{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:59:27Z","timestamp":1777381167243,"version":"3.51.4"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T00:00:00Z","timestamp":1619049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T00:00:00Z","timestamp":1619049600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurosurg Rev"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1007\/s10143-021-01547-9","type":"journal-article","created":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T14:02:57Z","timestamp":1619100177000},"page":"429-437","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Closure of skull base defects after endoscopic endonasal transsphenoidal surgery: the role of the local sphenoid mucosal flap for low flow leaks"],"prefix":"10.1007","volume":"45","author":[{"given":"Mendel","family":"Castle-Kirszbaum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi Yuen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brent","family":"Uren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben","family":"Dixon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Rimmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"King","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi Chen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony","family":"Goldschlager","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,4,22]]},"reference":[{"key":"1547_CR1","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/j.otohns.2007.01.024","volume":"136","author":"JP Browne","year":"2007","unstructured":"Browne JP, Hopkins C, Slack R, Cano SJ (2007) The Sino-Nasal Outcome Test (SNOT): can we make it more clinically meaningful? Otolaryngol Head Neck Surg 136:736\u2013741. https:\/\/doi.org\/10.1016\/j.otohns.2007.01.024","journal-title":"Otolaryngol Head Neck Surg"},{"key":"1547_CR2","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1097\/01.mlg.0000198338.05826.18","volume":"116","author":"JP Browne","year":"2006","unstructured":"Browne JP, Hopkins C, Slack R, Topham J, Reeves B, Lund V, Brown P, Copley L, van der Meulen J (2006) Health-related quality of life after polypectomy with and without additional surgery. Laryngoscope 116:297\u2013302. https:\/\/doi.org\/10.1097\/01.mlg.0000198338.05826.18","journal-title":"Laryngoscope"},{"key":"1547_CR3","doi-asserted-by":"publisher","unstructured":"Cappabianca P, Cavallo LM, Divitiis E de (2004) Endoscopic endonasal transsphenoidal surgery. Neurosurgery 55:933\u201340-discussion 940\u20131. https:\/\/doi.org\/10.1227\/01.neu.0000137330.02549.0d","DOI":"10.1227\/01.neu.0000137330.02549.0d"},{"key":"1547_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2020.01.072","author":"M Castle-Kirszbaum","year":"2020","unstructured":"Castle-Kirszbaum M, Wang YY, King J, Uren B, Dixon B, Zhao YC, Lim K-Z, Goldschlager T (2020) Patient wellbeing and quality of life after nasoseptal flap closure for endoscopic skull base reconstruction. J Clin Neurosci Off J Neurosurg Soc Australas. https:\/\/doi.org\/10.1016\/j.jocn.2020.01.072","journal-title":"J Clin Neurosci Off J Neurosurg Soc Australas"},{"key":"1547_CR5","doi-asserted-by":"publisher","first-page":"861","DOI":"10.3171\/2017.11.JNS172141","volume":"130","author":"A Conger","year":"2018","unstructured":"Conger A, Zhao F, Wang X, Eisenberg A, Griffiths C, Esposito F, Carrau RL, Barkhoudarian G, Kelly DF (2018) Evolution of the graded repair of CSF leaks and skull base defects in endonasal endoscopic tumor surgery: trends in repair failure and meningitis rates in 509 patients. J Neurosurg 130:861\u2013875. https:\/\/doi.org\/10.3171\/2017.11.JNS172141","journal-title":"J Neurosurg"},{"key":"1547_CR6","doi-asserted-by":"crossref","unstructured":"Esposito F, Dusick JR, Fatemi N, Kelly DF (2007) Graded repair of cranial base defects and cerebrospinal fluid leaks in transsphenoidal surgery. Oper Neurosurg 60:295\u2013303 discussion 303\u20134","DOI":"10.1227\/01.NEU.0000255354.64077.66"},{"key":"1547_CR7","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1080\/02688690310001627803","volume":"17","author":"A Goel","year":"2003","unstructured":"Goel A, Muzumdar DP (2003) Reconstruction of the sella floor using vascularized pedicled mucosal flap. Br J Neurosurg 17:553\u2013555. https:\/\/doi.org\/10.1080\/02688690310001627803","journal-title":"Br J Neurosurg"},{"key":"1547_CR8","doi-asserted-by":"publisher","first-page":"1882","DOI":"10.1097\/01.mlg.0000234933.37779.e4","volume":"116","author":"G Hadad","year":"2006","unstructured":"Hadad G, Bassagasteguy L, Carrau RL, Mataza JC, Kassam A, Snyderman CH, Mintz A (2006) A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap. Laryngoscope 116:1882\u20131886. https:\/\/doi.org\/10.1097\/01.mlg.0000234933.37779.e4","journal-title":"Laryngoscope"},{"key":"1547_CR9","doi-asserted-by":"publisher","first-page":"1887","DOI":"10.1016\/j.wneu.2015.08.025","volume":"84","author":"T Hara","year":"2015","unstructured":"Hara T, Akutsu H, Yamamoto T, Tanaka S, Takano S, Ishikawa E, Matsuda M, Matsumura A (2015) Cranial Base repair using suturing technique combined with a mucosal flap for cerebrospinal fluid leakage during endoscopic endonasal surgery. World Neurosurg 84:1887\u20131893. https:\/\/doi.org\/10.1016\/j.wneu.2015.08.025","journal-title":"World Neurosurg"},{"key":"1547_CR10","first-page":"261","volume":"15","author":"J Hardy","year":"1976","unstructured":"Hardy J, Vezina JL (1976) Transsphenoidal neurosurgery of intracranial neoplasm. Adv Neurol 15:261\u2013273","journal-title":"Adv Neurol"},{"key":"1547_CR11","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1002\/lary.22475","volume":"122","author":"RJ Harvey","year":"2012","unstructured":"Harvey RJ, Parmar P, Sacks R, Zanation AM (2012) Endoscopic skull base reconstruction of large dural defects: a systematic review of published evidence. Laryngoscope 122:452\u2013459. https:\/\/doi.org\/10.1002\/lary.22475","journal-title":"Laryngoscope"},{"key":"1547_CR12","doi-asserted-by":"publisher","first-page":"516","DOI":"10.2500\/ajr.2008.22.3223","volume":"22","author":"RJ Harvey","year":"2008","unstructured":"Harvey RJ, Smith JE, Wise SK, Patel SJ, Frankel BM, Schlosser RJ (2008) Intracranial complications before and after endoscopic skull base reconstruction. Am J Rhinol 22:516\u2013521. https:\/\/doi.org\/10.2500\/ajr.2008.22.3223","journal-title":"Am J Rhinol"},{"key":"1547_CR13","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.1097\/00005537-200007000-00019","volume":"110","author":"HM Hegazy","year":"2000","unstructured":"Hegazy HM, Carrau RL, Snyderman CH, Kassam A, Zweig J (2000) Transnasal endoscopic repair of cerebrospinal fluid rhinorrhea: a meta-analysis. Laryngoscope 110:1166\u20131172. https:\/\/doi.org\/10.1097\/00005537-200007000-00019","journal-title":"Laryngoscope"},{"key":"1547_CR14","doi-asserted-by":"publisher","unstructured":"Knosp E, Steiner E, Kitz K, Matula C (1993) Pituitary adenomas with invasion of the cavernous sinus space: a magnetic resonance imaging classification compared with surgical findings. Neurosurgery 33:610\u20137 discussion 617\u20138. https:\/\/doi.org\/10.1227\/00006123-199310000-00008","DOI":"10.1227\/00006123-199310000-00008"},{"key":"1547_CR15","volume-title":"Last\u2019s anatomy, regional and applied","author":"RJ Last","year":"1994","unstructured":"Last RJ, McMinn RMH (1994) Last\u2019s anatomy, regional and applied, 9th edn. Churchill Livingstone, Edinburgh","edition":"9"},{"key":"1547_CR16","doi-asserted-by":"publisher","first-page":"36","DOI":"10.3340\/jkns.2015.58.1.36","volume":"58","author":"J-H Park","year":"2015","unstructured":"Park J-H, Choi JH, Kim Y-I, Kim SW, Hong Y-K (2015) Modified graded repair of cerebrospinal fluid leaks in endoscopic endonasal transsphenoidal surgery. J Korean Neurosurg Soc 58:36\u201342. https:\/\/doi.org\/10.3340\/jkns.2015.58.1.36","journal-title":"J Korean Neurosurg Soc"},{"key":"1547_CR17","doi-asserted-by":"publisher","first-page":"661","DOI":"10.3171\/2013.4.jns13124","volume":"119","author":"KS Patel","year":"2013","unstructured":"Patel KS, Komotar RJ, Szentirmai O, Moussazadeh N, Raper DM, Starke RM, Anand VK, Schwartz TH (2013) Case-specific protocol to reduce cerebrospinal fluid leakage after endonasal endoscopic surgery. J Neurosurg 119:661\u2013668. https:\/\/doi.org\/10.3171\/2013.4.jns13124","journal-title":"J Neurosurg"},{"key":"1547_CR18","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1055\/s-0030-1253573","volume":"20","author":"M Patel","year":"2010","unstructured":"Patel M, Stadler M, Snyderman C, Carrau R, Kassam A, Germanwala A, Gardner P, Zanation A (2010) How to choose? endoscopic skull base reconstructive options and limitations. Skull Base Off J North Am Skull Base Soc Al 20:397\u2013404. https:\/\/doi.org\/10.1055\/s-0030-1253573","journal-title":"Skull Base Off J North Am Skull Base Soc Al"},{"key":"1547_CR19","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1067\/mhn.2002.121022","volume":"126","author":"JF Piccirillo","year":"2016","unstructured":"Piccirillo JF, Merritt MG Jr, Richards ML (2016) Psychometric and clinimetric validity of the 20-item Sino-Nasal Outcome Test (Snot-20). Otolaryngol Head Neck Surg 126:41\u201347. https:\/\/doi.org\/10.1067\/mhn.2002.121022","journal-title":"Otolaryngol Head Neck Surg"},{"key":"1547_CR20","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1080\/00016480701730752","volume":"128","author":"T-M Yoon","year":"2008","unstructured":"Yoon T-M, Lim S-C, Jung S (2008) Utility of sphenoid mucosal flaps in transnasal transsphenoidal surgery. Acta Otolaryngol (Stockh) 128:785\u2013789. https:\/\/doi.org\/10.1080\/00016480701730752","journal-title":"Acta Otolaryngol (Stockh)"},{"key":"1547_CR21","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/j.wneu.2017.01.119","volume":"101","author":"Q Zhou","year":"2017","unstructured":"Zhou Q, Yang Z, Wang X, Wang Z, Zhao C, Zhang S, Li P, Li S, Liu P (2017) Risk factors and management of intraoperative cerebrospinal fluid leaks in endoscopic treatment of pituitary adenoma: analysis of 492 patients. World Neurosurg 101:390\u2013395. https:\/\/doi.org\/10.1016\/j.wneu.2017.01.119","journal-title":"World Neurosurg"}],"container-title":["Neurosurgical Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-021-01547-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10143-021-01547-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-021-01547-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T06:05:06Z","timestamp":1644386706000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10143-021-01547-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,22]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["1547"],"URL":"https:\/\/doi.org\/10.1007\/s10143-021-01547-9","relation":{},"ISSN":["0344-5607","1437-2320"],"issn-type":[{"value":"0344-5607","type":"print"},{"value":"1437-2320","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,22]]},"assertion":[{"value":"12 February 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 March 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 April 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 April 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"No part of this article has been previously published or presented.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"HREC 15386Q.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not deemed necessary by ethics board.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not deemed necessary by ethics board.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}