{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T18:00:24Z","timestamp":1781632824151,"version":"3.54.5"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T00:00:00Z","timestamp":1770422400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T00:00:00Z","timestamp":1770422400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100012940","name":"Universit\u00e4tsklinikum T\u00fcbingen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012940","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurosurg Rev"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Microsurgical resection remains the gold standard in the treatment of spinal meningiomas. Available data suggest more favorable clinical outcomes compared to intracranial meningiomas. This study aims to enhance risk stratification and optimize treatment strategies by analyzing clinical and histopathological predictive factors for spinal meningiomas in a large single-center cohort.\u00a0We present the analysis of 217 spinal meningiomas of our institutional meningioma cohort treated between October 2003 and March 2017. Clinical parameters of the patients such as sex, age, location of the meningioma and extent of resection were recorded besides histological features. Other parameters included follow-up and recurrence. The outcome parameters for spinal meningiomas were evaluated and compared with 1767 intracranial meningiomas.\u00a0Among 217 spinal meningiomas, 80.37% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009172) were completely resected. The majority (96.31%,\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009209) were classified as CNS WHO grade 1. In contrast, the proportion of WHO grade 1 among intracranial meningiomas was 78.21% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20091382,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.0001). Patients with spinal meningiomas had a lower recurrence rate with 6.91% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200915), versus 23.94% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u2009423) of patients with intracranial meningiomas (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.0001). Multivariate analysis identified Simpson resection grade (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.0001) and higher WHO grade (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0156) as independent prognostic factors for risk factors for progression in spinal meningiomas. For intracranial meningiomas, male gender (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0106) and resection of a recurrent tumor (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.0001) were additionally identified as independent negative prognostic parameters.\u00a0Spinal meningiomas are associated with a more favorable prognosis compared to their intracranial counterparts. The most significant and modifiable prognostic factor is the achievement of gross total resection. Given the technical complexity of surgery, spinal meningiomas should preferably be treated in high-volume centers with experienced surgeons to achieve this goal while minimizing morbidity and ensuring durable tumor control.\n                  <\/jats:p>","DOI":"10.1007\/s10143-026-04151-x","type":"journal-article","created":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T08:05:39Z","timestamp":1770451539000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictive factors in spinal meningiomas \u2013 a comparative analysis with intracranial meningiomas of a high-volume skull and base center"],"prefix":"10.1007","volume":"49","author":[{"given":"Christina","family":"Fodi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"G\u00f6tt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Pa\u00dflack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Schittenhelm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"Tellermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Honegger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos","family":"Tatagiba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Behling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0306-1143","authenticated-orcid":false,"given":"Hannes","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,7]]},"reference":[{"issue":"10","key":"4151_CR1","doi-asserted-by":"publisher","first-page":"1742","DOI":"10.1093\/neuonc\/noae082","volume":"26","author":"JZ Wang","year":"2024","unstructured":"Wang JZ et al (2024) Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients, (in eng). Neuro Oncol 26(10):1742\u20131780. https:\/\/doi.org\/10.1093\/neuonc\/noae082","journal-title":"Neuro Oncol"},{"issue":"Supplement_6","key":"4151_CR2","doi-asserted-by":"publisher","first-page":"vi1","DOI":"10.1093\/neuonc\/noae145","volume":"26","author":"M Price","year":"2024","unstructured":"Price M et al (2024) CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2017\u20132021, (in eng). Neuro Oncol\u00a026(Supplement_6):vi1-vi85.\u00a0https:\/\/doi.org\/10.1093\/neuonc\/noae145","journal-title":"Neuro Oncol"},{"issue":"1","key":"4151_CR3","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.neuchi.2012.10.137","volume":"59","author":"H Riad","year":"2013","unstructured":"Riad H, Knafo S, Segnarbieux F, Lonjon N (2013) Spinal meningiomas: surgical outcome and literature review, (in eng). Neurochirurgie 59(1):30\u20134. https:\/\/doi.org\/10.1016\/j.neuchi.2012.10.137","journal-title":"Neurochirurgie"},{"issue":"6","key":"4151_CR4","doi-asserted-by":"publisher","first-page":"e2","DOI":"10.3171\/foc.2003.14.6.2","volume":"14","author":"ON Gottfried","year":"2003","unstructured":"Gottfried ON, Gluf W, Quinones-Hinojosa A, Kan P, Schmidt MH (2003) Spinal meningiomas: surgical management and outcome, (in eng). Neurosurg Focus\u00a014(6):e2.https:\/\/doi.org\/10.3171\/foc.2003.14.6.2","journal-title":"Neurosurg Focus"},{"issue":"2","key":"4151_CR5","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.critrevonc.2008.01.010","volume":"67","author":"C Marosi","year":"2008","unstructured":"Marosi C et al (2008) Meningioma, (in eng). Crit Rev Oncol Hematol 67(2):153\u201371. https:\/\/doi.org\/10.1016\/j.critrevonc.2008.01.010","journal-title":"Crit Rev Oncol Hematol"},{"issue":"21","key":"4151_CR6","doi-asserted-by":"publisher","first-page":"2161","DOI":"10.2217\/fon-2018-0006","volume":"14","author":"RA Buerki","year":"2018","unstructured":"Buerki RA, Horbinski CM, Kruser T, Horowitz PM, James CD, Lukas RV (2018) An overview of meningiomas, (in eng). Future Oncol 14(21):2161\u20132177. https:\/\/doi.org\/10.2217\/fon-2018-0006","journal-title":"Future Oncol"},{"issue":"3","key":"4151_CR7","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1016\/j.nec.2023.02.007","volume":"34","author":"VM Ravindra","year":"2023","unstructured":"Ravindra VM, Schmidt MH (2023) Spinal meningiomas: Diagnosis, surgical Management, and adjuvant Therapies, (in eng). Neurosurg Clin N Am 34(3):425\u2013435. https:\/\/doi.org\/10.1016\/j.nec.2023.02.007","journal-title":"Neurosurg Clin N Am"},{"issue":"11","key":"4151_CR8","doi-asserted-by":"publisher","first-page":"1821","DOI":"10.1093\/neuonc\/noab150","volume":"23","author":"R Goldbrunner","year":"2021","unstructured":"Goldbrunner R et al (2021) EANO guideline on the diagnosis and management of meningiomas, (in eng). Neuro Oncol 23(11):1821\u20131834. https:\/\/doi.org\/10.1093\/neuonc\/noab150","journal-title":"Neuro Oncol"},{"key":"4151_CR9","doi-asserted-by":"publisher","unstructured":"Tredway TL, Santiago P, Hrubes MR, Song JK, Christie SD, Fessler RG (2006) Minimally invasive resection of intradural-extramedullary spinal neoplasms, (in eng), Neurosurgery, vol. 58, no. 1 Suppl, pp. ONS52-8; discussion ONS52-8, Feb https:\/\/doi.org\/10.1227\/01.neu.0000192661.08192.1c","DOI":"10.1227\/01.neu.0000192661.08192.1c"},{"issue":"2","key":"4151_CR10","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.ejrad.2003.10.021","volume":"50","author":"JW Van Goethem","year":"2004","unstructured":"Van Goethem JW, van den Hauwe L, Ozsarlak O, De Schepper AM, Parizel PM (2004) Spinal tumors, (in eng). Eur J Radiol 50(2):159\u201376. https:\/\/doi.org\/10.1016\/j.ejrad.2003.10.021","journal-title":"Eur J Radiol"},{"issue":"3","key":"4151_CR11","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.clineuro.2008.10.018","volume":"111","author":"C Saraceni","year":"2009","unstructured":"Saraceni C, Harrop JS (2009) Spinal meningioma: chronicles of contemporary neurosurgical diagnosis and management, (in eng). Clin Neurol Neurosurg 111(3):221\u20136. https:\/\/doi.org\/10.1016\/j.clineuro.2008.10.018","journal-title":"Clin Neurol Neurosurg"},{"issue":"2","key":"4151_CR12","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1227\/00006123-198908000-00001","volume":"25","author":"CL Solero","year":"1989","unstructured":"Solero CL et al (1989) Spinal meningiomas: review of 174 operated cases, (in eng). Neurosurgery\u00a025(2):153\u201360","journal-title":"Neurosurgery"},{"issue":"5","key":"4151_CR13","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1080\/02688697.2019.1638886","volume":"34","author":"F Maiuri","year":"2020","unstructured":"Maiuri F, De Caro MDB, de Divitiis O, Guadagno E, Mariniello G (Oct2020) Recurrence of spinal meningiomas: analysis of the risk factors, (in eng). Br J Neurosurg 34(5):569\u2013574. https:\/\/doi.org\/10.1080\/02688697.2019.1638886","journal-title":"Br J Neurosurg"},{"issue":"Suppl 3","key":"4151_CR14","doi-asserted-by":"publisher","first-page":"iii73","DOI":"10.1093\/noajnl\/vdae123","volume":"6","author":"D Deska-Gauthier","year":"2024","unstructured":"Deska-Gauthier D et al (2024) Clinical, molecular, and genetic features of spinal meningiomas, (in eng). Neurooncol Adv 6(Suppl 3):iii73-iii82. https:\/\/doi.org\/10.1093\/noajnl\/vdae123","journal-title":"Neurooncol Adv"},{"issue":"5","key":"4151_CR15","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1007\/s00401-022-02504-6","volume":"144","author":"FL Ricklefs","year":"2022","unstructured":"Ricklefs FL et al (Nov 2022) Genetic and epigenetic profiling identifies two distinct classes of spinal meningiomas, (in eng). Acta Neuropathol 144(5):1057\u20131059. https:\/\/doi.org\/10.1007\/s00401-022-02504-6","journal-title":"Acta Neuropathol"},{"issue":"5","key":"4151_CR16","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1007\/s00401-022-02474-9","volume":"144","author":"L Hua","year":"2022","unstructured":"Hua L et al (2022) Two predominant molecular subtypes of spinal meningioma: thoracic NF2-mutant tumors strongly associated with female sex, and cervical AKT1-mutant tumors originating ventral to the spinal cord, (in eng). Acta Neuropathol 144(5):1053\u20131055 https:\/\/doi.org\/10.1007\/s00401-022-02474-9","journal-title":"Acta Neuropathol"},{"issue":"6","key":"4151_CR17","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1007\/s00401-016-1545-1","volume":"131","author":"DN Louis","year":"2016","unstructured":"Louis DN et al (2016) The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary, (in eng). Acta Neuropathol 131(6):803\u201320. https:\/\/doi.org\/10.1007\/s00401-016-1545-1","journal-title":"Acta Neuropathol"},{"key":"4151_CR18","doi-asserted-by":"publisher","unstructured":"Gull HH et al (2022) Spinal Meningioma Surgery through the Ages-Single-Center Experience over Three Decades, (in eng). Medicina (Kaunas) 58(11) https:\/\/doi.org\/10.3390\/medicina58111549","DOI":"10.3390\/medicina58111549"},{"key":"4151_CR19","doi-asserted-by":"publisher","first-page":"44","DOI":"10.11604\/pamj.2022.43.44.19808","volume":"43","author":"TA Oyemolade","year":"2022","unstructured":"Oyemolade TA, Adeolu AA, Malomo AO, Shokunbi MT, Salami AA (2022) Spinal meningioma: clinical profile and outcome of surgical management. Pan Afr Med J 43:44. https:\/\/doi.org\/10.11604\/pamj.2022.43.44.19808","journal-title":"Pan Afr Med J"},{"issue":"6","key":"4151_CR20","doi-asserted-by":"publisher","first-page":"979","DOI":"10.5137\/1019-5149.Jtn.22416-17.2","volume":"28","author":"B Ucler","year":"2018","unstructured":"Ucler B, Hergunsel S, Ozturk S, Kozan and M. Kaplan (2018) Simpson grade 2 resection and tumor recurrence in ventrally located spinal meningiomas. Turk Neurosurg 28(6):979\u2013982. https:\/\/doi.org\/10.5137\/1019-5149.Jtn.22416-17.2","journal-title":"Turk Neurosurg"},{"key":"4151_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/978-3-031-29750-2_1","volume":"1416","author":"B Krischek","year":"2023","unstructured":"Krischek B, Goldbrunner R (2023) Paradigm Shift in the Treatment of Meningiomas, (in eng). Adv Exp Med Biol 1416:1\u20134. https:\/\/doi.org\/10.1007\/978-3-031-29750-2_1","journal-title":"Adv Exp Med Biol"},{"issue":"9","key":"4151_CR22","doi-asserted-by":"publisher","first-page":"e383","DOI":"10.1016\/S1470-2045(16)30321-7","volume":"19","author":"R Goldbrunner","year":"2016","unstructured":"Goldbrunner R et al (2016) EANO guidelines for the diagnosis and treatment of meningiomas, (in eng). Lancet Oncol 17(9)e383-91. https:\/\/doi.org\/10.1016\/s1470-2045(16)30321-7","journal-title":"Lancet Oncol"},{"key":"4151_CR23","doi-asserted-by":"publisher","first-page":"106238","DOI":"10.1016\/j.clineuro.2020.106238","volume":"198","author":"LE Kwee","year":"2020","unstructured":"Kwee LE, Harhangi BS, Ponne GA, Kros JM, Dirven CMF, Dammers R (Nov 2020) Spinal meningiomas: treatment outcome and long-term follow-up, (in eng). Clin Neurol Neurosurg 198:106238. https:\/\/doi.org\/10.1016\/j.clineuro.2020.106238","journal-title":"Clin Neurol Neurosurg"},{"issue":"6","key":"4151_CR24","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1016\/S0090-3019(99)00153-6","volume":"52","author":"J Klekamp","year":"1999","unstructured":"Klekamp J, Samii M (1999) Surgical results for spinal meningiomas, (in eng). Surg Neurol 52(6):552\u201362. https:\/\/doi.org\/10.1016\/s0090-3019(99)00153-6","journal-title":"Surg Neurol"},{"issue":"1","key":"4151_CR25","doi-asserted-by":"publisher","first-page":"11630","DOI":"10.1038\/s41598-021-91225-z","volume":"11","author":"K Kobayashi","year":"2021","unstructured":"Kobayashi K et al (2021) Clinical features and prognostic factors in spinal meningioma surgery from a multicenter study, (in eng). Sci Rep 11(1):11630. https:\/\/doi.org\/10.1038\/s41598-021-91225-z","journal-title":"Sci Rep"},{"key":"4151_CR26","doi-asserted-by":"publisher","unstructured":"Jamilson Ara\u00fajo B, Pereira A, Nogueira de Almeida W, Silva Paiva P (2020) Henrique Pires de Aguiar, M. Jacobsen Teixeira, and S. Kazue Nagahashi Marie, Neuro-oncological features of spinal meningiomas: Systematic review, (in eng). Neurochirurgie\u00a066(1):41-44. https:\/\/doi.org\/10.1016\/j.neuchi.2019.09.027","DOI":"10.1016\/j.neuchi.2019.09.027"},{"issue":"1","key":"4151_CR27","doi-asserted-by":"publisher","first-page":"4050","DOI":"10.1038\/s41598-021-83712-0","volume":"11","author":"H Tominaga","year":"2021","unstructured":"Tominaga H, Kawamura I, Ijiri K, Yone K, Taniguchi N (2021) Surgical results of the resection of spinal meningioma with the inner layer of dura more than 10 years after surgery, (in eng). Sci Rep 11(1):4050. https:\/\/doi.org\/10.1038\/s41598-021-83712-0","journal-title":"Sci Rep"},{"key":"4151_CR28","doi-asserted-by":"publisher","unstructured":"Chotai S, Schwartz TH (2022) The Simpson Grading: Is It Still Valid? (in eng). Cancers (Basel) 14(8).\u00a0https:\/\/doi.org\/10.3390\/cancers14082007","DOI":"10.3390\/cancers14082007"},{"issue":"1","key":"4151_CR29","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1007\/s00701-024-05910-9","volume":"166","author":"M Simon","year":"2024","unstructured":"Simon M, Gousias K (2024) Grading meningioma resections: the Simpson classification and beyond. Acta Neurochir (Wien) 166(1):28. https:\/\/doi.org\/10.1007\/s00701-024-05910-9","journal-title":"Acta Neurochir (Wien)"},{"issue":"6","key":"4151_CR30","doi-asserted-by":"publisher","first-page":"1764","DOI":"10.3171\/2020.4.Jns20412","volume":"134","author":"DC Spille","year":"2021","unstructured":"Spille DC et al (2021) Risk of tumor recurrence in intracranial meningiomas: comparative analyses of the predictive value of the postoperative tumor volume and the Simpson classification. J Neurosurg 134(6):1764\u20131771. https:\/\/doi.org\/10.3171\/2020.4.Jns20412","journal-title":"J Neurosurg"},{"issue":"3","key":"4151_CR31","doi-asserted-by":"publisher","first-page":"1713","DOI":"10.1007\/s10143-020-01369-1","volume":"44","author":"B Brokinkel","year":"2021","unstructured":"Brokinkel B et al (2021) The Simpson grading: defining the optimal threshold for gross total resection in meningioma surgery. Neurosurg Rev 44(3):1713\u20131720. https:\/\/doi.org\/10.1007\/s10143-020-01369-1","journal-title":"Neurosurg Rev"},{"issue":"4","key":"4151_CR32","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1227\/00006123-199304000-00023","volume":"32","author":"PM Black","year":"1993","unstructured":"Black PM (1993) Meningiomas. Neurosurgery 32(4):643\u201357. https:\/\/doi.org\/10.1227\/00006123-199304000-00023","journal-title":"Neurosurgery"},{"issue":"4","key":"4151_CR33","first-page":"399","volume":"97","author":"P Bumrungrachpukdee","year":"2014","unstructured":"Bumrungrachpukdee P, Pruphetkaew N, Phukaoloun M, Pheunpathom N (2014) Recurrence of intracranial meningioma after surgery: analysis of influencing factors and outcome, (in eng). J Med Assoc Thai 97(4):399\u2013406","journal-title":"J Med Assoc Thai"},{"issue":"1","key":"4151_CR34","doi-asserted-by":"publisher","first-page":"18","DOI":"10.3171\/jns.1985.62.1.0018","volume":"62","author":"RO Mirimanoff","year":"1985","unstructured":"Mirimanoff RO, Dosoretz DE, Linggood RM, Ojemann RG, Martuza RL (1985) Meningioma: analysis of recurrence and progression following neurosurgical resection. J Neurosurg 62(1):18\u201324. https:\/\/doi.org\/10.3171\/jns.1985.62.1.0018","journal-title":"J Neurosurg"},{"key":"4151_CR35","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.wneu.2024.03.124","volume":"187","author":"G Garufi","year":"2024","unstructured":"Garufi G, Scalia G, Ricciardo G, Umana GE, Conti A, Cardali SM (2024) Spinal intramedullary meningiomas: a systematic review with a case illustration. World Neurosurg 187:11\u201318. https:\/\/doi.org\/10.1016\/j.wneu.2024.03.124","journal-title":"World Neurosurg"},{"key":"4151_CR36","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1186\/s40064-015-1110-8","volume":"4","author":"G Perven","year":"2015","unstructured":"Perven G, Entezami P, Gaudin D (2015) A rare case of intramedullary \u201cwhorling-sclerosing\u201d variant meningioma. Springerplus 4:318. https:\/\/doi.org\/10.1186\/s40064-015-1110-8","journal-title":"Springerplus"},{"key":"4151_CR37","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16071426","author":"DD Dang","year":"2024","unstructured":"Dang DD, Mugge LA, Awan OK, Gong AD, Fanous AA (2024) Spinal meningiomas: a comprehensive review and update on advancements in molecular characterization, diagnostics, surgical approach and technology, and alternative therapies. Cancers (Basel). https:\/\/doi.org\/10.3390\/cancers16071426","journal-title":"Cancers (Basel)"},{"issue":"3","key":"4151_CR38","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1007\/s11060-018-2993-3","volume":"140","author":"L Hua","year":"2018","unstructured":"Hua L et al (2018) Clinical and prognostic features of spinal meningioma: a thorough analysis from a single neurosurgical center. J Neurooncol 140(3):639\u2013647. https:\/\/doi.org\/10.1007\/s11060-018-2993-3","journal-title":"J Neurooncol"},{"issue":"6","key":"4151_CR39","doi-asserted-by":"publisher","first-page":"729","DOI":"10.3171\/2023.6.Spine23425","volume":"39","author":"J Driver","year":"2023","unstructured":"Driver J, Santagata S, Bi WL, Chi JH (2023) Genomic analysis of spinal meningiomas: correlation with histopathological grade. J Neurosurg Spine 39(6):729\u2013733. https:\/\/doi.org\/10.3171\/2023.6.Spine23425","journal-title":"J Neurosurg Spine"}],"container-title":["Neurosurgical Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-026-04151-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10143-026-04151-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-026-04151-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T17:43:14Z","timestamp":1781631794000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10143-026-04151-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,7]]},"references-count":39,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4151"],"URL":"https:\/\/doi.org\/10.1007\/s10143-026-04151-x","relation":{},"ISSN":["1437-2320"],"issn-type":[{"value":"1437-2320","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,7]]},"assertion":[{"value":"24 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 January 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 February 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was performed in compliance with the ethical principles of the Declaration of Helsinki (1964) and its later amendments, and with the regulations of the relevant institutional and national research committees. Ethical approval was obtained from the local Clinical Ethics Committee of our institution, Baden-Wuerttemberg, Germany (approval no. 191\/2021BO2 and amendment).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Tumor tissue and clinical data were only used if patient consent was available as defined by the Clinical Ethics Committee of the University of T\u00fcbingen.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"206"}}