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We proposed a modified classification to separately divide III-CBTs into different subgroups on the basis of arterial relevant features and anatomical relevant features.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Materials and methods<\/jats:title>\n            <jats:p>From 2020 to 2023, a total of 129 III-CBTs at a single institution were retrospectively analyzed. All cases were independently classified as arterial-relevant and anatomical-relevant subgroups. The pre-, peri- and postoperative data were summarized and compared accordingly.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Among the 129 cases, 69 cases were identified as \u201cClassical type\u201d, 23 cases as \u201cMedial type\u201d, 27 cases as \u201cLateral type\u201d and 10 cases as \u201cEnveloped type\u201d according to arterial morphologies. Besides, 76 cases were identified as \u201cCommon type\u201d, 15 cases as \u201cPharynx- invasion type\u201d, 18 cases as \u201cSkull base-invasion type\u201d and 20 cases as \u201cMixed type\u201d according to anatomical relationships. \u201cEnveloped type\u201d of tumors in arterial-relevant classification and \u201cMixed type\u201d of tumors in anatomical-relevant classification are the most challenging cases for surgeons with the lowest resection rate, highest incidence of carotid arteries injury and postoperative stroke.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>The modified classifications provide comprehensive understanding of different III-CBTs which are applicable for individualized treatment in clinical practice.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s10143-024-02389-x","type":"journal-article","created":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T11:01:53Z","timestamp":1712314913000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Novel insights into the classification of Shamblin III carotid body tumors from a neurosurgical perspective"],"prefix":"10.1007","volume":"47","author":[{"given":"Qianquan","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Si","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanzhong","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfeng","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoliang","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,5]]},"reference":[{"issue":"2","key":"2389_CR1","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.ejvs.2007.01.015","volume":"34","author":"MS Sajid","year":"2007","unstructured":"Sajid MS, Hamilton G, Baker DM (2007) Joint Vascular Research, a multicenter review of carotid body tumour management. 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