{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:50:33Z","timestamp":1791352233518,"version":"4.3.1"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurosurg Rev"],"DOI":"10.1007\/s10143-026-04521-5","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:14:10Z","timestamp":1791342850000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Applications of acellular dermal matrix in spine surgery: A systematic review"],"prefix":"10.1007","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4422-2997","authenticated-orcid":false,"given":"Dong Hoon","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4896-8980","authenticated-orcid":false,"given":"Jin-Young","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2184-0044","authenticated-orcid":false,"given":"Jung-Woo","family":"Hur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6453-0439","authenticated-orcid":false,"given":"Jae Taek","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,7]]},"reference":[{"issue":"Sup1","key":"4521_CR1","first-page":"S21","volume":"31","author":"K Petrie","year":"2022","unstructured":"Petrie K, Cox CT, Becker BC, MacKay BJ (2022) Clinical applications of acellular dermal matrices: a review. J Wound Care 31(Sup1):S21\u2013S35","journal-title":"J Wound Care"},{"issue":"11","key":"4521_CR2","doi-asserted-by":"publisher","first-page":"2870","DOI":"10.3390\/biomedicines10112870","volume":"10","author":"M Gierek","year":"2022","unstructured":"Gierek M, \u0141abu\u015b W, Kitala D et al (2022) Human acellular dermal matrix in reconstructive surgery: a review. Biomedicines 10(11):2870","journal-title":"Biomedicines"},{"issue":"6","key":"4521_CR3","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1111\/iwj.12185","volume":"12","author":"RS Kirsner","year":"2015","unstructured":"Kirsner RS, Bohn G, Driver VR et al (2015) Human acellular dermal wound matrix: evidence and experience. Int Wound J 12(6):646\u2013654","journal-title":"Int Wound J"},{"issue":"7 Suppl","key":"4521_CR4","doi-asserted-by":"publisher","first-page":"5S","DOI":"10.1177\/1090820X11417576","volume":"31","author":"J Fosnot","year":"2011","unstructured":"Fosnot J, Kovach SJ, Serletti JM (2011) Acellular dermal matrix: general principles for the plastic surgeon. Aesthet Surg J 31(7 Suppl):5S\u201312S","journal-title":"Aesthet Surg J"},{"issue":"4","key":"4521_CR5","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/0305-4179(95)93866-I","volume":"21","author":"DJ Wainwright","year":"1995","unstructured":"Wainwright DJ (1995) Use of an acellular allograft dermal matrix (AlloDerm) in the management of full-thickness burns. Burns 21(4):243\u2013248","journal-title":"Burns"},{"issue":"2","key":"4521_CR6","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1097\/PRS.0000000000002331","volume":"138","author":"CA Salzberg","year":"2016","unstructured":"Salzberg CA, Ashikari AY, Berry C, Hunsicker LM (2016) Acellular dermal matrix-assisted direct-to-implant breast reconstruction and capsular contracture: a 13-year experience. Plast Reconstr Surg 138(2):329\u2013337","journal-title":"Plast Reconstr Surg"},{"issue":"6","key":"4521_CR7","first-page":"941e","volume":"147","author":"JM Broyles","year":"2021","unstructured":"Broyles JM, Abt NB, Shridharani SM, Bojovic B (2021) Acellular dermal matrix in implant-based breast reconstruction: a comparison of products. Plast Reconstr Surg 147(6):941e\u2013953e","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"4521_CR8","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1097\/SLA.0000000000001916","volume":"266","author":"JF Buell","year":"2017","unstructured":"Buell JF, Sigmon D, Ducoin C et al (2017) Initial experience with biologic polymer scaffold (Alloderm) in complex abdominal wall reconstruction. Ann Surg 266(1):185\u2013188","journal-title":"Ann Surg"},{"issue":"6","key":"4521_CR9","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1097\/SLA.0b013e3182849871","volume":"257","author":"MJ Rosen","year":"2013","unstructured":"Rosen MJ, Krpata DM, Ermlich B, Blatnik JA (2013) A 5-year clinical experience with single-staged repairs of infected and contaminated abdominal wall defects utilizing biologic mesh. Ann Surg 257(6):991\u2013996","journal-title":"Ann Surg"},{"issue":"10","key":"4521_CR10","doi-asserted-by":"publisher","first-page":"890","DOI":"10.12968\/jowc.2021.30.11.890","volume":"30","author":"HS Shim","year":"2021","unstructured":"Shim HS, Park KS, Kim SW (2021) Preventing postoperative adhesions after hand tendon repair using acellular dermal matrix. J Wound Care 30(10):890\u2013895","journal-title":"J Wound Care"},{"issue":"3","key":"4521_CR11","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1097\/00006534-200103000-00016","volume":"107","author":"BL Eppley","year":"2001","unstructured":"Eppley BL (2001) Experimental assessment of the revascularization of acellular human dermis for soft-tissue augmentation. Plast Reconstr Surg 107(3):757\u2013762","journal-title":"Plast Reconstr Surg"},{"issue":"4","key":"4521_CR12","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1227\/00006123-199604000-00053","volume":"38","author":"JS Ross","year":"1996","unstructured":"Ross JS, Robertson JT, Frederickson RC et al (1996) Association between peridural scar and recurrent radicular pain after lumbar discectomy: magnetic resonance evaluation. Neurosurgery 38(4):855\u2013863","journal-title":"Neurosurgery"},{"key":"4521_CR13","first-page":"277","volume":"8","author":"L Manchikanti","year":"1998","unstructured":"Manchikanti L, Bakhit CE, Pampati V (1998) The role of epidurography in caudal neuroplasty. Pain Digest 8:277\u2013281","journal-title":"Pain Digest"},{"issue":"22","key":"4521_CR14","doi-asserted-by":"publisher","first-page":"2453","DOI":"10.1097\/00007632-200211150-00007","volume":"27","author":"R Bazaz","year":"2002","unstructured":"Bazaz R, Lee MJ, Yoo JU (2002) Incidence of dysphagia after anterior cervical spine surgery: a prospective study. Spine 27(22):2453\u20132458","journal-title":"Spine"},{"issue":"13","key":"4521_CR15","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.1097\/01.BRS.0000129100.59913.EA","volume":"29","author":"CA Smith-Hammond","year":"2004","unstructured":"Smith-Hammond CA, New KC, Pietrobon R et al (2004) Prospective analysis of incidence and risk factors of dysphagia in spine surgery patients. Spine 29(13):1441\u20131446","journal-title":"Spine"},{"issue":"9 Suppl","key":"4521_CR16","doi-asserted-by":"publisher","first-page":"S76","DOI":"10.1097\/BRS.0b013e3181d81a96","volume":"35","author":"LH Riley","year":"2010","unstructured":"Riley LH, Vaccaro AR, Dettori JR, Hashimoto R (2010) Postoperative dysphagia in anterior cervical spine surgery. Spine 35(9 Suppl):S76\u2013S85","journal-title":"Spine"},{"issue":"4","key":"4521_CR17","first-page":"533","volume":"17","author":"JY Lee","year":"2008","unstructured":"Lee JY, Ebel H, Friese M et al (2008) Influence of human fibroblast-derived matrix on epidural fibrosis. Eur Spine J 17(4):533\u2013541","journal-title":"Eur Spine J"},{"issue":"11","key":"4521_CR18","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.1002\/bjs.7657","volume":"98","author":"BW Hellebrekers","year":"2011","unstructured":"Hellebrekers BW, Kooistra T (2011) Pathogenesis of postoperative adhesion formation. Br J Surg 98(11):1503\u20131516","journal-title":"Br J Surg"},{"issue":"6","key":"4521_CR19","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.1097\/00006123-200006000-00020","volume":"46","author":"WL Warren","year":"2000","unstructured":"Warren WL, Medary MB, Dureza CD et al (2000) Dural repair using acellular human dermis: experience with 200 cases: technique assessment. Neurosurgery 46(6):1391\u20131396","journal-title":"Neurosurgery"},{"issue":"1","key":"4521_CR20","first-page":"57","volume":"21","author":"JH Park","year":"2020","unstructured":"Park JH, Lee D et al (2020) A method to prevent cerebrospinal fluid leakage: reinforcing acellular dermal matrix. Arch Craniofac Surg 21(1):57\u201360","journal-title":"Arch Craniofac Surg"},{"issue":"8","key":"4521_CR21","doi-asserted-by":"publisher","first-page":"E563","DOI":"10.1097\/BRS.0b013e3181f4a6bb","volume":"36","author":"R Gill","year":"2011","unstructured":"Gill R, Kinsella CR Jr, Lin AY et al (2011) Acellular dermal matrix in the treatment and prevention of exposed vertical expandable prosthetic titanium ribs. Spine 36(8):E563\u2013E567","journal-title":"Spine"},{"issue":"5","key":"4521_CR22","doi-asserted-by":"publisher","first-page":"778","DOI":"10.14444\/7111","volume":"14","author":"OM Al Jammal","year":"2020","unstructured":"Al Jammal OM, Wali AR, Lewis CS et al (2020) Management of giant sacral pseudomeningocele in revision spine surgery. Int J Spine Surg 14(5):778\u2013784","journal-title":"Int J Spine Surg"},{"issue":"7","key":"4521_CR23","doi-asserted-by":"publisher","first-page":"2387","DOI":"10.1097\/00006534-200006000-00012","volume":"105","author":"WK Miles","year":"2000","unstructured":"Miles WK, Chang DW, Kroll SS et al (2000) Reconstruction of large sacral defects following total sacrectomy. Plast Reconstr Surg 105(7):2387\u20132394","journal-title":"Plast Reconstr Surg"},{"key":"4521_CR24","doi-asserted-by":"publisher","first-page":"n71","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71","journal-title":"BMJ"},{"key":"4521_CR25","doi-asserted-by":"publisher","first-page":"i4919","DOI":"10.1136\/bmj.i4919","volume":"355","author":"JA Sterne","year":"2016","unstructured":"Sterne JA, Hern\u00e1n MA, Reeves BC et al (2016) ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ 355:i4919","journal-title":"BMJ"},{"issue":"10","key":"4521_CR26","first-page":"2127","volume":"18","author":"Z Munn","year":"2020","unstructured":"Munn Z, Barker TH, Moola S et al (2020) Methodological quality of case series studies: an introduction to the JBI critical appraisal tool. JBI Evid Synth 18(10):2127\u20132133","journal-title":"JBI Evid Synth"},{"issue":"7650","key":"4521_CR27","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","volume":"336","author":"GH Guyatt","year":"2008","unstructured":"Guyatt GH, Oxman AD, Vist GE et al (2008) GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 336(7650):924\u2013926","journal-title":"BMJ"},{"issue":"6","key":"4521_CR28","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.3390\/medicina62061163","volume":"62","author":"DH Kim","year":"2026","unstructured":"Kim DH, Hur JW, Hong JT (2026) Effect of reprocessed micronized acellular dermal matrix on postoperative dysphagia after anterior cervical discectomy and fusion: a propensity score-matched study. Med (Kaunas) 62(6):1163. https:\/\/doi.org\/10.3390\/medicina62061163","journal-title":"Med (Kaunas)"},{"issue":"6","key":"4521_CR29","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1097\/01.sap.0000122651.12811.3d","volume":"52","author":"RL Agag","year":"2004","unstructured":"Agag RL, Granick MS, Omidi M, Catrambone J, Benevenia J (2004) Neurosurgical reconstruction with acellular cadaveric dermal matrix. Ann Plast Surg 52(6):571\u2013577","journal-title":"Ann Plast Surg"},{"issue":"2","key":"4521_CR30","doi-asserted-by":"publisher","first-page":"156","DOI":"10.3171\/2011.11.PEDS11249","volume":"9","author":"SM Hill","year":"2012","unstructured":"Hill SM, Elwood ET, Lin J (2012) Closure of meningomyelocele defects using acellular dermal matrix. J Neurosurg Pediatr 9(2):156\u2013160","journal-title":"J Neurosurg Pediatr"},{"issue":"2","key":"4521_CR31","first-page":"435","volume":"19","author":"JE Catrambone","year":"2008","unstructured":"Catrambone JE, Granick MS, Agag RL et al (2008) Repair of lumbosacral meningomyeloceles with acellular cadaveric dermal matrix. J Craniofac Surg 19(2):435\u2013438","journal-title":"J Craniofac Surg"},{"issue":"2","key":"4521_CR32","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1055\/s-2007-970556","volume":"17","author":"AS Ismail","year":"2007","unstructured":"Ismail AS, Costantino PD, Sen C (2007) Transnasal transsphenoidal endoscopic repair of CSF leakage using multilayer frontal pericranial flap. Skull Base 17(2):125\u2013131","journal-title":"Skull Base"},{"issue":"19","key":"4521_CR33","doi-asserted-by":"publisher","first-page":"3675","DOI":"10.1016\/j.biomaterials.2006.02.014","volume":"27","author":"TW Gilbert","year":"2006","unstructured":"Gilbert TW, Sellaro TL, Badylak SF (2006) Decellularization of tissues and organs. Biomaterials 27(19):3675\u20133683","journal-title":"Biomaterials"},{"issue":"6","key":"4521_CR34","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1016\/j.surg.2006.08.008","volume":"140","author":"CP Lombardi","year":"2006","unstructured":"Lombardi CP, Raffaelli M, D\u2019Alatri L et al (2006) Voice and swallowing changes after thyroidectomy in patients without inferior laryngeal nerve injuries. Surgery 140(6):1026\u20131032","journal-title":"Surgery"},{"key":"4521_CR35","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1097\/00003086-200108000-00033","volume":"389","author":"SJ Bosacco","year":"2001","unstructured":"Bosacco SJ, Gardner MJ, Guille JT (2001) Evaluation and treatment of dural tears in lumbar spine surgery: a review. Clin Orthop Relat Res 389:238\u2013247","journal-title":"Clin Orthop Relat Res"},{"key":"4521_CR36","first-page":"387","volume":"26","author":"J Liao","year":"2023","unstructured":"Liao J, Li X, Fan Y (2023) Prevention strategies of postoperative adhesion in soft tissues by applying biomaterials. Bioact Mater 26:387\u2013412","journal-title":"Bioact Mater"},{"issue":"2","key":"4521_CR37","doi-asserted-by":"publisher","first-page":"251","DOI":"10.2106\/00004623-200402000-00006","volume":"86","author":"CC Edwards","year":"2004","unstructured":"Edwards CC, Karpitskaya Y, Cha C et al (2004) Accurate identification of adverse outcomes after cervical spine surgery. J Bone Joint Surg Am 86(2):251\u2013256","journal-title":"J Bone Joint Surg Am"},{"issue":"9","key":"4521_CR38","doi-asserted-by":"publisher","first-page":"e0273215","DOI":"10.1371\/journal.pone.0273215","volume":"17","author":"JK Kim","year":"2022","unstructured":"Kim JK, Lee CR, Kang SW et al (2022) Efficacy and safety of temperature-sensitive acellular dermal matrix in prevention of postoperative adhesion after thyroidectomy: a randomized, multicenter, double-blind, non-inferiority study. PLoS ONE 17(9):e0273215","journal-title":"PLoS ONE"},{"issue":"2","key":"4521_CR39","doi-asserted-by":"publisher","first-page":"71","DOI":"10.4174\/astr.2025.108.2.71","volume":"108","author":"YJ Lee","year":"2025","unstructured":"Lee YJ, Kim JK, Kang SW et al (2025) Efficacy and safety of acellular dermal matrix for prevention of postoperative adhesion after thyroidectomy: a multicenter randomized controlled trial. Ann Surg Treat Res 108(2):71\u201380","journal-title":"Ann Surg Treat Res"},{"issue":"7","key":"4521_CR40","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1097\/DSS.0000000000000410","volume":"41","author":"DY Kim","year":"2015","unstructured":"Kim DY, Kang SW, Kim DS et al (2015) Preventive effect of human acellular dermal matrix on post-thyroidectomy scars and adhesions: a randomized, double-blinded, controlled trial. Dermatol Surg 41(7):812\u2013820","journal-title":"Dermatol Surg"},{"issue":"5","key":"4521_CR41","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1097\/00024720-200210000-00004","volume":"15","author":"A Frempong-Boadu","year":"2002","unstructured":"Frempong-Boadu A, Houten JK, Osber B et al (2002) Swallowing and speech dysfunction in patients undergoing anterior cervical discectomy and fusion. J Spinal Disord Tech 15(5):362\u2013368","journal-title":"J Spinal Disord Tech"},{"issue":"2","key":"4521_CR42","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.spinee.2006.02.024","volume":"7","author":"MJ Lee","year":"2007","unstructured":"Lee MJ, Bazaz R, Furey CG, Yoo J (2007) Risk factors for dysphagia after anterior cervical spine surgery: a two-year prospective cohort study. Spine J 7(2):141\u2013147","journal-title":"Spine J"},{"issue":"3","key":"4521_CR43","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1007\/s11999-010-1731-8","volume":"469","author":"JA Rihn","year":"2011","unstructured":"Rihn JA, Kane J, Albert TJ, Vaccaro AR, Hilibrand AS (2011) What is the incidence and severity of dysphagia after anterior cervical surgery? Clin Orthop Relat Res 469(3):658\u2013665","journal-title":"Clin Orthop Relat Res"},{"key":"4521_CR44","doi-asserted-by":"publisher","first-page":"19935","DOI":"10.1038\/s41598-021-97919-8","volume":"11","author":"HW Yu","year":"2021","unstructured":"Yu HW, Lee D, Lee K et al (2021) Effect of an anti-adhesion agent on vision-based assessment of cervical adhesions after thyroid surgery: randomized, placebo-controlled trial. Sci Rep 11:19935","journal-title":"Sci Rep"},{"issue":"4","key":"4521_CR45","doi-asserted-by":"publisher","first-page":"e28630","DOI":"10.1097\/MD.0000000000028630","volume":"101","author":"YJ Lee","year":"2022","unstructured":"Lee YJ, Ryoo HJ, Shim HS (2022) Prevention of postoperative adhesions after flexor tendon repair with acellular dermal matrix: a randomized controlled trial. Med (Baltim) 101(4):e28630","journal-title":"Med (Baltim)"}],"container-title":["Neurosurgical Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-026-04521-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10143-026-04521-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10143-026-04521-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:02:04Z","timestamp":1791349324000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10143-026-04521-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,7]]},"references-count":45,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4521"],"URL":"https:\/\/doi.org\/10.1007\/s10143-026-04521-5","relation":{},"ISSN":["1437-2320"],"issn-type":[{"value":"1437-2320","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,7]]},"assertion":[{"value":"6 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 September 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 October 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable (systematic review of published literature).","order":1,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent to participate\/ for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflicts of interest. Three authors (D.H.K., J.W.H., J.T.H.) are co-authors of one of the included studies (reference 25). To mitigate this conflict, all screening, data extraction, and risk-of-bias assessment for that study were performed independently by J.Y.K., who is not an author of that publication, and verified by an external methodologist. This is declared in the Methods.","order":3,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"CRD420261326660.","order":5,"name":"Ethics","label":"PROSPERO registration","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"601"}}