{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T05:33:40Z","timestamp":1741152820434,"version":"3.38.0"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T00:00:00Z","timestamp":1719273600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T00:00:00Z","timestamp":1719273600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002352","name":"Ain Shams University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002352","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurosurg Rev"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>After myelomeningocele (MMC) repair, a secondary tethered spinal cord occurs in almost all patients. The tethered spinal cord may result in progressive neurological deterioration and walking disability. This retrospective cohort study aimed to highlight the walking recovery one year after tethered cord release and its relation to the preoperative conus level. We reviewed the medical records at our university hospital from January 2014 to December 2022. The patients who underwent spinal cord untethering following lumbosacral MMC repair were included. We assessed the walking recovery one year after cord release using the modified Benzel scale. Thirty-seven patients met our selection criteria. There were 19 girls (51.4%) and 18 boys (48.6%). Their mean age at presentation was 8.6 years. The preoperative conus vertebral levels ranged between L4 and S3. One year after spinal cord release, 37.8% of the patients regained their walking ability. All the patients whose preoperative conus level was at S2 or S3 regained their walking ability. In contrast, all the patients with preoperative conus levels at L4 or L5 didn\u2019t regain their ability to walk. One-third (33.3%) of patients whose conus was at the S1 level regained their walking ability one year after cord release. One year after tethered cord release, 37.8% of the patients regained their walking ability. We found that the walking recovery was statistically associated with the preoperative conus level. A multicenter prospective study is required to support the results of this study.<\/jats:p>","DOI":"10.1007\/s10143-024-02497-8","type":"journal-article","created":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T03:52:21Z","timestamp":1719287541000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Walking recovery after tethered cord release"],"prefix":"10.1007","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3432-0988","authenticated-orcid":false,"given":"Mohamed AR","family":"AbdelFatah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aly","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameh","family":"Hefny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,6,25]]},"reference":[{"key":"2497_CR1","doi-asserted-by":"publisher","first-page":"201","DOI":"10.3389\/fncel.2020.00201","volume":"14","author":"K -Janik","year":"2020","unstructured":"Janik K, Manire MA, Smith GM, Krynska B (2020) Spinal cord Injury in Myelomeningocele: prospects for Therapy. Front Cell Neurosci 14:201","journal-title":"Front Cell Neurosci"},{"issue":"2","key":"2497_CR2","doi-asserted-by":"publisher","first-page":"E7","DOI":"10.3171\/foc.2004.16.2.8","volume":"16","author":"RJ -Hudgins","year":"2004","unstructured":"Hudgins RJ, Gilreath CL (2004) Tethered spinal cord following repair of myelomeningocele. Neurosurg Focus 16(2):E7","journal-title":"Neurosurg Focus"},{"issue":"7","key":"2497_CR3","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1179\/016164104225018027","volume":"26","author":"S -Yamada","year":"2004","unstructured":"Yamada S, Knerium DS, Mandybur GM, Schultz RL, Yamada BS (2004) Pathophysiology of tethered cord syndrome and other complex factors. Neurol Res 26(7):722\u2013726","journal-title":"Neurol Res"},{"issue":"7","key":"2497_CR4","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1007\/PL00007291","volume":"16","author":"N -Ohe","year":"2000","unstructured":"Ohe N, Futamura A, Kawada R, Minatsu H, Kohmura H, Hayashi K et al (2000) Secondary tethered cord syndrome in spinal dysraphism. Childs Nerv Syst 16(7):457\u2013461","journal-title":"Childs Nerv Syst"},{"issue":"10","key":"2497_CR5","first-page":"e10949","volume":"12","author":"LM -Ferreira Furtado","year":"2020","unstructured":"Ferreira Furtado LM, Da Costa Val Filho JA, Dantas F, Moura de Sousa C (2020) Tethered cord syndrome after Myelomeningocele Repair: A literature update. Cureus 12(10):e10949","journal-title":"Cureus"},{"issue":"9","key":"2497_CR6","doi-asserted-by":"publisher","first-page":"467","DOI":"10.2176\/nmc.oa.2017-0017","volume":"57","author":"MA -AbdelFatah","year":"2017","unstructured":"AbdelFatah MA (2017) The walking Recovery one year after Surgical Management of Thoracolumbar Burst fracture in paraplegic patients. Neurol Med Chir (Tokyo) 57(9):467\u2013471","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"2497_CR7","doi-asserted-by":"crossref","unstructured":"Sun J, Zhang Y, Wang H, Wang Y, Yang Y, Kong Q et al) Clinical outcomes of primary and revision untethering surgery in patients with tethered cord syndrome and spinal Bifida. World Neurosurg 116:e66\u2013e70","DOI":"10.1016\/j.wneu.2018.03.221"},{"issue":"5","key":"2497_CR8","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1159\/000120739","volume":"19","author":"JM -Herman","year":"1993","unstructured":"Herman JM, McLone DG, Storrs BB, Dauser RC (1993) Analysis of 153 patients with myelomeningocele or spinal lipoma reoperated upon for a tethered cord. Presentation, management, and outcome. Pediatr Neurosurg 19(5):243\u2013249","journal-title":"Pediatr Neurosurg"}],"container-title":["Neurosurgical Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-024-02497-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10143-024-02497-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-024-02497-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T10:43:33Z","timestamp":1741085013000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10143-024-02497-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,25]]},"references-count":8,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2497"],"URL":"https:\/\/doi.org\/10.1007\/s10143-024-02497-8","relation":{},"ISSN":["1437-2320"],"issn-type":[{"type":"electronic","value":"1437-2320"}],"subject":[],"published":{"date-parts":[[2024,6,25]]},"assertion":[{"value":"11 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 June 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 June 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"None declared by the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"None.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Source of support"}},{"value":"This study was approved by the Research Ethics Committee, Faculty of Medicine, Ain Shams University (FWA 000017585). Date of approval: 20\/3\/2023 (reference number: FMASU R 60\/ 2023).","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not Applicable. This research study was conducted retrospectively from data obtained for clinical purposes. This manuscript does not contain any individual person\u2019s data.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate and consent to publish"}}],"article-number":"292"}}