{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T06:19:43Z","timestamp":1787897983323,"version":"build-2784847793"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP266f0137011"],"award-info":[{"award-number":["JP266f0137011"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Gastric Cancer"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1007\/s10120-026-01783-2","type":"journal-article","created":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T06:26:55Z","timestamp":1785306415000},"page":"1166-1174","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Modified transferrin saturation is associated with postoperative complications in patients undergoing curative gastrectomy for gastric cancer"],"prefix":"10.1007","volume":"29","author":[{"given":"Chishou","family":"Mitsuura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Ida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Tsubakihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kojiro","family":"Eto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chihiro","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Kosumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuto","family":"Harada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Miyamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0886-4618","authenticated-orcid":false,"given":"Masaaki","family":"Iwatsuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,29]]},"reference":[{"issue":"1","key":"1783_CR1","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1186\/s12885-019-6024-3","volume":"19","author":"P Yuan","year":"2019","unstructured":"Yuan P, Wu Z, Li Z, Bu Z, Wu A, Wu X, et al. Impact of postoperative major complications on long-term survival after radical resection of gastric cancer. BMC Cancer. 2019;19(1):833. https:\/\/doi.org\/10.1186\/s12885-019-6024-3.","journal-title":"BMC Cancer"},{"issue":"1","key":"1783_CR2","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1007\/s10120-020-01102-3","volume":"24","author":"M Tokunaga","year":"2021","unstructured":"Tokunaga M, Kurokawa Y, Machida R, Sato Y, Takiguchi S, Doki Y, et al. Impact of postoperative complications on survival outcomes in patients with gastric cancer: exploratory analysis of a randomized controlled JCOG1001 trial. Gastric Cancer. 2021;24(1):214\u201323. https:\/\/doi.org\/10.1007\/s10120-020-01102-3.","journal-title":"Gastric Cancer"},{"issue":"5","key":"1783_CR3","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.1245\/s10434-012-2720-9","volume":"20","author":"M Tokunaga","year":"2013","unstructured":"Tokunaga M, Tanizawa Y, Bando E, Kawamura T, Terashima M. Poor survival rate in patients with postoperative intra-abdominal infectious complications following curative gastrectomy for gastric cancer. Ann Surg Oncol. 2013;20(5):1575\u201383. https:\/\/doi.org\/10.1245\/s10434-012-2720-9.","journal-title":"Ann Surg Oncol"},{"issue":"2","key":"1783_CR4","doi-asserted-by":"publisher","first-page":"204","DOI":"10.11817\/j.issn.1672-7347.2025.240521","volume":"50","author":"K Xie","year":"2025","unstructured":"Xie K, Feng W, Liu Z, Lei H, Liu H, Tang M. Predictive value of preoperative L3-SMI, AGR, and PNI for overall survival in patients undergoing radical gastrectomy for gastric cancer. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2025;50(2):204\u201314. https:\/\/doi.org\/10.11817\/j.issn.1672-7347.2025.240521.","journal-title":"Zhong Nan Da Xue Xue Bao Yi Xue Ban"},{"issue":"1","key":"1783_CR5","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1038\/s41598-021-04128-4","volume":"12","author":"Q Xiao","year":"2022","unstructured":"Xiao Q, Li X, Duan B, Li X, Liu S, Xu B, et al. Clinical significance of controlling nutritional status score (CONUT) in evaluating outcome of postoperative patients with gastric cancer. Sci Rep. 2022;12(1):93. https:\/\/doi.org\/10.1038\/s41598-021-04128-4.","journal-title":"Sci Rep"},{"issue":"1","key":"1783_CR6","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1186\/s12885-018-4616-y","volume":"18","author":"X Liu","year":"2018","unstructured":"Liu X, Zhang D, Lin E, Chen Y, Li W, Chen Y, et al. Preoperative controlling nutritional status (CONUT) score as a predictor of long-term outcome after curative resection followed by adjuvant chemotherapy in stage II-III gastric Cancer. BMC Cancer. 2018;18(1):699. https:\/\/doi.org\/10.1186\/s12885-018-4616-y.","journal-title":"BMC Cancer"},{"issue":"2","key":"1783_CR7","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1111\/joim.13004","volume":"287","author":"MD Cappellini","year":"2020","unstructured":"Cappellini MD, Musallam KM, Taher AT. Iron deficiency anaemia revisited. J Intern Med. 2020;287(2):153\u201370. https:\/\/doi.org\/10.1111\/joim.13004.","journal-title":"J Intern Med"},{"issue":"2","key":"1783_CR8","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1111\/anae.13773","volume":"72","author":"M Mu\u00f1oz","year":"2017","unstructured":"Mu\u00f1oz M, Acheson AG, Auerbach M, Besser M, Habler O, Kehlet H, et al. International consensus statement on the peri-operative management of anaemia and iron deficiency. Anaesthesia. 2017;72(2):233\u201347. https:\/\/doi.org\/10.1111\/anae.13773.","journal-title":"Anaesthesia"},{"issue":"Suppl 4","key":"1783_CR9","doi-asserted-by":"publisher","first-page":"iv96","DOI":"10.1093\/annonc\/mdx758","volume":"29","author":"M Aapro","year":"2018","unstructured":"Aapro M, Beguin Y, Bokemeyer C, Dicato M, Gasc\u00f3n P, Glaspy J, et al. Management of anaemia and iron deficiency in patients with cancer: ESMO clinical practice guidelines. Ann Oncol. 2018;29(Suppl 4):iv96\u2013110. https:\/\/doi.org\/10.1093\/annonc\/mdx758.","journal-title":"Ann Oncol"},{"issue":"25","key":"1783_CR10","doi-asserted-by":"publisher","first-page":"e218","DOI":"10.1182\/blood-2011-02-337907","volume":"117","author":"TE Galesloot","year":"2011","unstructured":"Galesloot TE, Vermeulen SH, Geurts-Moespot AJ, Klaver SM, Kroot JJ, van Tienoven D, et al. Serum hepcidin: reference ranges and biochemical correlates in the general population. Blood. 2011;117(25):e218\u201325. https:\/\/doi.org\/10.1182\/blood-2011-02-337907.","journal-title":"Blood"},{"key":"1783_CR11","doi-asserted-by":"publisher","unstructured":"Japanese gastric cancer treatment guidelines 2018 (5th edition). Gastric Cancer. 2021;24(1):1\u201321. https:\/\/doi.org\/10.1007\/s10120-020-01042-y","DOI":"10.1007\/s10120-020-01042-y"},{"key":"1783_CR12","unstructured":"WHO Guidelines Approved by the Guidelines Review Committee. WHO guideline on use of ferritin concentrations to assess iron status in individuals and populations. Geneva: World Health Organization \u00a9 World Health Organization 2020.; 2020."},{"issue":"2","key":"1783_CR13","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1097\/SLA.0b013e3181b13ca2","volume":"250","author":"PA Clavien","year":"2009","unstructured":"Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, et al. The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg. 2009;250(2):187\u201396. https:\/\/doi.org\/10.1097\/SLA.0b013e3181b13ca2.","journal-title":"Ann Surg"},{"key":"1783_CR14","doi-asserted-by":"publisher","unstructured":"American Society of Anesthesiologists Statement on ASA Physical Status Classification System. Anesthesiol Open. 2026;1(1):e0002. https:\/\/doi.org\/10.1097\/ao9.0000000000000002.","DOI":"10.1097\/ao9.0000000000000002"},{"key":"1783_CR15","unstructured":"Hendrix JM, Garmon EH. American Society of Anesthesiologists Physical Status Classification System. StatPearls. Treasure Island (FL): StatPearls Publishing Copyright \u00a9 2026. StatPearls Publishing LLC; 2026."},{"issue":"2","key":"1783_CR16","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1254\/jjp.40.342","volume":"40","author":"K Kamikubo","year":"1986","unstructured":"Kamikubo K, Murase H, Murayama M, Miura K. Microcomputer-based nonlinear regression analysis of ligand-binding data: application of Akaike\u2019s information criterion. Jpn J Pharmacol. 1986;40(2):342\u20136. https:\/\/doi.org\/10.1254\/jjp.40.342.","journal-title":"Jpn J Pharmacol"},{"issue":"3","key":"1783_CR17","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.2307\/2533006","volume":"51","author":"CM Hurvich","year":"1995","unstructured":"Hurvich CM, Tsai CL. Model selection for extended quasi-likelihood models in small samples. Biometrics. 1995;51(3):1077\u201384.","journal-title":"Biometrics"},{"issue":"Suppl 1","key":"1783_CR18","doi-asserted-by":"publisher","first-page":"S41","DOI":"10.1089\/sur.2005.6.s1-41","volume":"6","author":"FM Pieracci","year":"2005","unstructured":"Pieracci FM, Barie PS. Iron and the risk of infection. Surg Infect (Larchmt). 2005;6(Suppl 1):S41\u20136. https:\/\/doi.org\/10.1089\/sur.2005.6.s1-41.","journal-title":"Surg Infect (Larchmt)"},{"issue":"6","key":"1783_CR19","first-page":"640","volume":"24","author":"M Mu\u00f1oz","year":"2009","unstructured":"Mu\u00f1oz M, Botella-Romero F, G\u00f3mez-Ram\u00edrez S, Campos A, Garc\u00eda-Erce JA. Iron deficiency and anaemia in bariatric surgical patients: causes, diagnosis and proper management. Nutr Hosp. 2009;24(6):640\u201354.","journal-title":"Nutr Hosp"},{"issue":"13","key":"1783_CR20","doi-asserted-by":"publisher","first-page":"1832","DOI":"10.1002\/bjs.11812","volume":"107","author":"BD Stephensen","year":"2020","unstructured":"Stephensen BD, Reid F, Shaikh S, Carroll R, Smith SR, Pockney P. C-reactive protein trajectory to predict colorectal anastomotic leak: PREDICT study. Br J Surg. 2020;107(13):1832\u20137. https:\/\/doi.org\/10.1002\/bjs.11812.","journal-title":"Br J Surg"},{"issue":"9","key":"1783_CR21","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1172\/jci20945","volume":"113","author":"E Nemeth","year":"2004","unstructured":"Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004;113(9):1271\u20136. https:\/\/doi.org\/10.1172\/jci20945.","journal-title":"J Clin Invest"},{"issue":"Suppl 1","key":"1783_CR22","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.2215\/cjn.01490506","volume":"1","author":"JB Wish","year":"2006","unstructured":"Wish JB. Assessing iron status: beyond serum ferritin and transferrin saturation. Clin J Am Soc Nephrol. 2006;1(Suppl 1):S4\u20138. https:\/\/doi.org\/10.2215\/cjn.01490506.","journal-title":"Clin J Am Soc Nephrol"},{"issue":"7","key":"1783_CR23","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1093\/clinchem\/48.7.1066","volume":"48","author":"C Thomas","year":"2002","unstructured":"Thomas C, Thomas L. Biochemical markers and hematologic indices in the diagnosis of functional iron deficiency. Clin Chem. 2002;48(7):1066\u201376.","journal-title":"Clin Chem"},{"issue":"5","key":"1783_CR24","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1002\/ijc.30797","volume":"141","author":"P Jakszyn","year":"2017","unstructured":"Jakszyn P, Fonseca-Nunes A, Lujan-Barroso L, Aranda N, Tous M, Arija V, et al. Hepcidin levels and gastric cancer risk in the EPIC-EurGast study. Int J Cancer. 2017;141(5):945\u201351. https:\/\/doi.org\/10.1002\/ijc.30797.","journal-title":"Int J Cancer"},{"issue":"4","key":"1783_CR25","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1007\/s11695-024-07081-z","volume":"34","author":"MPS Mu\u00f1oz","year":"2024","unstructured":"Mu\u00f1oz MPS, Ramirez ZPB, Rodriguez ELM, Bland\u00f3n JDR, Agui\u00f1aga SA, Orozco CAO, et al. Transferrin saturation, serum ferritin, and c-reactive protein vs. serum ferritin for an optimal iron deficiency diagnosis in candidates for bariatric surgery. Obes Surg. 2024;34(4):1174\u201384. https:\/\/doi.org\/10.1007\/s11695-024-07081-z.","journal-title":"Obes Surg"},{"issue":"8","key":"1783_CR26","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1038\/nri3863","volume":"15","author":"T Ganz","year":"2015","unstructured":"Ganz T, Nemeth E. Iron homeostasis in host defence and inflammation. Nat Rev Immunol. 2015;15(8):500\u201310. https:\/\/doi.org\/10.1038\/nri3863.","journal-title":"Nat Rev Immunol"},{"issue":"10","key":"1783_CR27","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1056\/NEJMra041809","volume":"352","author":"G Weiss","year":"2005","unstructured":"Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med. 2005;352(10):1011\u201323. https:\/\/doi.org\/10.1056\/NEJMra041809.","journal-title":"N Engl J Med"}],"container-title":["Gastric Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10120-026-01783-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10120-026-01783-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10120-026-01783-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T05:53:52Z","timestamp":1787896432000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10120-026-01783-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,29]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["1783"],"URL":"https:\/\/doi.org\/10.1007\/s10120-026-01783-2","relation":{},"ISSN":["1436-3291","1436-3305"],"issn-type":[{"value":"1436-3291","type":"print"},{"value":"1436-3305","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,29]]},"assertion":[{"value":"7 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no conflict of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions. This study was approved by the Institutional Review Board of Kumamoto University (Approval No. 1037). The opportunity to opt-out was provided on the institutional website.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}}]}}