{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:28:07Z","timestamp":1791998887860,"version":"4.4.0"},"reference-count":96,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2006,11,24]],"date-time":"2006-11-24T00:00:00Z","timestamp":1164326400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastric Cancer"],"published-print":{"date-parts":[[2006,11,24]]},"DOI":"10.1007\/s10120-006-0397-0","type":"journal-article","created":{"date-parts":[[2006,11,27]],"date-time":"2006-11-27T08:04:08Z","timestamp":1164614648000},"page":"245-253","source":"Crossref","is-referenced-by-count":218,"title":["Gastric cancer screening using the serum pepsinogen test method"],"prefix":"10.1007","volume":"9","author":[{"given":"Kazumasa","family":"Miki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,11,24]]},"reference":[{"key":"397_CR1","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1111\/j.1349-7006.1988.tb01537.x","volume":"79","author":"SC Huang","year":"1988","journal-title":"Jpn J Cancer Res"},{"key":"397_CR2","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1002\/ijc.2910380608","volume":"38","author":"A Oshima","year":"1986","journal-title":"Int J Cancer"},{"key":"397_CR3","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/ijc.2910600106","volume":"60","author":"A Fukao","year":"1995","journal-title":"Int J Cancer"},{"key":"397_CR4","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/BF02774209","volume":"22","author":"K Miki","year":"1987","journal-title":"Gastroenterol Jpn"},{"key":"397_CR5","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1111\/j.1349-7006.1993.tb02805.x","volume":"84","author":"K Miki","year":"1993","journal-title":"Jpn J Cancer Res"},{"key":"397_CR6","first-page":"87","volume-title":"Cancer screening. A practical guide for physicians","author":"M Ichinose","year":"2001"},{"key":"397_CR7","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1111\/j.1572-0241.2003.07410.x","volume":"98","author":"K Miki","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"397_CR8","first-page":"56","volume-title":"Pepsinogen test method","author":"T Shiga","year":"1998"},{"key":"397_CR9","first-page":"139","volume-title":"Aspartic proteinases: structure, function, biology and biomedical implications","author":"K Miki","year":"1995"},{"key":"397_CR10","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1002\/1097-0142(19940601)73:11<2695::AID-CNCR2820731108>3.0.CO;2-O","volume":"73","author":"S Kikuchi","year":"1994","journal-title":"Cancer"},{"key":"397_CR11","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1136\/gut.44.5.693","volume":"44","author":"F Kitahara","year":"1999","journal-title":"Gut"},{"key":"397_CR12","first-page":"87","volume-title":"Progress in gastric cancer research 1997","author":"K Miki","year":"1997"},{"key":"397_CR13","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/j.1349-7006.2005.00098.x","volume":"96","author":"H Ohata","year":"2005","journal-title":"Cancer Sci"},{"key":"397_CR14","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0016-5085(19)33596-6","volume":"61","author":"IM Samloff","year":"1971","journal-title":"Gastroenterology"},{"key":"397_CR15","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S0016-5085(19)33138-5","volume":"65","author":"IM Samloff","year":"1973","journal-title":"Gastroenterology"},{"key":"397_CR16","first-page":"78","volume-title":"Gastric malignant tumor","author":"K Miki","year":"2000"},{"key":"397_CR17","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1007\/BF01308327","volume":"25","author":"GN Stemmermann","year":"1980","journal-title":"Dig Dis Sci"},{"key":"397_CR18","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1349-7006.1989.tb02276.x","volume":"80","author":"K Miki","year":"1989","journal-title":"Jpn J Cancer Res"},{"key":"397_CR19","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1007\/BF02347560","volume":"30","author":"A Kodoi","year":"1995","journal-title":"J Gastroenterol"},{"key":"397_CR20","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/apm.1965.64.1.31","volume":"64","author":"P Lauren","year":"1965","journal-title":"Acta Path Microbiol Scand"},{"key":"397_CR21","first-page":"6735","volume":"52","author":"P Correa","year":"1992","journal-title":"Cancer Res"},{"key":"397_CR22","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/BF00051709","volume":"4","author":"A Fukao","year":"1993","journal-title":"Cancer Causes Control"},{"key":"397_CR23","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2188\/jea.3.35","volume":"3","author":"M Kabuto","year":"1993","journal-title":"J Epidemiol"},{"key":"397_CR24","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1093\/oxfordjournals.aje.a010282","volume":"151","author":"T Namekata","year":"2000","journal-title":"Am J Epidemiol"},{"key":"397_CR25","doi-asserted-by":"crossref","first-page":"537","DOI":"10.7326\/0003-4819-93-4-537","volume":"93","author":"AMY Nomura","year":"1980","journal-title":"Ann Intern Med"},{"key":"397_CR26","first-page":"564","volume":"24","author":"MT Fahey","year":"2000","journal-title":"Cancer Detect Prev"},{"key":"397_CR27","first-page":"45","volume":"1","author":"D Palli","year":"1993","journal-title":"Cancer Epidem Biomar Prev"},{"key":"397_CR28","first-page":"461","volume":"2","author":"J Parsonnet","year":"1993","journal-title":"Cancer Epidem Biomar Prev"},{"key":"397_CR29","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0009-8981(87)90022-2","volume":"163","author":"GN Stemmermann","year":"1987","journal-title":"Clin Chim Acta"},{"key":"397_CR30","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0009-8981(87)90324-X","volume":"169","author":"K Matsusako","year":"1987","journal-title":"Clin Chim Acta"},{"key":"397_CR31","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/00042737-200202000-00005","volume":"14","author":"M Ito","year":"2002","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"397_CR32","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/0016-5085(82)90176-7","volume":"82","author":"IM Samloff","year":"1982","journal-title":"Gastroenterology"},{"key":"397_CR33","first-page":"1091","volume":"19","author":"A Tamm","year":"1984","journal-title":"Scand J Gastroenterol"},{"key":"397_CR34","first-page":"107","volume":"10","author":"C Ley","year":"2001","journal-title":"Cancer Epidem Biomar Prev"},{"key":"397_CR35","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1093\/oxfordjournals.aje.a008901","volume":"144","author":"A Aromaa","year":"1996","journal-title":"Am J Epidemiol"},{"key":"397_CR36","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/0016-5085(92)90156-S","volume":"102","author":"M Asaka","year":"1992","journal-title":"Gastroenterology"},{"key":"397_CR37","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/0016-5085(94)90535-5","volume":"107","author":"PM Webb","year":"1994","journal-title":"Gastroenterology"},{"key":"397_CR38","first-page":"839","volume":"91","author":"S Yoshida","year":"1996","journal-title":"Am J Gastroenterol"},{"key":"397_CR39","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1258\/0969141041732184","volume":"11","author":"M Dinis-Ribeiro","year":"2004","journal-title":"J Med Screen"},{"key":"397_CR40","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0009-8981(82)90034-1","volume":"126","author":"M Ichinose","year":"1982","journal-title":"Clin Chim Acta"},{"key":"397_CR41","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/0016-5085(82)90118-4","volume":"82","author":"IM Samloff","year":"1982","journal-title":"Gastroenterology"},{"key":"397_CR42","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0009-8981(88)90033-2","volume":"175","author":"SC Huang","year":"1988","journal-title":"Clin Chim Acta"},{"key":"397_CR43","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1136\/jcp.48.4.364","volume":"48","author":"N Konishi","year":"1995","journal-title":"J Clin Pathol"},{"key":"397_CR44","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1111\/j.1349-7006.1995.tb03317.x","volume":"86","author":"Y Hattori","year":"1995","journal-title":"Jpn J Cancer Res"},{"key":"397_CR45","volume-title":"Pepsinogen handbook","year":"2001"},{"key":"397_CR46","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1080\/003655299750025309","volume":"34","author":"K Bodger","year":"1999","journal-title":"Scand J Gastroenterol"},{"key":"397_CR47","doi-asserted-by":"crossref","first-page":"884","DOI":"10.3109\/00365529209000158","volume":"27","author":"FY Chang","year":"1992","journal-title":"Scand J Gastroenterol"},{"key":"397_CR48","first-page":"627","volume":"5","author":"L Zhang","year":"1996","journal-title":"Cancer Epid Biomar Prev"},{"key":"397_CR49","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1038\/bjc.1996.144","volume":"73","author":"T Knight","year":"1996","journal-title":"Br J Cancer"},{"key":"397_CR50","first-page":"261","volume":"7","author":"M Inoue","year":"1998","journal-title":"Cancer Epidem Biomar Prev"},{"key":"397_CR51","first-page":"119","volume":"2","author":"F Sitas","year":"1993","journal-title":"Cancer Epidem Biomar Prev"},{"key":"397_CR52","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1080\/003655200750023138","volume":"35","author":"A Oksanen","year":"2000","journal-title":"Scand J Gastroenterol"},{"key":"397_CR53","doi-asserted-by":"crossref","first-page":"109","DOI":"10.3109\/00365529109103997","volume":"186","author":"M Kekki","year":"1991","journal-title":"Scand J Gastroenterol"},{"key":"397_CR54","doi-asserted-by":"crossref","first-page":"117","DOI":"10.3109\/00365529109103998","volume":"186","author":"K Varis","year":"1991","journal-title":"Scand J Gastroenterol"},{"key":"397_CR55","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0009-8981(02)00040-2","volume":"320","author":"E Mardh","year":"2002","journal-title":"Clin Chim Acta"},{"key":"397_CR56","first-page":"1122","volume":"16","author":"K Miki","year":"1989","journal-title":"Gan To Kagaku Ryoho"},{"key":"397_CR57","first-page":"905","volume":"21","author":"H Fukunaga","year":"1989","journal-title":"Igaku-To-Yakugaku (J Med Pharm Sci)"},{"key":"397_CR58","doi-asserted-by":"crossref","first-page":"654","DOI":"10.2169\/naika.81.654","volume":"81","author":"K Miki","year":"1992","journal-title":"Nippon Naika Gakkai Zasshi"},{"key":"397_CR59","first-page":"1127","volume":"26","author":"Y Kimura","year":"1999","journal-title":"Kaku Igaku"},{"key":"397_CR60","first-page":"1591","volume":"36","author":"G Yamaki","year":"2001","journal-title":"Stomach and Intestine"},{"issue":"Suppl. III","key":"397_CR61","first-page":"A185","volume":"51","author":"M Dinis-Ribeiro","year":"2002","journal-title":"Gut"},{"key":"397_CR62","first-page":"113","volume":"2","author":"WC You","year":"1993","journal-title":"Cancer Epidem Biomar Prev"},{"key":"397_CR63","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1093\/ije\/24.2.346","volume":"24","author":"S Kikuchi","year":"1995","journal-title":"Int J Epidemiol"},{"key":"397_CR64","first-page":"1211","volume":"89","author":"S Wagner","year":"1994","journal-title":"Am J Gastroenterol"},{"key":"397_CR65","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1046\/j.1440-1746.2000.02077.x","volume":"15","author":"A Ogihara","year":"2000","journal-title":"J Gastroenterol Hepatol"},{"key":"397_CR66","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1007\/BF01297088","volume":"38","author":"FM Hunter","year":"1993","journal-title":"Dig Dis Sci"},{"key":"397_CR67","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1136\/jcp.46.9.826","volume":"46","author":"G Biasco","year":"1993","journal-title":"J Clin Pathol"},{"key":"397_CR68","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0016-5085(99)70122-8","volume":"116","author":"PM Webb","year":"1999","journal-title":"Gastroenterology"},{"key":"397_CR69","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1136\/gut.37.2.199","volume":"37","author":"RJ Schlemper","year":"1995","journal-title":"Gut"},{"key":"397_CR70","first-page":"139","volume":"173","author":"JG Goedhard","year":"1985","journal-title":"Prog Clin Biol Res"},{"key":"397_CR71","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1002\/ijc.2910620504","volume":"62","author":"I Kato","year":"1995","journal-title":"Int J Cancer"},{"key":"397_CR72","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1111\/j.1572-0241.1998.00335.x","volume":"93","author":"M Yoshihara","year":"1998","journal-title":"Am J Gastroenterol"},{"key":"397_CR73","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1080\/00365529850170892","volume":"33","author":"K Varis","year":"1998","journal-title":"Scand J Gastroenterol"},{"key":"397_CR74","first-page":"2739","volume":"15","author":"M-S Wu","year":"1995","journal-title":"Anticancer Res"},{"key":"397_CR75","first-page":"194","volume":"223","author":"F Farinati","year":"1991","journal-title":"Ital J Gastroenterol"},{"key":"397_CR76","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/0016-5085(91)90724-Y","volume":"101","author":"M Goldschmiedt","year":"1991","journal-title":"Gastroenterology"},{"key":"397_CR77","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1136\/gut.40.1.42","volume":"40","author":"MT Serrono","year":"1997","journal-title":"Gut"},{"key":"397_CR78","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1136\/gut.50.1.13","volume":"50","author":"S Lorente","year":"2002","journal-title":"Gut"},{"key":"397_CR79","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1111\/j.1349-7006.1995.tb02989.x","volume":"86","author":"H Fukuda","year":"1995","journal-title":"Jpn J Cancer Res"},{"key":"397_CR80","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1080\/003655200750023011","volume":"35","author":"K Varis","year":"2000","journal-title":"Scand J Gastroenterol"},{"key":"397_CR81","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/j.1349-7006.2000.tb00969.x","volume":"91","author":"S Kikuchi","year":"2000","journal-title":"Jpn J Cancer Res"},{"key":"397_CR82","first-page":"961","volume":"9","author":"M Plummer","year":"2000","journal-title":"Cancer Epidem Biomar Prev"},{"key":"397_CR83","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1002\/ijc.11680","volume":"109","author":"H Ohata","year":"2004","journal-title":"Int J Cancer"},{"key":"397_CR84","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1136\/gut.2004.055400","volume":"54","author":"H Watabe","year":"2005","journal-title":"Gut"},{"key":"397_CR85","unstructured":"Fujishiro M, Yahagi N, Kakushima N, Kodashima S, Nakamura M, Kobayashi K, et al. Early detection of asymptomatic gastric cancers using serum pepsinogen levels to indicate endoscopic submucosal dissection for better quality of life. Proceeding of 6th International Gastric Cancer Congress. Yokohama 2005;145\u201350"},{"key":"397_CR86","first-page":"1555","volume":"17","author":"M Sasajima","year":"2002","journal-title":"Clin Gastroenterol"},{"key":"397_CR87","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/PL00011692","volume":"3","author":"Y Tsubono","year":"2000","journal-title":"Gastric Cancer"},{"key":"397_CR88","unstructured":"Miki K. Annual report of the Research Committee of the Study of High Risk Strategy of Gastric Cancer Screening, supported by a Grant-in-Aid for the Research from the Ministry of Health, Labour and Welfare, Japan. Tokyo; 2005(April). p. 1\u2013288 (in Japanese)"},{"key":"397_CR89","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1046\/j.1443-1661.2000.00004.x","volume":"12","author":"M Muto","year":"2000","journal-title":"Dig Endosc"},{"key":"397_CR90","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1023\/A:1026633913154","volume":"44","author":"K Ozasa","year":"1999","journal-title":"Dig Dis Sci"},{"key":"397_CR91","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1023\/A:1018833819860","volume":"42","author":"Y Watanabe","year":"1997","journal-title":"Dig Dis Sci"},{"key":"397_CR92","doi-asserted-by":"crossref","first-page":"2691","DOI":"10.1002\/1097-0142(19940601)73:11<2691::AID-CNCR2820731107>3.0.CO;2-2","volume":"73","author":"M Asaka","year":"1994","journal-title":"Cancer"},{"key":"397_CR93","unstructured":"Asaka M, Kato M, Kudo M, Katagiri M, Nishikawa K, Yoshida J, et al. Relationship between Helicobacter pylori infection, atrophic gastritis and gastric carcinoma in a Japanese population. Eur J Gastroenterol Hepatol 1995;s7\u201310"},{"key":"397_CR94","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1086\/430353","volume":"191","author":"AMY Nomura","year":"2005","journal-title":"J Infect Dis"},{"issue":"Suppl. VII","key":"397_CR95","first-page":"A 70","volume":"54","author":"K Miki","year":"2005","journal-title":"Gut"},{"key":"397_CR96","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/nrc1433","volume":"4","author":"M Hatakeyama","year":"2004","journal-title":"Nature Rev Cancer"}],"container-title":["Gastric Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10120-006-0397-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10120-006-0397-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10120-006-0397-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,18]],"date-time":"2020-04-18T23:32:59Z","timestamp":1587252779000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10120-006-0397-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,11,24]]},"references-count":96,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,11,24]]}},"alternative-id":["397"],"URL":"https:\/\/doi.org\/10.1007\/s10120-006-0397-0","relation":{},"ISSN":["1436-3291","1436-3305"],"issn-type":[{"value":"1436-3291","type":"print"},{"value":"1436-3305","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,11,24]]}}}