{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T19:21:12Z","timestamp":1785007272889,"version":"3.55.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Public Hospital Joint Research Fund Scientific and Technological Project","award":["2024GLLH0117"],"award-info":[{"award-number":["2024GLLH0117"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurosurg Rev"],"DOI":"10.1007\/s10143-025-04058-z","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:53:38Z","timestamp":1768784018000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Morphological and hemodynamic determinants of rupture in mirror posterior communicating artery aneurysms"],"prefix":"10.1007","volume":"49","author":[{"given":"Gai","family":"Hang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangheng","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shalamagai","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiran","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbo","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhitong","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianhao","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"4058_CR1","doi-asserted-by":"publisher","first-page":"514","DOI":"10.7326\/0003-4819-159-8-201310150-00004","volume":"159","author":"MH Li","year":"2013","unstructured":"Li MH, Chen SW, Li YD, Chen YC, Cheng YS, Hu DJ, Tan HQ, Wu Q, Wang W, Sun ZK, Wei XE, Zhang JY, Qiao RH, Zong WH, Zhang Y, Lou W, Chen ZY, Zhu Y, Peng DR, Ding SX, Xu XF, Hou XH, Jia WP (2013) Prevalence of unruptured cerebral aneurysms in Chinese adults aged 35 to 75 years: a cross-sectional study. Ann Intern Med 159:514\u2013521. https:\/\/doi.org\/10.7326\/0003-4819-159-8-201310150-00004","journal-title":"Ann Intern Med"},{"key":"4058_CR2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.2.205","author":"MW Joanna","year":"2000","unstructured":"Joanna MW, Phil W (2000) The detection and management of unruptured intracranial aneurysms. Brain. https:\/\/doi.org\/10.1093\/brain\/123.2.205","journal-title":"Brain"},{"key":"4058_CR3","doi-asserted-by":"publisher","unstructured":"Dennis JN, Larissa ES, Ale A, Francisca HHL, Nicolien KdR, Gabri\u00ebl JER (2009) Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis. The Lancet. Neurology. https:\/\/doi.org\/10.1016\/s1474-4422(09)70126-7","DOI":"10.1016\/s1474-4422(09)70126-7"},{"key":"4058_CR4","doi-asserted-by":"publisher","DOI":"10.1227\/01.Neu.0000316847.64140.81","author":"D Sujan","year":"2008","unstructured":"Sujan D, Markus T, Mocco J, Minsuok K, Junichi Y, Adnan HS, Hopkins LN, Hui M (2008) Morphology parameters for intracranial aneurysm rupture risk assessment. Neurosurgery. https:\/\/doi.org\/10.1227\/01.Neu.0000316847.64140.81","journal-title":"Neurosurgery"},{"key":"4058_CR5","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200103000-00007","author":"U Hiroshi","year":"2001","unstructured":"Hiroshi U, Tamano Y, Kuri S, Tomokatsu H (2001) Is the aspect ratio a reliable index for predicting the rupture of a saccular aneurysm? Neurosurgery. https:\/\/doi.org\/10.1097\/00006123-200103000-00007","journal-title":"Neurosurgery"},{"key":"4058_CR6","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2005.102.2.0355","author":"LR Madhavan","year":"2005","unstructured":"Madhavan LR, Baoshun M, Robert EH (2005) Quantified aneurysm shape and rupture risk. J Neurosurg. https:\/\/doi.org\/10.3171\/jns.2005.102.2.0355","journal-title":"J Neurosurg"},{"key":"4058_CR7","doi-asserted-by":"publisher","unstructured":"Xiang J, Vincent MT, Kenneth VS, Hui M (2013) CFD: computational fluid dynamics or confounding factor dissemination? The role of hemodynamics in intracranial aneurysm rupture risk assessment. AJNR. American journal of neuroradiology. https:\/\/doi.org\/10.3174\/ajnr.A3710","DOI":"10.3174\/ajnr.A3710"},{"key":"4058_CR8","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2005.103.4.0649","author":"Y Ichiro","year":"2005","unstructured":"Ichiro Y, Yuichi M, Fernando V (2005) Endovascular management of dissecting vertebrobasilar artery aneurysms in patients presenting with acute subarachnoid hemorrhage. J Neurosurg. https:\/\/doi.org\/10.3171\/jns.2005.103.4.0649","journal-title":"J Neurosurg"},{"key":"4058_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2019.03.275","author":"L Heng-Jian","year":"2019","unstructured":"Heng-Jian L, Han Z, Donglin L, Yingbin J, Songfeng C, Jing C, Xujin Y, Jinyang R, Shifang L, Wei L, Jingchen G, Yong Y, Jinxiang X, Pi-Ning Z, Yugong F (2019) Intracranial Mirror Aneurysm: Epidemiology, Rupture Risk, New Imaging, Controversies, and Treatment Strategies. World neurosurgery. https:\/\/doi.org\/10.1016\/j.wneu.2019.03.275","journal-title":"World neurosurgery"},{"key":"4058_CR10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2017.09.015","author":"H Zhongqing","year":"2017","unstructured":"Zhongqing H, Xin-Wei Z, Zhongjun H, Sui-Qiao H, Zhihua M, Xianlong W, Hao Y, Lv-Jin F, Qiu-jing W, Ping-An L, Zhibo W (2017) Risk factors analysis of mirror aneurysms: a multi-center retrospective study based on clinical and demographic profile of patients. Eur J Radiol. https:\/\/doi.org\/10.1016\/j.ejrad.2017.09.015","journal-title":"Eur J Radiol"},{"key":"4058_CR11","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2017-013553","author":"W Guangxian","year":"2018","unstructured":"Guangxian W, Jun L, You-qiang C, Wen L, Ming-guang Y, Mingfu G, Dong Z (2018) Morphological characteristics associated with the rupture risk of mirror posterior communicating artery aneurysms. J Neurointerv Surg. https:\/\/doi.org\/10.1136\/neurintsurg-2017-013553","journal-title":"J Neurointerv Surg"},{"key":"4058_CR12","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2004.101.4.0676","author":"H Yiemeng","year":"2004","unstructured":"Yiemeng H, Hui M, Scott W, Bernard RB, Ricard\u00f3 AH, Lee RG, Hopkins LN (2004) Effects of arterial geometry on aneurysm growth: three-dimensional computational fluid dynamics study. J Neurosurg. https:\/\/doi.org\/10.3171\/jns.2004.101.4.0676","journal-title":"J Neurosurg"},{"key":"4058_CR13","doi-asserted-by":"publisher","DOI":"10.1227\/01.Neu.0000341529.11231.69","author":"T Markus","year":"2009","unstructured":"Markus T, Sujan D, Elad IL, Mocco J, Hui M (2009) Influence of intracranial aneurysm-to-parent vessel size ratio on hemodynamics and implication for rupture: results from a virtual experimental study. Neurosurgery. https:\/\/doi.org\/10.1227\/01.Neu.0000341529.11231.69","journal-title":"Neurosurgery"},{"key":"4058_CR14","doi-asserted-by":"publisher","unstructured":"Gerald ML, Jeffrey SH, Sam PJ, Vivek RD, Robert FS (2002) Cerebral revascularization performed using posterior inferior cerebellar artery-posterior inferior cerebellar artery bypass. Report of four cases and literature review. Journal of neurosurgery. https:\/\/doi.org\/10.3171\/jns.2002.97.1.0219","DOI":"10.3171\/jns.2002.97.1.0219"},{"key":"4058_CR15","doi-asserted-by":"publisher","first-page":"2474","DOI":"10.1056\/NEJMoa1113260","volume":"366","author":"A Morita","year":"2012","unstructured":"Morita A, Kirino T, Hashi K, Aoki N, Fukuhara S, Hashimoto N, Nakayama T, Sakai M, Teramoto A, Tominari S, Yoshimoto T (2012) The natural course of unruptured cerebral aneurysms in a Japanese cohort. N Engl J Med 366:2474\u20132482. https:\/\/doi.org\/10.1056\/NEJMoa1113260","journal-title":"N Engl J Med"},{"key":"4058_CR16","doi-asserted-by":"publisher","first-page":"1799","DOI":"10.3171\/2017.2.Jns162705","volume":"128","author":"H Maslehaty","year":"2018","unstructured":"Maslehaty H, Capone C, Frantsev R, Fischer I, Jabbarli R, Cornelius JF, Kamp MA, Cappabianca P, Sure U, Steiger HJ, Petridis AK (2018) Predictive anatomical factors for rupture in middle cerebral artery mirror bifurcation aneurysms. J Neurosurg 128:1799\u20131807. https:\/\/doi.org\/10.3171\/2017.2.Jns162705","journal-title":"J Neurosurg"},{"key":"4058_CR17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0094837","volume":"9","author":"A Ho","year":"2014","unstructured":"Ho A, Lin N, Charoenvimolphan N, Stanley M, Frerichs KU, Day AL, Du R (2014) Morphological parameters associated with ruptured posterior communicating aneurysms. PLoS One 9:e94837. https:\/\/doi.org\/10.1371\/journal.pone.0094837","journal-title":"PLoS One"},{"key":"4058_CR18","doi-asserted-by":"publisher","unstructured":"Mocco J, Brown RD Jr, Torner JC, Capuano AW, Fargen KM, Raghavan ML, Piepgras DG, Meissner I, Huston J III (2018) Aneurysm morphology and prediction of rupture: an international study of unruptured intracranial aneurysms analysis. Neurosurgery 82:491\u2013496. https:\/\/doi.org\/10.1093\/neuros\/nyx226","DOI":"10.1093\/neuros\/nyx226"},{"key":"4058_CR19","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.731129","volume":"12","author":"JH Yin","year":"2021","unstructured":"Yin JH, Su SX, Zhang X, Bi YM, Duan CZ, Huang WM, Wang XL (2021) U-shaped association of aspect ratio and single intracranial aneurysm rupture in Chinese patients: a cross-sectional study. Front Neurol 12:731129. https:\/\/doi.org\/10.3389\/fneur.2021.731129","journal-title":"Front Neurol"},{"key":"4058_CR20","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1161\/strokeaha.109.574244","volume":"41","author":"M Rahman","year":"2010","unstructured":"Rahman M, Smietana J, Hauck E, Hoh B, Hopkins N, Siddiqui A, Levy EI, Meng H, Mocco J (2010) Size ratio correlates with intracranial aneurysm rupture status: a prospective study. Stroke 41:916\u2013920. https:\/\/doi.org\/10.1161\/strokeaha.109.574244","journal-title":"Stroke"},{"key":"4058_CR21","doi-asserted-by":"publisher","first-page":"2169","DOI":"10.1161\/strokeaha.113.001138","volume":"44","author":"D Kashiwazaki","year":"2013","unstructured":"Kashiwazaki D, Kuroda S (2013) Size ratio can highly predict rupture risk in intracranial small (<5 mm) aneurysms. Stroke 44:2169\u20132173. https:\/\/doi.org\/10.1161\/strokeaha.113.001138","journal-title":"Stroke"},{"key":"4058_CR22","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.775536","volume":"8","author":"X Zhai","year":"2021","unstructured":"Zhai X, Wang Y, Fang G, Hu P, Zhang H, Zhu C (2021) Case report: dynamic changes in hemodynamics during the formation and progression of intracranial aneurysms. Front Cardiovasc Med 8:775536. https:\/\/doi.org\/10.3389\/fcvm.2021.775536","journal-title":"Front Cardiovasc Med"},{"key":"4058_CR23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055413","volume":"8","author":"J Xu","year":"2013","unstructured":"Xu J, Yu Y, Wu X, Wu Y, Jiang C, Wang S, Huang Q, Liu J (2013) Morphological and hemodynamic analysis of mirror posterior communicating artery aneurysms. PLoS One 8:e55413. https:\/\/doi.org\/10.1371\/journal.pone.0055413","journal-title":"PLoS One"},{"key":"4058_CR24","doi-asserted-by":"publisher","first-page":"1436","DOI":"10.1161\/strokeaha.111.640995","volume":"43","author":"H Takao","year":"2012","unstructured":"Takao H, Murayama Y, Otsuka S, Qian Y, Mohamed A, Masuda S, Yamamoto M, Abe T (2012) Hemodynamic differences between unruptured and ruptured intracranial aneurysms during observation. Stroke 43:1436\u20131439. https:\/\/doi.org\/10.1161\/strokeaha.111.640995","journal-title":"Stroke"},{"key":"4058_CR25","doi-asserted-by":"publisher","first-page":"1240","DOI":"10.3171\/2009.10.Jns09759","volume":"112","author":"AM Nixon","year":"2010","unstructured":"Nixon AM, Gunel M, Sumpio BE (2010) The critical role of hemodynamics in the development of cerebral vascular disease. J Neurosurg 112:1240\u20131253. https:\/\/doi.org\/10.3171\/2009.10.Jns09759","journal-title":"J Neurosurg"},{"key":"4058_CR26","doi-asserted-by":"publisher","first-page":"587","DOI":"10.3174\/ajnr.A2339","volume":"32","author":"Z Kulcs\u00e1r","year":"2011","unstructured":"Kulcs\u00e1r Z, Ugron A, Marosfoi M, Berentei Z, Pa\u00e1l G, Szikora I (2011) Hemodynamics of cerebral aneurysm initiation: the role of wall shear stress and spatial wall shear stress gradient. AJNR Am J Neuroradiol 32:587\u2013594. https:\/\/doi.org\/10.3174\/ajnr.A2339","journal-title":"AJNR Am J Neuroradiol"},{"key":"4058_CR27","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000144648.89172.0f","author":"S Masaaki","year":"2004","unstructured":"Masaaki S, Oshima M, Kiyoshi T, Ryo T, Motoharu H, Kazuhiro K, Akio M, Takaaki K (2004) Magnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysms. Stroke. https:\/\/doi.org\/10.1161\/01.STR.0000144648.89172.0f","journal-title":"Stroke"},{"key":"4058_CR28","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1136\/neurintsurg-2014-011450","volume":"8","author":"G Duan","year":"2016","unstructured":"Duan G, Lv N, Yin J, Xu J, Hong B, Xu Y, Liu J, Huang Q (2016) Morphological and hemodynamic analysis of posterior communicating artery aneurysms prone to rupture: a matched case-control study. J Neurointerv Surg 8:47\u201351. https:\/\/doi.org\/10.1136\/neurintsurg-2014-011450","journal-title":"J Neurointerv Surg"},{"key":"4058_CR29","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1136\/neurintsurg-2014-011577","volume":"8","author":"J Liu","year":"2016","unstructured":"Liu J, Fan J, Xiang J, Zhang Y, Yang X (2016) Hemodynamic characteristics of large unruptured internal carotid artery aneurysms prior to rupture: a case control study. J Neurointerv Surg 8:367\u2013372. https:\/\/doi.org\/10.1136\/neurintsurg-2014-011577","journal-title":"J Neurointerv Surg"},{"key":"4058_CR30","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1159\/000339678","volume":"34","author":"S Omodaka","year":"2012","unstructured":"Omodaka S, Sugiyama S, Inoue T, Funamoto K, Fujimura M, Shimizu H, Hayase T, Takahashi A, Tominaga T (2012) Local hemodynamics at the rupture point of cerebral aneurysms determined by computational fluid dynamics analysis. Cerebrovasc Dis 34:121\u2013129. https:\/\/doi.org\/10.1159\/000339678","journal-title":"Cerebrovasc Dis"},{"key":"4058_CR31","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.wneu.2013.02.012","volume":"83","author":"K Fukazawa","year":"2015","unstructured":"Fukazawa K, Ishida F, Umeda Y, Miura Y, Shimosaka S, Matsushima S, Taki W, Suzuki H (2015) Using computational fluid dynamics analysis to characterize local hemodynamic features of middle cerebral artery aneurysm rupture points. World Neurosurg 83:80\u201386. https:\/\/doi.org\/10.1016\/j.wneu.2013.02.012","journal-title":"World Neurosurg"},{"key":"4058_CR32","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.781240","volume":"13","author":"W Zhong","year":"2022","unstructured":"Zhong W, Du Y, Kuang H, Liu M, Xue F, Bai X, Wang D, Su W, Wang Y (2022) Hemodynamic characteristic analysis of aneurysm wall enhancement in unruptured middle cerebral artery aneurysm. Front Neurol 13:781240. https:\/\/doi.org\/10.3389\/fneur.2022.781240","journal-title":"Front Neurol"}],"container-title":["Neurosurgical Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-025-04058-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10143-025-04058-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-025-04058-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T13:03:44Z","timestamp":1768827824000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10143-025-04058-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,19]]},"references-count":32,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4058"],"URL":"https:\/\/doi.org\/10.1007\/s10143-025-04058-z","relation":{},"ISSN":["1437-2320"],"issn-type":[{"value":"1437-2320","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,19]]},"assertion":[{"value":"25 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 November 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 December 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by The General Hospital of Chinese PLA Central Theater Command Institutional Review Board, Wuhan, China.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Informed consent was obtained from the patient for publication of this case report and any accompanying images.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}}],"article-number":"135"}}