damage after sagittal split osteotomy: a systematic review. Lasers Med Sci 34(5):865\u2013872","journal-title":"Lasers Med Sci"},{"issue":"2","key":"5064_CR57","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1007\/s10103-015-1860-0","volume":"31","author":"JC Prados-Frutos","year":"2016","unstructured":"Prados-Frutos JC, Rodr\u00edguez-Molinero J, Prados-Privado M, Torres JH, Rojo R (2016) Lack of clinical evidence on low-level laser therapy (LLLT) on dental titanium implant: a systematic review. Lasers Med Sci 31(2):383\u2013392","journal-title":"Lasers Med Sci"},{"issue":"1","key":"5064_CR58","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1186\/s13643-024-02595-0","volume":"13","author":"D Radithia","year":"2024","unstructured":"Radithia D, Mahdani FY, Bakti RK, Parmadiati AE, Subarnbhesaj A, Pramitha SR et al (2024) Effectiveness of low-level laser therapy in reducing pain score and healing time of recurrent aphthous stomatitis: a systematic review and meta-analysis. Syst Rev 13(1):192","journal-title":"Syst Rev"},{"key":"5064_CR59","doi-asserted-by":"crossref","first-page":"102638","DOI":"10.1016\/j.ctim.2020.102638","volume":"57","author":"MY Reis Guerreiro","year":"2021","unstructured":"Reis Guerreiro MY, Monteiro LPB, de Castro RF, Magno MB, Maia LC, da Silva Brand\u00e3o JM (2021) Effect of low-level laser therapy on postoperative endodontic pain: An updated systematic review. Complement Ther Med 57:102638","journal-title":"Complement Ther Med"},{"issue":"7","key":"5064_CR60","doi-asserted-by":"publisher","first-page":"1881","DOI":"10.1007\/s10103-015-1743-4","volume":"30","author":"C Ren","year":"2015","unstructured":"Ren C, McGrath C, Yang Y (2015) The effectiveness of low-level diode laser therapy on orthodontic pain management: a systematic review and meta-analysis. Lasers Med Sci 30(7):1881\u20131893","journal-title":"Lasers Med Sci"},{"key":"5064_CR61","doi-asserted-by":"crossref","first-page":"103759","DOI":"10.1016\/j.pdpdt.2023.103759","volume":"44","author":"H Shafaee","year":"2023","unstructured":"Shafaee H, Asgari R, Bardideh E, Rangrazi A, Sedigh S, Kerayechian N (2023) The effects of low-level laser therapy and photodynamic therapy on oral health of fixed orthodontics patients. A systematic review and meta-analysis. Photodiagnosis Photodyn Ther 44:103759","journal-title":"Photodiagnosis Photodyn Ther"},{"issue":"12","key":"5064_CR62","doi-asserted-by":"crossref","first-page":"6571","DOI":"10.1007\/s00784-021-04183-1","volume":"25","author":"Z Shan","year":"2021","unstructured":"Shan Z, Ji J, McGrath C, Gu M, Yang Y (2021) Effects of low-level light therapy on dentin hypersensitivity: a systematic review and meta-analysis. Clin Oral Investig 25(12):6571\u20136595","journal-title":"Clin Oral Investig"},{"issue":"2","key":"5064_CR63","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1089\/pho.2017.4278","volume":"36","author":"FG Skondra","year":"2018","unstructured":"Skondra FG, Koletsi D, Eliades T, Farmakis ETR (2018) The Effect of Low-Level Laser Therapy on Bone Healing After Rapid Maxillary Expansion: A Systematic Review. Photomed Laser Surg 36(2):61\u201371","journal-title":"Photomed Laser Surg"},{"issue":"20","key":"5064_CR64","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1080\/09638288.2022.2127933","volume":"45","author":"AI Sobral de Oliveira-Souza","year":"2023","unstructured":"Sobral de Oliveira-Souza AI, Mohamad N, de Castro Carletti EM, M\u00fcggenborg F, Dennett L, de Oliveira DA et al (2023) What are the best parameters of low-level laser therapy to reduce pain intensity and improve mandibular function in orofacial pain? A systematic review and meta-analysis. Disabil Rehabil 45(20):3219\u20133237","journal-title":"Disabil Rehabil"},{"issue":"2","key":"5064_CR65","doi-asserted-by":"crossref","first-page":"281","DOI":"10.17219\/dmp\/143242","volume":"59","author":"A Vande","year":"2022","unstructured":"Vande A, Sanyal PK, Nilesh K (2022) Effectiveness of the photobiomodulation therapy using low-level laser around dental implants: A systematic review and meta-analysis. Dent Med Probl 59(2):281\u2013289","journal-title":"Dent Med Probl"},{"issue":"1","key":"5064_CR66","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/s10103-020-03072-5","volume":"36","author":"H Zhao","year":"2021","unstructured":"Zhao H, Hu J, Zhao L (2021) The effect of low-level laser therapy as an adjunct to periodontal surgery in the management of postoperative pain and wound healing: a systematic review and meta-analysis. Lasers Med Sci 36(1):175\u2013187","journal-title":"Lasers Med Sci"},{"issue":"1","key":"5064_CR67","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1007\/s10103-023-03835-w","volume":"38","author":"DH Zheng","year":"2023","unstructured":"Zheng DH, Du YQ, Zhang QQ, Hou FC, Niu SQ, Zang YJ et al (2023) Effect of low-level laser therapy on orthodontic dental alignment: a systematic review and meta-analysis. Lasers Med Sci 38(1):184","journal-title":"Lasers Med Sci"},{"issue":"1","key":"5064_CR68","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1186\/s40001-023-01010-z","volume":"28","author":"DH Zheng","year":"2023","unstructured":"Zheng DH, Hou FC, Zang YJ, Li B (2023) Effects of low-level laser therapy on orthodontic miniscrew stability: a systematic review. Eur J Med Res 28(1):50","journal-title":"Eur J Med Res"},{"issue":"2","key":"5064_CR69","doi-asserted-by":"crossref","first-page":"148","DOI":"10.25122\/jml-2020-0169","volume":"14","author":"SA Ahmad","year":"2021","unstructured":"Ahmad SA, Hasan S, Saeed S, Khan A, Khan M (2021) Low-level laser therapy in temporomandibular joint disorders: a systematic review. J Med Life 14(2):148\u2013164","journal-title":"J Med Life"},{"issue":"6","key":"5064_CR70","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1007\/s10103-017-2234-6","volume":"32","author":"AH Bekhet","year":"2017","unstructured":"Bekhet AH, Ragab B, Abushouk AI, Elgebaly A, Ali OI (2017) Efficacy of low-level laser therapy in carpal tunnel syndrome management: a systematic review and meta-analysis. Lasers Med Sci 32(6):1439\u20131448","journal-title":"Lasers Med Sci"},{"issue":"6","key":"5064_CR71","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1177\/0269215520912820","volume":"34","author":"AL Cabrera Martimbianco","year":"2020","unstructured":"Cabrera Martimbianco AL, Ferreira RES, Latorraca COC, Bussadori SK, Pacheco RL, Riera R (2020) Photobiomodulation with low-level laser therapy for treating Achilles tendinopathy: a systematic review and meta-analysis. Clin Rehabil 34(6):713\u2013722","journal-title":"Clin Rehabil"},{"key":"5064_CR72","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.physio.2019.06.005","volume":"106","author":"WKW Cheung","year":"2020","unstructured":"Cheung WKW, Wu IXY, Sit RWS, Ho RST, Wong CHL, Wong SYS et al (2020) Low-level laser therapy for carpal tunnel syndrome: systematic review and network meta-analysis. Physiotherapy 106:24\u201335","journal-title":"Physiotherapy"},{"issue":"3","key":"5064_CR73","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5114\/pq.2023.117021","volume":"33","author":"HA de la Barra Ortiz","year":"2025","unstructured":"de la Barra Ortiz HA, De La Maza TC, Gascon-Madrid MJ, Hormazabal-Cerda G, Meza-Arellano A, Chamorro-Lange C (2025) The effects of low-level laser therapy in De Quervain tenosynovitis: evidence from a systematic review and meta-analysis. Physiotherapy Q 33(3):1\u201312","journal-title":"Physiotherapy Q"},{"issue":"1","key":"5064_CR74","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1007\/s10103-026-04812-9","volume":"41","author":"HA de la Barra Ortiz","year":"2026","unstructured":"de la Barra Ortiz HA, Parizotto NA, Liebano RE (2026) Comparison of the effectiveness of high-intensity laser therapy versus low-level laser therapy in musculoskeletal disorders: a systematic review and network meta-analysis. Lasers Med Sci 41(1):30","journal-title":"Lasers Med Sci"},{"key":"5064_CR75","doi-asserted-by":"crossref","first-page":"104558","DOI":"10.1016\/j.pdpdt.2025.104558","volume":"53","author":"L D\u00edaz","year":"2025","unstructured":"D\u00edaz L, Restelli L, Valencia E, Atalay DI, Abarca JM, Gil AC et al (2025) Effectiveness of low-level laser therapy on temporomandibular disorders. A systematic review of randomized clinical trials. Photodiagn Photodyn Ther 53:104558","journal-title":"Photodiagn Photodyn Ther"},{"issue":"1","key":"5064_CR76","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1007\/s40520-024-02853-0","volume":"36","author":"T Fan","year":"2024","unstructured":"Fan T, Li Y, Wong AYL, Liang X, Yuan Y, Xia P et al (2024) A systematic review and network meta-analysis on the optimal wavelength of low-level light therapy (LLLT) in treating knee osteoarthritis symptoms. Aging Clin Exp Res 36(1):203","journal-title":"Aging Clin Exp Res"},{"issue":"3","key":"5064_CR77","doi-asserted-by":"crossref","first-page":"e20210138","DOI":"10.1590\/2317-1782\/20212021138","volume":"34","author":"CF Guedes Pereira M\u00e1ximo","year":"2022","unstructured":"Guedes Pereira M\u00e1ximo CF, Co\u00ealho JF, Benevides SD, Alves G\u00c2DS (2022) Effects of low-level laser photobiomodulation on the masticatory function and mandibular movements in adults with temporomandibular disorder: a systematic review with meta-analysis. CoDAS 34(3):e20210138","journal-title":"CoDAS"},{"issue":"12","key":"5064_CR78","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.3390\/brainsci14121179","volume":"14","author":"A Jim\u00e9nez","year":"2024","unstructured":"Jim\u00e9nez A, Carrick FR, Hoffman N, Jemni M (2024) The Impact of Low-Level Laser Therapy on Spasticity in Children with Spastic Cerebral Palsy: A Systematic Review. Brain Sci 14(12):1179","journal-title":"Brain Sci"},{"issue":"5","key":"5064_CR79","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1007\/s10103-020-03197-7","volume":"36","author":"G Jing","year":"2021","unstructured":"Jing G, Zhao Y, Dong F, Zhang P, Ren H, Liu J et al (2021) Effects of different energy density low-level laser therapies for temporomandibular joint disorders patients: a systematic review and network meta-analysis of parallel randomized controlled trials. Lasers Med Sci 36(5):1101\u20131108","journal-title":"Lasers Med Sci"},{"issue":"9","key":"5064_CR80","doi-asserted-by":"crossref","first-page":"e0291345","DOI":"10.1371\/journal.pone.0291345","volume":"18","author":"I Lourinho","year":"2023","unstructured":"Lourinho I, Sousa T, Jardim R, Pinto AC, Iosimuta N (2023) Effects of low-level laser therapy in adults with rheumatoid arthritis: A systematic review and meta-analysis of controlled trials. PLoS ONE 18(9):e0291345","journal-title":"PLoS ONE"},{"issue":"1","key":"5064_CR81","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1080\/08990220.2022.2157387","volume":"40","author":"S Malik","year":"2023","unstructured":"Malik S, Sharma S, Dutta N, Khurana D, Sharma RK, Sharma S (2023) Effect of low-level laser therapy plus exercise therapy on pain, range of motion, muscle strength, and function in knee osteoarthritis - a systematic review and meta-analysis. Somatosens Mot Res 40(1):8\u201324","journal-title":"Somatosens Mot Res"},{"issue":"3","key":"5064_CR82","doi-asserted-by":"crossref","first-page":"287","DOI":"10.11607\/ofph.2032","volume":"32","author":"FM Munguia","year":"2018","unstructured":"Munguia FM, Jang J, Salem M, Clark GT, Enciso R (2018) Efficacy of Low-Level Laser Therapy in the Treatment of Temporomandibular Myofascial Pain: A Systematic Review and Meta-Analysis. J Oral Facial Pain Headache 32(3):287\u2013297","journal-title":"J Oral Facial Pain Headache"},{"key":"5064_CR83","doi-asserted-by":"crossref","unstructured":"Rankin IA, Sargeant H, Rehman H, Gurusamy KS (2017) Low-level laser therapy for carpal tunnel syndrome. Cochrane Database Syst Reviews 2017(8):CD012765","DOI":"10.1002\/14651858.CD012765"},{"issue":"2","key":"5064_CR84","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1111\/joor.13230","volume":"49","author":"H Ren","year":"2022","unstructured":"Ren H, Liu J, Liu Y, Yu C, Bao G, Kang H (2022) Comparative effectiveness of low-level laser therapy with different wavelengths and transcutaneous electric nerve stimulation in the treatment of pain caused by temporomandibular disorders: A systematic review and network meta-analysis. J Oral Rehabil 49(2):138\u2013149","journal-title":"J Oral Rehabil"},{"issue":"10","key":"5064_CR85","doi-asserted-by":"crossref","first-page":"e031142","DOI":"10.1136\/bmjopen-2019-031142","volume":"9","author":"MB Stausholm","year":"2019","unstructured":"Stausholm MB, Naterstad IF, Joensen J, Lopes-Martins R\u00c1B, S\u00e6b\u00f8 H, Lund H et al (2019) Efficacy of low-level laser therapy on pain and disability in knee osteoarthritis: systematic review and meta-analysis of randomised placebo-controlled trials. BMJ Open 9(10):e031142","journal-title":"BMJ Open"},{"issue":"1","key":"5064_CR86","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/s13102-021-00306-z","volume":"13","author":"N Tripodi","year":"2021","unstructured":"Tripodi N, Feehan J, Husaric M, Sidiroglou F, Apostolopoulos V (2021) The effect of low-level red and near-infrared photobiomodulation on pain and function in tendinopathy: a systematic review and meta-analysis of randomized control trials. BMC Sports Sci Med Rehabil 13(1):91","journal-title":"BMC Sports Sci Med Rehabil"},{"issue":"3","key":"5064_CR87","doi-asserted-by":"crossref","first-page":"e14088","DOI":"10.1097\/MD.0000000000014088","volume":"98","author":"W Wang","year":"2019","unstructured":"Wang W, Jiang W, Tang C, Zhang X, Xiang J (2019) Clinical efficacy of low-level laser therapy in plantar fasciitis: A systematic review and meta-analysis. Med (Baltim) 98(3):e14088","journal-title":"Med (Baltim)"},{"issue":"6","key":"5064_CR88","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1177\/10538127251339104","volume":"38","author":"BWD Yap","year":"2025","unstructured":"Yap BWD, Lim ECW (2025) Shedding more light on the short-term effect of low-level laser therapy on pain in tendinopathy: A systematic review with meta-analysis. J Back Musculoskelet Rehabilitation 38(6):1232\u20131256","journal-title":"J Back Musculoskelet Rehabilitation"},{"issue":"3","key":"5064_CR89","first-page":"241","volume":"22","author":"SW Yeh","year":"2019","unstructured":"Yeh SW, Hong CH, Shih MC, Tam KW, Huang YH, Kuan YC (2019) Low-Level Laser Therapy for Fibromyalgia: A Systematic Review and Meta-Analysis. Pain Physician 22(3):241\u2013254","journal-title":"Pain Physician"},{"key":"5064_CR90","doi-asserted-by":"crossref","unstructured":"Yousefi-Nooraie R, Schonstein E, Heidari K, Rashidian A, Pennick V, Akbari\u2010Kamrani M et al (2008) Low level laser therapy for nonspecific low\u2010back pain. Cochrane Database Syst Reviews 2008(2):CD005107","DOI":"10.1002\/14651858.CD005107.pub4"},{"issue":"6","key":"5064_CR91","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1007\/s10103-019-02722-7","volume":"34","author":"F Anschau","year":"2019","unstructured":"Anschau F, Webster J, Capra MEZ, de Azeredo da Silva ALF, Stein AT (2019) Efficacy of low-level laser for treatment of cancer oral mucositis: a systematic review and meta-analysis. Lasers Med Sci 34(6):1053\u20131062","journal-title":"Lasers Med Sci"},{"issue":"8","key":"5064_CR92","first-page":"1413","volume":"59","author":"R Franco","year":"2023","unstructured":"Franco R, Lupi E, Iacomino E, Galeotti A, Capogreco M, Santos JMM et al (2023) Low-Level Laser Therapy for the Treatment of Oral Mucositis Induced by Hematopoietic Stem Cell Transplantation: A Systematic Review with Meta-Analysis. Med (Kaunas) 59(8):1413","journal-title":"Med (Kaunas)"},{"issue":"2","key":"5064_CR93","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1007\/s10103-021-03392-0","volume":"37","author":"A Gole\u017e","year":"2022","unstructured":"Gole\u017e A, Frange\u017e I, Cankar K, Frange\u017e HB, Ovsenik M, Nemeth L (2022) Effects of low-level light therapy on xerostomia related to hyposalivation: a systematic review and meta-analysis of clinical trials. Lasers Med Sci 37(2):745\u2013758","journal-title":"Lasers Med Sci"},{"issue":"1","key":"5064_CR94","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1007\/s00431-017-3043-4","volume":"177","author":"M He","year":"2018","unstructured":"He M, Zhang B, Shen N, Wu N, Sun J (2018) A systematic review and meta-analysis of the effect of low-level laser therapy (LLLT) on chemotherapy-induced oral mucositis in pediatric and young patients. Eur J Pediatr 177(1):7\u201317","journal-title":"Eur J Pediatr"},{"issue":"3","key":"5064_CR95","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.oooo.2025.04.095","volume":"140","author":"B Joseph","year":"2025","unstructured":"Joseph B, Mauramo M, Sorsa T, Anil S, Waltimo T (2025) LED-based low-level light therapy for oral mucositis in cancer patients: a systematic review and GRADE analysis. Oral Surgery, Oral Medicine. Oral Pathol Oral Radiol 140(3):300\u2013311","journal-title":"Oral Pathol Oral Radiol"},{"issue":"2","key":"5064_CR96","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1007\/s00520-024-08325-5","volume":"32","author":"L Nascimento Ribeiro","year":"2024","unstructured":"Nascimento Ribeiro L, de Vasconcelos Carvalho M, de Oliveira Limirio JPJ, do Egito Vasconcelos BC, Moraes SLD, Pellizzer EP (2024) Impact of low-level laser therapy on the quality of life of patients with xerostomia undergoing head and neck radiotherapy: a systematic review. Support Care Cancer 32(2):118","journal-title":"Support Care Cancer"},{"key":"5064_CR97","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.critrevonc.2019.03.009","volume":"138","author":"M Peralta-Mamani","year":"2019","unstructured":"Peralta-Mamani M, da Silva BM, da Silva Pinto AC, Rubira-Bullen IRF, Hon\u00f3rio HM, Rubira CMF et al (2019) Low-level laser therapy dosimetry most used for oral mucositis due to radiotherapy for head and neck cancer: a systematic review and meta-analysis. Crit Rev Oncol Hematol 138:14\u201323","journal-title":"Crit Rev Oncol Hematol"},{"key":"5064_CR98","doi-asserted-by":"crossref","first-page":"104524","DOI":"10.1016\/j.oraloncology.2019.104524","volume":"102","author":"VH Souza de Lima","year":"2020","unstructured":"Souza de Lima VH, de Oliveira-Neto OB, da Hora Sales PH, da Silva Torres T, de Lima FJC (2020) Effectiveness of low-level laser therapy for oral mucositis prevention in patients undergoing chemoradiotherapy for the treatment of head and neck cancer: A systematic review and meta-analysis. Oral Oncol 102:104524","journal-title":"Oral Oncol"},{"issue":"1","key":"5064_CR99","doi-asserted-by":"crossref","first-page":"2447355","DOI":"10.1080\/09546634.2024.2447355","volume":"36","author":"A Alosaimi","year":"2025","unstructured":"Alosaimi A, Algarni A, Alharbi A, Alotaibi A, Alomairi A, Alsurayhi M et al (2025) Comparative efficacy of minoxidil alone versus minoxidil combined with low-level laser therapy in the treatment of androgenic alopecia: a systematic review and meta-analysis. J Dermatolog Treat 36(1):2447355","journal-title":"J Dermatolog Treat"},{"issue":"4","key":"5064_CR100","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1080\/14764172.2017.1400170","volume":"20","author":"SW Delaney","year":"2018","unstructured":"Delaney SW, Zhang P (2018) Systematic review of low-level laser therapy for adult androgenic alopecia. J Cosmet Laser Ther 20(4):229\u2013236","journal-title":"J Cosmet Laser Ther"},{"issue":"2","key":"5064_CR101","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1089\/fpsam.2021.0151","volume":"26","author":"P Gentile","year":"2024","unstructured":"Gentile P, Garcovich S (2024) The Effectiveness of Low-Level Light\/Laser Therapy on Hair Loss. Facial Plast Surg aesthetic Med 26(2):228\u2013235","journal-title":"Facial Plast Surg aesthetic Med"},{"issue":"3","key":"5064_CR102","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1177\/1534734620914439","volume":"20","author":"CM dos Santos","year":"2021","unstructured":"dos Santos CM, Rocha RBD, Hazime FA, Cardoso VS (2021) A Systematic Review and Meta-Analysis of the Effects of Low-Level Laser Therapy in the Treatment of Diabetic Foot Ulcers. Int J Low Extrem Wounds 20(3):198\u2013207","journal-title":"Int J Low Extrem Wounds"},{"key":"5064_CR103","first-page":"e","volume":"47","author":"MVC Gaitero","year":"2025","unstructured":"Gaitero MVC, de Mira TAA, Gondim EJL, do Nascimento SL, Surita FG (2025) Low-level laser therapy for nipple trauma and pain during breastfeeding: systematic review and meta-analysis. Rev bras ginecol obstet 47:e\u2013rbgo3","journal-title":"Rev bras ginecol obstet"},{"key":"5064_CR104","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.diabres.2018.07.014","volume":"143","author":"S Li","year":"2018","unstructured":"Li S, Wang C, Wang B, Liu L, Tang L, Liu D et al (2018) Efficacy of low-level light therapy for treatment of diabetic foot ulcer: A systematic review and meta-analysis of randomized controlled trials. Diabetes Res Clin Pract 143:215\u2013224","journal-title":"Diabetes Res Clin Pract"},{"issue":"4","key":"5064_CR105","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1007\/s10103-017-2150-9","volume":"32","author":"RS Machado","year":"2017","unstructured":"Machado RS, Viana S, Sbruzzi G (2017) Low-level laser therapy in the treatment of pressure ulcers: systematic review. Lasers Med Sci 32(4):937\u2013944","journal-title":"Lasers Med Sci"},{"issue":"10","key":"5064_CR106","first-page":"e72542","volume":"16","author":"N Taha","year":"2024","unstructured":"Taha N, Daoud H, Malik T, Shettysowkoor J, Rahman S (2024) The Effects of Low-Level Laser Therapy on Wound Healing and Pain Management in Skin Wounds: A Systematic Review and Meta-Analysis. Cureus 16(10):e72542","journal-title":"Cureus"},{"issue":"2","key":"5064_CR107","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1111\/wrr.12399","volume":"24","author":"CN Tchanque-Fossuo","year":"2016","unstructured":"Tchanque-Fossuo CN, Ho D, Dahle SE, Koo E, Li CS, Isseroff RR et al (2016) A systematic review of low-level light therapy for treatment of diabetic foot ulcer. Wound Repair Regen 24(2):418\u2013426","journal-title":"Wound Repair Regen"},{"issue":"11","key":"5064_CR108","doi-asserted-by":"crossref","first-page":"3771","DOI":"10.31557\/APJCP.2024.25.11.3771","volume":"25","author":"DI Wahid","year":"2024","unstructured":"Wahid DI, Wahyono RA, Setiaji K, Hardiyanto H, Suwardjo S, Anwar SL et al (2024) The Effication of Low-Level Laser Therapy, Kinesio Taping, and Endermology on Post-Mastectomy Lymphedema: A Systematic Review and Meta-Analysis. Asian Pac J Cancer Prev 25(11):3771\u20133779","journal-title":"Asian Pac J Cancer Prev"},{"issue":"1","key":"5064_CR109","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/wrr.12871","volume":"29","author":"Y Zhou","year":"2021","unstructured":"Zhou Y, Chia HWA, Tang HWK, Lim SYJ, Toh WY, Lim XL et al (2021) Efficacy of low-level light therapy for improving healing of diabetic foot ulcers: A systematic review and meta-analysis of randomized controlled trials. Wound Repair Regen 29(1):34\u201344","journal-title":"Wound Repair Regen"},{"issue":"Suppl 2","key":"5064_CR110","first-page":"S203","volume":"72","author":"B Deng","year":"2024","unstructured":"Deng B, Zhou M, Kong X, Luo L, Lv H (2024) A meta-analysis of randomized controlled trials evaluating the effectiveness and safety of the repeated low-level red light therapy in slowing the progression of myopia in children and adolescents. Indian J Ophthalmol 72(Suppl 2):S203\u2013S10","journal-title":"Indian J Ophthalmol"},{"key":"5064_CR111","doi-asserted-by":"crossref","unstructured":"Henein C, Steel DHW (2021) Photobiomodulation for non-exudative age\u2010related macular degeneration. Cochrane Database Syst Reviews 2021(5):CD013029","DOI":"10.1002\/14651858.CD013029.pub2"},{"key":"5064_CR112","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.ajo.2023.03.036","volume":"252","author":"J Tang","year":"2023","unstructured":"Tang J, Liao Y, Yan N, Dereje SB, Wang J, Luo Y et al (2023) Efficacy of Repeated Low-Level Red-Light Therapy for Slowing the Progression of Childhood Myopia: A Systematic Review and Meta-analysis. Am J Ophthalmol 252:153\u2013163","journal-title":"Am J Ophthalmol"},{"issue":"5","key":"5064_CR113","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1080\/08820538.2025.2452885","volume":"40","author":"X Yang","year":"2025","unstructured":"Yang X, Yao L, Sun G, Zhang H, Yu H, Bai H (2025) Low-Level Red Light for the Progression Myopia in Children: A Meta-Analysis. Semin Ophthalmol 40(5):358\u2013363","journal-title":"Semin Ophthalmol"},{"key":"5064_CR114","doi-asserted-by":"crossref","unstructured":"Vlassov VV, Reze AG (2006) Low level laser therapy for treating tuberculosis. Cochrane Database Syst Reviews 2006(2):CD0034","DOI":"10.1002\/14651858.CD003490.pub2"},{"issue":"12","key":"5064_CR115","doi-asserted-by":"crossref","first-page":"931","DOI":"10.3390\/brainsci10120931","volume":"10","author":"CH Chen","year":"2020","unstructured":"Chen CH, Huang CY, Chang CY, Cheng YF (2020) Efficacy of Low-Level Laser Therapy for Tinnitus: A Systematic Review with Meta-Analysis and Trial Sequential Analysis. Brain Sci 10(12):931","journal-title":"Brain Sci"},{"issue":"10","key":"5064_CR116","doi-asserted-by":"publisher","first-page":"3969","DOI":"10.1007\/s00520-019-04890-2","volume":"27","author":"Y Zadik","year":"2019","unstructured":"Zadik Y, Arany PR, Fregnani ER, Bossi P, Antunes HS, Bensadoun RJ et al (2019) Systematic review of photobiomodulation for the management of oral mucositis in cancer patients and clinical practice guidelines. Support Care Cancer 27(10):3969\u20133983","journal-title":"Support Care Cancer"},{"issue":"4","key":"5064_CR117","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1016\/j.jds.2025.06.002","volume":"20","author":"R Bahrami","year":"2025","unstructured":"Bahrami R, Eftekharian S, Jafarieh R, Pourhajibagher M, Bahador A (2025) The potential effect of photobiomodulation on oral mucositis induced by head and neck radio-chemotherapy: A literature review. J Dent Sci 20(4):2039\u20132045","journal-title":"J Dent Sci"},{"issue":"9","key":"5064_CR118","doi-asserted-by":"crossref","first-page":"763","DOI":"10.12968\/denu.2014.41.9.763","volume":"41","author":"MR Milward","year":"2014","unstructured":"Milward MR, Holder MJ, Palin WM, Hadis MA, Carroll JD, Cooper PR (2014) Low Level Light Therapy (LLLT) for the treatment and management of dental and oral diseases. Dent Update 41(9):763\u2013772","journal-title":"Dent Update"},{"key":"5064_CR119","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s41547-025-00312-1","volume":"9","author":"BP Kumar","year":"2025","unstructured":"Kumar BP, Devi VV, Nazreen SA (2025) Photobiomodulation therapy in oral and maxillofacial surgery: Narrative review of biological mechanisms and clinical applications. Lasers Dent Sci 9:37","journal-title":"Lasers Dent Sci"},{"issue":"1","key":"5064_CR120","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.cct.2012.10.009","volume":"34","author":"AL Peterson","year":"2013","unstructured":"Peterson AL, Roache JD, Raj J, Young-McCaughan S (2013) The need for expanded monitoring of adverse events in behavioral health clinical trials. Contemp Clin Trials 34(1):152\u2013154","journal-title":"Contemp Clin Trials"},{"key":"5064_CR121","doi-asserted-by":"crossref","first-page":"e073725","DOI":"10.1136\/bmj-2022-073725","volume":"381","author":"DR Junqueira","year":"2023","unstructured":"Junqueira DR, Zorzela L, Golder S, Loke Y, Gagnier JJ, Julious SA et al (2023) CONSORT Harms 2022 statement, explanation, and elaboration: updated guideline for the reporting of harms in randomised trials. BMJ 381:e073725","journal-title":"BMJ"}],"container-title":["Lasers in Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-026-05064-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10103-026-05064-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10103-026-05064-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:20:37Z","timestamp":1792066837000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10103-026-05064-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,15]]},"references-count":121,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["5064"],"URL":"https:\/\/doi.org\/10.1007\/s10103-026-05064-3","relation":{},"ISSN":["1435-604X"],"issn-type":[{"value":"1435-604X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,15]]},"assertion":[{"value":"7 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 October 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This umbrella review does not involve the collection of primary data from human participants or animals. Therefore, ethical approval and informed consent were not required.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"259"}}