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YM has received honorarium from Ono Pharmaceutical Co., Ltd.; Bristol Myers Squib Japan K.K.;Merk & Co., Inc.; and Astellas Pharma Inc. RM has received honorarium from Kaken Pharmaceutical Co., Ltd.; MC medical, Inc.; Johnson and Johnson K.K.; Medtronic Japan Co., Ltd.; Intuitive Japan Inc.; and Olympus Co., Ltd. MT has received honorarium from Taiho Pharmaceutical Co., Ltd.; Chugai Pharmaceutical Co., Ltd.; Ono Pharmaceutical Co., Ltd.; Bristol Myers Squib Japan K.K.; Yakult Honsha Co., Ltd.; Takeda Pharmaceutical Co., Ltd.; Eli Lilly Japan K.K.; Pfizer Japan Inc.; Daiichi Sankyo Ltd.; Johnson and Johnson K.K.; Medtronic Japan Co., Ltd.; Intuitive Japan Inc.; and Olympus Co., Ltd.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures were conducted in accordance with the ethical standards of the relevant institutional and national committees on human experimentation, as well as the 1964 Declaration of Helsinki and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}