{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T12:53:28Z","timestamp":1753275208674},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2011,6,25]],"date-time":"2011-06-25T00:00:00Z","timestamp":1308960000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Clin Oncol"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1007\/s10147-011-0249-8","type":"journal-article","created":{"date-parts":[[2011,6,25]],"date-time":"2011-06-25T15:22:41Z","timestamp":1309015361000},"page":"774-777","source":"Crossref","is-referenced-by-count":12,"title":["Ileal perforation induced by acute radiation injury under gefitinib treatment"],"prefix":"10.1007","volume":"16","author":[{"given":"Takayuki","family":"Muraoka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunori","family":"Tsukuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Toyooka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunsuke","family":"Kagawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshio","family":"Naomoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuhiro","family":"Takemoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuniaki","family":"Katsui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susumu","family":"Kanazawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuho","family":"Maki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroko","family":"Masuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaaki","family":"Harada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Asano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minoru","family":"Naito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichiro","family":"Miyoshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,6,25]]},"reference":[{"key":"249_CR1","doi-asserted-by":"crossref","first-page":"S101","DOI":"10.1016\/j.ijrobp.2009.05.071","volume":"76","author":"BD Kavanagh","year":"2010","unstructured":"Kavanagh BD, Pan CC, Dawson LA et al (2010) Radiation dose-volume effects in the stomach and small bowel. Int J Radiat Oncol Biol Phys 76:S101\u2013S107","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"249_CR2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/j.1447-0756.2006.00382.x","volume":"32","author":"H Yamashita","year":"2006","unstructured":"Yamashita H, Nakagawa K, Tago M et al (2006) Small bowel perforation without tumor recurrence after radiotherapy for cervical carcinoma: report of seven cases. J Obstet Gynaecol Res 32:235\u2013242","journal-title":"J Obstet Gynaecol Res"},{"key":"249_CR3","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/s10147-006-0583-4","volume":"11","author":"T Mitsudomi","year":"2006","unstructured":"Mitsudomi T, Kosaka T, Yatabe Y (2006) Biological and clinical implications of EGFR mutations in lung cancer. Int J Clin Oncol 11:190\u2013198","journal-title":"Int J Clin Oncol"},{"key":"249_CR4","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1242\/jcs.03389","volume":"120","author":"J Yin","year":"2007","unstructured":"Yin J, Xu K, Zhang J et al (2007) Wound-induced ATP release and growth receptor activation in epithelial cells. J Cell Sci 120:815\u2013825","journal-title":"J Cell Sci"},{"key":"249_CR5","doi-asserted-by":"crossref","first-page":"4909","DOI":"10.1091\/mbc.E08-01-0097","volume":"7","author":"ER Block","year":"2008","unstructured":"Block ER, Klarlund JK (2008) Wounding sheets of epithelial cells activates the epidermal growth factor receptor through distinct short- and long-range mechanisms. Mol Biol Cell 7:4909\u20134917","journal-title":"Mol Biol Cell"},{"key":"249_CR6","doi-asserted-by":"crossref","first-page":"303","DOI":"10.2741\/A428","volume":"4","author":"MK Jones","year":"1999","unstructured":"Jones MK, Tomikawa M, Mohajer B et al (1999) Gastrointestinal mucosal regeneration: role of growth factors. Front Biosci 4:303\u2013309","journal-title":"Front Biosci"},{"key":"249_CR7","doi-asserted-by":"crossref","unstructured":"Kitagawa K, Hamada Y, Kato Y et al (2004) Epidermal growth factor and interleukin-1\u03b2 synergistically stimulate the production of nitric oxide in rat intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 287:1188\u20131193","DOI":"10.1152\/ajpgi.00254.2004"},{"key":"249_CR8","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1152\/ajpgi.00149.2004","volume":"287","author":"GM Myhre","year":"2004","unstructured":"Myhre GM, Toruner M, Abraham S et al (2004) Metalloprotease disintegrin-mediated ectodomain shedding of EGFR ligands promotes intestinal epithelial restitution. Am J Physiol Gastrointest Liver Physiol 287:1213\u20131219","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"249_CR9","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1093\/annonc\/mdg250","volume":"14","author":"K Nakagawa","year":"2003","unstructured":"Nakagawa K, Tamura T, Negoro S et al (2003) Phase I pharmacokinetic trial of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor gefitinib (\u2018Iressa\u2019, ZD1839) in Japanese patients with solid malignant tumors. Ann Oncol 14:922\u2013930","journal-title":"Ann Oncol"},{"key":"249_CR10","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1111\/j.1349-7006.2009.01190.x","volume":"100","author":"HQ Zhuang","year":"2009","unstructured":"Zhuang HQ, Sun J, Yuan ZY et al (2009) Radiosensitizing effects of gefitinib at administration times in vitro. Cancer Sci 100:1520\u20131525","journal-title":"Cancer Sci"},{"key":"249_CR11","first-page":"25","volume":"60","author":"N Taira","year":"2006","unstructured":"Taira N, Doihara H, Oota T et al (2006) Gefitinib, an epidermal growth factor receptor blockade agent, shows additional or synergistic effects on the radiosensitivity of esophageal cancer cells in vitro. Acta Med Okayama 60:25\u201334","journal-title":"Acta Med Okayama"},{"key":"249_CR12","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1158\/1078-0432.CCR-07-1468","volume":"14","author":"CH Gow","year":"2008","unstructured":"Gow CH, Chien CR, Chang YL et al (2008) Radiotherapy in lung adenocarcinoma with brain metastasis: effects of activating epidermal growth factor mutations on clinical response. Clin Cancer Res 14:162\u2013168","journal-title":"Clin Cancer Res"}],"container-title":["International Journal of Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10147-011-0249-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10147-011-0249-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10147-011-0249-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,12]],"date-time":"2019-06-12T09:06:29Z","timestamp":1560330389000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10147-011-0249-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,25]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["249"],"URL":"https:\/\/doi.org\/10.1007\/s10147-011-0249-8","relation":{},"ISSN":["1341-9625","1437-7772"],"issn-type":[{"value":"1341-9625","type":"print"},{"value":"1437-7772","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,6,25]]}}}