{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:29:06Z","timestamp":1786980546202,"version":"build-2736575974"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T00:00:00Z","timestamp":1759363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T00:00:00Z","timestamp":1759363200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Liaoning Province Education Administration","award":["2022-MS-074"],"award-info":[{"award-number":["2022-MS-074"]}]},{"name":"Liaoning Province Education Administration","award":["LJKMZ20221209,LJKMZ20221179,JYTMS20230110"],"award-info":[{"award-number":["LJKMZ20221209,LJKMZ20221179,JYTMS20230110"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurosurg Rev"],"DOI":"10.1007\/s10143-025-03792-8","type":"journal-article","created":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T06:19:10Z","timestamp":1759385950000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association of compression pressure and SCN8A and SCN9A gene polymorphisms with the recurrence of balloon compression-treated trigeminal neuralgia"],"prefix":"10.1007","volume":"48","author":[{"given":"Xin","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiu","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanfeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quancai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangkun","family":"Jing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,2]]},"reference":[{"key":"3792_CR1","first-page":"1","volume":"38","author":"Headache Classification Committee of the International Headache Society (IHS)","year":"2018","unstructured":"Headache Classification Committee of the International Headache Society (IHS) (2018) The international classification of headache disorders, 3rd edition. Cephalalgia 38:1\u2013211","journal-title":"Cephalalgia"},{"key":"3792_CR2","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1097\/AAP.0000000000000292","volume":"40","author":"JL De C\u00f3rdoba","year":"2015","unstructured":"De C\u00f3rdoba JL, Garc\u00eda Bach M, Isach N, Piles S (2015) Percutaneous balloon compression for trigeminal neuralgia: imaging and technical aspects. Reg Anesth Pain Med 40:616\u2013622","journal-title":"Reg Anesth Pain Med"},{"key":"3792_CR3","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.jocn.2023.12.019","volume":"120","author":"Q Tang","year":"2024","unstructured":"Tang Q, Gao S, Wang C, Guan Z, Zhang J, Huang H, Li Y, Ma Y, Yan Z (2024) Clinical observation of perioperative negative emotional changes in patients with percutaneous balloon compression for primary trigeminal neuralgia: a prospective cohort study. J Clin Neurosci 120:5\u201311","journal-title":"J Clin Neurosci"},{"key":"3792_CR4","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1111\/ene.13950","volume":"26","author":"L Bendtsen","year":"2019","unstructured":"Bendtsen L, Zakrzewska JM, Abbott J, Braschinsky M, Di Stefano G, Donnet A, Eide PK, Leal PRL, Maarbjerg S, May A et al (2019) European academy of neurology guideline on trigeminal neuralgia. Eur J Neurol 26:831\u2013849","journal-title":"Eur J Neurol"},{"key":"3792_CR5","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.3171\/jns.1983.59.6.1007","volume":"59","author":"S Mullan","year":"1983","unstructured":"Mullan S, Lichtor T (1983) Percutaneous microcompression of the trigeminal ganglion for trigeminal neuralgia. J Neurosurg 59:1007\u20131012","journal-title":"J Neurosurg"},{"key":"3792_CR6","first-page":"25","volume":"10","author":"JS Cheng","year":"2014","unstructured":"Cheng JS, Lim DA, Chang EF, Barbaro NM (2014) A review of percutaneous treatments for trigeminal neuralgia. Neurosurgery 10:25\u201333","journal-title":"Neurosurgery"},{"key":"3792_CR7","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2022.843982","volume":"9","author":"H Wang","year":"2022","unstructured":"Wang H, Chen C, Chen D, Li F, Hu S, Ding W, Wang J, Chen W (2022) Clinical analysis of the treatment of primary trigeminal neuralgia by percutaneous balloon compression. Front Surg 9:843982","journal-title":"Front Surg"},{"key":"3792_CR8","first-page":"e1255","volume":"24","author":"X Fan","year":"2021","unstructured":"Fan X, Xu F, Ren H, Lu Z, Bu H, Ma L, Kong C, Wang T (2021) The analysis of percutaneous balloon compression on efficacy and negative emotion in the treatment of recurrent trigeminal neuralgia after surgical procedures. Pain Physician 24:e1255\u2013e1262","journal-title":"Pain Physician"},{"key":"3792_CR9","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1080\/02688697.2020.1787341","volume":"35","author":"MW Li","year":"2021","unstructured":"Li MW, Jiang XF, Niu CS (2021) Efficacy of and risk factors for percutaneous balloon compression for trigeminal neuralgia in elderly patients. Br J Neurosurg 35:280\u2013284","journal-title":"Br J Neurosurg"},{"key":"3792_CR10","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000008199","volume":"96","author":"X Ying","year":"2017","unstructured":"Ying X, Wang H, Deng S, Chen Y, Zhang J, Yu W (2017) Long-term outcome of percutaneous balloon compression for trigeminal neuralgia patients elder than 80 years: a STROBE-compliant article. Medicine (Baltimore) 96:e8199","journal-title":"Medicine (Baltimore)"},{"key":"3792_CR11","doi-asserted-by":"publisher","first-page":"3905","DOI":"10.1007\/s00701-023-05823-z","volume":"165","author":"P Huang","year":"2023","unstructured":"Huang P, Liu H, Liu Z, Huang L, Lu M, Wang L, Yu Y, Jin X (2023) Effectiveness of percutaneous balloon compression (PBC) in improving physical function and quality of life in trigeminal neuralgia: a retrospective study. Acta Neurochir (Wien) 165:3905\u20133912","journal-title":"Acta Neurochir (Wien)"},{"key":"3792_CR12","doi-asserted-by":"crossref","unstructured":"Stomal-S\u0142owi\u0144ska M, S\u0142owi\u0144ski J, Lee TK, Uitti RJ, Deen HG, Reimer R, Cheshire WP Jr., Herzog-Bryan G, Wharen RE Jr. (2011) Correlation of clinical findings and results of percutaneous balloon compression for patients with trigeminal neuralgia. Clin Neurol Neurosurg 113:14\u201321","DOI":"10.1016\/j.clineuro.2010.08.005"},{"key":"3792_CR13","doi-asserted-by":"publisher","DOI":"10.3171\/foc.2005.18.5.11","volume":"18","author":"JA Brown","year":"2005","unstructured":"Brown JA, Pilitsis JG (2005) Percutaneous balloon compression for the treatment of trigeminal neuralgia: results in 56 patients based on balloon compression pressure monitoring. Neurosurg Focus 18:E10","journal-title":"Neurosurg Focus"},{"key":"3792_CR14","doi-asserted-by":"publisher","first-page":"e892","DOI":"10.1016\/j.wneu.2018.03.111","volume":"114","author":"SS Grewal","year":"2018","unstructured":"Grewal SS, Kerezoudis P, Garcia O, Quinones-Hinojosa A, Reimer R, Wharen RE (2018) Results of percutaneous balloon compression in trigeminal pain syndromes. World Neurosurg 114:e892\u2013e899","journal-title":"World Neurosurg"},{"key":"3792_CR15","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1007\/s40122-021-00311-7","volume":"10","author":"Q Wang","year":"2021","unstructured":"Wang Q, Chen C, Guo G, Li Z, Huang D, Zhou H (2021) A prospective study to examine the association of the foramen ovale size with intraluminal pressure of pear-shaped balloon in percutaneous balloon compression for trigeminal neuralgia. Pain Ther 10:1439\u20131450","journal-title":"Pain Ther"},{"key":"3792_CR16","doi-asserted-by":"publisher","first-page":"E345","DOI":"10.36076\/ppj.2024.7.E345","volume":"27","author":"Y Peng","year":"2024","unstructured":"Peng Y, Zou C, Li Y, Li Q, Long H, Yang W, Xiao Z, Jiang L, Gao W, He Y (2024) Balloon pressure and clinical effectiveness of percutaneous microballoon compression in the treatment of primary trigeminal neuralgia. Pain Physician 27:E345-e353","journal-title":"Pain Physician"},{"key":"3792_CR17","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/j.jocn.2022.03.022","volume":"99","author":"W Lv","year":"2022","unstructured":"Lv W, Hu W, Chi L, Zhang L (2022) Factors that may affect recurrence of trigeminal neuralgia after percutaneous balloon compression. J Clin Neurosci 99:248\u2013252","journal-title":"J Clin Neurosci"},{"key":"3792_CR18","doi-asserted-by":"crossref","unstructured":"Zakrzewska JM, Linskey ME: 2014 Trigeminal neuralgia. BMJ Clin Evid 2014","DOI":"10.1136\/bmj.g474"},{"key":"3792_CR19","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1007\/s10143-021-01514-4","volume":"45","author":"M Liu","year":"2022","unstructured":"Liu M, Tang S, Li T, Xu Z, Li S, Zhou Y, Li L, Wang W, Shi J, Shi W (2022) Prognostic nomogram for percutaneous balloon compression in the treatment of trigeminal neuralgia. Neurosurg Rev 45:561\u2013569","journal-title":"Neurosurg Rev"},{"key":"3792_CR20","doi-asserted-by":"publisher","first-page":"1396","DOI":"10.3171\/2022.2.JNS212644","volume":"137","author":"A Kourilsky","year":"2022","unstructured":"Kourilsky A, Palpacuer C, Rogers A, Chauvet D, Wiart C, Bourdillon P, Le Gu\u00e9rinel C (2022) Multivariate models to predict pain recurrence and sensitive complications after percutaneous balloon compression in trigeminal neuralgia. J Neurosurg 137:1396\u20131405","journal-title":"J Neurosurg"},{"key":"3792_CR21","doi-asserted-by":"publisher","DOI":"10.1007\/s10143-024-02339-7","volume":"47","author":"K Chen","year":"2024","unstructured":"Chen K, Wu J, Mei H, Cai Y, Chai S, Shen L, Yang J, Xu D, Zhao S, Jiang P et al (2024) A nomogram based on radiomics and clinical information to predict prognosis in percutaneous balloon compression for the treatment of trigeminal neuralgia. Neurosurg Rev 47:109","journal-title":"Neurosurg Rev"},{"key":"3792_CR22","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/1129-2377-15-42","volume":"15","author":"W Cui","year":"2014","unstructured":"Cui W, Yu X, Zhang H (2014) The serotonin transporter gene polymorphism is associated with the susceptibility and the pain severity in idiopathic trigeminal neuralgia patients. J Headache Pain 15:42","journal-title":"J Headache Pain"},{"key":"3792_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2021.106880","volume":"208","author":"J Romero","year":"2021","unstructured":"Romero J, Costa GMF, Rocha LPC, Siqueira S, Moreira PR, Almeida-Leite CM (2021) Polymorphisms of Nav1.6 sodium channel, Brain-derived Neurotrophic Factor, Catechol-O-methyltransferase and Guanosine Triphosphate Cyclohydrolase 1 genes in trigeminal neuralgia. Clin Neurol Neurosurg 208:106880","journal-title":"Clin Neurol Neurosurg"},{"key":"3792_CR24","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/s13041-020-00725-y","volume":"14","author":"E Gambeta","year":"2021","unstructured":"Gambeta E, Gandini MA, Souza IA, Ferron L, Zamponi GW (2021) A CACNA1A variant associated with trigeminal neuralgia alters the gating of Cav21 channels. Mol Brain 14:4","journal-title":"Mol Brain"},{"key":"3792_CR25","doi-asserted-by":"publisher","first-page":"174480692090189","DOI":"10.1177\/1744806920901890","volume":"16","author":"E Gambeta","year":"2020","unstructured":"Gambeta E, Chichorro JG, Zamponi GW (2020) Trigeminal neuralgia: an overview from pathophysiology to pharmacological treatments. Mol Pain 16:1744806920901890","journal-title":"Mol Pain"},{"key":"3792_CR26","doi-asserted-by":"publisher","first-page":"174480692110161","DOI":"10.1177\/17448069211016139","volume":"17","author":"MA Mannerak","year":"2021","unstructured":"Mannerak MA, Lashkarivand A, Eide PK (2021) Trigeminal neuralgia and genetics: a systematic review. Mol Pain 17:17448069211016140","journal-title":"Mol Pain"},{"key":"3792_CR27","doi-asserted-by":"publisher","first-page":"338","DOI":"10.2119\/molmed.2016.00131","volume":"22","author":"BS Tanaka","year":"2016","unstructured":"Tanaka BS, Zhao P, Dib-Hajj FB, Morisset V, Tate S, Waxman SG, Dib-Hajj SD (2016) A gain-of-function mutation in Nav1.6 in a case of trigeminal neuralgia. Mol Med 22:338\u2013348","journal-title":"Mol Med"},{"key":"3792_CR28","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1016\/j.tins.2007.08.004","volume":"30","author":"SD Dib-Hajj","year":"2007","unstructured":"Dib-Hajj SD, Cummins TR, Black JA, Waxman SG (2007) From genes to pain: Na v 1.7 and human pain disorders. Trends Neurosci 30:555\u2013563","journal-title":"Trends Neurosci"},{"key":"3792_CR29","doi-asserted-by":"publisher","first-page":"5016","DOI":"10.3168\/jds.2023-24452","volume":"107","author":"PR Menta","year":"2024","unstructured":"Menta PR, Prim J, de Oliveira E, Lima F, Galv\u00e3o KN, Noyes N, Ballou MA, Machado VS (2024) Predictive models for metritis cure using farm-collected data, metabolic and inflammation biomarkers, and hemogram variables measured at diagnosis. J Dairy Sci 107:5016\u20135028","journal-title":"J Dairy Sci"},{"key":"3792_CR30","doi-asserted-by":"publisher","first-page":"4294","DOI":"10.1038\/s41598-024-54560-5","volume":"14","author":"T Jayakrishnan","year":"2024","unstructured":"Jayakrishnan T, Mariam A, Farha N, Rotroff DM, Aucejo F, Barot SV, Conces M, Nair KG, Krishnamurthi SS, Schmit SL et al (2024) Plasma metabolomic differences in early-onset compared to average-onset colorectal cancer. Sci Rep 14:4294","journal-title":"Sci Rep"},{"key":"3792_CR31","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1590\/S0004-282X2011000200016","volume":"69","author":"WK Campos","year":"2011","unstructured":"Campos WK, Linhares MN (2011) A prospective study of 39 patients with trigeminal neuralgia treated with percutaneous balloon compression. Arq Neuropsiquiatr 69:221\u2013226","journal-title":"Arq Neuropsiquiatr"},{"key":"3792_CR32","doi-asserted-by":"publisher","first-page":"3805","DOI":"10.2147\/JPR.S343783","volume":"14","author":"C Sun","year":"2021","unstructured":"Sun C, Zheng W, Zhu Q, Du Q, Yu W (2021) The transformation of the balloon shape in percutaneous balloon compression for trigeminal neuralgia. J Pain Res 14:3805\u20133814","journal-title":"J Pain Res"},{"key":"3792_CR33","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/S0090-3019(03)00514-7","volume":"60","author":"HA Wilkinson","year":"2003","unstructured":"Wilkinson HA (2003) Percutaneous trigeminal ganglion balloon compression for treatment of trigeminal neuralgia\u2013part I: pressure recordings. Surg Neurol 60:470","journal-title":"Surg Neurol"},{"key":"3792_CR34","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S0090-3019(03)00253-2","volume":"60","author":"ST Lee","year":"2003","unstructured":"Lee ST, Chen JF (2003) Percutaneous trigeminal ganglion balloon compression for treatment of trigeminal neuralgia, part II: results related to compression duration. Surg Neurol 60:149\u201353","journal-title":"Surg Neurol"},{"key":"3792_CR35","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/j.neuroscience.2009.08.037","volume":"164","author":"SR Siqueira","year":"2009","unstructured":"Siqueira SR, Alves B, Malpartida HM, Teixeira MJ, Siqueira JT (2009) Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia. Neuroscience 164:573\u2013577","journal-title":"Neuroscience"},{"key":"3792_CR36","doi-asserted-by":"publisher","first-page":"1310419","DOI":"10.3389\/fneur.2023.1310419","volume":"14","author":"H Fang","year":"2023","unstructured":"Fang H, Hu W, Kang Q, Kuang X, Wang L, Zhang X, Liao H, Yang L, Yang H, Jiang Z, Wu L (2023) Clinical characteristics and genetic analysis of pediatric patients with sodium channel gene mutation-related childhood epilepsy: a review of 94 patients. Front Neurol 14:1310419","journal-title":"Front Neurol"},{"key":"3792_CR37","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/0006-8993(84)91314-3","volume":"294","author":"SG Waxman","year":"1984","unstructured":"Waxman SG, Wood SL (1984) Impulse conduction in inhomogeneous axons: effects of variation in voltage-sensitive ionic conductances on invasion of demyelinated axon segments and preterminal fibers. Brain Res 294:111\u2013122","journal-title":"Brain Res"},{"key":"3792_CR38","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1186\/s12883-023-03478-y","volume":"24","author":"M Hebbar","year":"2024","unstructured":"Hebbar M, Al-Taweel N, Gill I, Boelman C, Dean RA, Goodchild SJ, Mezeyova J, Shuart NG, Johnson JP Jr, Lee J et al (2024) Expanding the genotype-phenotype spectrum in SCN8A-related disorders. BMC Neurol 24:31","journal-title":"BMC Neurol"},{"key":"3792_CR39","unstructured":"<Identification of the NRF2 transcriptional network.pdf>."},{"key":"3792_CR40","doi-asserted-by":"publisher","first-page":"5148","DOI":"10.1073\/pnas.0913181107","volume":"107","author":"F Reimann","year":"2010","unstructured":"Reimann F, Cox JJ, Belfer I, Diatchenko L, Zaykin DV, McHale DP, Drenth JP, Dai F, Wheeler J, Sanders F et al (2010) Pain perception is altered by a nucleotide polymorphism in SCN9A. Proc Natl Acad Sci U S A 107:5148\u20135153","journal-title":"Proc Natl Acad Sci U S A"},{"key":"3792_CR41","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1093\/bmb\/ldaa003","volume":"133","author":"I Drissi","year":"2020","unstructured":"Drissi I, Woods WA, Woods CG (2020) Understanding the genetic basis of congenital insensitivity to pain. Br Med Bull 133:65\u201378","journal-title":"Br Med Bull"},{"key":"3792_CR42","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1038\/nature05413","volume":"444","author":"JJ Cox","year":"2006","unstructured":"Cox JJ, Reimann F, Nicholas AK, Thornton G, Roberts E, Springell K, Karbani G, Jafri H, Mannan J, Raashid Y et al (2006) An SCN9A channelopathy causes congenital inability to experience pain. Nature 444:894\u2013898","journal-title":"Nature"},{"key":"3792_CR43","doi-asserted-by":"publisher","first-page":"1362","DOI":"10.1093\/pm\/pny191","volume":"20","author":"GMF Costa","year":"2019","unstructured":"Costa GMF, Rocha LPC, Siqueira S, Moreira PR, Almeida-Leite CM (2019) No association of polymorphisms in Nav1.7 or nerve growth factor receptor genes with trigeminal neuralgia. Pain Med 20:1362\u20131369","journal-title":"Pain Med"}],"container-title":["Neurosurgical Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-025-03792-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10143-025-03792-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-025-03792-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T04:20:58Z","timestamp":1772079658000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10143-025-03792-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,2]]},"references-count":43,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["3792"],"URL":"https:\/\/doi.org\/10.1007\/s10143-025-03792-8","relation":{},"ISSN":["1437-2320"],"issn-type":[{"value":"1437-2320","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,2]]},"assertion":[{"value":"20 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 August 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 August 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 October 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study has been approved by the Ethics Committee of Liaoning Provincial People's Hospital in accordance with the Declaration of Helsinki (approval number: 2022HS009), and informed consent has been obtained from all participants.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study and Written informed consent was obtained.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"675"}}