{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T06:19:58Z","timestamp":1788589198568,"version":"build-2803163510"},"reference-count":156,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T00:00:00Z","timestamp":1507852800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurosurg Rev"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1007\/s10143-017-0910-4","type":"journal-article","created":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T02:22:37Z","timestamp":1507861357000},"page":"209-226","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Accelerated growth of hemangioblastoma in pregnancy: the role of proangiogenic factors and upregulation of hypoxia-inducible factor (HIF) in a non-oxygen-dependent pathway"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5386-9939","authenticated-orcid":false,"given":"Yosef","family":"Laviv","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua L.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew P.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekkehard M.","family":"Kasper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,10,13]]},"reference":[{"key":"910_CR1","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1161\/01.ATV.0000110502.10593.06","volume":"24","author":"MR Abid","year":"2004","unstructured":"Abid MR, Guo S, Minami T, Spokes KC, Ueki K, Skurk C, Walsh K, Aird WC (2004) Vascular endothelial growth factor activates PI3K\/Akt\/forkhead signaling in endothelial cells. Arterioscler Thromb Vasc Biol 24:294\u2013300","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"910_CR2","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1002\/cbf.3176","volume":"34","author":"H Akrami","year":"2016","unstructured":"Akrami H, Mahmoodi F, Havasi S, Sharifi A (2016) PlGF knockdown inhibited tumor survival and migration in gastric cancer cell via PI3K\/Akt and p38MAPK pathways. Cell Biochem Funct 34:173\u2013180. https:\/\/doi.org\/10.1002\/cbf.3176","journal-title":"Cell Biochem Funct"},{"key":"910_CR3","doi-asserted-by":"publisher","first-page":"7455","DOI":"10.1038\/sj.onc.1209085","volume":"24","author":"DA Altomare","year":"2005","unstructured":"Altomare DA, Testa JR (2005) Perturbations of the AKT signaling pathway in human cancer. Oncogene 24:7455\u20137464","journal-title":"Oncogene"},{"key":"910_CR4","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1161\/HYPERTENSIONAHA.110.158931","volume":"56","author":"OA Amburgey","year":"2010","unstructured":"Amburgey OA, Chapman AC, May V, Bernstein IM, Cipolla MJ (2010) Plasma from preeclamptic women increases blood-brain barrier permeability: role of vascular endothelial growth factor signaling. Hypertension 56:1003\u20131008. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.1110.158931","journal-title":"Hypertension"},{"key":"910_CR5","doi-asserted-by":"publisher","first-page":"7546","DOI":"10.1128\/MCB.25.17.7546-7556.2005","volume":"25","author":"J An","year":"2005","unstructured":"An J, Rettig MB (2005) Mechanism of von Hippel-Lindau protein-mediated suppression of nuclear factor kappa B activity. Mol Cell Biol 25:7546\u20137556","journal-title":"Mol Cell Biol"},{"key":"910_CR6","doi-asserted-by":"publisher","first-page":"1356","DOI":"10.1046\/j.1538-7836.2003.00263.x","volume":"1","author":"M Autiero","year":"2003","unstructured":"Autiero M, Luttun A, Tjwa M, Carmeliet P (2003) Placental growth factor and its receptor, vascular endothelial growth factor receptor-1: novel targets for stimulation of ischemic tissue revascularization and inhibition of angiogenic and inflammatory disorders. J Thromb Haemost 1:1356\u20131370","journal-title":"J Thromb Haemost"},{"key":"910_CR7","doi-asserted-by":"publisher","first-page":"E9","DOI":"10.3171\/foc.2007.22.5.10","volume":"22","author":"MA Baggenstos","year":"2007","unstructured":"Baggenstos MA, Butman JA, Oldfield EH, Lonser RR (2007) Role of edema in peritumoral cyst formation. Neurosurg Focus 22:E9","journal-title":"Neurosurg Focus"},{"key":"910_CR8","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1016\/0029-7844(95)00259-T","volume":"86","author":"PN Baker","year":"1995","unstructured":"Baker PN, Krasnow J, Roberts JM, Yeo KT (1995) Elevated serum levels of vascular endothelial growth factor in patients with preeclampsia. Obstet Gynecol 86:815\u2013821","journal-title":"Obstet Gynecol"},{"key":"910_CR9","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1038\/sj.bjp.0706347","volume":"146","author":"L Bellik","year":"2005","unstructured":"Bellik L, Vinci MC, Filippi S, Ledda F, Parenti A (2005) Intracellular pathways triggered by the selective FLT-1-agonist placental growth factor in vascular smooth muscle cells exposed to hypoxia. Br J Pharmacol 146:568\u2013575","journal-title":"Br J Pharmacol"},{"key":"910_CR10","doi-asserted-by":"publisher","first-page":"e0163096","DOI":"10.1371\/journal.pone.0163096","volume":"11","author":"NK Binder","year":"2016","unstructured":"Binder NK, Evans J, Salamonsen LA, Gardner DK, Kaitu\u2019u-Lino TJ, Hannan NJ (2016) Placental growth factor is secreted by the human endometrium and has potential important functions during embryo development and implantation. PLoS One 11:e0163096. https:\/\/doi.org\/10.1371\/journal.pone.0163096.eCollection2016","journal-title":"PLoS One"},{"key":"910_CR11","doi-asserted-by":"crossref","unstructured":"Blakeley JO, Ye X, Duda DG, Halpin CF, Bergner AL, Muzikansky A, Merker VL, Gerstner ER, Fayad LM, Ahlawat S, Jacobs MA, Jain RK, Zalewski C, Dombi E, Widemann BC, Plotkin SR (2016) Efficacy and biomarker study of bevacizumab for hearing loss resulting from neurofibromatosis type 2-associated vestibular schwannomas. J Clin Oncol 34(14):1669\u20131675","DOI":"10.1200\/JCO.2015.64.3817"},{"key":"910_CR12","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1165\/rcmb.2011-0152OC","volume":"46","author":"S Bobic","year":"2012","unstructured":"Bobic S, Seys S, De Vooght V, Callebaut I, Hox V, Dooms C, Vinckier S, Jonckx B, Saint-Remy JM, Stassen JM, Bullens DM, Ceuppens JL, Carmeliet P, Hellings PW (2012) Placental growth factor contributes to bronchial neutrophilic inflammation and edema in allergic asthma. Am J Respir Cell Mol Biol 46:781\u2013789. https:\/\/doi.org\/10.1165\/rcmb.2011-0152OC","journal-title":"Am J Respir Cell Mol Biol"},{"key":"910_CR13","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1097\/00005072-199605000-00004","volume":"55","author":"T Bohling","year":"1996","unstructured":"Bohling T, Hatva E, Kujala M, Claesson-Welsh L, Alitalo K, Haltia M (1996) Expression of growth factors and growth factor receptors in capillary hemangioblastoma. J Neuropathol Exp Neurol 55:522\u2013527","journal-title":"J Neuropathol Exp Neurol"},{"key":"910_CR14","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1007\/BF03014969","volume":"48","author":"A Boker","year":"2001","unstructured":"Boker A, Ong BY (2001) Anesthesia for Cesarean section and posterior fossa craniotomy in a patient with von Hippel-Lindau disease. Can J Anaesth 48:387\u2013390","journal-title":"Can J Anaesth"},{"key":"910_CR15","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1136\/jnnp.30.6.559","volume":"30","author":"PJ Bourdillon","year":"1967","unstructured":"Bourdillon PJ, Hickman RC (1967) Von Hippel-Lindau\u2019s disease presenting at an early age. J Neurol Neurosurg Psychiatry 30:559\u2013562","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"910_CR16","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1111\/j.1600-0447.1949.tb07318.x","volume":"24","author":"B Broager","year":"1949","unstructured":"Broager B (1949) Multiple cerebellar angioreticulomas; discussion of high protein contents of the cysts and of enclosed parts of the subarachnoid space. Acta Psychiatr Neurol 24:317\u2013332","journal-title":"Acta Psychiatr Neurol"},{"key":"910_CR17","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1042\/cs0770599","volume":"77","author":"MA Brown","year":"1989","unstructured":"Brown MA, Zammit VC, Lowe SA (1989) Capillary permeability and extracellular fluid volumes in pregnancy-induced hypertension. Clin Sci (Lond) 77:599\u2013604","journal-title":"Clin Sci (Lond)"},{"key":"910_CR18","doi-asserted-by":"publisher","first-page":"2507","DOI":"10.1172\/JCI119069","volume":"98","author":"Y Cao","year":"1996","unstructured":"Cao Y, Linden P, Shima D, Browne F, Folkman J (1996) In vivo angiogenic activity and hypoxia induction of heterodimers of placenta growth factor\/vascular endothelial growth factor. J Clin Invest 98:2507\u20132511","journal-title":"J Clin Invest"},{"key":"910_CR19","doi-asserted-by":"publisher","first-page":"e27","DOI":"10.1016\/j.spinee.2013.07.428","volume":"13","author":"F Capone","year":"2013","unstructured":"Capone F, Profice P, Pilato F, Zollino M, Colosimo C, Di Lazzaro V (2013) Spinal hemangioblastoma presenting with low back pain in pregnancy. Spine J 13:e27\u2013e29. https:\/\/doi.org\/10.1016\/j.spinee.2013.1007.1428","journal-title":"Spine J"},{"key":"910_CR20","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1038\/74651","volume":"6","author":"P Carmeliet","year":"2000","unstructured":"Carmeliet P (2000) Mechanisms of angiogenesis and arteriogenesis. Nat Med 6:389\u2013395","journal-title":"Nat Med"},{"key":"910_CR21","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1038\/87904","volume":"7","author":"P Carmeliet","year":"2001","unstructured":"Carmeliet P, Moons L, Luttun A, Vincenti V, Compernolle V, De Mol M, Wu Y, Bono F, Devy L, Beck H, Scholz D, Acker T, DiPalma T, Dewerchin M, Noel A, Stalmans I, Barra A, Blacher S, VandenDriessche T, Ponten A, Eriksson U, Plate KH, Foidart JM, Schaper W, Charnock-Jones DS, Hicklin DJ, Herbert JM, Collen D, Persico MG (2001) Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med 7:575\u2013583","journal-title":"Nat Med"},{"key":"910_CR22","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.tcm.2012.07.022","volume":"22","author":"D Carnevale","year":"2012","unstructured":"Carnevale D, Lembo G (2012) Placental growth factor and cardiac inflammation. Trends Cardiovasc Med 22:209\u2013212. https:\/\/doi.org\/10.1016\/j.tcm.2012.1007.1022","journal-title":"Trends Cardiovasc Med"},{"key":"910_CR23","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1080\/14767050400028816","volume":"17","author":"T Chaiworapongsa","year":"2005","unstructured":"Chaiworapongsa T, Romero R, Kim YM, Kim GJ, Kim MR, Espinoza J, Bujold E, Goncalves L, Gomez R, Edwin S, Mazor M (2005) Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia. J Matern Fetal Neonatal Med 17:3\u201318","journal-title":"J Matern Fetal Neonatal Med"},{"key":"910_CR24","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.2353\/ajpath.2006.051314","volume":"169","author":"F Cianfarani","year":"2006","unstructured":"Cianfarani F, Zambruno G, Brogelli L, Sera F, Lacal PM, Pesce M, Capogrossi MC, Failla CM, Napolitano M, Odorisio T (2006) Placenta growth factor in diabetic wound healing: altered expression and therapeutic potential. Am J Pathol 169:1167\u20131182","journal-title":"Am J Pathol"},{"key":"910_CR25","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1161\/HYPERTENSIONAHA.106.079442","volume":"50","author":"MJ Cipolla","year":"2007","unstructured":"Cipolla MJ (2007) Cerebrovascular function in pregnancy and eclampsia. Hypertension 50:14\u201324","journal-title":"Hypertension"},{"key":"910_CR26","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1111\/joim.12019","volume":"273","author":"L Claesson-Welsh","year":"2013","unstructured":"Claesson-Welsh L, Welsh M (2013) VEGFA and tumour angiogenesis. J Intern Med 273:114\u2013127. https:\/\/doi.org\/10.1111\/joim.12019","journal-title":"J Intern Med"},{"key":"910_CR27","doi-asserted-by":"publisher","first-page":"1470","DOI":"10.1172\/JCI114322","volume":"84","author":"DT Connolly","year":"1989","unstructured":"Connolly DT, Heuvelman DM, Nelson R, Olander JV, Eppley BL, Delfino JJ, Siegel NR, Leimgruber RM, Feder J (1989) Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 84:1470\u20131478","journal-title":"J Clin Invest"},{"key":"910_CR28","first-page":"55","volume":"48","author":"JE Conway","year":"2001","unstructured":"Conway JE, Chou D, Clatterbuck RE, Brem H, Long DM, Rigamonti D (2001) Hemangioblastomas of the central nervous system in von Hippel-Lindau syndrome and sporadic disease. Neurosurgery 48:55\u201362 discussion 62-53","journal-title":"Neurosurgery"},{"key":"910_CR29","first-page":"277","volume":"66","author":"GR Criscuolo","year":"1993","unstructured":"Criscuolo GR (1993) The genesis of peritumoral vasogenic brain edema and tumor cysts: a hypothetical role for tumor-derived vascular permeability factor. Yale J Biol Med 66:277\u2013314","journal-title":"Yale J Biol Med"},{"key":"910_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3858\/emm.2012.44.1.025","volume":"44","author":"S Falco De","year":"2012","unstructured":"De Falco S (2012) The discovery of placenta growth factor and its biological activity. Exp Mol Med 44:1\u20139. https:\/\/doi.org\/10.3858\/emm.2012.3844.3851.3025","journal-title":"Exp Mol Med"},{"key":"910_CR31","first-page":"242","volume":"9","author":"MF Delisle","year":"2000","unstructured":"Delisle MF, Valimohamed F, Money D, Douglas MJ (2000) Central nervous system complications of von Hippel-Lindau disease and pregnancy; perinatal considerations: case report and literature review. J Matern Fetal Med 9:242\u2013247","journal-title":"J Matern Fetal Med"},{"key":"910_CR32","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/j.biocel.2004.08.012","volume":"37","author":"MA Dery","year":"2005","unstructured":"Dery MA, Michaud MD, Richard DE (2005) Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators. Int J Biochem Cell Biol 37:535\u2013540","journal-title":"Int J Biochem Cell Biol"},{"key":"910_CR33","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1002\/(SICI)1096-9896(199909)189:1<66::AID-PATH390>3.0.CO;2-X","volume":"189","author":"S Donnini","year":"1999","unstructured":"Donnini S, Machein MR, Plate KH, Weich HA (1999) Expression and localization of placenta growth factor and PlGF receptors in human meningiomas. J Pathol 189:66\u201371","journal-title":"J Pathol"},{"key":"910_CR34","first-page":"118","volume":"52","author":"B Dupperat","year":"1945","unstructured":"Dupperat B (1945) Tumeurs cerebrales et grossesse. Pr Med 52:118","journal-title":"Pr Med"},{"key":"910_CR35","first-page":"864","volume":"47","author":"B Erdogan","year":"2002","unstructured":"Erdogan B, Sen O, Aydin MV, Bagis T, Bavbek M (2002) Cerebellar hemangioblastoma in pregnancy. A case report. J Reprod Med 47:864\u2013866","journal-title":"J Reprod Med"},{"key":"910_CR36","doi-asserted-by":"publisher","first-page":"2103","DOI":"10.1016\/S0140-6736(07)61904-7","volume":"370","author":"B Escudier","year":"2007","unstructured":"Escudier B, Pluzanska A, Koralewski P, Ravaud A, Bracarda S, Szczylik C, Chevreau C, Filipek M, Melichar B, Bajetta E, Gorbunova V, Bay JO, Bodrogi I, Jagiello-Gruszfeld A, Moore N (2007) Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 370:2103\u20132111","journal-title":"Lancet"},{"key":"910_CR37","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1042\/cs0920567","volume":"92","author":"P Evans","year":"1997","unstructured":"Evans P, Wheeler T, Anthony F, Osmond C (1997) Maternal serum vascular endothelial growth factor during early pregnancy. Clin Sci (Lond) 92:567\u2013571","journal-title":"Clin Sci (Lond)"},{"key":"910_CR38","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1093\/humrep\/13.4.1057","volume":"13","author":"PW Evans","year":"1998","unstructured":"Evans PW, Wheeler T, Anthony FW, Osmond C (1998) A longitudinal study of maternal serum vascular endothelial growth factor in early pregnancy. Hum Reprod 13:1057\u20131062","journal-title":"Hum Reprod"},{"key":"910_CR39","doi-asserted-by":"crossref","unstructured":"Feldman MJ, Sizdahkhani S, Edwards NA, Merrill MJ, Ray-Chaudhury A, Zhuang Z, Lonser RR, Oldfield EH, Chittiboina P (2016) Loss of quiescence in von Hippel-Lindau hemangioblastomas is associated with erythropoietin signaling. Sci Rep 6:35486","DOI":"10.1038\/srep35486"},{"key":"910_CR40","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1007\/BF01401323","volume":"71","author":"L Ferrante","year":"1984","unstructured":"Ferrante L, Celli P, Fraioli B, Santoro A (1984) Haemangioblastomas of the posterior cranial fossa. Acta Neurochir 71:283\u2013294","journal-title":"Acta Neurochir"},{"key":"910_CR41","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1016\/j.cell.2007.08.038","volume":"131","author":"C Fischer","year":"2007","unstructured":"Fischer C, Jonckx B, Mazzone M, Zacchigna S, Loges S, Pattarini L, Chorianopoulos E, Liesenborghs L, Koch M, De Mol M, Autiero M, Wyns S, Plaisance S, Moons L, van Rooijen N, Giacca M, Stassen JM, Dewerchin M, Collen D, Carmeliet P (2007) Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels. Cell 131:463\u2013475","journal-title":"Cell"},{"key":"910_CR42","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1038\/nrc2524","volume":"8","author":"C Fischer","year":"2008","unstructured":"Fischer C, Mazzone M, Jonckx B, Carmeliet P (2008) FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy? Nat Rev Cancer 8:942\u2013956. https:\/\/doi.org\/10.1038\/nrc2524","journal-title":"Nat Rev Cancer"},{"key":"910_CR43","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1212\/WNL.0b013e3182661f3c","volume":"79","author":"C Frantzen","year":"2012","unstructured":"Frantzen C, Kruizinga RC, van Asselt SJ, Zonnenberg BA, Lenders JW, de Herder WW, Walenkamp AM, Giles RH, Hes FJ, Sluiter WJ, van Pampus MG, Links TP (2012) Pregnancy-related hemangioblastoma progression and complications in von Hippel-Lindau disease. Neurology 79:793\u2013796","journal-title":"Neurology"},{"key":"910_CR44","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.ccr.2006.08.007","volume":"10","author":"S Ghosh","year":"2006","unstructured":"Ghosh S, Tergaonkar V, Rothlin CV, Correa RG, Bottero V, Bist P, Verma IM, Hunter T (2006) Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival. Cancer Cell 10:215\u2013226","journal-title":"Cancer Cell"},{"key":"910_CR45","doi-asserted-by":"publisher","first-page":"549","DOI":"10.4161\/cbt.5.5.2657","volume":"5","author":"S Glasker","year":"2006","unstructured":"Glasker S, Vortmeyer AO, Lonser RR, Lubensky IA, Okamoto H, Xia JB, Li J, Milne E, Kowalak JA, Oldfield EH, Zhuang Z (2006) Proteomic analysis of hemangioblastoma cyst fluid. Cancer Biol Ther 5:549\u2013553","journal-title":"Cancer Biol Ther"},{"key":"910_CR46","first-page":"2696","volume":"61","author":"CJ Green","year":"2001","unstructured":"Green CJ, Lichtlen P, Huynh NT, Yanovsky M, Laderoute KR, Schaffner W, Murphy BJ (2001) Placenta growth factor gene expression is induced by hypoxia in fibroblasts: a central role for metal transcription factor-1. Cancer Res 61:2696\u20132703","journal-title":"Cancer Res"},{"key":"910_CR47","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/S0002-9378(99)70158-4","volume":"180","author":"P Grimbert","year":"1999","unstructured":"Grimbert P, Chauveau D, Remy SR, Grunfeld JP (1999) Pregnancy in von Hippel-Lindau disease. Am J Obstet Gynecol 180:110\u2013111","journal-title":"Am J Obstet Gynecol"},{"key":"910_CR48","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1084\/jem.20080108","volume":"205","author":"T Hagemann","year":"2008","unstructured":"Hagemann T, Lawrence T, McNeish I, Charles KA, Kulbe H, Thompson RG, Robinson SC, Balkwill FR (2008) \u201cRe-educating\u201d tumor-associated macrophages by targeting NF-kappaB. J Exp Med 205:1261\u20131268. https:\/\/doi.org\/10.1084\/jem.20080108","journal-title":"J Exp Med"},{"key":"910_CR49","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.ijoa.2014.08.008","volume":"24","author":"D Hallsworth","year":"2015","unstructured":"Hallsworth D, Thompson J, Wilkinson D, Kerr RS, Russell R (2015) Intracranial pressure monitoring and caesarean section in a patient with von Hippel-Lindau disease and symptomatic cerebellar haemangioblastomas. Int J Obstet Anesth 24:73\u201377","journal-title":"Int J Obstet Anesth"},{"key":"910_CR50","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1038\/nm740","volume":"8","author":"K Hattori","year":"2002","unstructured":"Hattori K, Heissig B, Wu Y, Dias S, Tejada R, Ferris B, Hicklin DJ, Zhu Z, Bohlen P, Witte L, Hendrikx J, Hackett NR, Crystal RG, Moore MA, Werb Z, Lyden D, Rafii S (2002) Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment. Nat Med 8:841\u2013849","journal-title":"Nat Med"},{"key":"910_CR51","first-page":"763","volume":"148","author":"E Hatva","year":"1996","unstructured":"Hatva E, Bohling T, Jaaskelainen J, Persico MG, Haltia M, Alitalo K (1996) Vascular growth factors and receptors in capillary hemangioblastomas and hemangiopericytomas. Am J Pathol 148:763\u2013775","journal-title":"Am J Pathol"},{"key":"910_CR52","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.2176\/nmc.50.1105","volume":"50","author":"S Hayashi","year":"2010","unstructured":"Hayashi S, Takeda N, Komura E (2010) Symptomatic cerebellar hemorrhage from recurrent hemangioblastoma during delivery. Case report. Neurol Med Chir (Tokyo) 50:1105\u20131107","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"910_CR53","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/j.jocn.2008.05.032","volume":"16","author":"MG Hayden","year":"2009","unstructured":"Hayden MG, Gephart R, Kalanithi P, Chou D (2009) Von Hippel-Lindau disease in pregnancy: a brief review. J Clin Neurosci 16:611\u2013613. https:\/\/doi.org\/10.1016\/j.jocn.2008.1005.1032","journal-title":"J Clin Neurosci"},{"key":"910_CR54","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1128\/MCB.25.1.355-363.2005","volume":"25","author":"S Hiratsuka","year":"2005","unstructured":"Hiratsuka S, Kataoka Y, Nakao K, Nakamura K, Morikawa S, Tanaka S, Katsuki M, Maru Y, Shibuya M (2005) Vascular endothelial growth factor A (VEGF-A) is involved in guidance of VEGF receptor-positive cells to the anterior portion of early embryos. Mol Cell Biol 25:355\u2013363","journal-title":"Mol Cell Biol"},{"key":"910_CR55","first-page":"1207","volume":"61","author":"S Hiratsuka","year":"2001","unstructured":"Hiratsuka S, Maru Y, Okada A, Seiki M, Noda T, Shibuya M (2001) Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis. Cancer Res 61:1207\u20131213","journal-title":"Cancer Res"},{"key":"910_CR56","doi-asserted-by":"publisher","first-page":"9349","DOI":"10.1073\/pnas.95.16.9349","volume":"95","author":"S Hiratsuka","year":"1998","unstructured":"Hiratsuka S, Minowa O, Kuno J, Noda T, Shibuya M (1998) Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc Natl Acad Sci U S A 95:9349\u20139354","journal-title":"Proc Natl Acad Sci U S A"},{"key":"910_CR57","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.canlet.2006.10.005","volume":"250","author":"MC Ho","year":"2007","unstructured":"Ho MC, Chen CN, Lee H, Hsieh FJ, Shun CT, Chang CL, Lai YT, Lee PH (2007) Placenta growth factor not vascular endothelial growth factor A or C can predict the early recurrence after radical resection of hepatocellular carcinoma. Cancer Lett 250:237\u2013249","journal-title":"Cancer Lett"},{"key":"910_CR58","first-page":"534","volume":"43","author":"JV Hoeve","year":"1923","unstructured":"Hoeve JV (1923) Eye diseases in tuberous sclerosis of the brain and in Recklinghausen\u2019s disease. Trans Ophthalmol Soc U K 43:534\u2013541","journal-title":"Trans Ophthalmol Soc U K"},{"key":"910_CR59","doi-asserted-by":"publisher","first-page":"66","DOI":"10.2174\/1874364101004010066","volume":"4","author":"FN Hrisomalos","year":"2010","unstructured":"Hrisomalos FN, Maturi RK, Pata V (2010) Long-term use of intravitreal bevacizumab (avastin) for the treatment of von hippel-lindau associated retinal hemangioblastomas. Open Ophthalmol J 4:66\u201369","journal-title":"Open Ophthalmol J"},{"key":"910_CR60","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/s10143-012-0401-6","volume":"36","author":"A Ilhan-Mutlu","year":"2013","unstructured":"Ilhan-Mutlu A, Wagner L, Widhalm G, Wohrer A, Bartsch S, Czech T, Heinzl H, Leutmezer F, Prayer D, Marosi C, Base W, Preusser M (2013) Exploratory investigation of eight circulating plasma markers in brain tumor patients. Neurosurg Rev 36:45\u201355; discussion 55-46. https:\/\/doi.org\/10.1007\/s10143-10012-10401-10146","journal-title":"Neurosurg Rev"},{"key":"910_CR61","doi-asserted-by":"publisher","first-page":"2993","DOI":"10.1158\/1078-0432.CCR-15-1839","volume":"22","author":"J Incio","year":"2016","unstructured":"Incio J, Tam J, Rahbari NN, Suboj P, McManus DT, Chin SM, Vardam TD, Batista A, Babykutty S, Jung K, Khachatryan A, Hato T, Ligibel JA, Krop IE, Puchner SB, Schlett CL, Hoffmman U, Ancukiewicz M, Shibuya M, Carmeliet P, Soares R, Duda DG, Jain RK, Fukumura D (2016) PlGF\/VEGFR-1 signaling promotes macrophage polarization and accelerated tumor progression in obesity. Clin Cancer Res 22:2993\u20133004. https:\/\/doi.org\/10.1158\/1078-0432.CCR-2915-1839","journal-title":"Clin Cancer Res"},{"key":"910_CR62","first-page":"57","volume":"43","author":"A Inoue","year":"2015","unstructured":"Inoue A, Kohno S, Kumon Y, Watanabe H, Ohnishi T, Hashimoto H, Matsubara K (2015) A case of cerebellar hemangioblastoma complicated by pregnancy and concerns about the surgical period. No Shinkei Geka 43:57\u201362","journal-title":"No Shinkei Geka"},{"key":"910_CR63","doi-asserted-by":"publisher","first-page":"210","DOI":"10.3171\/JNS\/2008\/108\/2\/0210","volume":"108","author":"J Jagannathan","year":"2008","unstructured":"Jagannathan J, Lonser RR, Smith R, DeVroom HL, Oldfield EH (2008) Surgical management of cerebellar hemangioblastomas in patients with von Hippel-Lindau disease. J Neurosurg 108:210\u2013222. https:\/\/doi.org\/10.3171\/JNS\/2008\/3108\/3172\/0210","journal-title":"J Neurosurg"},{"key":"910_CR64","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1136\/jnnp.38.2.105","volume":"38","author":"R Jeffreys","year":"1975","unstructured":"Jeffreys R (1975) Clinical and surgical aspects of posterior fossa haemangioblastomata. J Neurol Neurosurg Psychiatry 38:105\u2013111","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"910_CR65","first-page":"4845","volume":"54","author":"H Kanno","year":"1994","unstructured":"Kanno H, Kondo K, Ito S, Yamamoto I, Fujii S, Torigoe S, Sakai N, Hosaka M, Shuin T, Yao M (1994) Somatic mutations of the von Hippel-Lindau tumor suppressor gene in sporadic central nervous system hemangioblastomas. Cancer Res 54:4845\u20134847","journal-title":"Cancer Res"},{"key":"910_CR66","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1227\/00006123-198804000-00029","volume":"22","author":"EJ Kasarskis","year":"1988","unstructured":"Kasarskis EJ, Tibbs PA, Lee C (1988) Cerebellar hemangioblastoma symptomatic during pregnancy. Neurosurgery 22:770\u2013772","journal-title":"Neurosurgery"},{"key":"910_CR67","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1258\/om.2009.090018","volume":"2","author":"AP Kenyon","year":"2009","unstructured":"Kenyon AP, Haider S, Ashkan K, Nelson-Piercy C (2009) Cerebellar haemangioblastoma presenting with dizziness in pregnancy: case report and review of the literature. Obstet Med 2:164\u2013167. https:\/\/doi.org\/10.1258\/om.2009.090018","journal-title":"Obstet Med"},{"key":"910_CR68","doi-asserted-by":"publisher","first-page":"2039","DOI":"10.1056\/NEJMra0706596","volume":"358","author":"RS Kerbel","year":"2008","unstructured":"Kerbel RS (2008) Tumor angiogenesis. N Engl J Med 358:2039\u20132049. https:\/\/doi.org\/10.1056\/NEJMra0706596","journal-title":"N Engl J Med"},{"key":"910_CR69","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3858\/emm.2012.44.1.023","volume":"44","author":"KJ Kim","year":"2012","unstructured":"Kim KJ, Cho CS, Kim WU (2012) Role of placenta growth factor in cancer and inflammation. Exp Mol Med 44:10\u201319. https:\/\/doi.org\/10.3858\/emm.2012.3844.3851.3023","journal-title":"Exp Mol Med"},{"key":"910_CR70","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1097\/00008506-199801000-00007","volume":"10","author":"G Korula","year":"1998","unstructured":"Korula G, Farling P (1998) Anesthetic management for a combined Cesarean section and posterior fossa craniectomy. J Neurosurg Anesthesiol 10:30\u201333","journal-title":"J Neurosurg Anesthesiol"},{"key":"910_CR71","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1081\/PRG-120028286","volume":"23","author":"T Krauss","year":"2004","unstructured":"Krauss T, Pauer HU, Augustin HG (2004) Prospective analysis of placenta growth factor (PlGF) concentrations in the plasma of women with normal pregnancy and pregnancies complicated by preeclampsia. Hypertens Pregnancy 23:101\u2013111","journal-title":"Hypertens Pregnancy"},{"key":"910_CR72","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1055\/s-2007-996715","volume":"29","author":"H Kuhnigk","year":"1994","unstructured":"Kuhnigk H, Danhauser-Leistner I (1994) Cesarean section with subsequent craniotomy in the area of the posterior cranial fossa. Anasthesiol Intensivmed Notfallmed Schmerzther 29:184\u2013187","journal-title":"Anasthesiol Intensivmed Notfallmed Schmerzther"},{"key":"910_CR73","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1111\/j.1600-0897.1997.tb00519.x","volume":"38","author":"MJ Kupferminc","year":"1997","unstructured":"Kupferminc MJ, Daniel Y, Englender T, Baram A, Many A, Jaffa AJ, Gull I, Lessing JB (1997) Vascular endothelial growth factor is increased in patients with preeclampsia. Am J Reprod Immunol 38:302\u2013306","journal-title":"Am J Reprod Immunol"},{"key":"910_CR74","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1007\/s00415-003-0950-2","volume":"250","author":"A Kurne","year":"2003","unstructured":"Kurne A, Bakar B, Arsava EM, Tan E (2003) Pregnancy associated quadriparesis in a patient with Von-Hippel Lindau disease. J Neurol 250:234\u2013235","journal-title":"J Neurol"},{"key":"910_CR75","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1038\/sj.onc.1201545","volume":"16","author":"E Landgren","year":"1998","unstructured":"Landgren E, Schiller P, Cao Y, Claesson-Welsh L (1998) Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-gamma and migration of endothelial cells expressing Flt 1. Oncogene 16:359\u2013367","journal-title":"Oncogene"},{"key":"910_CR76","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1038\/bjc.2011.609","volume":"106","author":"U Lassen","year":"2012","unstructured":"Lassen U, Nielsen DL, Sorensen M, Winstedt L, Niskanen T, Stenberg Y, Pakola S, Stassen JM, Glazer S (2012) A phase I, dose-escalation study of TB-403, a monoclonal antibody directed against PlGF, in patients with advanced solid tumours. Br J Cancer 106:678\u2013684. https:\/\/doi.org\/10.1038\/bjc.2011.1609","journal-title":"Br J Cancer"},{"key":"910_CR77","first-page":"017","volume":"7","author":"Y Laviv","year":"2017","unstructured":"Laviv Y, Kasper BS, Kasper EM (2017) Vascular hyperpermeability as a hallmark of phacomatoses: is the etiology angiogenesis comparable with mechanisms seen in inflammatory pathways? Part I: historical observations and clinical perspectives on the etiology of increased CSF protein levels, CSF clotting, and communicating hydrocephalus: a comprehensive review. Neurosurg Rev 7:017\u20130839","journal-title":"Neurosurg Rev"},{"key":"910_CR78","first-page":"424","volume":"63","author":"S Lechowski","year":"1992","unstructured":"Lechowski S, Stypula J, Niespodzianski K, Domagala S (1992) Surgery of brain angioma (hemangioblastoma cerebelli) during the 31st week of pregnancy. Ginekol Pol 63:424\u2013427","journal-title":"Ginekol Pol"},{"key":"910_CR79","first-page":"504","volume":"58","author":"JY Lee","year":"1998","unstructured":"Lee JY, Dong SM, Park WS, Yoo NJ, Kim CS, Jang JJ, Chi JG, Zbar B, Lubensky IA, Linehan WM, Vortmeyer AO, Zhuang Z (1998) Loss of heterozygosity and somatic mutations of the VHL tumor suppressor gene in sporadic cerebellar hemangioblastomas. Cancer Res 58:504\u2013508","journal-title":"Cancer Res"},{"key":"910_CR80","doi-asserted-by":"publisher","first-page":"992","DOI":"10.1056\/NEJMoa055352","volume":"355","author":"RJ Levine","year":"2006","unstructured":"Levine RJ, Lam C, Qian C, Yu KF, Maynard SE, Sachs BP, Sibai BM, Epstein FH, Romero R, Thadhani R, Karumanchi SA (2006) Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N Engl J Med 355:992\u20131005","journal-title":"N Engl J Med"},{"key":"910_CR81","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1056\/NEJMoa031884","volume":"350","author":"RJ Levine","year":"2004","unstructured":"Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA (2004) Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 350:672\u2013683","journal-title":"N Engl J Med"},{"key":"910_CR82","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1001\/jama.293.1.77","volume":"293","author":"RJ Levine","year":"2005","unstructured":"Levine RJ, Thadhani R, Qian C, Lam C, Lim KH, Yu KF, Blink AL, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA (2005) Urinary placental growth factor and risk of preeclampsia. JAMA 293:77\u201385","journal-title":"JAMA"},{"key":"910_CR83","first-page":"363","volume":"24","author":"A Lindau","year":"1931","unstructured":"Lindau A (1931) Discussion on vascular tumours of the brain and spinal cord: Joint Discussion No. 1. Proc R Soc Med 24:363\u2013388","journal-title":"Proc R Soc Med"},{"key":"910_CR84","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1016\/j.exphem.2004.03.005","volume":"32","author":"AF List","year":"2004","unstructured":"List AF, Glinsmann-Gibson B, Stadheim C, Meuillet EJ, Bellamy W, Powis G (2004) Vascular endothelial growth factor receptor-1 and receptor-2 initiate a phosphatidylinositide 3-kinase-dependent clonogenic response in acute myeloid leukemia cells. Exp Hematol 32:526\u2013535","journal-title":"Exp Hematol"},{"key":"910_CR85","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1111\/j.1749-6632.2002.tb04870.x","volume":"979","author":"A Luttun","year":"2002","unstructured":"Luttun A, Tjwa M, Carmeliet P (2002) Placental growth factor (PlGF) and its receptor Flt-1 (VEGFR-1): novel therapeutic targets for angiogenic disorders. Ann N Y Acad Sci 979:80\u201393","journal-title":"Ann N Y Acad Sci"},{"key":"910_CR86","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1038\/nm731","volume":"8","author":"A Luttun","year":"2002","unstructured":"Luttun A, Tjwa M, Moons L, Wu Y, Angelillo-Scherrer A, Liao F, Nagy JA, Hooper A, Priller J, De Klerck B, Compernolle V, Daci E, Bohlen P, Dewerchin M, Herbert JM, Fava R, Matthys P, Carmeliet G, Collen D, Dvorak HF, Hicklin DJ, Carmeliet P (2002) Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1. Nat Med 8:831\u2013840","journal-title":"Nat Med"},{"key":"910_CR87","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1111\/j.1471-0528.1997.tb11050.x","volume":"104","author":"F Lyall","year":"1997","unstructured":"Lyall F, Greer IA, Boswell F, Fleming R (1997) Suppression of serum vascular endothelial growth factor immunoreactivity in normal pregnancy and in pre-eclampsia. Br J Obstet Gynaecol 104:223\u2013228","journal-title":"Br J Obstet Gynaecol"},{"key":"910_CR88","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1111\/j.1600-0447.1944.tb04570.x","volume":"19","author":"H M\u04e7ller","year":"1944","unstructured":"M\u04e7ller H (1944) Ophthalmic symptoms and heredity in cerebellar angioreticuloma. Acta Psychiatr Neurol 19:275\u2013292","journal-title":"Acta Psychiatr Neurol"},{"key":"910_CR89","doi-asserted-by":"publisher","first-page":"9267","DOI":"10.1073\/pnas.88.20.9267","volume":"88","author":"D Maglione","year":"1991","unstructured":"Maglione D, Guerriero V, Viglietto G, Delli-Bovi P, Persico MG (1991) Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor. Proc Natl Acad Sci U S A 88:9267\u20139271","journal-title":"Proc Natl Acad Sci U S A"},{"key":"910_CR90","first-page":"4953","volume":"23","author":"K Matsumoto","year":"2003","unstructured":"Matsumoto K, Suzuki K, Koike H, Okamura K, Tsuchiya K, Uchida T, Takezawa Y, Kobayashi M, Yamanaka H (2003) Prognostic significance of plasma placental growth factor levels in renal cell cancer: an association with clinical characteristics and vascular endothelial growth factor levels. Anticancer Res 23:4953\u20134958","journal-title":"Anticancer Res"},{"key":"910_CR91","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1172\/JCI17189","volume":"111","author":"SE Maynard","year":"2003","unstructured":"Maynard SE, Min JY, Merchan J, Lim KH, Li J, Mondal S, Libermann TA, Morgan JP, Sellke FW, Stillman IE, Epstein FH, Sukhatme VP, Karumanchi SA (2003) Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest 111:649\u2013658","journal-title":"J Clin Invest"},{"key":"910_CR92","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1006\/bbrc.1993.1885","volume":"194","author":"K Morii","year":"1993","unstructured":"Morii K, Tanaka R, Washiyama K, Kumanishi T, Kuwano R (1993) Expression of vascular endothelial growth factor in capillary hemangioblastoma. Biochem Biophys Res Commun 194:749\u2013755","journal-title":"Biochem Biophys Res Commun"},{"key":"910_CR93","doi-asserted-by":"publisher","first-page":"8211","DOI":"10.1158\/0008-5472.CAN-10-0202","volume":"70","author":"M Muramatsu","year":"2010","unstructured":"Muramatsu M, Yamamoto S, Osawa T, Shibuya M (2010) Vascular endothelial growth factor receptor-1 signaling promotes mobilization of macrophage lineage cells from bone marrow and stimulates solid tumor growth. Cancer Res 70:8211\u20138221. https:\/\/doi.org\/10.1158\/0008-5472.CAN-8210-0202","journal-title":"Cancer Res"},{"key":"910_CR94","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/s10456-008-9099-z","volume":"11","author":"JA Nagy","year":"2008","unstructured":"Nagy JA, Benjamin L, Zeng H, Dvorak AM, Dvorak HF (2008) Vascular permeability, vascular hyperpermeability and angiogenesis. Angiogenesis 11:109\u2013119. https:\/\/doi.org\/10.1007\/s10456-10008-19099-z","journal-title":"Angiogenesis"},{"key":"910_CR95","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1080\/02688699845168","volume":"12","author":"K Naidoo","year":"1998","unstructured":"Naidoo K, Bhigjee AI (1998) Multiple cerebellar haemangioblastomas symptomatic during pregnancy. Br J Neurosurg 12:281\u2013284","journal-title":"Br J Neurosurg"},{"key":"910_CR96","first-page":"662","volume":"40","author":"L Nathan","year":"1995","unstructured":"Nathan L, Satin AJ, Twickler DM (1995) Cerebellar hemangioblastoma complicating pregnancy. A case report. J Reprod Med 40:662\u2013664","journal-title":"J Reprod Med"},{"key":"910_CR97","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.blre.2016.08.004","volume":"31","author":"LF Newell","year":"2017","unstructured":"Newell LF, Holtan SG (2017) Placental growth factor: what hematologists need to know. Blood Rev 31:57\u201362. https:\/\/doi.org\/10.1016\/j.blre.2016.1008.1004","journal-title":"Blood Rev"},{"key":"910_CR98","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1023\/A:1006198422718","volume":"40","author":"M Nomura","year":"1998","unstructured":"Nomura M, Yamagishi S, Harada S, Yamashima T, Yamashita J, Yamamoto H (1998) Placenta growth factor (PlGF) mRNA expression in brain tumors. J Neuro-Oncol 40:123\u2013130","journal-title":"J Neuro-Oncol"},{"key":"910_CR99","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.jdermsci.2005.08.008","volume":"41","author":"T Odorisio","year":"2006","unstructured":"Odorisio T, Cianfarani F, Failla CM, Zambruno G (2006) The placenta growth factor in skin angiogenesis. J Dermatol Sci 41:11\u201319","journal-title":"J Dermatol Sci"},{"key":"910_CR100","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1016\/0029-7844(94)00304-V","volume":"85","author":"KK Ogasawara","year":"1995","unstructured":"Ogasawara KK, Ogasawara EM, Hirata G (1995) Pregnancy complicated by von Hippel-Lindau disease. Obstet Gynecol 85:829\u2013831","journal-title":"Obstet Gynecol"},{"key":"910_CR101","first-page":"1752","volume":"6","author":"AI Omar","year":"2012","unstructured":"Omar AI (2012) Bevacizumab for the treatment of surgically unresectable cervical cord hemangioblastoma: a case report. J Med Case Rep 6:1752\u20131947","journal-title":"J Med Case Rep"},{"key":"910_CR102","doi-asserted-by":"publisher","first-page":"254","DOI":"10.3171\/SPI-07\/08\/254","volume":"7","author":"M Ortega-Martinez","year":"2007","unstructured":"Ortega-Martinez M, Cabezudo JM, Fernandez-Portales I, Pineda-Palomo M, Rodriguez-Sanchez JA, Bernal-Garcia LM (2007) Multiple filum terminale hemangioblastomas symptomatic during pregnancy. Case report. J Neurosurg Spine 7:254\u2013258","journal-title":"J Neurosurg Spine"},{"key":"910_CR103","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/S0002-9394(99)00199-3","volume":"128","author":"IS Othmane","year":"1999","unstructured":"Othmane IS, Shields C, Singh A, Shields J, Goldman W (1999) Postpartum cerebellar herniation in von Hippel-Lindau syndrome. Am J Ophthalmol 128:387\u2013389","journal-title":"Am J Ophthalmol"},{"key":"910_CR104","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1111\/j.1600-0412.2011.01186.x","volume":"90","author":"M Palm","year":"2011","unstructured":"Palm M, Basu S, Larsson A, Wernroth L, Akerud H, Axelsson O (2011) A longitudinal study of plasma levels of soluble fms-like tyrosine kinase 1 (sFlt1), placental growth factor (PlGF), sFlt1: PlGF ratio and vascular endothelial growth factor (VEGF-A) in normal pregnancy. Acta Obstet Gynecol Scand 90:1244\u20131251. https:\/\/doi.org\/10.1111\/j.1600-0412.2011.01186.x","journal-title":"Acta Obstet Gynecol Scand"},{"key":"910_CR105","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/BF01401877","volume":"27","author":"JJ Palmer","year":"1972","unstructured":"Palmer JJ (1972) Haemangioblastomas. A review of 81 cases. Acta Neurochir 27:125\u2013148","journal-title":"Acta Neurochir"},{"key":"910_CR106","doi-asserted-by":"publisher","first-page":"e60","DOI":"10.1371\/journal.pmed.0040060","volume":"4","author":"DM Park","year":"2007","unstructured":"Park DM, Zhuang Z, Chen L, Szerlip N, Maric I, Li J, Sohn T, Kim SH, Lubensky IA, Vortmeyer AO, Rodgers GP, Oldfield EH, Lonser RR (2007) von Hippel-Lindau disease-associated hemangioblastomas are derived from embryologic multipotent cells. PLoS Med 4:e60","journal-title":"PLoS Med"},{"key":"910_CR107","doi-asserted-by":"crossref","first-page":"25646","DOI":"10.1016\/S0021-9258(18)47298-5","volume":"269","author":"JE Park","year":"1994","unstructured":"Park JE, Chen HH, Winer J, Houck KA, Ferrara N (1994) Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1\/KDR. J Biol Chem 269:25646\u201325654","journal-title":"J Biol Chem"},{"key":"910_CR108","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1016\/j.ejogrb.2012.08.002","volume":"165","author":"A Pereda Rios","year":"2012","unstructured":"Pereda Rios A, Pintado Recarte P, De Leon-Luis J, Fernandez-Garcia P, Iza B, Salinero Paniagua E, Aguaron de la Cruz A, Ortiz Quintana L (2012) Cerebellar hemangioblastoma as the cause of maternal obstructive hydrocephalus during the third trimester. Eur J Obstet Gynecol Reprod Biol 165:370\u2013372","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"910_CR109","doi-asserted-by":"publisher","first-page":"1506","DOI":"10.1182\/blood-2002-11-3422","volume":"102","author":"N Perelman","year":"2003","unstructured":"Perelman N, Selvaraj SK, Batra S, Luck LR, Erdreich-Epstein A, Coates TD, Kalra VK, Malik P (2003) Placenta growth factor activates monocytes and correlates with sickle cell disease severity. Blood 102:1506\u20131514","journal-title":"Blood"},{"key":"910_CR110","first-page":"31","volume":"237","author":"MG Persico","year":"1999","unstructured":"Persico MG, Vincenti V, DiPalma T (1999) Structure, expression and receptor-binding properties of placenta growth factor (PlGF). Curr Top Microbiol Immunol 237:31\u201340","journal-title":"Curr Top Microbiol Immunol"},{"key":"910_CR111","doi-asserted-by":"publisher","unstructured":"Pierscianek D, Wolf S, Keyvani K, El Hindy N, Stein KP, Sandalcioglu IE, Sure U, Mueller O, Zhu Y (2017) Study of angiogenic signaling pathways in hemangioblastoma. Neuropathology 37:3\u201311. https:\/\/doi.org\/10.1111\/neup.12316. Epub 12016 Jul 12317","DOI":"10.1111\/neup.12316."},{"key":"910_CR112","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1111\/j.1749-6632.2003.tb03232.x","volume":"996","author":"S Rafii","year":"2003","unstructured":"Rafii S, Avecilla S, Shmelkov S, Shido K, Tejada R, Moore MA, Heissig B, Hattori K (2003) Angiogenic factors reconstitute hematopoiesis by recruiting stem cells from bone marrow microenvironment. Ann N Y Acad Sci 996:49\u201360","journal-title":"Ann N Y Acad Sci"},{"key":"910_CR113","doi-asserted-by":"publisher","unstructured":"Rehman T, Ali R, Yonas H (2009) Cerebellar haemangioblastoma: temporising treatment in a high risk pregnancy. BMJ Case Rep. https:\/\/doi.org\/10.1136\/bcr.01.2009.1413","DOI":"10.1136\/bcr.01.2009.1413"},{"key":"910_CR114","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1038\/386671a0","volume":"386","author":"W Risau","year":"1997","unstructured":"Risau W (1997) Mechanisms of angiogenesis. Nature 386:671\u2013674","journal-title":"Nature"},{"key":"910_CR115","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1111\/j.1600-0404.1965.tb04307.x","volume":"41","author":"RG Robinson","year":"1966","unstructured":"Robinson RG (1966) Aspects of the natural history of cerebellar haemangioblastomas. Acta Neurol Scand 41:372\u2013380","journal-title":"Acta Neurol Scand"},{"key":"910_CR116","doi-asserted-by":"publisher","unstructured":"Rolny C, Mazzone M, Tugues S, Laoui D, Johansson I, Coulon C, Squadrito ML, Segura I, Li X, Knevels E, Costa S, Vinckier S, Dresselaer T, Akerud P, De Mol M, Salomaki H, Phillipson M, Wyns S, Larsson E, Buysschaert I, Botling J, Himmelreich U, Van Ginderachter JA, De Palma M, Dewerchin M, Claesson-Welsh L, Carmeliet P (2011) HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF. Cancer Cell 19:31\u201344. https:\/\/doi.org\/10.1016\/j.ccr.2010.1011.1009. Epub 2011 Jan 1016","DOI":"10.1016\/j.ccr.2010.1011.1009."},{"key":"910_CR117","first-page":"37","volume":"53","author":"K Romansky","year":"1992","unstructured":"Romansky K, Arnaudova V, Nachev S (1992) Hemangioblastoma during pregnancy. Case report. Zentralbl Neurochir 53:37\u201339","journal-title":"Zentralbl Neurochir"},{"key":"910_CR118","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1080\/14767050701830480","volume":"21","author":"R Romero","year":"2008","unstructured":"Romero R, Nien JK, Espinoza J, Todem D, Fu W, Chung H, Kusanovic JP, Gotsch F, Erez O, Mazaki-Tovi S, Gomez R, Edwin S, Chaiworapongsa T, Levine RJ, Karumanchi SA (2008) A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate. J Matern Fetal Neonatal Med 21:9\u201323. https:\/\/doi.org\/10.1080\/14767050701830480","journal-title":"J Matern Fetal Neonatal Med"},{"key":"910_CR119","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1089\/152581602753448496","volume":"11","author":"FR Sabin","year":"2002","unstructured":"Sabin FR (2002) Preliminary note on the differentiation of angioblasts and the method by which they produce blood-vessels, blood-plasma and red blood-cells as seen in the living chick. 1917. J Hematother Stem Cell Res 11:5\u20137","journal-title":"J Hematother Stem Cell Res"},{"key":"910_CR120","doi-asserted-by":"publisher","first-page":"11432","DOI":"10.1158\/0008-5472.CAN-06-1867","volume":"66","author":"A Saccani","year":"2006","unstructured":"Saccani A, Schioppa T, Porta C, Biswas SK, Nebuloni M, Vago L, Bottazzi B, Colombo MP, Mantovani A, Sica A (2006) p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res 66:11432\u201311440","journal-title":"Cancer Res"},{"key":"910_CR121","first-page":"25","volume":"2","author":"GD Satyarthee","year":"2016","unstructured":"Satyarthee GD, Kumar S (2016) Cerebellar hemangioblastoma symptomatic during pregnancy: a short review. Am J Clin Neurol Neurosurg 2:25\u201328","journal-title":"Am J Clin Neurol Neurosurg"},{"key":"910_CR122","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1016\/S0002-9378(16)36150-6","volume":"82","author":"G Scarcella","year":"1961","unstructured":"Scarcella G, Allen MB Jr, Andy OJ (1961) Vascular lesions of the posterior fossa during pregnancy. Am J Obstet Gynecol 82:836\u2013840","journal-title":"Am J Obstet Gynecol"},{"key":"910_CR123","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1016\/j.ccr.2011.05.007","volume":"19","author":"T Schmidt","year":"2011","unstructured":"Schmidt T, Kharabi Masouleh B, Loges S, Cauwenberghs S, Fraisl P, Maes C, Jonckx B, De Keersmaecker K, Kleppe M, Tjwa M, Schenk T, Vinckier S, Fragoso R, De Mol M, Beel K, Dias S, Verfaillie C, Clark RE, Brummendorf TH, Vandenberghe P, Rafii S, Holyoake T, Hochhaus A, Cools J, Karin M, Carmeliet G, Dewerchin M, Carmeliet P (2011) Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia. Cancer Cell 19:740\u2013753. https:\/\/doi.org\/10.1016\/j.ccr.2011.1005.1007","journal-title":"Cancer Cell"},{"key":"910_CR124","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1096\/fj.11-191916","volume":"26","author":"MP Schreurs","year":"2012","unstructured":"Schreurs MP, Houston EM, May V, Cipolla MJ (2012) The adaptation of the blood-brain barrier to vascular endothelial growth factor and placental growth factor during pregnancy. FASEB J 26:355\u2013362. https:\/\/doi.org\/10.1096\/fj.1011-191916","journal-title":"FASEB J"},{"key":"910_CR125","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1182\/blood-2002-11-3423","volume":"102","author":"SK Selvaraj","year":"2003","unstructured":"Selvaraj SK, Giri RK, Perelman N, Johnson C, Malik P, Kalra VK (2003) Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor. Blood 102:1515\u20131524","journal-title":"Blood"},{"key":"910_CR126","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1126\/science.6823562","volume":"219","author":"DR Senger","year":"1983","unstructured":"Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF (1983) Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219:983\u2013985","journal-title":"Science"},{"key":"910_CR127","doi-asserted-by":"publisher","first-page":"014","DOI":"10.1186\/s40478-014-0167-x","volume":"2","author":"GM Shankar","year":"2014","unstructured":"Shankar GM, Taylor-Weiner A, Lelic N, Jones RT, Kim JC, Francis JM, Abedalthagafi M, Borges LF, Coumans JV, Curry WT, Nahed BV, Shin JH, Paek SH, Park SH, Stewart C, Lawrence MS, Cibulskis K, Thorner AR, Van Hummelen P, Stemmer-Rachamimov AO, Batchelor TT, Carter SL, Hoang MP, Santagata S, Louis DN, Barker FG, Meyerson M, Getz G, Brastianos PK, Cahill DP (2014) Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathol Commun 2:014\u20130167","journal-title":"Acta Neuropathol Commun"},{"key":"910_CR128","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1046\/j.1365-2362.1996.830605.x","volume":"26","author":"AM Sharkey","year":"1996","unstructured":"Sharkey AM, Cooper JC, Balmforth JR, McLaren J, Clark DE, Charnock-Jones DS, Morris NH, Smith SK (1996) Maternal plasma levels of vascular endothelial growth factor in normotensive pregnancies and in pregnancies complicated by pre-eclampsia. Eur J Clin Investig 26:1182\u20131185","journal-title":"Eur J Clin Investig"},{"key":"910_CR129","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1016\/j.cell.2013.01.036","volume":"152","author":"M Snuderl","year":"2013","unstructured":"Snuderl M, Batista A, Kirkpatrick ND, Ruiz de Almodovar C, Riedemann L, Walsh EC, Anolik R, Huang Y, Martin JD, Kamoun W, Knevels E, Schmidt T, Farrar CT, Vakoc BJ, Mohan N, Chung E, Roberge S, Peterson T, Bais C, Zhelyazkova BH, Yip S, Hasselblatt M, Rossig C, Niemeyer E, Ferrara N, Klagsbrun M, Duda DG, Fukumura D, Xu L, Carmeliet P, Jain RK (2013) Targeting placental growth factor\/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell 152:1065\u20131076. https:\/\/doi.org\/10.1016\/j.cell.2013.1001.1036","journal-title":"Cell"},{"key":"910_CR130","doi-asserted-by":"publisher","first-page":"751","DOI":"10.3171\/jns.1960.17.4.0751","volume":"17","author":"AA Stein","year":"1960","unstructured":"Stein AA, Schilp AO, Whitfield RD (1960) The histogenesis of hemangioblastoma of the brain. A review of twenty-one cases. J Neurosurg 17:751\u2013761","journal-title":"J Neurosurg"},{"key":"910_CR131","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1006\/bbrc.1999.0465","volume":"257","author":"A Takahashi","year":"1999","unstructured":"Takahashi A, Sasaki H, Kim SJ, Kakizoe T, Miyao N, Sugimura T, Terada M, Tsukamoto T (1999) Identification of receptor genes in renal cell carcinoma associated with angiogenesis by differential hybridization technique. Biochem Biophys Res Commun 257:855\u2013859","journal-title":"Biochem Biophys Res Commun"},{"key":"910_CR132","first-page":"4233","volume":"54","author":"A Takahashi","year":"1994","unstructured":"Takahashi A, Sasaki H, Kim SJ, Tobisu K, Kakizoe T, Tsukamoto T, Kumamoto Y, Sugimura T, Terada M (1994) Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis. Cancer Res 54:4233\u20134237","journal-title":"Cancer Res"},{"key":"910_CR133","first-page":"4","volume":"3179670","author":"V Tandon","year":"2017","unstructured":"Tandon V, Hiwale S, Amle D, Nagaria T, Patra PK (2017) Assessment of serum vascular endothelial growth factor levels in pregnancy-induced hypertension patients. J Pregnancy 3179670:4","journal-title":"J Pregnancy"},{"key":"910_CR134","doi-asserted-by":"publisher","first-page":"1804","DOI":"10.1158\/0008-5472.CAN-09-2609","volume":"70","author":"V Tarallo","year":"2010","unstructured":"Tarallo V, Vesci L, Capasso O, Esposito MT, Riccioni T, Pastore L, Orlandi A, Pisano C, De Falco S (2010) A placental growth factor variant unable to recognize vascular endothelial growth factor (VEGF) receptor-1 inhibits VEGF-dependent tumor angiogenesis via heterodimerization. Cancer Res 70:1804\u20131813. https:\/\/doi.org\/10.1158\/0008-5472.CAN-1809-2609","journal-title":"Cancer Res"},{"key":"910_CR135","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.ajog.2015.02.013","volume":"213","author":"AR Terry","year":"2015","unstructured":"Terry AR, Merker VL, Barker FG 2nd, Leffert L, Bateman BT, Souter I, Plotkin SR (2015) Pregnancy complications in women with rare tumor suppressor syndromes affecting central and peripheral nervous system. Am J Obstet Gynecol 213:108\u2013109. https:\/\/doi.org\/10.1016\/j.ajog.2015.1002.1013","journal-title":"Am J Obstet Gynecol"},{"key":"910_CR136","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1111\/j.1600-0897.1992.tb00746.x","volume":"27","author":"RJ Torry","year":"1992","unstructured":"Torry RJ, Rongish BJ (1992) Angiogenesis in the uterus: potential regulation and relation to tumor angiogenesis. Am J Reprod Immunol 27:171\u2013179","journal-title":"Am J Reprod Immunol"},{"key":"910_CR137","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.cell.2010.02.039","volume":"141","author":"S Veire Van de","year":"2010","unstructured":"Van de Veire S, Stalmans I, Heindryckx F, Oura H, Tijeras-Raballand A, Schmidt T, Loges S, Albrecht I, Jonckx B, Vinckier S, Van Steenkiste C, Tugues S, Rolny C, De Mol M, Dettori D, Hainaud P, Coenegrachts L, Contreres JO, Van Bergen T, Cuervo H, Xiao WH, Le Henaff C, Buysschaert I, Kharabi Masouleh B, Geerts A, Schomber T, Bonnin P, Lambert V, Haustraete J, Zacchigna S, Rakic JM, Jimenez W, Noel A, Giacca M, Colle I, Foidart JM, Tobelem G, Morales-Ruiz M, Vilar J, Maxwell P, Vinores SA, Carmeliet G, Dewerchin M, Claesson-Welsh L, Dupuy E, Van Vlierberghe H, Christofori G, Mazzone M, Detmar M, Collen D, Carmeliet P (2010) Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease. Cell 141:178\u2013190. https:\/\/doi.org\/10.1016\/j.cell.2010.1002.1039","journal-title":"Cell"},{"key":"910_CR138","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/0090-3019(84)90421-X","volume":"21","author":"J Vaquero","year":"1984","unstructured":"Vaquero J, Martinez R (1984) Progesterone receptor proteins in cerebellar hemangioblastoma. Surg Neurol 21:99","journal-title":"Surg Neurol"},{"key":"910_CR139","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1002\/ana.20090","volume":"55","author":"AO Vortmeyer","year":"2004","unstructured":"Vortmeyer AO, Yuan Q, Lee YS, Zhuang Z, Oldfield EH (2004) Developmental effects of von Hippel-Lindau gene deficiency. Ann Neurol 55:721\u2013728","journal-title":"Ann Neurol"},{"key":"910_CR140","doi-asserted-by":"publisher","first-page":"82","DOI":"10.3171\/jns.2003.98.1.0082","volume":"98","author":"JE Wanebo","year":"2003","unstructured":"Wanebo JE, Lonser RR, Glenn GM, Oldfield EH (2003) The natural history of hemangioblastomas of the central nervous system in patients with von Hippel-Lindau disease. J Neurosurg 98:82\u201394","journal-title":"J Neurosurg"},{"key":"910_CR141","doi-asserted-by":"publisher","first-page":"140.e141","DOI":"10.1016\/j.ajog.2012.05.003","volume":"207","author":"S Weed","year":"2012","unstructured":"Weed S, Bastek JA, Anton L, Elovitz MA, Parry S, Srinivas SK (2012) Examining the correlation between placental and serum placenta growth factor in preeclampsia. Am J Obstet Gynecol 207:140.e141\u2013140.e146. https:\/\/doi.org\/10.1016\/j.ajog.2012.1005.1003","journal-title":"Am J Obstet Gynecol"},{"key":"910_CR142","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1136\/gut.2004.050831","volume":"54","author":"SC Wei","year":"2005","unstructured":"Wei SC, Tsao PN, Yu SC, Shun CT, Tsai-Wu JJ, Wu CH, Su YN, Hsieh FJ, Wong JM (2005) Placenta growth factor expression is correlated with survival of patients with colorectal cancer. Gut 54:666\u2013672","journal-title":"Gut"},{"key":"910_CR143","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1097\/01.AOG.0000264552.85436.a1","volume":"109","author":"AK Wikstrom","year":"2007","unstructured":"Wikstrom AK, Larsson A, Eriksson UJ, Nash P, Norden-Lindeberg S, Olovsson M (2007) Placental growth factor and soluble FMS-like tyrosine kinase-1 in early-onset and late-onset preeclampsia. Obstet Gynecol 109:1368\u20131374","journal-title":"Obstet Gynecol"},{"key":"910_CR144","first-page":"1358","volume":"55","author":"S Wizigmann-Voos","year":"1995","unstructured":"Wizigmann-Voos S, Breier G, Risau W, Plate KH (1995) Up-regulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas. Cancer Res 55:1358\u20131364","journal-title":"Cancer Res"},{"key":"910_CR145","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1002\/ijc.21865","volume":"119","author":"Y Wu","year":"2006","unstructured":"Wu Y, Hooper AT, Zhong Z, Witte L, Bohlen P, Rafii S, Hicklin DJ (2006) The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma. Int J Cancer 119:1519\u20131529","journal-title":"Int J Cancer"},{"key":"910_CR146","doi-asserted-by":"publisher","first-page":"2623","DOI":"10.1084\/jem.20080398","volume":"205","author":"K Yano","year":"2008","unstructured":"Yano K, Okada Y, Beldi G, Shih SC, Bodyak N, Okada H, Kang PM, Luscinskas W, Robson SC, Carmeliet P, Karumanchi SA, Aird WC (2008) Elevated levels of placental growth factor represent an adaptive host response in sepsis. J Exp Med 205:2623\u20132631. https:\/\/doi.org\/10.1084\/jem.20080398","journal-title":"J Exp Med"},{"key":"910_CR147","doi-asserted-by":"publisher","first-page":"11590","DOI":"10.1073\/pnas.1109029108","volume":"108","author":"J Yao","year":"2011","unstructured":"Yao J, Wu X, Zhuang G, Kasman IM, Vogt T, Phan V, Shibuya M, Ferrara N, Bais C (2011) Expression of a functional VEGFR-1 in tumor cells is a major determinant of anti-PlGF antibodies efficacy. Proc Natl Acad Sci U S A 108:11590\u201311595. 10.11073\/pnas.1109029108","journal-title":"Proc Natl Acad Sci U S A"},{"key":"910_CR148","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1016\/j.febslet.2005.01.017","volume":"579","author":"YG Yao","year":"2005","unstructured":"Yao YG, Yang HS, Cao Z, Danielsson J, Duh EJ (2005) Upregulation of placental growth factor by vascular endothelial growth factor via a post-transcriptional mechanism. FEBS Lett 579:1227\u20131234","journal-title":"FEBS Lett"},{"key":"910_CR149","doi-asserted-by":"publisher","first-page":"818","DOI":"10.3171\/2012.7.JNS12367","volume":"117","author":"DY Ye","year":"2012","unstructured":"Ye DY, Bakhtian KD, Asthagiri AR, Lonser RR (2012) Effect of pregnancy on hemangioblastoma development and progression in von Hippel-Lindau disease. J Neurosurg 117:818\u2013824","journal-title":"J Neurosurg"},{"key":"910_CR150","doi-asserted-by":"publisher","first-page":"35172","DOI":"10.1074\/jbc.274.49.35172","volume":"274","author":"H Yonekura","year":"1999","unstructured":"Yonekura H, Sakurai S, Liu X, Migita H, Wang H, Yamagishi S, Nomura M, Abedin MJ, Unoki H, Yamamoto Y, Yamamoto H (1999) Placenta growth factor and vascular endothelial growth factor B and C expression in microvascular endothelial cells and pericytes. Implication in autocrine and paracrine regulation of angiogenesis. J Biol Chem 274:35172\u201335178","journal-title":"J Biol Chem"},{"key":"910_CR151","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/1477-7819-3-68","volume":"3","author":"L Zhang","year":"2005","unstructured":"Zhang L, Chen J, Ke Y, Mansel RE, Jiang WG (2005) Expression of Placenta growth factor (PlGF) in non-small cell lung cancer (NSCLC) and the clinical and prognostic significance. World J Surg Oncol 3:68","journal-title":"World J Surg Oncol"},{"key":"910_CR152","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1016\/j.bbrc.2016.01.073","volume":"470","author":"Y Zhou","year":"2016","unstructured":"Zhou Y, Tu C, Zhao Y, Liu H, Zhang S (2016) Placental growth factor enhances angiogenesis in human intestinal microvascular endothelial cells via PI3K\/Akt pathway: Potential implications of inflammation bowel disease. Biochem Biophys Res Commun 470:967\u2013974. https:\/\/doi.org\/10.1016\/j.bbrc.2016.1001.1073","journal-title":"Biochem Biophys Res Commun"},{"key":"910_CR153","doi-asserted-by":"crossref","unstructured":"Zhuang Z, Frerich JM, Huntoon K, Yang C, Merrill MJ, Abdullaev Z, Pack SD, Shively SB, Stamp G, Lonser RR (2014) Tumor derived vasculogenesis in von Hippel-Lindau disease-associated tumors. Sci Rep 4:4102","DOI":"10.1038\/srep04102"},{"key":"910_CR154","first-page":"517","volume":"76","author":"M Ziche","year":"1997","unstructured":"Ziche M, Maglione D, Ribatti D, Morbidelli L, Lago CT, Battisti M, Paoletti I, Barra A, Tucci M, Parise G, Vincenti V, Granger HJ, Viglietto G, Persico MG (1997) Placenta growth factor-1 is chemotactic, mitogenic, and angiogenic. Lab Investig 76:517\u2013531","journal-title":"Lab Investig"},{"key":"910_CR155","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1007\/s00701-007-1127-z","volume":"149","author":"G Zilidis","year":"2007","unstructured":"Zilidis G, Cadoux-Hudson TA (2007) Recurrent dural based cystic cerebellar haemangioblastoma in a patient with von Hippel-Lindau disease. Acta Neurochir 149:433\u2013436","journal-title":"Acta Neurochir"},{"key":"910_CR156","doi-asserted-by":"publisher","first-page":"S10","DOI":"10.1016\/S0301-2115(03)00168-4","volume":"22","author":"M Zygmunt","year":"2003","unstructured":"Zygmunt M, Herr F, Munstedt K, Lang U, Liang OD (2003) Angiogenesis and vasculogenesis in pregnancy. Eur J Obstet Gynecol Reprod Biol 22:S10\u2013S18","journal-title":"Eur J Obstet Gynecol Reprod Biol"}],"container-title":["Neurosurgical Review"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-017-0910-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10143-017-0910-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-017-0910-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T14:32:29Z","timestamp":1659623549000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10143-017-0910-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,13]]},"references-count":156,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["910"],"URL":"https:\/\/doi.org\/10.1007\/s10143-017-0910-4","relation":{},"ISSN":["0344-5607","1437-2320"],"issn-type":[{"value":"0344-5607","type":"print"},{"value":"1437-2320","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,13]]},"assertion":[{"value":"3 July 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 September 2017","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 September 2017","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 October 2017","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee of Beth Israel Deaconess Medical Center and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}