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GA was used in 20 patients and AAA in 11 patients. Presurgical characteristics of the patients, intraoperative hemodynamic and physiological findings or complications and postoperative outcomes including ILAE scale scores at least 1 year of follow-up were analyzed using descriptive statistics and independent t-tests, Fisher\u2019s exact test, and \u03c7\u00b2 tests to identify differences between the groups.\u00a0During the surgery, there were no notable differences between the groups in terms of hemodynamic parameters, arterial blood gas measurements, or bleeding. However, the surgery length was longer in AAA group. Postoperative outcomes, including hospital stay duration, complication rates, and follow-up periods, were also comparable without significant differences. Neurological deficits were minimal in both groups, with no statistically significant differences between them. Most patients achieved positive results based on the ILAE classification in both groups, with most experiencing either no seizures or rare, non-disabling seizures.\u00a0AAA showed comparable results to general anesthesia, with no intraoperative complications or postoperative negative outcomes. However, due to the limited sample size, further evidence is needed to confirm its benefits in epilepsy surgery involving eloquent areas over GA.<\/jats:p>","DOI":"10.1007\/s10143-025-04112-w","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:48:37Z","timestamp":1770252517000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A pilot comparative study of intraoperative results and surgical outcomes between asleep-awake-asleep and general anesthesia modalities in temporal lobe resections"],"prefix":"10.1007","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6685-5851","authenticated-orcid":false,"given":"Daniel","family":"San-Juan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2991-2874","authenticated-orcid":false,"given":"Roberto","family":"Diaz-Peregrino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfonso","family":"Arellano-Reynoso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Alonso-Vanegas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alma Edith","family":"Gress-Mendoza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Nieto-Rizo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"Aguilar-Casta\u00f1eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel Angel","family":"Morales-Morales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David Omar","family":"L\u00f3pez-Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelin Zulema","family":"Camacho-Castillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,5]]},"reference":[{"key":"4112_CR1","doi-asserted-by":"publisher","first-page":"102522","DOI":"10.1016\/j.pmedr.2023.102522","volume":"36","author":"YJ Zhang","year":"2023","unstructured":"Zhang YJ, Kong XM, Lv JJ, Yang CH, Li XY, Yang XT, Guo ZL, Cheng ZH (2023) Analysis of the global burden of disease study highlights the global, regional, and National trends of idiopathic epilepsy epidemiology from 1990 to 2019. 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