{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T15:39:57Z","timestamp":1784993997937,"version":"3.55.0"},"reference-count":61,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mar Biotechnol"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1007\/s10126-023-10196-6","type":"journal-article","created":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T07:03:18Z","timestamp":1673420598000},"page":"223-234","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Unveiling the Role of Dynamic Alternative Splicing Modulation After Infestation with Sea Lice (Caligus rogercresseyi) in Atlantic Salmon"],"prefix":"10.1007","volume":"25","author":[{"given":"Scarleth","family":"Bravo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Leiva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Moya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osiel","family":"Guzman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Vidal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,1,11]]},"reference":[{"key":"10196_CR1","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1373\/clinchem.2008.112797","volume":"55","author":"SA Bustin","year":"2009","unstructured":"Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley GL, Vandesompele J, Wittwer CT (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 55:611\u2013622","journal-title":"Clin Chem"},{"key":"10196_CR2","doi-asserted-by":"crossref","unstructured":"Chang MX, Zhang J (2017) Alternative pre-mRNA splicing in mammals and teleost fish: a effective strategy for the regulation of immune responses against pathogen infection. Int J Mol Sci 18:1530","DOI":"10.3390\/ijms18071530"},{"key":"10196_CR3","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1016\/j.jmb.2019.03.001","volume":"431","author":"K Chauhan","year":"2019","unstructured":"Chauhan K, Kalam H, Dutt R, Kumar D (2019) RNA Splicing: a new paradigm in host-pathogen interactions. J Mol Biol 431:1565\u20131575","journal-title":"J Mol Biol"},{"key":"10196_CR4","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1007\/s10695-013-9894-3","volume":"40","author":"C Cofre","year":"2014","unstructured":"Cofre C, Gonzalez R, Moya J, Vidal R (2014) Phenotype gene expression differences between resistant and susceptible salmon families to IPNV. Fish Physiol Biochem 40:887\u2013896","journal-title":"Fish Physiol Biochem"},{"key":"10196_CR5","doi-asserted-by":"publisher","first-page":"89","DOI":"10.3354\/dao035089","volume":"35","author":"LH Dawson","year":"1999","unstructured":"Dawson LH, Pike AW, Houlihan DF, McVicar AH (1999) Changes in physiological parameters and feeding behaviour of Atlantic salmon Salmo salar infected with sea lice Lepeophtheirus salmonis. Dis Aquat Organ 35:89\u201399","journal-title":"Dis Aquat Organ"},{"key":"10196_CR6","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.3389\/fimmu.2018.01094","volume":"9","author":"MD D\u00edaz-Mu\u00f1oz","year":"2018","unstructured":"D\u00edaz-Mu\u00f1oz MD, Turner M (2018) Uncovering the role of RNA-binding proteins in gene expression in the immune system. Front Immunol 9:1094","journal-title":"Front Immunol"},{"key":"10196_CR7","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","volume":"29","author":"A Dobin","year":"2013","unstructured":"Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P, Chaisson M, Gingeras TR (2013) STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29:15\u201321","journal-title":"Bioinformatics"},{"key":"10196_CR8","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3354\/dao052057","volume":"52","author":"MD Fast","year":"2002","unstructured":"Fast MD, Ross NW, Mustafa A, Sims DE, Johnson SC, Conboy GA, Speare DJ, Johnson G, Burka JF (2002) Susceptibility of rainbow trout Oncorhynchus mykiss, Atlantic salmon Salmo salar and coho salmon Oncorhynchus kisutch to experimental infection with sea lice Lepeophtheirus salmonis. Dis Aquat Organ 52:57\u201368","journal-title":"Dis Aquat Organ"},{"key":"10196_CR9","doi-asserted-by":"crossref","unstructured":"Froussios K, Mour\u00e3o K, Simpson G, Barton G, Schurch N (2019) Relative abundance of transcripts (RATS): identifying differential isoform abundance from RNA-seq. F1000Res 8:213","DOI":"10.12688\/f1000research.17916.1"},{"key":"10196_CR10","doi-asserted-by":"publisher","first-page":"1815","DOI":"10.1038\/s41598-020-80168-6","volume":"11","author":"W Gan","year":"2021","unstructured":"Gan W, Chung-Davidson YW, Chen Z, Song S, Cui W, He W, Zhang Q, Li W, Li M, Ren J (2021) Global tissue transcriptomic analysis to improve genome annotation and unravel skin pigmentation in goldfish. Sci Rep 11:1815","journal-title":"Sci Rep"},{"key":"10196_CR11","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.vetimm.2005.07.022","volume":"109","author":"A Gruden-Movsesijan","year":"2006","unstructured":"Gruden-Movsesijan A, LjS M (2006) The involvement of the macrophage mannose receptor in the innate immune response to infection with parasite Trichinella spiralis. Vet Immunol Immunopathol 109:57\u201367","journal-title":"Vet Immunol Immunopathol"},{"key":"10196_CR12","doi-asserted-by":"crossref","unstructured":"Guragain P, Tkachov M, B\u00e5tnes AS, Olsen Y, Winge P, Bones AM (2021) Principles and methods of counteracting harmful salmon\u2013arthropod interactions in salmon farming: addressing possibilities, limitations, and future options. Front Mar Sci 8:701793","DOI":"10.3389\/fmars.2021.701793"},{"key":"10196_CR13","doi-asserted-by":"crossref","unstructured":"Hemmingsen W, MacKenzie K, Sagerup K, Remen M, Bloch-Hansen K, Dagbjartarson Imsland AK (2020)\u00a0Caligus elongatus and other\u00a0sea lice of the genus Caligus as parasites of farmed salmonids: a review. Aquaculture 522:73516","DOI":"10.1016\/j.aquaculture.2020.735160"},{"key":"10196_CR14","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1016\/j.bbalip.2014.12.006","volume":"1851","author":"PT Hawkins","year":"2015","unstructured":"Hawkins PT, Stephens LR (2015) PI3K signalling in inflammation. Biochim Biophys Acta 1851:882\u2013897","journal-title":"Biochim Biophys Acta"},{"key":"10196_CR15","doi-asserted-by":"crossref","unstructured":"Jolles JW, Mazu\u00e9 G, Davidson J, Behrmann-Godel J, Couzin ID (2020) Schistocephalus parasite infection alters sticklebacks\u2019 movement ability and thereby shapes social interactions. Sci Rep 10:12282","DOI":"10.1038\/s41598-020-69057-0"},{"key":"10196_CR16","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1038\/nature09782","volume":"469","author":"B Levine","year":"2011","unstructured":"Levine B, Mizushima N, Virgin H (2011) Autophagy in immunity and inflammation. Nature 469:323\u2013335","journal-title":"Nature"},{"key":"10196_CR17","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1186\/1471-2105-12-323","volume":"12","author":"B Li","year":"2011","unstructured":"Li B, Deweys CN (2011) RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics 12:323","journal-title":"BMC Bioinformatics"},{"key":"10196_CR18","doi-asserted-by":"publisher","first-page":"244","DOI":"10.3389\/fgene.2020.00244","volume":"11","author":"BJ Li","year":"2020","unstructured":"Li BJ, Zhu ZX, Qin H, Meng ZN, Lin HR, Xia JH (2020a) Genome-wide characterization of alternative splicing events and their responses to cold stress in tilapia. Front Genet 11:244","journal-title":"Front Genet"},{"key":"10196_CR19","doi-asserted-by":"publisher","first-page":"3154","DOI":"10.3389\/fimmu.2019.03154","volume":"10","author":"A Li","year":"2020","unstructured":"Li A, Song NJ, Riesenberg BP, Li Z (2020b) The emerging roles of endoplasmic reticulum stress in balancing immunity and tolerance in health and diseases: mechanisms and opportunities. Front Immunol 10:3154","journal-title":"Front Immunol"},{"key":"10196_CR20","doi-asserted-by":"publisher","first-page":"497","DOI":"10.3390\/genes13030497","volume":"13","author":"H Li","year":"2022","unstructured":"Li H, Huang J, Zhang J, Gao Y, Han B, Sun D (2022) Identification of alternative splicing events associated with paratuberculosis in dairy cattle using multi-tissue RNA sequencing data. Genes (Basel) 13:497","journal-title":"Genes (basel)"},{"key":"10196_CR21","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1007\/s00438-010-0538-3","volume":"283","author":"J Lu","year":"2010","unstructured":"Lu J, Peatman E, Wang W, Yang Q, Abernathy J, Wang S, Kucuktas H, Liu Z (2010) Alternative splicing in teleost fish genomes: same-species and cross-species analysis and comparisons. Mol Genet Genomics 283:531\u2013539","journal-title":"Mol Genet Genomics"},{"key":"10196_CR22","doi-asserted-by":"publisher","first-page":"401","DOI":"10.3390\/genes13030401","volume":"13","author":"Q Liu","year":"2022","unstructured":"Liu Q, Fang L, Wu C (2022) Alternative splicing and isoforms: from mechanisms to diseases. Genes (Basel) 13:401","journal-title":"Genes (basel)"},{"key":"10196_CR23","doi-asserted-by":"publisher","first-page":"2052","DOI":"10.1093\/bib\/bbz126","volume":"21","author":"A Mehmood","year":"2020","unstructured":"Mehmood A, Laiho A, Ven\u00e4l\u00e4inen MS, McGlinchey AJ, Wang N, Elo LL (2020) Systematic evaluation of differential splicing tools for RNA-seq studies. Brief Bioinform 21:2052\u20132065","journal-title":"Brief Bioinform"},{"key":"10196_CR24","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1186\/s12859-021-04263-9","volume":"22","author":"IB Muller","year":"2021","unstructured":"Muller IB, Meijers S, Kampstra P, van Dijk S, van Elswijk M, Lin M, Wojtuszkiewicz AM, Jansen G, de Jonge R, Cloos J (2021) Computational comparison of common event-based differential splicing tools: practical considerations for laboratory researchers. BMC Bioinformatics 22:347","journal-title":"BMC Bioinformatics"},{"key":"10196_CR25","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1146\/annurev-immunol-032712-095946","volume":"31","author":"K Okkenhaug","year":"2013","unstructured":"Okkenhaug K (2013) Signaling by the phosphoinositide 3-kinase family in immune cells. Annu Rev Immunol 31:675\u2013704","journal-title":"Annu Rev Immunol"},{"key":"10196_CR26","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.physbeh.2014.04.031","volume":"132","author":"\u00d8 \u00d8verli","year":"2014","unstructured":"\u00d8verli \u00d8, Nordgreen J, Mejdell CM, Janczak AM, Kittilsen S, Johansen IB, Horsberg TE (2014) Ectoparasitic sea lice (Lepeophtheirus salmonis) affect behavior and brain serotonergic activity in Atlantic salmon (Salmo salar L.): perspectives on animal welfare. Physiol Behav 132:44\u201350","journal-title":"Physiol Behav"},{"key":"10196_CR27","doi-asserted-by":"crossref","unstructured":"Palzer KA, Bolduan V, K\u00e4fer R, Kleinert H, Bros M, Pautz A (2022) The role of KH-type splicing regulatory protein (KSRP) for Immune functions and tumorigenesis. Cells 11:1482","DOI":"10.3390\/cells11091482"},{"key":"10196_CR28","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s13062-019-0231-3","volume":"14","author":"L Patthy","year":"2019","unstructured":"Patthy L (2019) Exon skipping-rich transcriptomes of animals reflect the significance of exon-shuffling in metazoan proteome evolution. Biol Direct 14:2","journal-title":"Biol Direct"},{"key":"10196_CR29","doi-asserted-by":"crossref","unstructured":"Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29:e45","DOI":"10.1093\/nar\/29.9.e45"},{"key":"10196_CR30","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/s0169-4758(98)01357-x","volume":"15","author":"R Poulin","year":"1999","unstructured":"Poulin R, Thomas F (1999) Phenotypic variability induced by parasites: parasitol. Today 15:28\u201332","journal-title":"Today"},{"key":"10196_CR31","doi-asserted-by":"publisher","first-page":"287","DOI":"10.3389\/fgene.2018.00287","volume":"9","author":"D Robledo","year":"2018","unstructured":"Robledo D, Guti\u00e9rrez AP, Barr\u00eda A, Y\u00e1\u00f1ez JM, Houston RD (2018) Gene expression response to sea lice in Atlantic salmon skin: RNA sequencing comparison between resistant and susceptible animals. Front Genet 9:287","journal-title":"Front Genet"},{"key":"10196_CR32","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1089\/jir.2018.29010.rsa","volume":"38","author":"R Savan","year":"2018","unstructured":"Savan R (2018) Alternative splicing in innate antiviral immunity. J Interferon Cytokine Res 38:317\u2013318","journal-title":"J Interferon Cytokine Res"},{"key":"10196_CR33","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1093\/intimm\/dxx026","volume":"29","author":"A Schaub","year":"2017","unstructured":"Schaub A, Glasmacher E (2017) Splicing in immune cells-mechanistic insights and emerging topics. Int Immunol 29:173\u2013181","journal-title":"Int Immunol"},{"key":"10196_CR34","doi-asserted-by":"publisher","first-page":"E5593","DOI":"10.1073\/pnas.1419161111","volume":"111","author":"S Shen","year":"2014","unstructured":"Shen S, Park JW, Lu ZX, Lin L, Henry MD, Wu YN, Zhou Q, Xing Y (2014) rMATS: robust and flexible detection of differential alternative splicing from replicate RNA-Seq data. Proc Natl Acad Sci U S A 111:E5593\u2013E5601","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10196_CR35","doi-asserted-by":"crossref","unstructured":"Soneson C, Love MI, Robinson MD (2015) Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences. F1000Res 4:1521","DOI":"10.12688\/f1000research.7563.1"},{"key":"10196_CR36","doi-asserted-by":"publisher","first-page":"574","DOI":"10.3390\/genes12040574","volume":"12","author":"Z Su","year":"2021","unstructured":"Su Z, Huang D (2021) Alternative splicing of pre-mrna in the control of immune activity. Genes 12:574","journal-title":"Genes"},{"key":"10196_CR37","doi-asserted-by":"crossref","unstructured":"Sutherland BJ, Koczka KW, Yasuike M, Jantzen SG, Yazawa R, Koop BF, Jones SR (2014) Comparative transcriptomics of Atlantic Salmo salar, chum Oncorhynchus keta and pink salmon O. gorbuscha during infections with salmon lice Lepeophtheirus salmonis. BMC Genomics 15:200","DOI":"10.1186\/1471-2164-15-200"},{"key":"10196_CR38","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1139\/facets-2017-002","volume":"2","author":"BJG Sutherland","year":"2017","unstructured":"Sutherland BJG, Covello JM, Friend SE, Poley JD, Koczka KW, Purcell SL, MacLeod TL, Donovan BR, Pino J, Gonz\u00e1lez-Vecino JL, Gonzalez J, Troncoso J, Koop BF, Wadsworth SL, Fast MD (2017) Host-parasite transcriptomics during immunostimulant-enhanced rejection of salmon lice (Lepeophtheirus salmonis) by Atlantic salmon (Salmo salar). FACETS 2:477\u2013495","journal-title":"FACETS"},{"key":"10196_CR39","doi-asserted-by":"publisher","first-page":"91","DOI":"10.3354\/meps12746","volume":"606","author":"R Susdorf","year":"2018","unstructured":"Susdorf R, Salama NKG, Todd CD, Hillman RJ, Elsmere P, Lusseau D (2018) Context-dependent reduction in somatic condition of wild Atlantic salmon infested with sea lice. Mar Ecol Prog Ser 606:91\u2013104","journal-title":"Mar Ecol Prog Ser"},{"key":"10196_CR41","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1186\/1471-2164-12-141","volume":"12","author":"TM Tadiso","year":"2011","unstructured":"Tadiso TM, Krasnov A, Skugor S, Afanasyev S, Hordvik I, Nilsen F (2011) Gene expression analyses of immune responses in Atlantic salmon during early stages of infection by salmon louse (Lepeophtheirus salmonis) revealed bi-phasic responses coinciding with the copepod-chalimus transition. BMC Genomics 12:141","journal-title":"BMC Genomics"},{"key":"10196_CR42","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1007\/s10126-018-9844-2","volume":"20","author":"S Tan","year":"2018","unstructured":"Tan S, Wang W, Zhong X, Tian C, Niu D, Bao L, Zhou T, Jin Y, Yang Y, Yuan Z, Gao D, Dunham R, Liu Z (2018) Increased alternative splicing as a host response to Edwardsiella ictaluri infection in catfish. Mar Biotechnol 20:729\u2013738","journal-title":"Mar Biotechnol"},{"key":"10196_CR43","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.fsi.2019.05.008","volume":"91","author":"S Tan","year":"2019","unstructured":"Tan S, Wang W, Tian C, Niu D, Zhou T, Yang Y, Gao D, Liu Z (2019) Post-transcriptional regulation through alternative splicing after infection with Flavobacterium columnare in channel catfish (Ictalurus punctatus). Fish Shellfish Immunol 91:188\u2013193","journal-title":"Fish Shellfish Immunol"},{"key":"10196_CR44","doi-asserted-by":"publisher","first-page":"1759","DOI":"10.1101\/gr.220962.117","volume":"27","author":"J Tapial","year":"2017","unstructured":"Tapial J, Ha K, Sterne-Weiler T, Gohr A, Braunschweig U, Hermoso-Pulido A, Quesnel-Valli\u00e8res M, Permanyer J, Sodaei R, Marquez Y, Cozzuto L, Wang X, G\u00f3mez-Vel\u00e1zquez M, Rayon T, Manzanares M, Ponomarenko J, Blencowe BJ, Irimia M (2017) An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms. Genome Res 27:1759\u20131768","journal-title":"Genome Res"},{"key":"10196_CR45","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/s13059-020-01967-8","volume":"21","author":"S Tiberi","year":"2020","unstructured":"Tiberi S, Robinson MD (2020) BANDITS: Bayesian differential splicing accounting for sample-to-sample variability and mapping uncertainty. Genome Biol 21:69","journal-title":"Genome Biol"},{"key":"10196_CR46","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.gpb.2014.04.001","volume":"12","author":"C Tokheim","year":"2014","unstructured":"Tokheim C, Park JW, Xing Y (2014) PrimerSeq: design and visualization of RT-PCR primers for alternative splicing using RNA-seq data. Genom Proteom Bioinform\u00a012:105\u2013109","journal-title":"Genomics Proteomics Bioinformatics"},{"key":"10196_CR47","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s12711-016-0226-9","volume":"48","author":"HY Tsai","year":"2016","unstructured":"Tsai HY, Hamilton A, Tinch AE, Guy DR, Bron JE, Taggart JB, Gharbi K, Stear M, Matika O, Pong-Wong R, Bishop SC, Houston RD (2016) Genomic prediction of host resistance to sea lice in farmed Atlantic salmon populations. Genet Sel Evol 48:47","journal-title":"Genet Sel Evol"},{"key":"10196_CR48","doi-asserted-by":"publisher","first-page":"3246","DOI":"10.1111\/j.1742-4658.2011.08274.x","volume":"278","author":"L Twyffels","year":"2011","unstructured":"Twyffels L, Gueydan T, Kruys V (2011) Shuttling SR proteins: more than splicing factors. FEBS 278:3246\u20133255","journal-title":"FEBS"},{"key":"10196_CR49","doi-asserted-by":"publisher","first-page":"2417","DOI":"10.3390\/ijms21072417","volume":"21","author":"N Umasuthan","year":"2021","unstructured":"Umasuthan N, Xue X, Caballero-Solares A, Kumar S, Westcott JD, Chen Z, Fast MD, Skugor S, Nowak BF, Taylor RG, Rise ML (2021) Transcriptomic profiling in fins of Atlantic salmon parasitized with sea lice: evidence for an early imbalance between chalimus-induced immunomodulation and the host\u2019s defense response. Int J Mol Sci 21:2417","journal-title":"Int J Mol Sci"},{"key":"10196_CR50","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1016\/j.scitotenv.2018.08.334","volume":"649","author":"MA Urbina","year":"2019","unstructured":"Urbina MA, Cumillaf JP, Paschke K, Gebauer P (2019) Effects of pharmaceuticals used to treat salmon lice on non-target species: evidence from a systematic review. Sci Total Environ 649:1124\u20131136","journal-title":"Sci Total Environ"},{"key":"10196_CR51","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.3389\/fimmu.2017.01677","volume":"8","author":"I van Die","year":"2017","unstructured":"van Die I, Cummings RD (2017) The mannose receptor in regulation of helminth-mediated host immunity. Front Immunol 8:1677","journal-title":"Front Immunol"},{"key":"10196_CR52","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.pt.2007.12.010","volume":"24","author":"GN Wagner","year":"2008","unstructured":"Wagner GN, Fast MD, Johnson SC (2008) Physiology and immunology of Lepeophtheirus salmonis infections of salmonids. Trends Parasitol 24:176\u2013183","journal-title":"Trends Parasitol"},{"key":"10196_CR53","doi-asserted-by":"crossref","unstructured":"Wagner RE, Frye M (2021) Noncanonical functions of the serine-arginine-rich splicing factor (SR) family of proteins in development and disease. Bioessays 43:e2000242","DOI":"10.1002\/bies.202000242"},{"key":"10196_CR54","doi-asserted-by":"publisher","first-page":"152","DOI":"10.3892\/br.2014.407","volume":"3","author":"Y Wang","year":"2015","unstructured":"Wang Y, Liu J, Huang BO, Xu YM, Li J, Huang LF, Lin J, Zhang J, Min QH, Yang WM, Wang XZ (2015) Mechanism of alternative splicing and its regulation (review). Biomed Rep 3:152\u2013158","journal-title":"Biomed Rep"},{"key":"10196_CR55","doi-asserted-by":"crossref","unstructured":"Wang XG, Ju ZH, Hou MH, Jiang Q, Yang CH, Zhang Y, Sun Y, Li RL, Wang CF, Zhong JF, Huang JM (2016) Deciphering transcriptome and complex alternative splicing transcripts in mammary gland tissues from cows naturally infected with Staphylococcus aureus mastitis. PLoS ONE 11:e0159719","DOI":"10.1371\/journal.pone.0159719"},{"key":"10196_CR56","doi-asserted-by":"publisher","first-page":"1594","DOI":"10.1016\/j.celrep.2019.09.078","volume":"29","author":"KO West","year":"2019","unstructured":"West KO, Scott HM, Torres-Odio S, West AP, Patrick KL, Watson RO (2019) The splicing factor hnRNP M is a critical regulator of innate immune gene expression in macrophages. Cell Rep 29:1594\u20131609","journal-title":"Cell Rep"},{"key":"10196_CR57","doi-asserted-by":"publisher","first-page":"64","DOI":"10.3109\/08916930903374634","volume":"43","author":"DC Wickramarachchi","year":"2010","unstructured":"Wickramarachchi DC, Theofilopoulos AN, Dwight HK (2010) Immune pathology associated with altered actin cytoskeleton regulation. Autoimmunity 43:64\u201375","journal-title":"Autoimmunity"},{"key":"10196_CR58","doi-asserted-by":"crossref","unstructured":"Wu T, Hu E, Xu S, Chen M, Guo P, Dai Z, Feng T, Zhou L, Tang W, Zhan L, Fu X, Liu S, Bo X, Yu G (2021) ClusterProfiler 4.0: A universal enrichment tool for interpreting omics data. Innovation (Camb) 2:100141","DOI":"10.1016\/j.xinn.2021.100141"},{"key":"10196_CR59","doi-asserted-by":"publisher","first-page":"3","DOI":"10.3390\/ijms17010003","volume":"17","author":"M Yabas","year":"2015","unstructured":"Yabas M, Elliott H, Hoyne GF (2015) The role of alternative splicing in the control of immune homeostasis and cellular differentiation. Int J Mol Sci 17:3","journal-title":"Int J Mol Sci"},{"key":"10196_CR60","doi-asserted-by":"publisher","first-page":"10424","DOI":"10.3390\/ijms150610424","volume":"15","author":"S Yang","year":"2014","unstructured":"Yang S, Tang F, Zhu H (2014) Alternative splicing in plant immunity. Int J Mol Sci 15:0424\u201310445","journal-title":"Int J Mol Sci"},{"key":"10196_CR62","doi-asserted-by":"publisher","first-page":"1577","DOI":"10.1104\/pp.107.108720","volume":"145","author":"XC Zhang","year":"2017","unstructured":"Zhang XC, Gassmann W (2017) Alternative splicing and mRNA levels of the disease resistance gene RPS4 are induced during defense responses. Plant Physiol 145:1577\u20131557","journal-title":"Plant Physiol"},{"key":"10196_CR63","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.fsi.2019.04.196","volume":"91","author":"R Zindrili","year":"2019","unstructured":"Zindrili R, Krol E, Mente E, Douglas A, Martin SAM (2019) Impact of sea lice (Caligus rogercresseyi) infection levels on skin transcriptome in Atlantic salmon (Salmo salar). Fish Shellfish Immunol 91:436\u2013437","journal-title":"Fish Shellfish Immunol"}],"container-title":["Marine Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10126-023-10196-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10126-023-10196-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10126-023-10196-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T09:15:56Z","timestamp":1683278156000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10126-023-10196-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,11]]},"references-count":61,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10196"],"URL":"https:\/\/doi.org\/10.1007\/s10126-023-10196-6","relation":{},"ISSN":["1436-2228","1436-2236"],"issn-type":[{"value":"1436-2228","type":"print"},{"value":"1436-2236","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,11]]},"assertion":[{"value":"9 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 January 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 January 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}