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To date, there is no consensus regarding its role as intervention preceding the operation of tumour removal. The aim of this prospective open-label controlled study is to assess if ETV prevents secondary HCP after tumour removal and if ETV influences the early results of tumour surgery. The study was performed on 68 patients operated for tumours of the third ventricle and posterior fossa. In 30 patients, ETV was performed several days before tumour removal, while in 38 patients, the tumour was removed during a one-stage procedure without ETV. Patients who did not receive ETV before the tumour removal procedure had a higher probability of developing postoperative HCP (n\u2009=\u200912, p\u2009=\u20090.03). They also demonstrated a substantially higher rate of early postoperative complications (n\u2009=\u200920, p\u2009=\u20090.002) and a lower Karnofsky score (p\u2009=\u20090.004) than patients in whom ETV was performed before tumour removal. The performance of external ventricular drainage in the non-ETV group did not prevent secondary HCP (p\u2009=\u20090.68). Postoperative cerebellar swelling (p\u2009=\u20090.01), haematoma (p\u2009=\u20090.04), cerebrospinal fluid leak (p\u2009=\u20090.04) and neuroinfection (p\u2009=\u20090.04) were the main risk factors of persistent HCP. Performance of ETV before tumour removal is not only beneficial for control of acute HCP but also prevents the occurrence of secondary postoperative HCP and may also minimize early postoperative complications.<\/jats:p>","DOI":"10.1007\/s10143-021-01570-w","type":"journal-article","created":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T23:21:02Z","timestamp":1626909662000},"page":"771-781","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Endoscopic third ventriculostomy before surgery of third ventricle and posterior fossa tumours decreases the risk of secondary hydrocephalus and early postoperative complications"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8638-3871","authenticated-orcid":false,"given":"Pawel","family":"Tabakow","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6614-7721","authenticated-orcid":false,"given":"Artur","family":"Weiser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2318-7130","authenticated-orcid":false,"given":"Malgorzata","family":"Burzynska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6809-5884","authenticated-orcid":false,"given":"Przemyslaw","family":"Blauciak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,7,22]]},"reference":[{"key":"1570_CR1","doi-asserted-by":"publisher","first-page":"52","DOI":"10.3171\/jns.1977.46.1.0052","volume":"46","author":"L Albright","year":"1977","unstructured":"Albright L, Reigel DH (1977) Management of hydrocephalus secondary to posterior fossa tumors. 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The study was approved by the Bioethics Committee of the Wroclaw Medical University.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individuals to participate in this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Informed consent was obtained from all individual participants for publication of the results of this study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}