{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T22:35:48Z","timestamp":1768775748329,"version":"3.49.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T00:00:00Z","timestamp":1727222400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T00:00:00Z","timestamp":1727222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Effect of Different Doses of Tributyltin Interference on Embryo Loss Rate in Polycystic Syndrome Pregnancy Model Mice","award":["Zunshi Kehe HZ Zi (2022) No. 246"],"award-info":[{"award-number":["Zunshi Kehe HZ Zi (2022) No. 246"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Funct Integr Genomics"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1007\/s10142-024-01448-2","type":"journal-article","created":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T01:39:16Z","timestamp":1727228356000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Transcription factor YY1 adversely governs ovarian granulosa cell growth in PCOS by transcription activation-mediated CDKN1C upregulation"],"prefix":"10.1007","volume":"24","author":[{"given":"Shitao","family":"Dong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youbin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhimin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,9,25]]},"reference":[{"issue":"3","key":"1448_CR1","doi-asserted-by":"publisher","first-page":"245","DOI":"10.5653\/cerm.2020.04112","volume":"48","author":"R Asghari","year":"2021","unstructured":"Asghari R, Shokri-Asl V, Rezaei H, Tavallaie M, Khafaei M, Abdolmaleki A, Majdi Seghinsara A (2021) Alteration of TGFB1, GDF9, and BMPR2 gene expression in preantral follicles of an estradiol valerate-induced polycystic ovary mouse model can lead to anovulation, polycystic morphology, obesity, and absence of hyperandrogenism. Clin Exp Reprod Med 48(3):245\u2013254. https:\/\/doi.org\/10.5653\/cerm.2020.04112","journal-title":"Clin Exp Reprod Med"},{"issue":"1\u20132","key":"1448_CR2","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.gene.2006.12.012","volume":"391","author":"S Br\u00fbl\u00e9","year":"2007","unstructured":"Br\u00fbl\u00e9 S, Sayasith K, Sirois J, Silversides DW, Lussier JG (2007) Structure of the bovine VASAP-60\/PRKCSH gene, functional analysis of the promoter, and gene expression analysis. Gene 391(1\u20132):63\u201375. https:\/\/doi.org\/10.1016\/j.gene.2006.12.012","journal-title":"Gene"},{"issue":"11","key":"1448_CR3","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.3390\/biom11111602","volume":"11","author":"P Cagle","year":"2021","unstructured":"Cagle P, Qi Q, Niture S, Kumar D (2021) KCNQ1OT1: an oncogenic long noncoding RNA. Biomolecules 11(11):1602. https:\/\/doi.org\/10.3390\/biom11111602","journal-title":"Biomolecules"},{"issue":"8","key":"1448_CR4","doi-asserted-by":"publisher","first-page":"1452","DOI":"10.1128\/mcb.01163-13","volume":"34","author":"A Cerqueira","year":"2014","unstructured":"Cerqueira A, Mart\u00edn A, Symonds CE, Odajima J, Dubus P, Barbacid M, Santamar\u00eda D (2014) Genetic characterization of the role of the Cip\/Kip family of proteins as cyclin-dependent kinase inhibitors and assembly factors. Mol Cell Biol 34(8):1452\u20131459. https:\/\/doi.org\/10.1128\/mcb.01163-13","journal-title":"Mol Cell Biol"},{"issue":"8","key":"1448_CR5","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1038\/s41419-023-05984-w","volume":"14","author":"W Chen","year":"2023","unstructured":"Chen W, Sun EQ, Zhang B, Li P, Fei N, Wang S, Liu Y, Liu S, Zhang X X (2023) PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation. Cell Death Dis 14(8):524. https:\/\/doi.org\/10.1038\/s41419-023-05984-w","journal-title":"Cell Death Dis"},{"issue":"4","key":"1448_CR6","doi-asserted-by":"publisher","first-page":"e58733","DOI":"10.7759\/cureus.58733","volume":"16","author":"R Choudhari","year":"2024","unstructured":"Choudhari R, Tayade S, Tiwari A, Satone P (2024) Diagnosis, management, and Associated comorbidities of Polycystic Ovary Syndrome: a narrative review. Cureus 16(4):e58733. https:\/\/doi.org\/10.7759\/cureus.58733","journal-title":"Cureus"},{"key":"1448_CR7","doi-asserted-by":"publisher","first-page":"584590","DOI":"10.3389\/fcell.2020.584590","volume":"8","author":"J Creff","year":"2020","unstructured":"Creff J, Besson A (2020) Functional versatility of the CDK inhibitor p57(Kip2). Front Cell Dev Biol 8:584590. https:\/\/doi.org\/10.3389\/fcell.2020.584590","journal-title":"Front Cell Dev Biol"},{"issue":"1","key":"1448_CR8","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s13008-024-00115-z","volume":"19","author":"L Csergeov\u00e1","year":"2024","unstructured":"Csergeov\u00e1 L, Krbu\u0161ek D, Jano\u0161tiak R (2024) CIP\/KIP and INK4 families as hostages of oncogenic signaling. Cell Div 19(1):11. https:\/\/doi.org\/10.1186\/s13008-024-00115-z","journal-title":"Cell Div"},{"issue":"3","key":"1448_CR9","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1210\/jc.2007-1650","volume":"93","author":"M Das","year":"2008","unstructured":"Das M, Djahanbakhch O, Hacihanefioglu B, Saridogan E, Ikram M, Ghali L, Raveendran M, Storey A (2008) Granulosa cell survival and proliferation are altered in polycystic ovary syndrome. J Clin Endocrinol Metab 93(3):881\u2013887. https:\/\/doi.org\/10.1210\/jc.2007-1650","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"1448_CR10","doi-asserted-by":"publisher","first-page":"1396","DOI":"10.3390\/cells10061396","volume":"10","author":"C Dompe","year":"2021","unstructured":"Dompe C, Kulus M, Stefa\u0144ska K, Kranc W, Chermu\u0142a B, Bryl R, Pie\u0144kowski W, Nawrocki MJ, Petitte JN, Stelmach B, Mozdziak P, Jeseta M, Pawelczyk L, Ja\u015bkowski JM, Piotrowska-Kempisty H, Spaczy\u0144ski RZ, Nowicki M, Kempisty B (2021) Human granulosa cells-Stemness Properties, Molecular Cross-talk and Follicular Angiogenesis. Cells 10(6):1396. https:\/\/doi.org\/10.3390\/cells10061396","journal-title":"Cells"},{"issue":"4","key":"1448_CR11","doi-asserted-by":"publisher","first-page":"333","DOI":"10.4103\/ijmr.IJMR_1937_17","volume":"150","author":"MA Ganie","year":"2019","unstructured":"Ganie MA, Vasudevan V, Wani IA, Baba MS, Arif T, Rashid A (2019) Epidemiology, pathogenesis, genetics & management of polycystic ovary syndrome in India. Indian J Med Res 150(4):333\u2013344. https:\/\/doi.org\/10.4103\/ijmr.IJMR_1937_17","journal-title":"Indian J Med Res"},{"key":"1448_CR12","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.metabol.2018.11.002","volume":"92","author":"CJ Glueck","year":"2019","unstructured":"Glueck CJ, Goldenberg N (2019) Characteristics of obesity in polycystic ovary syndrome: etiology, treatment, and genetics. Metabolism 92:108\u2013120. https:\/\/doi.org\/10.1016\/j.metabol.2018.11.002","journal-title":"Metabolism"},{"issue":"1","key":"1448_CR13","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/s12958-023-01055-z","volume":"21","author":"D Greff","year":"2023","unstructured":"Greff D, Juh\u00e1sz AE, V\u00e1ncsa S, V\u00e1radi A, Sipos Z, Szinte J, Park S, Hegyi P, Nyir\u00e1dy P, \u00c1cs N, V\u00e1rb\u00edr\u00f3 S, Horv\u00e1th EM (2023) Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. Reprod Biol Endocrinol 21(1):10. https:\/\/doi.org\/10.1186\/s12958-023-01055-z","journal-title":"Reprod Biol Endocrinol"},{"issue":"4","key":"1448_CR14","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1095\/biolreprod.110.087213","volume":"84","author":"GJ Griffith","year":"2011","unstructured":"Griffith GJ, Trask MC, Hiller J, Walentuk M, Pawlak JB, Tremblay KD, Mager J (2011) Yin-yang1 is required in the mammalian oocyte for follicle expansion. Biol Reprod 84(4):654\u2013663. https:\/\/doi.org\/10.1095\/biolreprod.110.087213","journal-title":"Biol Reprod"},{"issue":"7841","key":"1448_CR15","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1038\/s41586-020-3027-9","volume":"589","author":"N Hamazaki","year":"2021","unstructured":"Hamazaki N, Kyogoku H, Araki H, Miura F, Horikawa C, Hamada N, Shimamoto S, Hikabe O, Nakashima K, Kitajima TS, Ito T, Leitch HG, Hayashi K (2021) Reconstitution of the oocyte transcriptional network with transcription factors. Nature 589(7841):264\u2013269. https:\/\/doi.org\/10.1038\/s41586-020-3027-9","journal-title":"Nature"},{"issue":"6","key":"1448_CR16","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1007\/s10616-020-00426-3","volume":"72","author":"Z Hashemian","year":"2020","unstructured":"Hashemian Z, Afsharian P, Farzaneh P, Eftekhari-Yazdi P, Vakhshiteh F, Daneshvar Amoli A, Nasimian A (2020) Establishment and characterization of a PCOS and a normal human granulosa cell line. Cytotechnology 72(6):833\u2013845. https:\/\/doi.org\/10.1007\/s10616-020-00426-3","journal-title":"Cytotechnology"},{"issue":"6","key":"1448_CR17","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1093\/humrep\/deu076","volume":"29","author":"R Homburg","year":"2014","unstructured":"Homburg R, Crawford G (2014) The role of AMH in anovulation associated with PCOS: a hypothesis. Hum Reprod 29(6):1117\u20131121. https:\/\/doi.org\/10.1093\/humrep\/deu076","journal-title":"Hum Reprod"},{"issue":"1","key":"1448_CR18","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/s00795-021-00307-4","volume":"55","author":"M Hu","year":"2022","unstructured":"Hu M, Gao T, Du Y (2022) MiR-98-3p regulates ovarian granulosa cell proliferation and apoptosis in polycystic ovary syndrome by targeting YY1. Med Mol Morphol 55(1):47\u201359. https:\/\/doi.org\/10.1007\/s00795-021-00307-4","journal-title":"Med Mol Morphol"},{"issue":"5","key":"1448_CR19","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1016\/j.prp.2019.01.038","volume":"215","author":"X Huang","year":"2019","unstructured":"Huang X, She L, Luo X, Huang S, Wu J (2019) MiR-222 promotes the progression of polycystic ovary syndrome by targeting p27 Kip1. Pathol Res Pract 215(5):918\u2013923. https:\/\/doi.org\/10.1016\/j.prp.2019.01.038","journal-title":"Pathol Res Pract"},{"issue":"2","key":"1448_CR20","doi-asserted-by":"publisher","first-page":"e22693","DOI":"10.1096\/fj.202201246RR","volume":"37","author":"Q Jiang","year":"2023","unstructured":"Jiang Q, Miao R, Wang Y, Wang W, Zhao D, Niu Y, Ding Q, Li Y, Leung PCK, Wei D, Chen ZJ (2023) ANGPTL4 inhibits granulosa cell proliferation in polycystic ovary syndrome by EGFR\/JAK1\/STAT3-mediated induction of p21. FASEB J 37(2):e22693. https:\/\/doi.org\/10.1096\/fj.202201246RR","journal-title":"FASEB J"},{"issue":"5","key":"1448_CR21","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1016\/j.rbmo.2018.08.005","volume":"37","author":"L Jin","year":"2018","unstructured":"Jin L, Yang Q, Zhou C, Liu L, Wang H, Hou M, Wu Y, Shi F, Sheng J, Huang H (2018) Profiles for long non-coding RNAs in ovarian granulosa cells from women with PCOS with or without hyperandrogenism. Reprod Biomed Online 37(5):613\u2013623. https:\/\/doi.org\/10.1016\/j.rbmo.2018.08.005","journal-title":"Reprod Biomed Online"},{"issue":"9","key":"1448_CR22","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1016\/s2213-8587(22)00163-2","volume":"10","author":"AE Joham","year":"2022","unstructured":"Joham AE, Norman RJ, Stener-Victorin E, Legro RS, Franks S, Moran LJ, Boyle J, Teede HJ (2022) Polycystic ovary syndrome. Lancet Diabetes Endocrinol 10(9):668\u2013680. https:\/\/doi.org\/10.1016\/s2213-8587(22)00163-2","journal-title":"Lancet Diabetes Endocrinol"},{"key":"1448_CR23","doi-asserted-by":"publisher","first-page":"249","DOI":"10.2147\/tacg.s200341","volume":"12","author":"MJ Khan","year":"2019","unstructured":"Khan MJ, Ullah A, Basit S (2019) Genetic basis of polycystic ovary syndrome (PCOS): current perspectives. Appl Clin Genet 12:249\u2013260. https:\/\/doi.org\/10.2147\/tacg.s200341","journal-title":"Appl Clin Genet"},{"issue":"2","key":"1448_CR24","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/s0092-8674(03)01080-8","volume":"116","author":"AW Murray","year":"2004","unstructured":"Murray AW (2004) Recycling the cell cycle: cyclins revisited. Cell 116(2):221\u2013234. https:\/\/doi.org\/10.1016\/s0092-8674(03)01080-8","journal-title":"Cell"},{"issue":"2","key":"1448_CR25","doi-asserted-by":"publisher","first-page":"201","DOI":"10.2174\/1570180819666220512140651","volume":"20","author":"B Nickavar","year":"2023","unstructured":"Nickavar B, Nickavar A (2023) Compositional analysis of essential oils from Two Mentha Species and in silico study on their major volatile constituents against polycystic ovary syndrome. Lett Drug Des Discov 20(2):201\u2013212. https:\/\/doi.org\/10.2174\/1570180819666220512140651","journal-title":"Lett Drug Des Discov"},{"issue":"3","key":"1448_CR26","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1007\/s10815-022-02429-9","volume":"39","author":"ALG Notaro","year":"2022","unstructured":"Notaro ALG, Neto FTL (2022) The use of metformin in women with polycystic ovary syndrome: an updated review. J Assist Reprod Genet 39(3):573\u2013579. https:\/\/doi.org\/10.1007\/s10815-022-02429-9","journal-title":"J Assist Reprod Genet"},{"key":"1448_CR27","doi-asserted-by":"publisher","unstructured":"Regan SLP, Knight PG, Yovich JL, Leung Y, Arfuso F, Dharmarajan A (2018) Granulosa Cell apoptosis in the ovarian Follicle-A changing view. Front Endocrinol (Lausanne) 961. https:\/\/doi.org\/10.3389\/fendo.2018.00061","DOI":"10.3389\/fendo.2018.00061"},{"key":"1448_CR28","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.3389\/fonc.2019.01230","volume":"9","author":"S Sarvagalla","year":"2019","unstructured":"Sarvagalla S, Kolapalli SP, Vallabhapurapu S (2019) The two sides of YY1 in Cancer: a friend and a foe. Front Oncol 9:1230. https:\/\/doi.org\/10.3389\/fonc.2019.01230","journal-title":"Front Oncol"},{"issue":"1","key":"1448_CR29","doi-asserted-by":"publisher","first-page":"14738","DOI":"10.1038\/s41598-020-71418-8","volume":"10","author":"M Sharma","year":"2020","unstructured":"Sharma M, Barai RS, Kundu I, Bhaye S, Pokar K, Idicula-Thomas S (2020) PCOSKB(R2): a database of genes, diseases, pathways, and networks associated with polycystic ovary syndrome. Sci Rep 10(1):14738. https:\/\/doi.org\/10.1038\/s41598-020-71418-8","journal-title":"Sci Rep"},{"issue":"4","key":"1448_CR30","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.3390\/jcm12041454","volume":"12","author":"S Singh","year":"2023","unstructured":"Singh S, Pal N, Shubham S, Sarma DK, Verma V, Marotta F, Kumar M (2023) Polycystic ovary syndrome: etiology, current management, and future therapeutics. J Clin Med 12(4):1454. https:\/\/doi.org\/10.3390\/jcm12041454","journal-title":"J Clin Med"},{"issue":"10","key":"1448_CR31","doi-asserted-by":"publisher","first-page":"2094","DOI":"10.1038\/s41375-023-02006-8","volume":"37","author":"A Sircar","year":"2023","unstructured":"Sircar A, Singh S, Xu-Monette ZY, Coyle KM, Hilton LK, Chavdoula E, Ranganathan P, Jain N, Hanel W, Tsichlis P, Alinari L, Peterson BR, Tao J, Muthusamy N, Baiocchi R, Epperla N, Young KH, Morin R, Sehgal L (2023) Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in Mantle cell lymphoma. Leukemia 37(10):2094\u20132106. https:\/\/doi.org\/10.1038\/s41375-023-02006-8","journal-title":"Leukemia"},{"issue":"4","key":"1448_CR32","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.3390\/ijms19041055","volume":"19","author":"E Stampone","year":"2018","unstructured":"Stampone E, Caldarelli I, Zullo A, Bencivenga D, Mancini FP, Della Ragione F, Borriello A (2018) Genetic and epigenetic control of CDKN1C expression: importance in cell commitment and differentiation, tissue homeostasis and human diseases. Int J Mol Sci 19(4):1055. https:\/\/doi.org\/10.3390\/ijms19041055","journal-title":"Int J Mol Sci"},{"key":"1448_CR33","doi-asserted-by":"publisher","first-page":"592164","DOI":"10.3389\/fcell.2020.592164","volume":"8","author":"TCJ Verheul","year":"2020","unstructured":"Verheul TCJ, van Hijfte L, Perenthaler E, Barakat TS (2020) The why of YY1: mechanisms of Transcriptional Regulation by Yin Yang 1. Front Cell Dev Biol 8:592164. https:\/\/doi.org\/10.3389\/fcell.2020.592164","journal-title":"Front Cell Dev Biol"},{"issue":"4","key":"1448_CR34","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1073\/pnas.95.4.1392","volume":"95","author":"H Watanabe","year":"1998","unstructured":"Watanabe H, Pan ZQ, Schreiber-Agus N, DePinho RA, Hurwitz J, Xiong Y (1998) Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57KIP2 requires binding to proliferating cell nuclear antigen. Proc Natl Acad Sci U S A 95(4):1392\u20131397. https:\/\/doi.org\/10.1073\/pnas.95.4.1392","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"8","key":"1448_CR35","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1210\/js.2019-00078","volume":"3","author":"SF Witchel","year":"2019","unstructured":"Witchel SF, Oberfield SE, Pe\u00f1a AS (2019) Polycystic ovary syndrome: pathophysiology, presentation, and treatment with emphasis on adolescent girls. J Endocr Soc 3(8):1545\u20131573. https:\/\/doi.org\/10.1210\/js.2019-00078","journal-title":"J Endocr Soc"},{"issue":"6","key":"1448_CR36","doi-asserted-by":"publisher","first-page":"1817","DOI":"10.1111\/jcmm.16231","volume":"26","author":"G Wu","year":"2022","unstructured":"Wu G, Xia J, Yang Z, Chen Y, Jiang W, Yin T, Yang J (2022) CircASPH promotes KGN cells proliferation through miR-375\/MAP2K6 axis in polycystic ovary syndrome. J Cell Mol Med 26(6):1817\u20131825. https:\/\/doi.org\/10.1111\/jcmm.16231","journal-title":"J Cell Mol Med"},{"issue":"2","key":"1448_CR37","doi-asserted-by":"publisher","first-page":"108522","DOI":"10.1016\/j.isci.2023.108522","volume":"27","author":"Z Yang","year":"2024","unstructured":"Yang Z, Pan J, Zhou C, Yu C, Zhou Z, Ding G, Liu X, Sheng J, Jin L, Huang H (2024) LncRNA SNHG5 adversely governs follicular growth in PCOS via miR-92a-3p\/CDKN1C axis. iScience 27(2):108522. https:\/\/doi.org\/10.1016\/j.isci.2023.108522","journal-title":"iScience"},{"issue":"1","key":"1448_CR38","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/s13048-022-00962-w","volume":"15","author":"J Zou","year":"2022","unstructured":"Zou J, Li Y, Liao N, Liu J, Zhang Q, Luo M, Xiao J, Chen Y, Wang M, Chen K, Zeng J, Mo Z (2022) Identification of key genes associated with polycystic ovary syndrome (PCOS) and ovarian cancer using an integrated bioinformatics analysis. J Ovarian Res 15(1):30. https:\/\/doi.org\/10.1186\/s13048-022-00962-w","journal-title":"J Ovarian Res"}],"container-title":["Functional &amp; Integrative Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10142-024-01448-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10142-024-01448-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10142-024-01448-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T16:15:41Z","timestamp":1730218541000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10142-024-01448-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,25]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["1448"],"URL":"https:\/\/doi.org\/10.1007\/s10142-024-01448-2","relation":{},"ISSN":["1438-793X","1438-7948"],"issn-type":[{"value":"1438-793X","type":"print"},{"value":"1438-7948","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,25]]},"assertion":[{"value":"18 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 September 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 September 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 September 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This research was approved by the Ethics Committee of Affiliated Hospital of Zunyi Medical University.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"171"}}