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Abietic acid (\n                    <jats:bold>2<\/jats:bold>\n                    ), a diterpene having two endocyclic C-C double-bounds (\u0394\n                    <jats:sup>7(8)<\/jats:sup>\n                    and \u0394\n                    <jats:sup>13(14)<\/jats:sup>\n                    ) was used to challenge this putative regioselectivity. The fungus oxidized one of the methyl groups at C-13 in a similar way shown by diterpene\n                    <jats:bold>1<\/jats:bold>\n                    , producing 16-hydroxyabietic acid (\n                    <jats:bold>2a<\/jats:bold>\n                    ). The\n                    <jats:italic>tblastn<\/jats:italic>\n                    analyses of whole-genome contigs indicated that\n                    <jats:italic>A. sclerotiorum<\/jats:italic>\n                    contains an enzyme similar to CYP105A1 from\n                    <jats:italic>Streptomyces griseolus<\/jats:italic>\n                    . The\n                    <jats:italic>ent<\/jats:italic>\n                    -pimaric acid (\n                    <jats:bold>1<\/jats:bold>\n                    ) and its derived products\n                    <jats:bold>1a<\/jats:bold>\n                    -\n                    <jats:bold>1d<\/jats:bold>\n                    were tested for antiparasitic activities against\n                    <jats:italic>Leishmania amazonensis<\/jats:italic>\n                    and\n                    <jats:italic>Trypanozoma cruzi<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1007\/s10123-026-00895-0","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T09:12:04Z","timestamp":1790068324000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Epoxidation of ent-pimara-8(14),15-dien-19-oic acid by whole cells of the endophytic fungus Aspergillus sclerotiorum"],"prefix":"10.1007","author":[{"given":"Zia Ud","family":"Din","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00edvia S.","family":"de Medeiros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. 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