{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T04:24:27Z","timestamp":1743740667991,"version":"3.37.3"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Emerg Radiol"],"DOI":"10.1007\/s10140-024-02229-x","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T07:01:50Z","timestamp":1713164510000},"page":"321-330","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Beyond pulmonary embolism: Alternative diagnosis and incidental findings on CT pulmonary angiography in sickle cell disease"],"prefix":"10.1007","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6485-5460","authenticated-orcid":false,"given":"Ali","family":"Hassan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reem","family":"Maki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahdi","family":"Aljawad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Alzayer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Habeeb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aqeel","family":"Alzaher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adnan","family":"Alawami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatimah","family":"Alaithan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9014-951X","authenticated-orcid":false,"given":"Jalila","family":"Adnan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,15]]},"reference":[{"issue":"8","key":"2229_CR1","doi-asserted-by":"publisher","first-page":"e585","DOI":"10.1016\/S2352-3026(23)00118-7","volume":"10","author":"GBDSCD Collaborators","year":"2023","unstructured":"Collaborators GBDSCD (2023) Global, regional, and national prevalence and mortality burden of sickle cell disease, 2000\u20132021: a systematic analysis from the global burden of Disease Study 2021. Lancet Haematol 10(8):e585\u2013e599","journal-title":"Lancet Haematol"},{"key":"2229_CR2","doi-asserted-by":"publisher","first-page":"101","DOI":"10.2147\/JBM.S291394","volume":"12","author":"UO Ogu","year":"2021","unstructured":"Ogu UO, Badamosi NU, Camacho PE, Freire AX, Adams-Graves P (2021) Management of Sickle Cell Disease complications Beyond Acute chest syndrome. J Blood Med 12:101\u2013114","journal-title":"J Blood Med"},{"issue":"10","key":"2229_CR3","doi-asserted-by":"publisher","first-page":"2380","DOI":"10.3324\/haematol.2019.239343","volume":"105","author":"N Conran","year":"2020","unstructured":"Conran N, De Paula EV (2020) Thromboinflammatory mechanisms in sickle cell disease - challenging the hemostatic balance. Haematologica 105(10):2380\u20132390","journal-title":"Haematologica"},{"issue":"8","key":"2229_CR4","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.2967\/jnumed.117.205641","volume":"59","author":"P Tivnan","year":"2018","unstructured":"Tivnan P, Billett HH, Freeman LM, Haramati LB (2018) Imaging for Pulmonary Embolism in Sickle Cell Disease: a 17-Year experience. J Nucl Med 59(8):1255\u20131259","journal-title":"J Nucl Med"},{"issue":"9","key":"2229_CR5","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1164\/rccm.201105-0783OC","volume":"184","author":"A Mekontso Dessap","year":"2011","unstructured":"Mekontso Dessap A, Deux JF, Abidi N, Lavenu-Bombled C, Melica G, Renaud B, Godeau B, Adnot S, Brochard L, Brun-Buisson C et al (2011) Pulmonary artery thrombosis during acute chest syndrome in sickle cell disease. Am J Respir Crit Care Med 184(9):1022\u20131029","journal-title":"Am J Respir Crit Care Med"},{"issue":"11","key":"2229_CR6","doi-asserted-by":"publisher","first-page":"1436","DOI":"10.5858\/2001-125-1436-PTAIPW","volume":"125","author":"MO Adedeji","year":"2001","unstructured":"Adedeji MO, Cespedes J, Allen K, Subramony C, Hughson MD (2001) Pulmonary thrombotic arteriopathy in patients with sickle cell disease. Arch Pathol Lab Med 125(11):1436\u20131441","journal-title":"Arch Pathol Lab Med"},{"issue":"1","key":"2229_CR7","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1007\/s10140-024-02200-w","volume":"31","author":"JH Chamberlin","year":"2024","unstructured":"Chamberlin JH, Ogbonna A, Abrol S, Maisuria D, Miller E, McGuire A, Knight H, O\u2019Doherty J, Baruah D, Schoepf UJ et al (2024) Enhancing diagnostic precision for acute chest syndrome in sickle cell disease: insights from dual-energy CT lung perfusion mapping. Emerg Radiol 31(1):73\u201382","journal-title":"Emerg Radiol"},{"key":"2229_CR8","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2147\/PLMI.S29393","volume":"4","author":"EE Fakunle","year":"2012","unstructured":"Fakunle EE, Eteng K, Shokunbi WA (2012) DD dimer levels in patients with sickle cell disease during bone pain crises and in the steady state. Pathol Lab Med Int 4:21\u201325","journal-title":"Pathol Lab Med Int"},{"issue":"1","key":"2229_CR9","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/s12245-020-00281-1","volume":"13","author":"O Al Dandan","year":"2020","unstructured":"Al Dandan O, Hassan A, Alnasr A, Al Gadeeb M, AbuAlola H, Alshahwan S, Al Shammari M, Alzaki A (2020) The use of clinical decision rules for pulmonary embolism in the emergency department: a retrospective study. Int J Emerg Med 13(1):23","journal-title":"Int J Emerg Med"},{"issue":"3","key":"2229_CR10","doi-asserted-by":"publisher","first-page":"1901647","DOI":"10.1183\/13993003.01647-2019","volume":"54","author":"SV Konstantinides","year":"2019","unstructured":"Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, Huisman MV, Humbert M, Jennings CS, Jimenez D et al (2019) 2019 ESC guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): the Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC). Eur Respir J 54(3):1901647","journal-title":"Eur Respir J"},{"issue":"1","key":"2229_CR11","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s12245-020-00303-y","volume":"13","author":"O Al Dandan","year":"2020","unstructured":"Al Dandan O, Hassan A, AbuAlola H, Alzaki A, Alwaheed A, Alalwan M, Al Shammari M, AlShamlan N, Alsaif HS (2020) Clinical and imaging profiles of pulmonary embolism: a single-institution experience. Int J Emerg Med 13(1):47","journal-title":"Int J Emerg Med"},{"issue":"5","key":"2229_CR12","doi-asserted-by":"publisher","first-page":"e43","DOI":"10.1111\/bjh.18494","volume":"199","author":"JC Winer","year":"2022","unstructured":"Winer JC, Yee ME, Ataga KI, Lebensburger JD, Zahr RS (2022) Patients with sickle cell disease who develop end-stage kidney disease continue to experience poor survival - A 19-year United States Renal Data System study. Br J Haematol 199(5):e43\u2013e47","journal-title":"Br J Haematol"},{"issue":"6","key":"2229_CR13","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1007\/s10140-017-1541-3","volume":"24","author":"J Jensen","year":"2017","unstructured":"Jensen J, Lin T, Fishman EK, Johnson PT (2017) Pulmonary CTA in sickle cell patients: quantitative assessment of enhancement quality. Emerg Radiol 24(6):667\u2013674","journal-title":"Emerg Radiol"},{"issue":"2","key":"2229_CR14","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1007\/s10140-023-02126-9","volume":"30","author":"A Hassan","year":"2023","unstructured":"Hassan A, Taleb M, Hasan W, Shehab F, Maki R, Alhamar N (2023) Positive rate and quality assessment of CT pulmonary angiography in sickle cell disease: a case\u2013control study. Emerg Radiol 30(2):209\u2013216","journal-title":"Emerg Radiol"},{"key":"2229_CR15","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/j.ajem.2022.01.064","volume":"54","author":"A Eskandari","year":"2022","unstructured":"Eskandari A, Narayanasamy S, Ward C, Priya S, Aggarwal T, Elam J, Nagpal P (2022) Prevalence and significance of incidental findings on computed tomography pulmonary angiograms: a retrospective cohort study. Am J Emerg Med 54:232\u2013237","journal-title":"Am J Emerg Med"},{"issue":"1","key":"2229_CR16","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/s10140-018-1641-8","volume":"26","author":"O Anjum","year":"2019","unstructured":"Anjum O, Bleeker H, Ohle R (2019) Computed tomography for suspected pulmonary embolism results in a large number of non-significant incidental findings and follow-up investigations. Emerg Radiol 26(1):29\u201335","journal-title":"Emerg Radiol"},{"issue":"1","key":"2229_CR17","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1590\/S1806-37562016000000105","volume":"42","author":"EV Ferreira","year":"2016","unstructured":"Ferreira EV, Gazzana MB, Sarmento MB, Guazzelli PA, Hoffmeister MC, Guerra VA, Seligman R, Knorst MM (2016) Alternative diagnoses based on CT angiography of the chest in patients with suspected pulmonary thromboembolism. J Bras Pneumol 42(1):35\u201341","journal-title":"J Bras Pneumol"},{"issue":"5","key":"2229_CR18","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1513\/AnnalsATS.201404-144OC","volume":"12","author":"A Perelas","year":"2015","unstructured":"Perelas A, Dimou A, Saenz A, Rhee JH, Teerapuncharoen K, Rowden A, Eiger G (2015) Incidental findings on computed tomography angiography in patients evaluated for pulmonary embolism. Ann Am Thorac Soc 12(5):689\u2013695","journal-title":"Ann Am Thorac Soc"},{"issue":"6","key":"2229_CR19","doi-asserted-by":"publisher","first-page":"1893","DOI":"10.1378\/chest.13-0157","volume":"144","author":"J van Es","year":"2013","unstructured":"van Es J, Douma RA, Schreuder SM, Middeldorp S, Kamphuisen PW, Gerdes VEA, Beenen LFM (2013) Clinical impact of findings supporting an alternative diagnosis on CT pulmonary angiography in patients with suspected pulmonary embolism. Chest 144(6):1893\u20131899","journal-title":"Chest"},{"issue":"1","key":"2229_CR20","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/1471-2466-13-9","volume":"13","author":"S Chandra","year":"2013","unstructured":"Chandra S, Sarkar PK, Chandra D, Ginsberg NE, Cohen RI (2013) Finding an alternative diagnosis does not justify increased use of CT-pulmonary angiography. BMC Pulm Med 13(1):9","journal-title":"BMC Pulm Med"},{"issue":"1","key":"2229_CR21","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1002\/ajh.21550","volume":"85","author":"SK Ballas","year":"2010","unstructured":"Ballas SK, Lieff S, Benjamin LJ, Dampier CD, Heeney MM, Hoppe C, Johnson CS, Rogers ZR, Smith-Whitley K, Wang WC et al (2010) Definitions of the phenotypic manifestations of sickle cell disease. Am J Hematol 85(1):6\u201313","journal-title":"Am J Hematol"},{"issue":"4","key":"2229_CR22","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1002\/jha2.273","volume":"2","author":"M Seck","year":"2021","unstructured":"Seck M, Ba O, Faye BF, Tour\u00e9 SA, Gu\u00e8ye YB, Dieng N, Sall A, Gadji M, Tour\u00e9 AO, Diop S (2021) Homozygous sickle cell disease related mortality in Senegal (2011\u20132020). eJHaem 2(4):711\u2013715","journal-title":"eJHaem"},{"issue":"3","key":"2229_CR23","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.annemergmed.2022.03.027","volume":"80","author":"CS Evans","year":"2022","unstructured":"Evans CS, Arthur R, Kane M, Omofoye F, Chung AE, Moreton E, Moore C (2022) Incidental radiology findings on computed Tomography studies in Emergency Department patients: a systematic review and Meta-analysis. Ann Emerg Med 80(3):243\u2013256","journal-title":"Ann Emerg Med"},{"issue":"1","key":"2229_CR24","doi-asserted-by":"publisher","first-page":"117","DOI":"10.2214\/AJR.22.28926","volume":"221","author":"MS Davenport","year":"2023","unstructured":"Davenport MS (2023) Incidental findings and low-value care. Am J Roentgenol 221(1):117\u2013123","journal-title":"Am J Roentgenol"},{"issue":"4","key":"2229_CR25","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1016\/j.jemermed.2018.06.001","volume":"55","author":"AL Waterbrook","year":"2018","unstructured":"Waterbrook AL, Manning MA, Dalen JE (2018) The significance of incidental findings on computed tomography of the chest. J Emerg Med 55(4):503\u2013506","journal-title":"J Emerg Med"},{"issue":"9","key":"2229_CR26","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1002\/jgh3.12622","volume":"5","author":"SOO Mohamed","year":"2021","unstructured":"Mohamed SOO, Ibrahim OAO, Mohammad DAA, Ali AHM (2021) Correlates of gallbladder stones among patients with sickle cell disease: a meta-analysis. JGH Open 5(9):997\u20131003","journal-title":"JGH Open"},{"issue":"1","key":"2229_CR27","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.jceh.2020.08.003","volume":"11","author":"DL Praharaj","year":"2021","unstructured":"Praharaj DL, Anand AC (2021) Sickle Hepatopathy. J Clin Exp Hepatol 11(1):82\u201396","journal-title":"J Clin Exp Hepatol"},{"issue":"2","key":"2229_CR28","doi-asserted-by":"publisher","first-page":"204589402110183","DOI":"10.1177\/20458940211018345","volume":"11","author":"JL Simonson","year":"2021","unstructured":"Simonson JL, Pandya D, Kang J, Talwar A, Zaidi GZ (2021) Enlarged pulmonary artery on computed tomography and respiratory failure in sickle cell disease acute chest syndrome. Pulm Circ 11(2):20458940211018345","journal-title":"Pulm Circ"},{"issue":"6","key":"2229_CR29","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1164\/rccm.201401-0065ST","volume":"189","author":"ES Klings","year":"2014","unstructured":"Klings ES, Machado RF, Barst RJ, Morris CR, Mubarak KK, Gordeuk VR, Kato GJ, Ataga KI, Gibbs JS, Castro O et al (2014) An official American Thoracic Society clinical practice guideline: diagnosis, risk stratification, and management of pulmonary hypertension of sickle cell disease. Am J Respir Crit Care Med 189(6):727\u2013740","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Emergency Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10140-024-02229-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10140-024-02229-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10140-024-02229-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T03:59:40Z","timestamp":1716868780000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10140-024-02229-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,15]]},"references-count":29,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,6]]}},"alternative-id":["2229"],"URL":"https:\/\/doi.org\/10.1007\/s10140-024-02229-x","relation":{},"ISSN":["1438-1435"],"issn-type":[{"type":"electronic","value":"1438-1435"}],"subject":[],"published":{"date-parts":[[2024,4,15]]},"assertion":[{"value":"6 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Nothing to Disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}