{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T16:03:41Z","timestamp":1781712221701,"version":"3.54.5"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:00:00Z","timestamp":1769817600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:00:00Z","timestamp":1769817600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurosurg Rev"],"DOI":"10.1007\/s10143-025-04054-3","type":"journal-article","created":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T04:41:49Z","timestamp":1769834509000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Analysis of radiological markers in normal pressure hydrocephalus and their association with postoperative outcomes following shunt procedures"],"prefix":"10.1007","volume":"49","author":[{"given":"Diego F.","family":"Gomez-Amarillo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ericka","family":"Ramirez-Arquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6200-6143","authenticated-orcid":false,"given":"Juan Daniel","family":"Ramirez-Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Fuentes-Tapias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria P.","family":"Vargas-Osorio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Mejia-Michelsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jurgen M.","family":"Gonzalez-Jimenez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Ramos-M\u00e1rquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Bermudez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo B. O.","family":"Brenner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael","family":"Bertani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"de la Hoz-Valle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan A.","family":"Mejia-Cordovez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan F.","family":"Ramon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique","family":"Jimenez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar G.","family":"Ordo\u00f1ez-Rubiano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Hakim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,31]]},"reference":[{"issue":"1","key":"4054_CR1","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-024-06239-z","volume":"166","author":"J Moyet","year":"2024","unstructured":"Moyet J, Baledent O, Slovenski T, Todessayi P, Metanbou S, Deschasse G, Bloch F, Capel C (2024) Assessment of neurofluid dynamics in relation to clinical improvement after tap-test: pilot study. Acta Neurochir (Wien) 166(1):358. https:\/\/doi.org\/10.1007\/s00701-024-06239-z","journal-title":"Acta Neurochir (Wien)"},{"issue":"4","key":"4054_CR2","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1590\/1980-57642015DN94000350","volume":"9","author":"BP Damasceno","year":"2015","unstructured":"Damasceno BP (2015) Neuroimaging in normal pressure hydrocephalus. Dement Neuropsychol 9(4):350\u2013355. https:\/\/doi.org\/10.1590\/1980-57642015DN94000350","journal-title":"Dement Neuropsychol"},{"issue":"4","key":"4054_CR3","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/0022-510x(65)90016-x","volume":"2","author":"S Hakim","year":"1965","unstructured":"Hakim S, Adams RD (1965) The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure. J Neurol Sci 2(4):307\u201327. https:\/\/doi.org\/10.1016\/0022-510x(65)90016-x","journal-title":"J Neurol Sci"},{"key":"4054_CR4","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2024.1338755","volume":"16","author":"Y Yang","year":"2024","unstructured":"Yang Y, Yan M, Liu X, Li S, Lin G (2024) Improve the diagnosis of idiopathic normal pressure hydrocephalus by combining abnormal cortical thickness and ventricular morphometry. Front Aging Neurosci 16:1338755. https:\/\/doi.org\/10.3389\/fnagi.2024.1338755","journal-title":"Front Aging Neurosci"},{"key":"4054_CR5","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.700269","volume":"12","author":"R Yin","year":"2021","unstructured":"Yin R, Wen J, Wei J (2021) Progression in neuroimaging of normal pressure hydrocephalus. Front Neurol 12:700269. https:\/\/doi.org\/10.3389\/fneur.2021.700269","journal-title":"Front Neurol"},{"issue":"8","key":"4054_CR6","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1016\/j.jalz.2017.01.013","volume":"13","author":"D Jaraj","year":"2017","unstructured":"Jaraj D, Wikkels\u00f8 C, Rabiei K, Marlow T, Jensen C, \u00d6stling S, Skoog I (2017) Mortality and risk of dementia in normal-pressure hydrocephalus: a population study. Alzheimers Dement 13(8):850\u2013857. https:\/\/doi.org\/10.1016\/j.jalz.2017.01.013","journal-title":"Alzheimers Dement"},{"issue":"2","key":"4054_CR7","doi-asserted-by":"publisher","first-page":"63","DOI":"10.2176\/nmc.st.2020-0292","volume":"61","author":"M Nakajima","year":"2021","unstructured":"Nakajima M, Yamada S, Miyajima M, Ishii K, Kuriyama N, Kazui H et al (2021) Guidelines for management of idiopathic normal pressure hydrocephalus (Third Edition): endorsed by the Japanese Society of Normal Pressure Hydrocephalus. Neurol Med Chir (Tokyo) 61(2):63\u201397. https:\/\/doi.org\/10.2176\/nmc.st.2020-0292","journal-title":"Neurol Med Chir (Tokyo)"},{"issue":"5","key":"4054_CR8","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.3390\/biomedicines11051265","volume":"11","author":"ES Pyrgelis","year":"2023","unstructured":"Pyrgelis ES, Velonakis G, Papageorgiou SG, Stefanis L, Kapaki E, Constantinides VC (2023) Imaging markers for normal pressure hydrocephalus: an overview. Biomedicines 11(5):1265. https:\/\/doi.org\/10.3390\/biomedicines11051265","journal-title":"Biomedicines"},{"issue":"1","key":"4054_CR9","doi-asserted-by":"publisher","first-page":"74","DOI":"10.3174\/ajnr.A5910","volume":"40","author":"S Agerskov","year":"2019","unstructured":"Agerskov S, Wallin M, Hellstr\u00f6m P, Ziegelitz D, Wikkels\u00f6 C, Tullberg M (2019) Absence of disproportionately enlarged subarachnoid space hydrocephalus, a sharp callosal angle, or other morphologic MRI markers should not be used to exclude patients with idiopathic normal pressure hydrocephalus from shunt surgery. AJNR Am J Neuroradiol 40(1):74\u201379. https:\/\/doi.org\/10.3174\/ajnr.A5910","journal-title":"AJNR Am J Neuroradiol"},{"key":"4054_CR10","doi-asserted-by":"publisher","unstructured":"Toma AK, Holl E, Kitchen ND, Watkins LD (2011) Evans\u2019 index revisited: the need for an alternative in normal pressure hydrocephalus. Neurosurgery 68(4):939\u2013944. https:\/\/doi.org\/10.1227\/NEU.0b013e318208f5e0","DOI":"10.1227\/NEU.0b013e318208f5e0"},{"issue":"7","key":"4054_CR11","first-page":"1277","volume":"19","author":"H Kitagaki","year":"1998","unstructured":"Kitagaki H, Mori E, Ishii K, Yamaji S, Hirono N, Imamura T (1998) Csf spaces in idiopathic normal pressure hydrocephalus: morphology and volumetry. AJNR Am J Neuroradiol 19(7):1277\u20131284","journal-title":"AJNR Am J Neuroradiol"},{"key":"4054_CR12","doi-asserted-by":"publisher","first-page":"2556","DOI":"10.1007\/s00415-020-09844-x","volume":"267","author":"M Todisco","year":"2020","unstructured":"Todisco M, Picascia M, Pisano P, Zangaglia R, Minafra B, Vitali P, Rognone E, Pichiecchio A, Ceravolo R, Vanacore N et al (2020) Lumboperitoneal shunt in idiopathic normal pressure hydrocephalus: a prospective controlled study. J Neurol 267:2556\u20132566. https:\/\/doi.org\/10.1007\/s00415-020-09844-x","journal-title":"J Neurol"},{"key":"4054_CR13","doi-asserted-by":"publisher","first-page":"2311","DOI":"10.1007\/s00701-016-2980-4","volume":"158","author":"AJ Luikku","year":"2016","unstructured":"Luikku AJ, Hall A, Nerg O, Koivisto AM, Hiltunen M, Helisalmi S, Herukka SK, Sutela A, Kojoukhova M, Mattila J et al (2016) Multimodal analysis to predict shunt surgery outcome of 284 patients with suspected idiopathic normal pressure hydrocephalus. Acta Neurochir 158:2311\u20132319. https:\/\/doi.org\/10.1007\/s00701-016-2980-4","journal-title":"Acta Neurochir"},{"key":"4054_CR14","first-page":"31","volume":"12","author":"WG Bradley","year":"1991","unstructured":"Bradley WG, Whittemore AR, Watanabe AS et al (1991) Association of deep matter infarction with chronic communicating hydrocephalus: implications regarding the possible origin of normal-pressure hydrocephalus. Am J Neuroradiol 12:31\u201339","journal-title":"Am J Neuroradiol"},{"key":"4054_CR15","doi-asserted-by":"publisher","first-page":"59","DOI":"10.4103\/2152-7806.154777","volume":"6","author":"K Reinard","year":"2015","unstructured":"Reinard K, Basheer A, Phillips S et al (2015) Simple and reproducible linear measurements to determine ventricular enlargement in adults. Surg Neurol Int 6:59\u201359. https:\/\/doi.org\/10.4103\/2152-7806.154777","journal-title":"Surg Neurol Int"},{"key":"4054_CR16","doi-asserted-by":"publisher","first-page":"11860","DOI":"10.18632\/oncotarget.7644","volume":"7","author":"P Missori","year":"2016","unstructured":"Missori P, Rughetti A, Peschillo S, Gualdi G, Di Biasi C, Nofroni I, Marinelli L, Fattapposta F, Curra A (2016) In normal aging ventricular system never attains pathological values of Evans\u2019 index. Oncotarget 7:11860\u201311863. https:\/\/doi.org\/10.18632\/oncotarget.7644","journal-title":"Oncotarget"},{"key":"4054_CR17","doi-asserted-by":"publisher","first-page":"178","DOI":"10.3171\/2013.8.JNS13575","volume":"120","author":"J Virhammar","year":"2014","unstructured":"Virhammar J, Laurell K, Cesarini KG, Larsson EM (2014a) The callosal angle measured on MRI as a predictor of outcome in idiopathic normal pressure hydrocephalus. J Neurosurg 120:178\u2013184. https:\/\/doi.org\/10.3171\/2013.8.JNS13575","journal-title":"J Neurosurg"},{"key":"4054_CR18","doi-asserted-by":"publisher","first-page":"2678","DOI":"10.1007\/s00330-008-1044-4","volume":"18","author":"K Ishii","year":"2008","unstructured":"Ishii K, Kanda T, Harada A, Miyamoto N, Kawaguchi T, Shimada K et al (2008) Clinical impact of the callosal angle in the diagnosis of idiopathic normal pressure hydrocephalus. Eur Radiol 18:2678\u201383. https:\/\/doi.org\/10.1007\/s00330-008-1044-4","journal-title":"Eur Radiol"},{"issue":"12","key":"4054_CR19","doi-asserted-by":"publisher","first-page":"2311","DOI":"10.3174\/ajnr.A4046","volume":"35","author":"J Virhammar","year":"2014","unstructured":"Virhammar J, Laurell K, Cesarini KG, Larsson EM (2014) Preoperative prognostic value of MRI findings in 108 patients with idiopathic normal pressure hydrocephalus. AJNR Am J Neuroradiol 35(12):2311\u20138. https:\/\/doi.org\/10.3174\/ajnr.A4046","journal-title":"AJNR Am J Neuroradiol"},{"issue":"2","key":"4054_CR20","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1007\/s00701-022-05402-8","volume":"165","author":"SG Thavarajasingam","year":"2023","unstructured":"Thavarajasingam SG, El-Khatib M, Vemulapalli K, Iradukunda HAS, K SV, Borchert R, Russo S, Eide PK (2023) Radiological predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis. Acta Neurochir (Wien) 165(2):369\u2013419. https:\/\/doi.org\/10.1007\/s00701-022-05402-8","journal-title":"Acta Neurochir (Wien)"},{"key":"4054_CR21","doi-asserted-by":"publisher","first-page":"1709","DOI":"10.1007\/s00701-015-2503-8","volume":"157","author":"M Kojoukhova","year":"2015","unstructured":"Kojoukhova M, Koivisto AM, Korhonen R (2015) Feasibility of radiological markers in idiopathic normal pressure hydrocephalus. Acta Neurochir (Wien) 157:1709\u20131719. https:\/\/doi.org\/10.1007\/s00701-015-2503-8","journal-title":"Acta Neurochir (Wien)"},{"key":"4054_CR22","doi-asserted-by":"publisher","first-page":"831","DOI":"10.3174\/ajnr.A4124","volume":"36","author":"WG Bradley Jr.","year":"2015","unstructured":"Bradley WG Jr. (2015) CSF flow in the brain in the context of normal pressure hydrocephalus. AJNR Am J Neuroradiol 36:831\u20138. https:\/\/doi.org\/10.3174\/ajnr.A4124","journal-title":"AJNR Am J Neuroradiol"},{"issue":"2","key":"4054_CR23","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1007\/s00234-007-0318-x","volume":"50","author":"M Sasaki","year":"2008","unstructured":"Sasaki M, Honda S, Yuasa T, Iwamura A, Shibata E, Ohba H (2008) Narrow CSF space at high convexity and high midline areas in idiopathic normal pressure hydrocephalus detected by axial and coronal MRI. Neuroradiology 50(2):117\u201322. https:\/\/doi.org\/10.1007\/s00234-007-0318-x","journal-title":"Neuroradiology"},{"key":"4054_CR24","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/1743-8454-7-18","volume":"7","author":"M Hashimoto","year":"2010","unstructured":"Hashimoto M, Ishikawa M, Mori E, Kuwana N (2010) Study of INPH on neurological improvement (SINPHONI). Diagnosis of idiopathic normal pressure hydrocephalus is supported by MRI-based scheme: a prospective cohort study. Cerebrospinal Fluid Res 7:18. https:\/\/doi.org\/10.1186\/1743-8454-7-18","journal-title":"Cerebrospinal Fluid Res"},{"key":"4054_CR25","first-page":"1277","volume":"19","author":"H Kitagaki","year":"1998","unstructured":"Kitagaki H, Mori E, Ishii K, Yamaji S, Hirono N, Imamura T (1998) CSF spaces in idiopathic normal pressure hydrocephalus: morphology and volumetry. AJNR Am J Neuroradiol 19:1277\u20131284","journal-title":"AJNR Am J Neuroradiol"},{"key":"4054_CR26","doi-asserted-by":"publisher","first-page":"742","DOI":"10.3171\/jns.1998.89.5.0742","volume":"89","author":"AI Holodny","year":"1998","unstructured":"Holodny AI, George AE, De Leon MJ (1998) Focal dilation and paradoxical collapse of cortical fissures and sulci in patients with normal-pressure hydrocephalus. J Neurosurg 89:742\u2013747. https:\/\/doi.org\/10.3171\/jns.1998.89.5.0742","journal-title":"J Neurosurg"},{"key":"4054_CR27","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/S1474-4422(15)00046-0","volume":"14","author":"H Kazui","year":"2015","unstructured":"Kazui H, Miyajima M, Mori E, Ishikawa M (2015) Lumboperitoneal shunt surgery for idiopathic normal pressure hydrocephalus (SINPHONI-2): an open-label randomised trial. Lancet Neurol 14:585\u2013594. https:\/\/doi.org\/10.1016\/S1474-4422(15)00046-0","journal-title":"Lancet Neurol"},{"key":"4054_CR28","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1016\/j.jocn.2016.09.004","volume":"34","author":"CL Craven","year":"2016","unstructured":"Craven CL, Toma AK, Mostafa T, Patel N, Watkins LD (2016) The predictive value of DESH for shunt responsiveness in idiopathic normal pressure hydrocephalus. J Clin Neurosci 34:294\u20138. https:\/\/doi.org\/10.1016\/j.jocn.2016.09.004","journal-title":"J Clin Neurosci"},{"key":"4054_CR29","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.jns.2018.01.017","volume":"387","author":"YJ Hong","year":"2018","unstructured":"Hong YJ, Kim MJ, Jeong E, Kim JE, Hwang J, Lee JI, Lee JH, Na DL (2018) Preoperative biomarkers in patients with idiopathic normal pressure hydrocephalus showing a favorable shunt surgery outcome. J Neurol Sci 387:21\u201326. https:\/\/doi.org\/10.1016\/j.jns.2018.01.017","journal-title":"J Neurol Sci"},{"key":"4054_CR30","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1159\/000119521","volume":"25","author":"K Ishii","year":"2008","unstructured":"Ishii K, Kawaguchi T, Shimada K et al (2008) Voxel-based analysis of gray matter and CSF space in idiopathic normal pressure hydrocephalus. Dement Geriatr Cogn Disord 25:329\u2013335","journal-title":"Dement Geriatr Cogn Disord"},{"key":"4054_CR31","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1007\/s00234-009-0610-z","volume":"52","author":"F Yamashita","year":"2010","unstructured":"Yamashita F, Sasaki M, Takahashi S et al (2010) Detection of changes in cerebrospinal fluid space in idiopathic normal pressure hydrocephalus using voxel-based morphometry. Neuroradiology 52:381\u2013386","journal-title":"Neuroradiology"},{"key":"4054_CR32","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1007\/s00415-010-5602-8","volume":"257","author":"WJ Lee","year":"2010","unstructured":"Lee WJ, Wang SJ, Hsu LC, Lirng JF, Wu CH, Fuh JL (2010) Brain MRI as a predictor of CSF tap test response in patients with idiopathic normal pressure hydrocephalus. J Neurol 257:1675\u20131681","journal-title":"J Neurol"},{"key":"4054_CR33","doi-asserted-by":"publisher","unstructured":"Jack CR, Mokri B, Laws ER et al (1987) MR findings in normal-pressure hydrocephalus: significance and comparison with other forms of dementia. J Comput Assist Tomogr. https:\/\/doi.org\/10.1097\/00004728-198711000-00001","DOI":"10.1097\/00004728-198711000-00001"},{"key":"4054_CR34","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1097\/00006123-199703000-00011","volume":"40","author":"JK Krauss","year":"1997","unstructured":"Krauss JK, Regel JP, Vach W, Orszagh M, Jungling FD, Bohus M, Droste DW (1997) White matter lesions in patients with idiopathic normal pressure hydrocephalus and in an age-matched control group: a comparative study. Neurosurgery 40:491\u2013495. https:\/\/doi.org\/10.1097\/00006123-199703000-00011","journal-title":"Neurosurgery"},{"key":"4054_CR35","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1016\/j.clineuro.2007.07.012","volume":"109","author":"P Bugalho","year":"2007","unstructured":"Bugalho P, Alves L (2007) Normal-pressure hydrocephalus: white matter lesions correlate negatively with gait improvement after lumbar puncture. Clin Neurol Neurosurg 109:774\u2013778. https:\/\/doi.org\/10.1016\/j.clineuro.2007.07.012","journal-title":"Clin Neurol Neurosurg"}],"container-title":["Neurosurgical Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-025-04054-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10143-025-04054-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-025-04054-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T04:41:51Z","timestamp":1769834511000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10143-025-04054-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,31]]},"references-count":35,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4054"],"URL":"https:\/\/doi.org\/10.1007\/s10143-025-04054-3","relation":{},"ISSN":["1437-2320"],"issn-type":[{"value":"1437-2320","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,31]]},"assertion":[{"value":"8 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 December 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was conducted in accordance with the principles of the Declaration of Helsinki and was approved by the Corporate Committee on Research Ethics of Fundaci\u00f3n Santa Fe de Bogot\u00e1 (CCEI-16600-2024).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Informed consent for the publication of the data included in this manuscript was obtained from all participants.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"180"}}