{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T06:00:35Z","timestamp":1773208835816,"version":"3.50.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurosurg Rev"],"DOI":"10.1007\/s10143-025-04131-7","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T07:54:26Z","timestamp":1773129266000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Stereotactic radiosurgery (SRS) for primary intradural spinal tumors: A systematic review and meta-analysis"],"prefix":"10.1007","volume":"49","author":[{"given":"Emil O. R.","family":"Nordin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivek","family":"Sanker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Heesen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srinath","family":"Hariharan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Ciobanu-Caraus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Jose","family":"Cavagnaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikchan","family":"Jeon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John K.","family":"Ratliff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atman","family":"Desai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,10]]},"reference":[{"key":"4131_CR1","unstructured":"Holland-Frei Cancer Medicine. 6th Edition.; 2003"},{"issue":"4","key":"4131_CR2","doi-asserted-by":"publisher","first-page":"434","DOI":"10.6004\/jnccn.2011.0039","volume":"9","author":"K Aghayev","year":"2011","unstructured":"Aghayev K, Vrionis F, Chamberlain MC (2011) Adult intradural primary spinal cord tumors. J Natl Compr Canc Netw 9(4):434\u2013447","journal-title":"J Natl Compr Canc Netw"},{"issue":"6","key":"4131_CR3","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1093\/neuonc\/nox230","volume":"20","author":"MM Abd-El-Barr","year":"2018","unstructured":"Abd-El-Barr MM, Huang KT, Moses ZB, Iorgulescu JB, Chi JH (2018) Recent advances in intradural spinal tumors. Neuro Oncol 20(6):729\u2013742","journal-title":"Neuro Oncol"},{"key":"4131_CR4","unstructured":"Adult Central Nervous System Tumors Treatment. Published December 6, 2024. https:\/\/www.cancer.gov\/types\/brain\/patient\/adult-brain-treatment-pdq. Accessed March 12, 2025"},{"issue":"4","key":"4131_CR5","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1227\/01.neu.0000318174.28461.fc","volume":"62","author":"PC Gerszten","year":"2008","unstructured":"Gerszten PC, Burton SA, Ozhasoglu C, McCue KJ, Quinn AE (2008) Radiosurgery for benign intradural spinal tumors. Neurosurgery 62(4):887\u2013895 (discussion 895-896)","journal-title":"Neurosurgery"},{"issue":"6","key":"4131_CR6","doi-asserted-by":"publisher","first-page":"E10","DOI":"10.3171\/2009.9.FOCUS09194","volume":"27","author":"DA Shin","year":"2009","unstructured":"Shin DA, Huh R, Chung SS, Rock J, Ryu S (2009) Stereotactic spine radiosurgery for intradural and intramedullary metastasis. Neurosurg Focus 27(6):E10","journal-title":"Neurosurg Focus"},{"issue":"1","key":"4131_CR7","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.ncl.2012.09.011","volume":"31","author":"LL Mechtler","year":"2013","unstructured":"Mechtler LL, Nandigam K (2013) Spinal cord tumors: new views and future directions. Neurol Clin 31(1):241\u2013268","journal-title":"Neurol Clin"},{"issue":"1","key":"4131_CR8","doi-asserted-by":"publisher","first-page":"E11","DOI":"10.3171\/2016.9.FOCUS16356","volume":"42","author":"A Monserrate","year":"2017","unstructured":"Monserrate A, Zussman B, Ozpinar A, Niranjan A, Flickinger JC, Gerszten PC (2017) Stereotactic radiosurgery for intradural spine tumors using cone-beam CT image guidance. Neurosurg Focus 42(1):E11","journal-title":"Neurosurg Focus"},{"issue":"1","key":"4131_CR9","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.ijrobp.2016.09.014","volume":"97","author":"KJ Redmond","year":"2017","unstructured":"Redmond KJ, Robertson S, Lo SS, Soltys SG, Ryu S, McNutt T et al (2017) Consensus contouring guidelines for postoperative stereotactic body radiation therapy for metastatic solid tumor malignancies to the spine. Int J Radiat Oncol Biol Phys 97(1):64\u201374","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"9","key":"4131_CR10","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1016\/j.jocn.2012.02.002","volume":"19","author":"A Veeravagu","year":"2012","unstructured":"Veeravagu A, Lieberson RE, Mener A, Chen YR, Soltys SG, Gibbs IC et al (2012) CyberKnife stereotactic radiosurgery for the treatment of intramedullary spinal cord metastases. J Clin Neurosci 19(9):1273\u20131277","journal-title":"J Clin Neurosci"},{"issue":"6","key":"4131_CR11","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1177\/153303460700600602","volume":"6","author":"A Sahgal","year":"2007","unstructured":"Sahgal A, Chou D, Ames C, Ma L, Lamborn K, Huang K et al (2007) Image-guided robotic stereotactic body radiotherapy for benign spinal tumors: the University of California San Francisco preliminary experience. Technol Cancer Res Treat 6(6):595\u2013604","journal-title":"Technol Cancer Res Treat"},{"issue":"3","key":"4131_CR12","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1227\/NEU.0b013e318218db23","volume":"69","author":"S Sachdev","year":"2011","unstructured":"Sachdev S, Dodd RL, Chang SD, Soltys SG, Adler JR, Luxton G et al (2011) Stereotactic radiosurgery yields long-term control for benign intradural, extramedullary spinal tumors. Neurosurgery 69(3):533\u2013539 (discussion 539)","journal-title":"Neurosurgery"},{"issue":"1","key":"4131_CR13","doi-asserted-by":"publisher","first-page":"E12","DOI":"10.3171\/2016.10.FOCUS16361","volume":"42","author":"J Pan","year":"2017","unstructured":"Pan J, Ho AL, D\u2019Astous M, Sussman ES, Thompson PA, Tayag AT et al (2017) Image-guided stereotactic radiosurgery for treatment of spinal hemangioblastoma. Neurosurg Focus 42(1):E12","journal-title":"Neurosurg Focus"},{"issue":"6","key":"4131_CR14","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1093\/neuonc\/noz014","volume":"21","author":"R Kotecha","year":"2019","unstructured":"Kotecha R, Mehta MP, Chang EL, Brown PD, Suh JH, Lo SS et al (2019) Updates in the management of intradural spinal cord tumors: a radiation oncology focus. Neuro Oncol 21(6):707\u2013718","journal-title":"Neuro Oncol"},{"issue":"9","key":"4131_CR15","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1046\/j.1445-2197.2003.02748.x","volume":"73","author":"K Slim","year":"2003","unstructured":"Slim K, Nini E, Forestier D, Kwiatkowski F, Panis Y, Chipponi J (2003) Methodological index for non-randomized studies (minors): development and validation of a new instrument. ANZ J Surg 73(9):712\u2013716","journal-title":"ANZ J Surg"},{"issue":"5","key":"4131_CR16","doi-asserted-by":"publisher","first-page":"708","DOI":"10.1093\/neuros\/nyy442","volume":"85","author":"AL Chin","year":"2019","unstructured":"Chin AL, Fujimoto D, Kumar KA, Tupper L, Mansour S, Chang SD et al (2019) Long-term update of stereotactic radiosurgery for benign spinal tumors. Neurosurgery 85(5):708\u2013716","journal-title":"Neurosurgery"},{"issue":"1","key":"4131_CR17","doi-asserted-by":"publisher","first-page":"134","DOI":"10.5603\/RPOR.a2022.0003","volume":"27","author":"J Cvek","year":"2022","unstructured":"Cvek J, Knybel L, Reguli S, Lipina R, Hanzlikova P, \u0160ilh\u00e1n P et al (2022) Stereotactic radiotherapy for spinal hemangioblastoma - disease control and volume analysis in long-term follow up. Rep Pract Oncol Radiother 27(1):134\u2013141","journal-title":"Rep Pract Oncol Radiother"},{"issue":"2","key":"4131_CR18","doi-asserted-by":"publisher","first-page":"220","DOI":"10.3171\/2017.12.SPINE17920","volume":"29","author":"R Kalash","year":"2018","unstructured":"Kalash R, Glaser SM, Flickinger JC, Burton S, Heron DE, Gerszten PC et al (2018) Stereotactic body radiation therapy for benign spine tumors: is dose de-escalation appropriate? J Neurosurg Spine 29(2):220\u2013225","journal-title":"J Neurosurg Spine"},{"issue":"3","key":"4131_CR19","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1227\/neu.0000000000002728","volume":"94","author":"KH Yoo","year":"2024","unstructured":"Yoo KH, Park DJ, Marianayagam NJ, Gu X, Pollom EL, Soltys SG et al (2024) Stereotactic radiosurgery for cranial and spinal hemangioblastomas: a single-institution retrospective series. Neurosurgery 94(3):630\u2013642","journal-title":"Neurosurgery"},{"key":"4131_CR20","doi-asserted-by":"publisher","first-page":"73","DOI":"10.4103\/2152-7806.98386","volume":"3","author":"MT Selch","year":"2012","unstructured":"Selch MT, Tenn S, Agazaryan N, Lee SP, Gorgulho A, De Salles AAF (2012) Image-guided linear accelerator-based spinal radiosurgery for hemangioblastoma. Surg Neurol Int 3:73","journal-title":"Surg Neurol Int"},{"issue":"1","key":"4131_CR21","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1007\/s11060-010-0231-8","volume":"101","author":"UK Chang","year":"2011","unstructured":"Chang UK, Rhee CH, Youn SM, Lee DH, Park SQ (2011) Radiosurgery using the Cyberknife for benign spinal tumors: Korea Cancer Center Hospital experience. J Neurooncol 101(1):91\u201399","journal-title":"J Neurooncol"},{"issue":"9","key":"4131_CR22","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1007\/s11604-015-0455-9","volume":"33","author":"ME Lee","year":"2015","unstructured":"Lee ME, Hwang YJ, Sohn MJ, Lee BH, Kim SY (2015) Assessment of the treatment response of spinal meningiomas after radiosurgery focusing on serial MRI findings. Jpn J Radiol 33(9):547\u2013558","journal-title":"Jpn J Radiol"},{"issue":"7","key":"4131_CR23","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1007\/s00701-013-1756-3","volume":"155","author":"M Marchetti","year":"2013","unstructured":"Marchetti M, De Martin E, Milanesi I, Fariselli L (2013) Intradural extramedullary benign spinal lesions radiosurgery. Medium- to long-term results from a single institution experience. Acta Neurochir (Wien) 155(7):1215\u20131222","journal-title":"Acta Neurochir (Wien)"},{"issue":"1","key":"4131_CR24","doi-asserted-by":"publisher","first-page":"27","DOI":"10.7785\/tcrt.2012.500231","volume":"11","author":"M Kufeld","year":"2012","unstructured":"Kufeld M, Wowra B, Muacevic A, Zausinger S, Tonn JC (2012) Radiosurgery of spinal meningiomas and schwannomas. Technol Cancer Res Treat 11(1):27\u201334","journal-title":"Technol Cancer Res Treat"},{"issue":"4","key":"4131_CR25","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1227\/01.NEU.0000204128.84742.8F","volume":"58","author":"RL Dodd","year":"2006","unstructured":"Dodd RL, Ryu MR, Kamnerdsupaphon P, Gibbs IC, Chang SD Jr, Adler JR Jr (2006) CyberKnife radiosurgery for benign intradural extramedullary spinal tumors. Neurosurgery 58(4):674\u2013685 (discussion 674-685)","journal-title":"Neurosurgery"},{"issue":"4","key":"4131_CR26","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s00234-007-0345-7","volume":"50","author":"K Abul-Kasim","year":"2008","unstructured":"Abul-Kasim K, Thurnher MM, McKeever P, Sundgren PC (2008) Intradural spinal tumors: current classification and MRI features. Neuroradiology 50(4):301\u2013314","journal-title":"Neuroradiology"},{"issue":"Suppl 1","key":"4131_CR27","first-page":"i67","volume":"5","author":"WC Chen","year":"2023","unstructured":"Chen WC, Lucas CHG, Magill ST, Rogers CL, Raleigh DR (2023) Radiotherapy and radiosurgery for meningiomas. Neurooncol Adv 5(Suppl 1):i67\u2013i83","journal-title":"Neurooncol Adv"},{"issue":"1","key":"4131_CR28","doi-asserted-by":"publisher","first-page":"146","DOI":"10.3171\/2014.12.JNS141341","volume":"124","author":"G Harrison","year":"2016","unstructured":"Harrison G, Kano H, Lunsford LD, Flickinger JC, Kondziolka D (2016) Quantitative tumor volumetric responses after Gamma Knife radiosurgery for meningiomas. J Neurosurg 124(1):146\u2013154","journal-title":"J Neurosurg"},{"key":"4131_CR29","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.clineuro.2017.01.012","volume":"154","author":"KJ Bridges","year":"2017","unstructured":"Bridges KJ, Jaboin JJ, Kubicky CD, Than KD (2017) Stereotactic radiosurgery versus surgical resection for spinal hemangioblastoma: a systematic review. Clin Neurol Neurosurg 154:59\u201366","journal-title":"Clin Neurol Neurosurg"},{"issue":"1","key":"4131_CR30","doi-asserted-by":"publisher","first-page":"5","DOI":"10.52662\/nf.2024.00164","volume":"21","author":"MM Mosleh","year":"2025","unstructured":"Mosleh MM, Sohn MJ (2025) Radiosurgery for benign intradural extramedullary spinal tumors: a narrative review. Neurofunction 21(1):5\u201316","journal-title":"Neurofunction"},{"issue":"6","key":"4131_CR31","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1097\/00007632-200003150-00013","volume":"25","author":"F Gezen","year":"2000","unstructured":"Gezen F, Kahraman S, Canakci Z, Bed\u00fck A (2000) Review of 36 cases of spinal cord meningioma. Spine 25(6):727\u2013731","journal-title":"Spine"},{"issue":"1","key":"4131_CR32","first-page":"7","volume":"49","author":"S Peker","year":"2005","unstructured":"Peker S, Cer\u00e7i A, Ozgen S, Isik N, Kalelioglu M, Pamir MN (2005) Spinal meningiomas: evaluation of 41 patients. J Neurosurg Sci 49(1):7\u201311","journal-title":"J Neurosurg Sci"},{"issue":"2","key":"4131_CR33","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1227\/00006123-198908000-00001","volume":"25","author":"CL Solero","year":"1989","unstructured":"Solero CL, Fornari M, Giombini S, Lasio G, Oliveri G, Cimino C et al (1989) Spinal meningiomas: review of 174 operated cases. Neurosurgery 25(2):153\u2013160","journal-title":"Neurosurgery"},{"issue":"2 Suppl","key":"4131_CR34","doi-asserted-by":"publisher","first-page":"A67","DOI":"10.1227\/01.NEU.0000341628.98141.B6","volume":"64","author":"IC Gibbs","year":"2009","unstructured":"Gibbs IC, Patil C, Gerszten PC, Adler JR Jr, Burton SA (2009) Delayed radiation-induced myelopathy after spinal radiosurgery. Neurosurgery 64(2 Suppl):A67\u2013A72","journal-title":"Neurosurgery"},{"issue":"3","key":"4131_CR35","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1002\/cncr.22442","volume":"109","author":"S Ryu","year":"2007","unstructured":"Ryu S, Jin JY, Jin R, Rock J, Ajlouni M, Movsas B et al (2007) Partial volume tolerance of the spinal cord and complications of single-dose radiosurgery. Cancer 109(3):628\u2013636","journal-title":"Cancer"},{"issue":"Supplement3","key":"4131_CR36","doi-asserted-by":"publisher","first-page":"413","DOI":"10.3171\/sup.2004.101.supplement3.0413","volume":"101","author":"DL Benzil","year":"2004","unstructured":"Benzil DL, Saboori M, Mogilner AY, Rocchio R, Moorthy CR (2004) Safety and efficacy of stereotactic radiosurgery for tumors of the spine. J Neurosurg 101(Supplement3):413\u2013418","journal-title":"J Neurosurg"}],"container-title":["Neurosurgical Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-025-04131-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10143-025-04131-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-025-04131-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T07:54:30Z","timestamp":1773129270000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10143-025-04131-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,10]]},"references-count":36,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4131"],"URL":"https:\/\/doi.org\/10.1007\/s10143-025-04131-7","relation":{},"ISSN":["1437-2320"],"issn-type":[{"value":"1437-2320","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,10]]},"assertion":[{"value":"20 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 December 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 December 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 March 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Name of the approval committee"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human ethics and consent to participate declarations"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}},{"value":"The authors declare no competing interests.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"267"}}