{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T13:43:26Z","timestamp":1772027006386,"version":"3.50.1"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Funct Integr Genomics"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1007\/s10142-023-01004-4","type":"journal-article","created":{"date-parts":[[2023,3,3]],"date-time":"2023-03-03T14:02:56Z","timestamp":1677852176000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["RETRACTED ARTICLE: Denosumab treatment for progressive Enneking stage II cervical giant-cell tumor conservatively"],"prefix":"10.1007","volume":"23","author":[{"given":"YiXuan","family":"Tan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuhan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinling","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoming","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuhui","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiefeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,3,3]]},"reference":[{"key":"1004_CR1","doi-asserted-by":"publisher","first-page":"1881","DOI":"10.1007\/s00256-021-03752-5","volume":"50","author":"YC Chang","year":"2021","unstructured":"Chang YC, Stoyanova R, Danilova S, Pretell-Mazzini JA, Kerr DA, Wilky BA, Subhawong T (2021) Radiomics on radiography predicts giant cell tumor histologic response to denosumab. Skelet Radiol 50:1881\u20131887. https:\/\/doi.org\/10.1007\/s00256-021-03752-5","journal-title":"Skelet Radiol"},{"issue":"6","key":"1004_CR2","doi-asserted-by":"publisher","first-page":"385","DOI":"10.5414\/NP300970","volume":"35","author":"D Chatterjee","year":"2016","unstructured":"Chatterjee D, Gupta K, Singla N, Kapoor A (2016) Sphenoid bone: a rare site for giant cell tumor \u2013 case report with literature review. Clin Neuropathol 35(6):385. https:\/\/doi.org\/10.5414\/NP300970","journal-title":"Clin Neuropathol"},{"key":"1004_CR3","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1016\/S1470-2045(13)70277-8","volume":"14","author":"S Chawla","year":"2013","unstructured":"Chawla S, Henshaw R, Seeger L, Choy E, Blay JY, Ferrari S, Kroep J, Grimer R, Reichardt P, Rutkowski P, Schuetze S, Skubitz K, Staddon A, Thomas D, Qian Y, Jacobs I (2013) Safety and efcacy of denosumab for adults and skeletally mature adolescents with giant cell tumour of bone: interim analysis of an open-label, parallel-group, phase 2 study. Lancet Oncol 14:901\u2013908","journal-title":"Lancet Oncol"},{"key":"1004_CR4","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1186\/s12957-015-0438-4","volume":"13","author":"G Chen","year":"2015","unstructured":"Chen G, Li J, Li X, Fan H, Guo Z, Wang Z (2015) Giant cell tumor of axial vertebra: surgical experience of fifive cases and a review of the literature. World J Surg Oncol 13:62","journal-title":"World J Surg Oncol"},{"issue":"1","key":"1004_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12891-020-03294-2","volume":"21","author":"X Chen","year":"2020","unstructured":"Chen X, Li H, Zhu S, Wang Y, Qian W (2020) Pre-operative denosumab is associated with higher risk of local recurrence in giant cell tumor of bone: a systematic review and meta-analysis. BMC Musculoskelet Disord 21(1):1\u20139. https:\/\/doi.org\/10.1186\/s12891-020-03294-2","journal-title":"BMC Musculoskelet Disord"},{"key":"1004_CR6","doi-asserted-by":"publisher","first-page":"1576","DOI":"10.1097\/PAS.0000000000000512","volume":"39","author":"AH Cleven","year":"2015","unstructured":"Cleven AH, Hocker S, Briaire-de Bruijn I, Szuhai K, Cleton-Jansen AM, Bovee JV (2015) Mutation analysis of H3F3A and H3F3B as a diagnostic tool for giant cell tumor of bone and chondroblastoma. Am J Surg Pathol 39:1576\u20131583","journal-title":"Am J Surg Pathol"},{"key":"1004_CR7","doi-asserted-by":"publisher","unstructured":"Demura S, Kato S, Yoshioka K, Shinmura K, Yokogawa N (2022) The influence of costal resection on pulmonary function after total en bloc spondylectomy for spine tumor. J Orthop. https:\/\/doi.org\/10.1016\/j.jos.2022.07.015","DOI":"10.1016\/j.jos.2022.07.015"},{"issue":"1","key":"1004_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12891-020-3129-4","volume":"21","author":"P-G Duan","year":"2020","unstructured":"Duan P-G, Sheng Y-H, Deng C-H, Tang B-Y, Yao H-Q (2020) Recurrent giant cell tumour of the thoracic spine managed by total en bloc spondylectomy and denosumab therapy: a case report. BMC Musculoskelet Disord 21(1):1\u20137. https:\/\/doi.org\/10.1186\/s12891-020-3129-4","journal-title":"BMC Musculoskelet Disord"},{"key":"1004_CR9","doi-asserted-by":"publisher","first-page":"526","DOI":"10.3171\/2014.10.SPINE13937","volume":"22","author":"T Goldschlager","year":"2015","unstructured":"Goldschlager T, Dea N, Boyd M, Reynolds J, Patel S, Rhines LD et al (2015) Giant cell tumors of the spine: has denosumab changed the treatment paradigm? J Neurosurg Spine 22:526\u2013533","journal-title":"J Neurosurg Spine"},{"key":"1004_CR10","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1016\/j.spinee.2019.02.011","volume":"19","author":"Q Jia","year":"2019","unstructured":"Jia Q, Chen G, Cao J et al (2019) Clinical features and prognostic factors of pediatric spine giant cell tumors: report of 31 clinical cases in a single center. Spine J 19:1232\u20131241","journal-title":"Spine J"},{"issue":"2","key":"1004_CR11","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1302\/0301-620x.102b2.bjj-2019-0813.r1","volume":"102","author":"CY Lim","year":"2020","unstructured":"Lim CY, Liu X, He F, Liang H, Yang Y, Ji T, Guo W (2020) Retrospective cohort study of 68 sacral giant cell tumours treated with nerve-sparing surgery and evaluation on therapeutic benefits of denosumab therapy. Bone & Joint J 102(2):177\u2013185. https:\/\/doi.org\/10.1302\/0301-620x.102b2.bjj-2019-0813.r1","journal-title":"Bone & Joint J"},{"key":"1004_CR12","doi-asserted-by":"publisher","unstructured":"Li Z, Guo L, Zhang P, Wang J, Wang X (2022) A systematic review of perioperative complications in en bloc resection for spinal tumors . Global Spine J. https:\/\/doi.org\/10.1177\/21925682221120644","DOI":"10.1177\/21925682221120644"},{"key":"1004_CR13","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1186\/s12891-020-3053-7","volume":"21","author":"Y Meng","year":"2020","unstructured":"Meng Y, Ma J, Shu L, Zhou X et al (2020) Modified C7 pedicle subtraction osteotomy for the correction of cervicothoracic kyphosis. BMC Musculoskelet Disord 21:28. https:\/\/doi.org\/10.1186\/s12891-020-3053-7","journal-title":"BMC Musculoskelet Disord"},{"issue":"1","key":"1004_CR14","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1302\/0301-620x.103b1.bjj-2020-0274.r1","volume":"103","author":"DL Perrin","year":"2021","unstructured":"Perrin DL, Visgauss JD, Wilson DA, Griffin AM, Abdul Razak AR (2021) The role of Denosumab in joint preservation for patients with giant cell tumour of bone. Bone & Joint J 103(1):184\u2013191. https:\/\/doi.org\/10.1302\/0301-620x.103b1.bjj-2020-0274.r1","journal-title":"Bone & Joint J"},{"issue":"6","key":"1004_CR15","doi-asserted-by":"publisher","first-page":"326","DOI":"10.3928\/01477447-20211001-09","volume":"44","author":"S Tsukamoto","year":"2021","unstructured":"Tsukamoto S, Mavrogenis AF, Tanaka Y, Kido A, Kawaguchi M, Errani C (2021) Denosumab does not decrease local recurrence in giant cell tumor of bone treated with en bloc resection. Orthopedics 44(6):326\u2013332. https:\/\/doi.org\/10.3928\/01477447-20211001-09","journal-title":"Orthopedics"},{"key":"1004_CR16","doi-asserted-by":"publisher","first-page":"100410","DOI":"10.1016\/j.jbo.2021.100410","volume":"32","author":"Y Yang","year":"2021","unstructured":"Yang Y, Xu H, Liu W, Niu X (2021a) Study of imaging changes following preoperative denosumab for giant cell tumor of bone. J Bone Oncol 32:100410. https:\/\/doi.org\/10.1016\/j.jbo.2021.100410","journal-title":"J Bone Oncol"},{"key":"1004_CR17","doi-asserted-by":"publisher","unstructured":"Yang Y, Xu H, Liu W (2021b) Study of imaging changes following preoperative denosumab for giant cell tumor of bone. J Bone Oncol. https:\/\/doi.org\/10.1016\/j.jbo.2021.100410","DOI":"10.1016\/j.jbo.2021.100410"},{"key":"1004_CR18","doi-asserted-by":"publisher","first-page":"100441","DOI":"10.1016\/j.jbo.2022.100441","volume":"35","author":"J Yue","year":"2022","unstructured":"Yue J, Sun W, Li S (2022) Denosumab versus zoledronic acid in cases of surgically unsalvageable giant cell tumor of bone: a randomized clinical trial. J Bone Oncol 35:100441. https:\/\/doi.org\/10.1016\/j.jbo.2022.100441","journal-title":"J Bone Oncol"}],"updated-by":[{"DOI":"10.1007\/s10142-024-01371-6","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T00:00:00Z","timestamp":1715644800000},"record-id":"53840"},{"DOI":"10.1007\/s10142-024-01371-6","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T00:00:00Z","timestamp":1715644800000}}],"container-title":["Functional & Integrative Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10142-023-01004-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10142-023-01004-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10142-023-01004-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T02:03:12Z","timestamp":1715652192000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10142-023-01004-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["1004"],"URL":"https:\/\/doi.org\/10.1007\/s10142-023-01004-4","relation":{},"ISSN":["1438-793X","1438-7948"],"issn-type":[{"value":"1438-793X","type":"print"},{"value":"1438-7948","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"11 February 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 February 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 February 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 May 2024","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This article has been retracted. Please see the Retraction Notice for more detail:","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s10142-024-01371-6","URL":"https:\/\/doi.org\/10.1007\/s10142-024-01371-6","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The Shanghai Changzhen Hospital and the 72nd Army Hospital approved this case report to be published.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"76"}}