{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:37:04Z","timestamp":1791311824322,"version":"4.3.1"},"reference-count":84,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Clin Oncol"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1007\/s10147-014-0689-z","type":"journal-article","created":{"date-parts":[[2014,3,30]],"date-time":"2014-03-30T20:36:53Z","timestamp":1396211813000},"page":"423-430","source":"Crossref","is-referenced-by-count":207,"title":["Current status of oral cancer treatment strategies: surgical treatments for oral squamous cell carcinoma"],"prefix":"10.1007","volume":"19","author":[{"given":"Ken","family":"Omura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,4,1]]},"reference":[{"key":"689_CR1","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1007\/s10147-007-0756-9","volume":"13","author":"Y Ariyoshi","year":"2008","unstructured":"Ariyoshi Y, Shimahara M, Omura K et al (2008) Epidemiological study of malignant tumors in the oral and maxillofacial region: survey of member institutions of the Japanese Society of Oral and Maxillofacial Surgeons, 2002. Int J Clin Oncol 13:220\u2013228","journal-title":"Int J Clin Oncol"},{"key":"689_CR2","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1288\/00005537-198205000-00020","volume":"92","author":"WF McGuirt","year":"1982","unstructured":"McGuirt WF (1982) Panendoscopy as a screening examination for simultaneous primary tumors in head and neck cancer: a prospective sequential study and review of the literature. Laryngoscope 92:569\u2013576","journal-title":"Laryngoscope"},{"key":"689_CR3","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/j.1349-7006.1991.tb01743.x","volume":"82","author":"M Saikawa","year":"1991","unstructured":"Saikawa M, Ebihara S, Yoshizumi T et al (1991) Multiple primary cancers in patients with squamous cell carcinoma of the oral cavity. Jpn J Cancer Res 82:40\u201345","journal-title":"Jpn J Cancer Res"},{"key":"689_CR4","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1054\/ijom.2002.0313","volume":"32","author":"DN Sutton","year":"2003","unstructured":"Sutton DN, Brown JS, Rogers SN et al (2003) The prognostic implications of the surgical margin in the oral squamous cell carcinoma. Int J Oral Maxillofac Surg 32:30\u201334","journal-title":"Int J Oral Maxillofac Surg"},{"key":"689_CR5","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S0266-4356(03)00119-0","volume":"41","author":"J McMahon","year":"2003","unstructured":"McMahon J, O\u2019Brien CJ, Pathak I et al (2003) Influence of condition of surgical margins on local recurrence and disease-specific survival in oral and oropharyngeal cancer. Br J Oral Maxillofac Surg 41:224\u2013231","journal-title":"Br J Oral Maxillofac Surg"},{"key":"689_CR6","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/jso.20285","volume":"91","author":"RC Mistry","year":"2005","unstructured":"Mistry RC, Qureshi SS, Kumaran C (2005) Post-resection mucosal margin shrinkage in oral cancer: quantification and significance. J Surg Oncol 91:131\u2013133","journal-title":"J Surg Oncol"},{"key":"689_CR7","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1002\/hed.20269","volume":"27","author":"JD Meier","year":"2005","unstructured":"Meier JD, Oliver DA, Varvares MA (2005) Surgical margin determination in head and neck oncology: current clinical practice. The results of an International American Head and Neck Society Member Survey. Head Neck 27:952\u2013958","journal-title":"Head Neck"},{"key":"689_CR8","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S1079-2104(96)80326-X","volume":"81","author":"H Kurita","year":"1996","unstructured":"Kurita H, Kurashina K (1996) Vital staining with iodine solution in delineating the border of oral dysplastic lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 81:275\u2013280","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"689_CR9","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1007\/s10147-012-0450-4","volume":"18","author":"T Xiao","year":"2013","unstructured":"Xiao T, Kurita H, Shimane T et al (2013) Vital staining with iodine solution in oral cancer: iodine infiltration, cell proliferation, and glucose transporter 1. Int J Clin Oncol 18:792\u2013800","journal-title":"Int J Clin Oncol"},{"key":"689_CR10","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.oraloncology.2010.07.013","volume":"46","author":"M Petruzzi","year":"2010","unstructured":"Petruzzi M, Lucchese A, Baldoni E et al (2010) Use of Lugol\u2019s iodine in oral cancer diagnosis: an overview. Oral Oncol 46:811\u2013813","journal-title":"Oral Oncol"},{"key":"689_CR11","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1097\/00006534-199809010-00016","volume":"102","author":"DA Hidalgo","year":"1998","unstructured":"Hidalgo DA, Disa JD, Cordeiro PG et al (1998) A review of 716 consecutive free flaps for oncologic surgical defects: refinements in donor site selection and technique. Plast Reconstr Surg 102:722\u2013732","journal-title":"Plast Reconstr Surg"},{"key":"689_CR12","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s10147-012-0513-6","volume":"18","author":"M Sakuraba","year":"2013","unstructured":"Sakuraba M, Miyamoto S, Kimata Y et al (2013) Recent advances in reconstructive surgery: head and neck reconstruction. Int J Clin Oncol 18:561\u2013565","journal-title":"Int J Clin Oncol"},{"key":"689_CR13","doi-asserted-by":"crossref","first-page":"27","DOI":"10.5357\/koubyou.77.1_27","volume":"77","author":"M Kudoh","year":"2010","unstructured":"Kudoh M (2010) Longitudinal assessment of articulatory and masticatory functions following glossectomy for tongue carcinoma. Kokubyo Gakkai Zasshi 77:27\u201334","journal-title":"Kokubyo Gakkai Zasshi"},{"key":"689_CR14","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.oraloncology.2013.03.001","volume":"49","author":"L Lam","year":"2013","unstructured":"Lam L, Samman N (2013) Speech and swallowing following tongue cancer surgery and free flap reconstruction\u2014a systematic review. Oral Oncol 49:507\u2013524","journal-title":"Oral Oncol"},{"key":"689_CR15","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1097\/00005537-200305000-00024","volume":"113","author":"Y Kimata","year":"2003","unstructured":"Kimata Y, Sakuraba M, Hishinuma S et al (2003) Analysis of the relations between the shape of the reconstructed tongue and postoperative functions after subtotal or total glossectomy. Laryngoscope 113:905\u2013909","journal-title":"Laryngoscope"},{"key":"689_CR16","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1002\/hed.20804","volume":"30","author":"C Yanai","year":"2008","unstructured":"Yanai C, Kikutani T, Adachi M et al (2008) Functional outcome after total and subtotal glossectomy with free flap reconstruction. Head Neck 30:909\u2013918","journal-title":"Head Neck"},{"key":"689_CR17","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1001\/archotol.1983.00800160003001","volume":"109","author":"HF Biller","year":"1983","unstructured":"Biller HF, Lawson W, Baek SM (1983) Total glossectomy. A technique of reconstruction eliminating laryngectomy. Arch Otolaryngol 109:69\u201373","journal-title":"Arch Otolaryngol"},{"key":"689_CR18","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1097\/MLG.0b013e3180686590","volume":"117","author":"Y Fujimoto","year":"2007","unstructured":"Fujimoto Y, Hasegawa Y, Yamada H et al (2007) Swallowing function following extensive resection of oral or oropharyngeal cancer with laryngeal suspension and cricopharyngeal myotomy. Laryngoscope 117:1343\u20131348","journal-title":"Laryngoscope"},{"key":"689_CR19","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1002\/jso.2930100408","volume":"10","author":"HA McColl Jr","year":"1978","unstructured":"McColl HA Jr, Horwood J (1978) \u2018Localized\u2019 carcinoma of the mobile tongue and floor of mouth\u2014a lesion frequently misjudged and undertreated. J Surg Oncol 10:337\u2013345","journal-title":"J Surg Oncol"},{"key":"689_CR20","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1002\/(SICI)1097-0347(199708)19:5<400::AID-HED6>3.0.CO;2-3","volume":"19","author":"WL Hicks Jr","year":"1997","unstructured":"Hicks WL Jr, Lorre TR, Garcia RI et al (1997) Squamous cell carcinoma of the floor of mouth: a 20-year review. Head Neck 19:400\u2013405","journal-title":"Head Neck"},{"key":"689_CR21","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1097\/00006534-199505000-00010","volume":"95","author":"JB Boyd","year":"1995","unstructured":"Boyd JB, Mulholland RS, Davidson J et al (1995) The free flap and plate in oromandibular reconstruction: long-term review and indications. Plast Reconstr Surg 95:1018\u20131028","journal-title":"Plast Reconstr Surg"},{"key":"689_CR22","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S0194-5998(03)00480-7","volume":"129","author":"C Head","year":"2003","unstructured":"Head C, Alam D, Sercarz JA et al (2003) Microvascular flap reconstruction of the mandible: a comparison of bone grafts and bridging plates for restoration of mandibular continuity. Otolaryngol Head Neck Surg 129:48\u201354","journal-title":"Otolaryngol Head Neck Surg"},{"key":"689_CR23","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1097\/00006534-200111000-00018","volume":"108","author":"A Takushima","year":"2001","unstructured":"Takushima A, Harii K, Asato H et al (2001) Mandibular reconstruction using microvascular free flap: a statistical analysis of 178 cases. Plast Reconstr Surg 108:1555\u20131563","journal-title":"Plast Reconstr Surg"},{"key":"689_CR24","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.otot.2004.05.003","volume":"15","author":"SP Hao","year":"2004","unstructured":"Hao SP, Cheng MH (2004) Cancer of the buccal mucosa and retromolar trigone. Oper Tech Otolaryngol 15:239\u2013251","journal-title":"Oper Tech Otolaryngol"},{"key":"689_CR25","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1002\/micr.20223","volume":"26","author":"O Ozkan","year":"2006","unstructured":"Ozkan O, Mardini S, Chen HC et al (2006) Repair of buccal defects with anterolateral thigh flaps. Microsurgery 26:182\u2013189","journal-title":"Microsurgery"},{"key":"689_CR26","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1016\/j.ijom.2011.05.020","volume":"40","author":"WW Liu","year":"2011","unstructured":"Liu WW, Yang AK, Ou YD (2011) The harvesting and insetting of a chimeric anterolateral thigh flap to reconstruct through and through cheek defects. Int J Oral Maxillofac Surg 40:1421\u20131423","journal-title":"Int J Oral Maxillofac Surg"},{"key":"689_CR27","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1002\/cncr.21038","volume":"103","author":"WM Mendenhall","year":"2005","unstructured":"Mendenhall WM, Morris CG, Amdur RJ et al (2005) Retromolar trigone squamous cell carcinoma treated with radiotherapy alone or combined with surgery. Cancer 103:2320\u20132325","journal-title":"Cancer"},{"key":"689_CR28","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/S1368-8375(03)00103-9","volume":"39","author":"FM Genden","year":"2003","unstructured":"Genden FM, Ferito A, Shaha AR et al (2003) Management of cancer of the retromolar trigone. Oral Oncol 39:633\u2013637","journal-title":"Oral Oncol"},{"key":"689_CR29","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1002\/hed.2890100502","volume":"10","author":"AD McGregor","year":"1988","unstructured":"McGregor AD, MacDonald DG (1988) Routes of entry of squamous cell carcinoma to the mandible. Head Neck 10:294\u2013301","journal-title":"Head Neck"},{"key":"689_CR30","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/hed.2880130107","volume":"13","author":"Y Totsuka","year":"1991","unstructured":"Totsuka Y, Usui Y, Tei K et al (1991) Mandibular involvement by squamous cell carcinoma of the lower alveolus. Analysis and comparative study of histologic and radiologic features. Head Neck 13:40\u201350","journal-title":"Head Neck"},{"key":"689_CR31","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/0002-9610(91)90155-7","volume":"162","author":"MM Virag","year":"1991","unstructured":"Virag MM, Bunarevi\u0107 A, Aljinovi\u0107 N (1991) Recurrences of oral cancer due to discontinuous periosteal involvement. Am J Surg 162:388\u2013392","journal-title":"Am J Surg"},{"key":"689_CR32","doi-asserted-by":"crossref","first-page":"35","DOI":"10.5843\/jsot.16.35","volume":"16","author":"T Fujibayashi","year":"2004","unstructured":"Fujibayashi T (2004) Level of mandibular canal (LMC) criteria of lower gingival carcinomas and mode of mandibulectomy according to LMC criteria and bone invasion pattern. J Jpn Soc Oral Tumors 16:35\u201348","journal-title":"J Jpn Soc Oral Tumors"},{"key":"689_CR33","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/hed.2880130206","volume":"13","author":"Y Totsuka","year":"1991","unstructured":"Totsuka Y, Usui Y, Tei K et al (1991) Results of surgical treatment for squamous carcinoma of the lower alveolus: segmental vs marginal resection. Head Neck 13:114\u2013120","journal-title":"Head Neck"},{"key":"689_CR34","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/S0278-2391(97)90693-5","volume":"55","author":"RA Ord","year":"1997","unstructured":"Ord RA, Sarmadi M, Papadimitrou J (1997) A comparison of segmental and marginal bony resection for oral squamous cell carcinoma involving the mandible. J Oral Maxillofac Surg 55:470\u2013477","journal-title":"J Oral Maxillofac Surg"},{"key":"689_CR35","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1080\/000164800750000379","volume":"120","author":"M Politi","year":"2000","unstructured":"Politi M, Costa F, Robiony M et al (2000) Review of segmental and marginal resection of the mandible in patients with oral cancer. Acta Otolaryngol 120:569\u2013579","journal-title":"Acta Otolaryngol"},{"key":"689_CR36","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1001\/archotol.128.5.600","volume":"128","author":"MK Wax","year":"2002","unstructured":"Wax MK, Bascom DA, Myers LL (2002) Marginal mandibulectomy vs segmental mandibulectomy, indication and controversies. Arch Otolaryngol Head Neck Surg 128:600\u2013603","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"689_CR37","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.oraloncology.2004.12.002","volume":"41","author":"EM Genden","year":"2005","unstructured":"Genden EM, Rinaldo A, Jacobson A et al (2005) Management of mandibular invasion: when is a marginal mandibulectomy appropriate? Oral Oncol 41:776\u2013782","journal-title":"Oral Oncol"},{"key":"689_CR38","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/S0901-5027(03)90420-6","volume":"32","author":"CJ O\u2019Brien","year":"2003","unstructured":"O\u2019Brien CJ, Adams JR, McNeil EB et al (2003) Influence of bone invasion and extent of mandibular resection on local control of cancers of the oral cavity and oropharynx. Int J Oral Maxillofac Surg 32:492\u2013497","journal-title":"Int J Oral Maxillofac Surg"},{"key":"689_CR39","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1097\/MLG.0b013e31816422bb","volume":"118","author":"RS Patel","year":"2008","unstructured":"Patel RS, Dirven R, Clark JR et al (2008) The prognostic impact of extent of bone invasion and extent of bone resection in oral carcinoma. Laryngoscope 118:780\u2013785","journal-title":"Laryngoscope"},{"key":"689_CR40","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2214\/ajr.96.1.15","volume":"96","author":"AG Swearingen","year":"1966","unstructured":"Swearingen AG, McGraw JP, Palumbo VD (1966) Roentgenographic pathologic correlation of carcinoma of the gingival involving the mandible. Am J Roentogenol 96:15\u201318","journal-title":"Am J Roentogenol"},{"key":"689_CR41","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/00005537-200001000-00013","volume":"110","author":"RJ Wong","year":"2000","unstructured":"Wong RJ, Keel SB, Glynn RJ et al (2000) Histological pattern of mandibular invasion by oral squamous cell carcinoma. Laryngoscope 110:65\u201372","journal-title":"Laryngoscope"},{"key":"689_CR42","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1016\/j.joms.2005.05.321","volume":"63","author":"T Nomura","year":"2005","unstructured":"Nomura T, Shibahara T, Cui NH et al (2005) Patterns of mandibular invasion by gingival squamous cell carcinoma. J Oral Maxillofac Surg 63:1489\u20131493","journal-title":"J Oral Maxillofac Surg"},{"key":"689_CR43","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.joms.2003.09.014","volume":"62","author":"K Tei","year":"2004","unstructured":"Tei K, Totsuka Y, Iizuka T et al (2004) Marginal resection for carcinoma of the mandibular alveolus and gingiva where radiologically detected bone defects do not extend beyond the mandibular canal. J Oral Maxillofac Surg 62:834\u2013839","journal-title":"J Oral Maxillofac Surg"},{"key":"689_CR44","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1002\/hed.10031","volume":"23","author":"JW Werning","year":"2001","unstructured":"Werning JW, Byers RM, Novas MA et al (2001) Preoperative assessment for and outcomes of mandibular conservation surgery. Head Neck 23:1024\u20131030","journal-title":"Head Neck"},{"key":"689_CR45","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1001\/archotol.128.7.751","volume":"128","author":"KT Robbins","year":"2002","unstructured":"Robbins KT, Clayman G, Levine PA et al (2002) Neck dissection classification update: revisions proposed by the American Head and Neck Society and the American Academy of Otolaryngology\u2013Head and Neck Surgery. Arch Otolaryngol Head Neck Surg 128:751\u2013758","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"689_CR46","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S0194-5998(03)01582-1","volume":"129","author":"P Sheahan","year":"2003","unstructured":"Sheahan P, O\u2019Keane C, Sheahan JN et al (2003) Predictors of survival in early oral cancer. Otolaryngol Head Neck Surg 129:571\u2013576","journal-title":"Otolaryngol Head Neck Surg"},{"key":"689_CR47","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1445-2197.2005.03306.x","volume":"75","author":"MJ Veness","year":"2005","unstructured":"Veness MJ, Morgan GJ, Sathiyaseelan Y et al (2005) Anterior tongue cancer and the incidence of cervical lymph node metastases with increasing tumour thickness: should elective treatment to the neck be standard practice in all patients? ANZ J Surg 75:101\u2013105","journal-title":"ANZ J Surg"},{"key":"689_CR48","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.oraloncology.2009.10.005","volume":"46","author":"S Mark Taylor","year":"2010","unstructured":"Mark Taylor S, Drover C, Maceachern R et al (2010) Is preoperative ultrasonography accurate in measuring tumor thickness and predicting the incidence of cervical metastasis in oral cancer? Oral Oncol 46:38\u201341","journal-title":"Oral Oncol"},{"key":"689_CR49","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/hed.10130","volume":"24","author":"H Kurokawa","year":"2002","unstructured":"Kurokawa H, Yamashita Y, Takeda S et al (2002) Risk factors for late cervical lymph node metastases in patients with stage I or II carcinoma of the tongue. Head Neck 24:731\u2013736","journal-title":"Head Neck"},{"key":"689_CR50","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.otohns.2004.04.008","volume":"131","author":"A Sparano","year":"2004","unstructured":"Sparano A, Weinstein G, Chalian A et al (2004) Multivariate predictors of occult neck metastasis in early oral tongue cancer. Otolaryngol Head Neck Surg 131:472\u2013476","journal-title":"Otolaryngol Head Neck Surg"},{"key":"689_CR51","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1158\/1078-0432.CCR-0533-3","volume":"10","author":"SC Lim","year":"2004","unstructured":"Lim SC, Zhang S, Ishii G et al (2004) Predictive markers for late cervical metastasis in stage I and II invasive squamous cell carcinoma of the oral tongue. Clin Cancer Res 10:166\u2013172","journal-title":"Clin Cancer Res"},{"key":"689_CR52","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/jso.20546","volume":"94","author":"CY Chien","year":"2006","unstructured":"Chien CY, Su CY, Hwang CF et al (2006) High expressions of CD105 and VEGF in early oral cancer predict potential cervical metastasis. J Surg Oncol 94:413\u2013417","journal-title":"J Surg Oncol"},{"key":"689_CR53","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/hed.20482","volume":"29","author":"A Capote","year":"2007","unstructured":"Capote A, Escorial V, Mu\u00f1oz-Guerra MF et al (2007) Elective neck dissection in early-stage oral squamous cell carcinoma. Does it influence recurrence and survival ? Head Neck 29:3\u201311","journal-title":"Head Neck"},{"key":"689_CR54","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1067\/mhn.2001.116188","volume":"125","author":"FL Dias","year":"2001","unstructured":"Dias FL, Kligerman J, Matos de S\u00e1 G et al (2001) Elective neck dissection versus observation in stage I squamous cell carcinomas of the tongue and floor of the mouth. Otolaryngol Head Neck Surg 125:23\u201329","journal-title":"Otolaryngol Head Neck Surg"},{"key":"689_CR55","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.oraloncology.2005.06.018","volume":"42","author":"H Keski-Santti","year":"2006","unstructured":"Keski-Santti H, Atula T, T\u00f6rnwall J et al (2006) Elective neck treatment versus observation in patients with T1\/T2 N0 squamous cell carcinoma of oral tongue. Oral Oncol 42:96\u2013101","journal-title":"Oral Oncol"},{"key":"689_CR56","first-page":"536","volume":"31","author":"T Asakage","year":"2005","unstructured":"Asakage T, Kishimoto S, Saikawa M et al (2005) The standardization of neck dissection for tongue carcinoma. Jpn Head Neck Cancer 31:536\u2013540","journal-title":"Jpn Head Neck Cancer"},{"key":"689_CR57","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1001\/archotol.1994.01880310005001","volume":"120","author":"M Weiss","year":"1994","unstructured":"Weiss M, Harrison LB, Isaacs RS (1994) Use of decision analysis in planning a management strategy for the stage N0 neck. Arch Otolaryngol Head Neck Surg 120:699\u2013702","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"689_CR58","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0002-9610(99)00123-3","volume":"178","author":"C Majoufre","year":"1999","unstructured":"Majoufre C, Faucher A, Laroche C et al (1999) Supraomohyoid neck dissection in cancer of the oral cavity. Am J Surg 178:73\u201377","journal-title":"Am J Surg"},{"key":"689_CR59","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.amjsurg.2005.10.008","volume":"191","author":"S Yu","year":"2006","unstructured":"Yu S, Li J, Zhang W et al (2006) Efficacy of supraomohyoid neck dissection in patients with oral squamous cell carcinoma and negative neck. Am J Surg 191:94\u201399","journal-title":"Am J Surg"},{"key":"689_CR60","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/(SICI)1097-0347(199701)19:1<14::AID-HED3>3.0.CO;2-Y","volume":"19","author":"RM Byers","year":"1997","unstructured":"Byers RM, Weber RS, Andrews T et al (1997) Frequency and therapeutic implications of \u201cskip metastases\u201d in the neck from squamous carcinoma of the oral tongue. Head Neck 19:14\u201319","journal-title":"Head Neck"},{"key":"689_CR61","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.otohns.2005.09.025","volume":"134","author":"FL Dias","year":"2006","unstructured":"Dias FL, Lima RA, Kligerman J et al (2006) Relevance of skip metastases for squamous cell carcinoma of the oral tongue and the floor of the mouth. Otolaryngol Head Neck Surg 134:460\u2013465","journal-title":"Otolaryngol Head Neck Surg"},{"key":"689_CR62","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.bjoms.2008.06.001","volume":"47","author":"A Ferlito","year":"2009","unstructured":"Ferlito A, Silver CE, Rinaldo A (2009) Elective management of the neck in oral cavity squamous carcinoma: current concepts supported by prospective studies. Br J Oral Maxillofac Surg 47:5\u20139","journal-title":"Br J Oral Maxillofac Surg"},{"key":"689_CR63","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s00405-010-1364-2","volume":"268","author":"A Terada","year":"2011","unstructured":"Terada A, Hasegawa Y, Yatabe Y et al (2011) Follow-up after intraoperative sentinel node biopsy of N0 neck oral cancer patients. Eur Arch Otorhinolaryngol 268:429\u2013435","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"689_CR64","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1002\/lary.23383","volume":"122","author":"AE Melkane","year":"2012","unstructured":"Melkane AE, Mamelle G, Wycisk G et al (2012) Sentinel node biopsy in early oral squamous cell carcinomas: a 10-year experience. Laryngoscope 122:1782\u20131788","journal-title":"Laryngoscope"},{"key":"689_CR65","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1002\/hed.23017","volume":"35","author":"MA Broglie","year":"2013","unstructured":"Broglie MA, Haerle SK, Huber GF et al (2013) Occult metastases detected by sentinel node biopsy in patients with early oral and oropharyngeal squamous cell carcinomas: impact on survival. Head Neck 35:660\u2013666","journal-title":"Head Neck"},{"key":"689_CR66","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/0002-9610(87)90614-3","volume":"153","author":"CJ O\u2019Brien","year":"1987","unstructured":"O\u2019Brien CJ, Urist MM, Maddox WA (1987) Modified radical neck dissection. Terminology, technique, and indications. Am J Surg 153:310\u2013316","journal-title":"Am J Surg"},{"key":"689_CR67","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/(SICI)1097-0347(200005)22:3<207::AID-HED1>3.0.CO;2-9","volume":"22","author":"LP Kowalski","year":"2000","unstructured":"Kowalski LP, Bagietto R, Lara JR et al (2000) Prognostic significance of the distribution of neck node metastasis from oral carcinoma. Head Neck 22:207\u2013214","journal-title":"Head Neck"},{"key":"689_CR68","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0901-5027(99)80158-1","volume":"28","author":"S Shingaki","year":"1999","unstructured":"Shingaki S, Nomura T, Takada M et al (1999) The impact of extranodal spread of lymph node metastases in patients with oral cancer. Int J Oral Maxillofac Surg 28:279\u2013284","journal-title":"Int J Oral Maxillofac Surg"},{"key":"689_CR69","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1056\/NEJMoa032646","volume":"350","author":"JS Cooper","year":"2004","unstructured":"Cooper JS, Pajak TF, Forastiere AA et al (2004) Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 350:1937\u20131944","journal-title":"N Engl J Med"},{"key":"689_CR70","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1056\/NEJMoa032641","volume":"350","author":"J Bernier","year":"2004","unstructured":"Bernier J, Domenge C, Ozsahin M et al (2004) Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 350:1945\u20131952","journal-title":"N Engl J Med"},{"key":"689_CR71","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0301-0503(85)80064-3","volume":"13","author":"S Ozeki","year":"1985","unstructured":"Ozeki S, Tashiro H, Okamoto M et al (1985) Metastasis to the lingual lymph node in carcinoma of the tongue. J Maxillofac Surg 13:277\u2013281","journal-title":"J Maxillofac Surg"},{"key":"689_CR72","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1093\/jjco\/hyp001","volume":"39","author":"M Ando","year":"2009","unstructured":"Ando M, Asai M, Asakage T et al (2009) Metastatic neck diseases beyond the limits of a neck dissection: attention to the \u2018para-hyoid\u2019 area in T1\/2 oral tongue cancer. Jpn J Clin Oncol 39:231\u2013236","journal-title":"Jpn J Clin Oncol"},{"issue":"11","key":"689_CR73","doi-asserted-by":"crossref","first-page":"e79766","DOI":"10.1371\/journal.pone.0079766","volume":"8","author":"JR Tseng","year":"2013","unstructured":"Tseng JR, Ho TY, Lin CY et al (2013) Clinical outcomes of patients with oral cavity squamous cell carcinoma and retropharyngeal lymph node metastasis identified by FDG PET\/CT. PLoS One 8(11):e79766","journal-title":"PLoS One"},{"key":"689_CR74","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1001\/archotol.130.2.169","volume":"130","author":"ND Gross","year":"2004","unstructured":"Gross ND, Ellingson TW, Wax MK et al (2004) Impact of retropharyngeal lymph node metastasis in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 130:169\u2013173","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"689_CR75","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/j.ijom.2009.04.015","volume":"38","author":"M Umeda","year":"2009","unstructured":"Umeda M, Shigeta T, Takahashi H et al (2009) Metastasis to the lateral retropharyngeal lymph node from squamous cell carcinoma of the oral cavity: report of three cases. Int J Oral Maxillofac Surg 38:1004\u20131008","journal-title":"Int J Oral Maxillofac Surg"},{"key":"689_CR76","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/hed.2880160212","volume":"16","author":"Y Hasegawa","year":"1994","unstructured":"Hasegawa Y, Matsuura H (1994) Retropharyngeal node dissection in cancer of the oropharynx and hypopharynx. Head Neck 16:173\u2013180","journal-title":"Head Neck"},{"issue":"Suppl 2","key":"689_CR77","doi-asserted-by":"crossref","first-page":"S56","DOI":"10.1016\/S0385-8146(85)80030-4","volume":"12","author":"K Omura","year":"1985","unstructured":"Omura K, Shimada F, Takemiya S (1985) Dissection of parapharyngeal space in head and neck cancer. Auris Nasus Larynx 12(Suppl 2):S56\u2013S60","journal-title":"Auris Nasus Larynx"},{"key":"689_CR78","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1200\/JCO.2003.04.171","volume":"21","author":"J Huang","year":"2003","unstructured":"Huang J, Barbera L, Brouwers M et al (2003) Does delay in starting treatment affect the outcomes of radiotherapy? A systematic review. J Clin Oncol 21:555\u2013563","journal-title":"J Clin Oncol"},{"key":"689_CR79","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0360-3016(97)00092-8","volume":"38","author":"KT Robbins","year":"1997","unstructured":"Robbins KT, Kumar P, Regine WF et al (1997) Efficacy of targeted supradose cisplatin and concomitant radiation therapy for advanced head and neck cancer: the Memphis experience. Int J Radiat Oncol Biol Phys 38:263\u2013271","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"689_CR80","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.3109\/00016489.2012.684702","volume":"132","author":"T Furusaka","year":"2012","unstructured":"Furusaka T, Asakawa T, Tanaka A et al (2012) Efficacy of multidrug superselective intra-arterial chemotherapy (docetaxel, cisplatin, and 5-fluorouracil) using the Seldinger technique for tongue cancer. Acta Otolaryngol 132:1108\u20131114","journal-title":"Acta Otolaryngol"},{"key":"689_CR81","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/S1368-8375(98)00018-9","volume":"34","author":"I Tohnai","year":"1998","unstructured":"Tohnai I, Fuwa N, Hayashi Y et al (1998) New superselective intra-arterial infusion via superficial temporal artery for cancer of the tongue and tumour tissue platinum concentration after carboplatin (CBDCA) infusion. Oral Oncol 34:387\u2013390","journal-title":"Oral Oncol"},{"key":"689_CR82","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1016\/j.ijrobp.2010.01.011","volume":"79","author":"K Mitsudo","year":"2011","unstructured":"Mitsudo K, Shigetomi T, Fujimoto Y et al (2011) Organ preservation with daily concurrent chemoradiotherapy using superselective intra-arterial infusion via a superficial temporal artery for T3 and T4 head and neck cancer. Int J Radiat Oncol Biol Phys 79:1428\u20131435","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"689_CR83","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/sj.bjc.6601171","volume":"89","author":"IH Chen","year":"2003","unstructured":"Chen IH, Chang JT, Liao CT et al (2003) Prognostic significance of EGFR and Her-2 in oral cavity cancer in betel quid prevalent area cancer prognosis. Br J Cancer 89:681\u2013686","journal-title":"Br J Cancer"},{"key":"689_CR84","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1056\/NEJMoa053422","volume":"354","author":"JA Bonner","year":"2006","unstructured":"Bonner JA, Harari PM, Giralt J et al (2006) Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 354:567\u2013578","journal-title":"N Engl J Med"}],"container-title":["International Journal of Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10147-014-0689-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10147-014-0689-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10147-014-0689-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T02:18:34Z","timestamp":1746152314000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10147-014-0689-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,1]]},"references-count":84,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["689"],"URL":"https:\/\/doi.org\/10.1007\/s10147-014-0689-z","relation":{},"ISSN":["1341-9625","1437-7772"],"issn-type":[{"value":"1341-9625","type":"print"},{"value":"1437-7772","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,1]]}}}