{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:24:37Z","timestamp":1785842677205,"version":"3.56.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2012,2,7]],"date-time":"2012-02-07T00:00:00Z","timestamp":1328572800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Clin Oncol"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1007\/s10147-012-0379-7","type":"journal-article","created":{"date-parts":[[2012,2,6]],"date-time":"2012-02-06T07:00:33Z","timestamp":1328511633000},"page":"314-320","source":"Crossref","is-referenced-by-count":11,"title":["Definitive radiation therapy for invasive carcinoma of the vagina: impact of high-dose rate intracavitary brachytherapy"],"prefix":"10.1007","volume":"18","author":[{"given":"Tetsuo","family":"Nonaka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobutaka","family":"Mizoguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Onose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisamori","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,2,7]]},"reference":[{"issue":"5","key":"379_CR1","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1002\/(SICI)1097-0142(19980901)83:5<1033::AID-CNCR30>3.0.CO;2-6","volume":"83","author":"WT Creasman","year":"1998","unstructured":"Creasman WT, Phillips JL, Menck HR (1998) The National Cancer Data Base report on cancer of the vagina. Cancer 83(5):1033\u20131040","journal-title":"Cancer"},{"issue":"Suppl 1","key":"379_CR2","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0020-7292(03)90114-7","volume":"83","author":"U Beller","year":"2003","unstructured":"Beller U, Maisonneuve P, Benedet JL et al (2003) Carcinoma of the vagina. Int J Gynaecol Obstet 83(Suppl 1):27\u201339","journal-title":"Int J Gynaecol Obstet"},{"issue":"3","key":"379_CR3","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0020-7292(99)00070-3","volume":"65","author":"S Pecorelli","year":"1999","unstructured":"Pecorelli S, Benedet JL, Creasman WT et al (1999) FIGO staging of gynecologic cancer. 1994\u20131997 FIGO Committee on Gynecologic Oncology. International Federation of Gynecology and Obstetrics. Int J Gynaecol Obstet 65(3):243\u2013249","journal-title":"Int J Gynaecol Obstet"},{"key":"379_CR4","first-page":"1657","volume-title":"Perez and Brady\u2019s principles and practice of radiation oncology","author":"HR Cardenes","year":"2008","unstructured":"Cardenes HR, Perez CA (2008) Vagina. In: Halperin EC, Perez CA, Brady LW (eds) Perez and Brady\u2019s principles and practice of radiation oncology, 5th edn. Lippincott Williams and Wilkins, Philadelphia, pp 1657\u20131681","edition":"5"},{"key":"379_CR5","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/978-3-540-77385-6_26","volume-title":"Radiation oncology: an evidence-based approach","author":"HA Gay","year":"2008","unstructured":"Gay HA, Allison RR (2008) Vaginal cancer. In: Lu JJ, Brady LW (eds) Radiation oncology: an evidence-based approach. Springer, Berlin, pp 383\u2013395"},{"issue":"1","key":"379_CR6","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.ijrobp.2004.09.032","volume":"62","author":"SJ Frank","year":"2005","unstructured":"Frank SJ, Jhingran A, Levenback C et al (2005) Definitive radiation therapy for squamous cell carcinoma of the vagina. Int J Radiat Oncol Biol Phys 62(1):138\u2013147","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"379_CR7","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1006\/gyno.1993.1248","volume":"51","author":"PJ Nanavati","year":"1993","unstructured":"Nanavati PJ, Fanning J, Hilgers RD et al (1993) High-dose-rate brachytherapy in primary stage I and II vaginal cancer. Gynecol Oncol 51:67\u201371","journal-title":"Gynecol Oncol"},{"key":"379_CR8","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1080\/j.1600-0412.2001.080004355.x","volume":"80","author":"H Kucera","year":"2001","unstructured":"Kucera H, Mock U, Knocke TH et al (2001) Radiotherapy alone for invasive vaginal cancer: outcome with intracavitary high dose rate brachytherapy versus conventional low dose rate brachytherapy. Acta Obstet Gynecol Scand 80:355\u2013360","journal-title":"Acta Obstet Gynecol Scand"},{"key":"379_CR9","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","volume":"53","author":"EL Kaplan","year":"1958","unstructured":"Kaplan EL, Meier P (1958) Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457\u2013481","journal-title":"J Am Stat Assoc"},{"key":"379_CR10","unstructured":"Cancer Therapy Evaluation Program (2010) Common Terminology Criteria for Adverse Events (CTCAE) v4.0. http:\/\/ctep.cancer.gov\/protocolDevelopment\/electronic_applications\/ctc.htm#ctc_40 . Accessed 30 June 2011"},{"issue":"1","key":"379_CR11","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0360-3016(98)00530-6","volume":"44","author":"CA Perez","year":"1999","unstructured":"Perez CA, Grigsby PW, Garipagaoglu M et al (1999) Factors affecting long-term outcome of irradiation in carcinoma of the vagina. Int J Radiat Oncol Biol Phys 44(1):37\u201345","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"379_CR12","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/0360-3016(95)02394-1","volume":"35","author":"V Chyle","year":"1996","unstructured":"Chyle V, Zagars GK, Wheeler JA et al (1996) Definitive radiotherapy for carcinoma of the vagina: outcome and prognostic factors. Int J Radiat Oncol Biol Phys 35:891\u2013905","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"379_CR13","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/0360-3016(91)90747-R","volume":"21","author":"S Reddy","year":"1991","unstructured":"Reddy S, Saxena VS, Reddy S et al (1991) Results of radiotherapeutic management of primary carcinoma of the vagina. Int J Radiat Oncol Biol Phys 21:1041\u20131044","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"379_CR14","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0360-3016(99)00360-0","volume":"46","author":"S Pingley","year":"2000","unstructured":"Pingley S, Shrivastava SK, Sarin R et al (2000) Primary carcinoma of the vagina: TATA Memorial Hospital experience. Int J Radiat Oncol Biol Phys 46:101\u2013108","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"3","key":"379_CR15","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1006\/gyno.1995.1077","volume":"56","author":"P Kirkbride","year":"1995","unstructured":"Kirkbride P, Fyles A, Rawlings GA et al (1995) Carcinoma of the vagina\u2014experience at the Princess Margaret Hospital (1974\u20131989). Gynecol Oncol 56(3):435\u2013443","journal-title":"Gynecol Oncol"},{"issue":"6","key":"379_CR16","first-page":"862","volume":"44","author":"CA Perez","year":"1974","unstructured":"Perez CA, Arneson AN, Dehner LP et al (1974) Radiation therapy in carcinoma of the vagina. Obstet Gynecol 44(6):862\u2013872","journal-title":"Obstet Gynecol"},{"issue":"4","key":"379_CR17","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S0360-3016(97)00924-3","volume":"40","author":"I Ogino","year":"1998","unstructured":"Ogino I, Kitamura T, Okajima H et al (1998) High-dose-rate intracavitary brachytherapy in the management of cervical and vaginal intraepithelial neoplasia. Int J Radiat Oncol Biol Phys 40(4):881\u2013887","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"4","key":"379_CR18","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1002\/1097-0142(20010215)91:4<758::AID-CNCR1062>3.0.CO;2-U","volume":"91","author":"KS Tewari","year":"2001","unstructured":"Tewari KS, Cappuccini F, Puthawala AA et al (2001) Primary invasive carcinoma of the vagina: treatment with interstitial brachytherapy. Cancer 91(4):758\u2013770","journal-title":"Cancer"},{"issue":"1","key":"379_CR19","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/j.1048-891x.2004.014066.x","volume":"14","author":"JL Dalrymple","year":"2004","unstructured":"Dalrymple JL, Russell AH, Lee SW et al (2004) Chemoradiation for primary invasive squamous carcinoma of the vagina. Int J Gynecol Cancer 14(1):110\u2013117","journal-title":"Int J Gynecol Cancer"},{"issue":"4","key":"379_CR20","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s10147-007-0758-7","volume":"13","author":"T Nashiro","year":"2008","unstructured":"Nashiro T, Yagi C, Hirakawa M et al (2008) Concurrent chemoradiation for locally advanced squamous cell carcinoma of the vagina: case series and literature review. Int J Clin Oncol 13(4):335\u2013339","journal-title":"Int J Clin Oncol"},{"issue":"15","key":"379_CR21","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1056\/NEJM199904153401503","volume":"340","author":"HM Keys","year":"1999","unstructured":"Keys HM, Bundy BN, Stehman FB et al (1999) Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N Engl J Med 340(15):1154\u20131161 (Erratum in: N Engl J Med 1999;341(9):708)","journal-title":"N Engl J Med"},{"issue":"15","key":"379_CR22","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1056\/NEJM199904153401501","volume":"340","author":"M Morris","year":"1999","unstructured":"Morris M, Eifel PJ, Lu J et al (1999) Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer. N Engl J Med 340(15):1137\u20131143","journal-title":"N Engl J Med"},{"issue":"15","key":"379_CR23","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1056\/NEJM199904153401502","volume":"340","author":"PG Rose","year":"1999","unstructured":"Rose PG, Bundy BN, Watkins EB et al (1999) Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer. N Engl J Med 340(15):1144\u20131153 (Erratum in: N Engl J Med 341(9):708)","journal-title":"N Engl J Med"},{"issue":"5","key":"379_CR24","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1200\/JCO.1999.17.5.1339","volume":"17","author":"CW Whitney","year":"1999","unstructured":"Whitney CW, Sause W, Bundy BN et al (1999) Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: a Gynecologic Oncology Group and Southwest Oncology Group study. J Clin Oncol 17(5):1339\u20131348","journal-title":"J Clin Oncol"},{"issue":"2","key":"379_CR25","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/0090-8258(89)90029-2","volume":"35","author":"RD Alvarez","year":"1989","unstructured":"Alvarez RD, Soong SJ, Kinney WK et al (1989) Identification of prognostic factors and risk groups in patients found to have nodal metastasis at the time of radical hysterectomy for early-stage squamous carcinoma of the cervix. Gynecol Oncol 35(2):130\u2013135","journal-title":"Gynecol Oncol"},{"issue":"4","key":"379_CR26","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/0360-3016(95)00204-5","volume":"33","author":"T Toita","year":"1995","unstructured":"Toita T, Nakano M, Higashi M et al (1995) Prognostic value of cervical size and pelvic lymph node status assessed by computed tomography for patients with uterine cervical cancer treated by radical radiation therapy. Int J Radiat Oncol Biol Phys 33(4):843\u2013849","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["International Journal of Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10147-012-0379-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10147-012-0379-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10147-012-0379-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T10:37:26Z","timestamp":1559126246000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10147-012-0379-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2,7]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["379"],"URL":"https:\/\/doi.org\/10.1007\/s10147-012-0379-7","relation":{},"ISSN":["1341-9625","1437-7772"],"issn-type":[{"value":"1341-9625","type":"print"},{"value":"1437-7772","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,2,7]]}}}