{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:40:28Z","timestamp":1792100428844,"version":"4.4.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2019,11,7]],"date-time":"2019-11-07T00:00:00Z","timestamp":1573084800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,11,7]],"date-time":"2019-11-07T00:00:00Z","timestamp":1573084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Clin Oncol"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1007\/s10147-019-01573-0","type":"journal-article","created":{"date-parts":[[2019,11,7]],"date-time":"2019-11-07T09:04:32Z","timestamp":1573117472000},"page":"765-773","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Impact of microscopically margin-positive resection on survival in children with hepatoblastoma after hepatectomy: a retrospective cohort study"],"prefix":"10.1007","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8092-6687","authenticated-orcid":false,"given":"Xianghai","family":"Ren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Diao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,11,7]]},"reference":[{"key":"1573_CR1","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.jcma.2017.11.012","volume":"81","author":"GY Hung","year":"2018","unstructured":"Hung GY, Lin LY, Yu TY et al (2018) Hepatoblastoma incidence in Taiwan: a population-based study. J Chin Med Assoc 81:541\u2013547","journal-title":"J Chin Med Assoc"},{"key":"1573_CR2","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1053\/j.sempedsurg.2016.09.002","volume":"25","author":"DC Aronson","year":"2016","unstructured":"Aronson DC, Meyers RL (2016) Malignant tumors of the liver in children. Sem Pedatr Surg 25:265\u2013275","journal-title":"Sem Pedatr Surg"},{"key":"1573_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00383-010-2708-0","volume":"27","author":"T Hishiki","year":"2011","unstructured":"Hishiki T, Matsunaga T, Sasaki F et al (2011) Outcome of hepatoblastomas treated using the Japanese Study Group for Pediatric Liver Tumor (JPLT) protocol-2: report from the JPLT. Pediatr Surg Int 27:1\u20138","journal-title":"Pediatr Surg Int"},{"key":"1573_CR4","doi-asserted-by":"publisher","first-page":"493","DOI":"10.2741\/e395","volume":"4","author":"B Haeberle","year":"2012","unstructured":"Haeberle B, Dv S (2012) Treatment of hepatoblastoma in the German cooperative pediatric liver tumor studies. Front Biosci 4:493\u2013498","journal-title":"Front Biosci"},{"key":"1573_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2019.01.036","author":"AS Fahy","year":"2019","unstructured":"Fahy AS, Shaikh F, Gerstle JT (2019) Multifocal hepatoblastoma: what is the risk of recurrent disease in the remnant liver? J Pediatr Surg. https:\/\/doi.org\/10.1016\/j.jpedsurg.2019.01.036","journal-title":"J Pediatr Surg"},{"key":"1573_CR6","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.canlet.2016.02.051","volume":"375","author":"XJ Yuan","year":"2016","unstructured":"Yuan XJ, Wang HM, Jiang H et al (2016) Multidisciplinary effort in treating children with hepatoblastoma in China. Cancer Lett 375:39\u201346","journal-title":"Cancer Lett"},{"key":"1573_CR7","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1002\/cncr.10632","volume":"95","author":"J Fuchs","year":"2002","unstructured":"Fuchs J, Rydzynski J, Dietrich VS et al (2002) Pretreatment prognostic factors and treatment results in children with hepatoblastoma: a report from the German Cooperative Pediatric Liver Tumor Study HB 94. Cancer 95:172\u2013182","journal-title":"Cancer"},{"key":"1573_CR8","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1001\/jamasurg.2015.1847","volume":"150","author":"TA Pham","year":"2015","unstructured":"Pham TA, Gallo AM, Concepcion W et al (2015) Effect of liver transplant on long-term disease-free survival in children with hepatoblastoma and hepatocellular cancer. JAMA Surg 150:1150\u20131158","journal-title":"JAMA Surg"},{"key":"1573_CR9","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1097\/MOP.0000000000000042","volume":"26","author":"RL Meyers","year":"2014","unstructured":"Meyers RL, Tiao G, De Goyet JD et al (2014) Hepatoblastoma state of the art: pre-treatment extent of disease, surgical resection guidelines and the role of liver transplantation. Curr Opin Pediatr 26:29\u201336","journal-title":"Curr Opin Pediatr"},{"key":"1573_CR10","first-page":"1","volume":"48","author":"AJ Towbin","year":"2018","unstructured":"Towbin AJ, Meyers RL, Woodley H et al (2018) 2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT). Pediatr Radiol 48:1\u201319","journal-title":"Pediatr Radiol"},{"key":"1573_CR11","doi-asserted-by":"publisher","first-page":"e27383","DOI":"10.1002\/pbc.27383","volume":"65","author":"H Uchida","year":"2018","unstructured":"Uchida H, Sakamoto S, Sasaki K et al (2018) Surgical treatment strategy for advanced hepatoblastoma: resection versus transplantation. Pediatr Blood Cancer 65:e27383","journal-title":"Pediatr Blood Cancer"},{"key":"1573_CR12","doi-asserted-by":"publisher","first-page":"1973","DOI":"10.1016\/j.jpedsurg.2008.05.031","volume":"43","author":"M Browne","year":"2008","unstructured":"Browne M, Sher D, Grant D et al (2008) Survival after liver transplantation for hepatoblastoma: a 2-center experience. J Pediatr Surg 43:1973\u20131981","journal-title":"J Pediatr Surg"},{"key":"1573_CR13","doi-asserted-by":"publisher","first-page":"1614","DOI":"10.1002\/lt.21586","volume":"14","author":"W Faraj","year":"2008","unstructured":"Faraj W, Dar F, Marangoni G et al (2008) Liver transplantation for hepatoblastoma. Liver Transpl 14:1614\u20131619","journal-title":"Liver Transpl"},{"key":"1573_CR14","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1097\/SLA.0000000000001936","volume":"266","author":"J Fuchs","year":"2017","unstructured":"Fuchs J, Cavdar S, Blumenstock G et al (2017) POST-TEXT III and IV hepatoblastoma: extended hepatic resection avoids liver transplantation in selected cases. Ann Surg 266:318\u2013323","journal-title":"Ann Surg"},{"key":"1573_CR15","doi-asserted-by":"publisher","first-page":"1976","DOI":"10.1002\/cncr.25722","volume":"117","author":"TB Lautz","year":"2011","unstructured":"Lautz TB, Ben-Ami T, Tantemsapya N et al (2011) Successful nontransplant resection of POST-TEXT III and IV hepatoblastoma. Cancer 117:1976\u20131983","journal-title":"Cancer"},{"key":"1573_CR16","doi-asserted-by":"publisher","first-page":"2194","DOI":"10.1016\/j.jpedsurg.2012.09.006","volume":"47","author":"T Tajiri","year":"2012","unstructured":"Tajiri T, Kimura O, Fumino S et al (2012) Surgical strategies for unresectable hepatoblastomas. J Pediatr Surg 47:2194\u20132198","journal-title":"J Pediatr Surg"},{"key":"1573_CR17","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s00247-006-0361-5","volume":"37","author":"DJ Roebuck","year":"2007","unstructured":"Roebuck DJ, Aronson D, Clapuyt P et al (2007) 2005 PRETEXT: a revised staging system for primary malignant liver tumours of childhood developed by the SIOPEL group. Pediatr Radiol 37:123\u2013132","journal-title":"Pediatr Radiol"},{"key":"1573_CR18","doi-asserted-by":"publisher","first-page":"2584","DOI":"10.1200\/JCO.2009.22.4857","volume":"28","author":"Z J\u00f3zsef","year":"2010","unstructured":"J\u00f3zsef Z, Maibach R, Shafford E et al (2010) Successful treatment of childhood high-risk hepatoblastoma with dose-intensive multiagent chemotherapy and surgery: final results of the SIOPEL-3HR study. J Clin Oncol 28:2584\u20132590","journal-title":"J Clin Oncol"},{"key":"1573_CR19","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1038\/modpathol.2013.80","volume":"27","author":"D L\u00f3pez-Terrada","year":"2014","unstructured":"L\u00f3pez-Terrada D, Alaggio R, de D\u00e1vila MT et al (2014) Towards an international pediatric liver tumor consensus classification: proceedings of the Los Angeles COG liver tumors symposium. Mod Pathol 27:472\u2013491","journal-title":"Mod Pathol"},{"key":"1573_CR20","doi-asserted-by":"publisher","first-page":"1533","DOI":"10.1016\/j.ejso.2014.07.033","volume":"40","author":"GL Qiao","year":"2014","unstructured":"Qiao GL, Li L, Cheng W et al (2014) Predictors of survival after resection of children with hepatoblastoma: a single Asian center experience. Eur J Surg Oncol 40:1533\u20131539","journal-title":"Eur J Surg Oncol"},{"key":"1573_CR21","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.ejca.2018.10.013","volume":"106","author":"DC Aronson","year":"2019","unstructured":"Aronson DC, Weeda VB, Maibach R et al (2019) Microscopically positive resection margin after hepatoblastoma resection: what is the impact on prognosis? A Childhood Liver Tumours Strategy Group (SIOPEL) report. Eur J Cancer 106:126\u2013132","journal-title":"Eur J Cancer"},{"key":"1573_CR22","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/S1470-2045(16)30598-8","volume":"18","author":"RL Meyers","year":"2017","unstructured":"Meyers RL, Maibach R, Hiyama E et al (2017) Risk-stratified staging in paediatric hepatoblastoma: a unified analysis from the Children's Hepatic tumors International Collaboration. Lancet Oncol 18:122\u2013131","journal-title":"Lancet Oncol"},{"key":"1573_CR23","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.ejca.2015.09.023","volume":"52","author":"P Czauderna","year":"2016","unstructured":"Czauderna P, Haeberle B, Hiyama E et al (2016) The Children\u2019s Hepatic tumors International Collaboration (CHIC): Novel global rare tumor database yields new prognostic factors in hepatoblastoma and becomes a research model. Eur J Cancer 52:92\u2013101","journal-title":"Eur J Cancer"},{"key":"1573_CR24","doi-asserted-by":"publisher","first-page":"2360","DOI":"10.1002\/cncr.30591","volume":"123","author":"HM Katzenstein","year":"2017","unstructured":"Katzenstein HM, Furman WL, Malogolowkin MH et al (2017) Upfront window vincristine\/irinotecan treatment of high-risk hepatoblastoma: a report from the Children\u2019s Oncology Group AHEP0731 study committee. Cancer 123:2360\u20132367","journal-title":"Cancer"},{"key":"1573_CR25","doi-asserted-by":"publisher","first-page":"e26249","DOI":"10.1002\/pbc.26249","volume":"64","author":"N Shanmugam","year":"2017","unstructured":"Shanmugam N, Scott JX, Kumar V et al (2017) Multidisciplinary management of hepatoblastoma in children: experience from a developing country. Pediatr Blood Cancer 64:e26249","journal-title":"Pediatr Blood Cancer"},{"key":"1573_CR26","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1097\/SLA.0b013e31818a07f1","volume":"248","author":"RJD Haas","year":"2008","unstructured":"Haas RJD, Wicherts DA, Flores E et al (2008) R1 resection by necessity for colorectal liver metastases is it still a contraindication to surgery? Ann Surg 248:626\u2013637","journal-title":"Ann Surg"},{"key":"1573_CR27","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1002\/lt.23803","volume":"20","author":"S Sakamoto","year":"2014","unstructured":"Sakamoto S, Kasahara M, Mizuta K et al (2014) Nationwide survey of the outcomes of living donor liver transplantation for hepatoblastoma in Japan. Liver Transpl 20:333\u2013346","journal-title":"Liver Transpl"},{"key":"1573_CR28","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1097\/PAS.0b013e3181ce5f1e","volume":"34","author":"LL Wang","year":"2010","unstructured":"Wang LL, Filippi RZ, Zurakowski D et al (2010) Effects of neoadjuvant chemotherapy on hepatoblastoma: a morphologic and immunohistochemical study. Am J Surg Pathol 34:287\u2013299","journal-title":"Am J Surg Pathol"},{"key":"1573_CR29","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1002\/pbc.24038","volume":"59","author":"R Venkatramani","year":"2012","unstructured":"Venkatramani R, Wang L, Malvar J et al (2012) Tumor necrosis predicts survival following neo-adjuvant chemotherapy for hepatoblastoma. Pediatr Blood Cancer 59:493\u2013498","journal-title":"Pediatr Blood Cancer"},{"key":"1573_CR30","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1016\/S1470-2045(13)70272-9","volume":"14","author":"Z J\u00f3zsef","year":"2013","unstructured":"J\u00f3zsef Z, Laurence B, Penelope B et al (2013) Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study. Lancet Oncol 14:834\u2013842","journal-title":"Lancet Oncol"}],"container-title":["International Journal of Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10147-019-01573-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10147-019-01573-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10147-019-01573-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,3]],"date-time":"2022-10-03T21:46:28Z","timestamp":1664833588000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10147-019-01573-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,7]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["1573"],"URL":"https:\/\/doi.org\/10.1007\/s10147-019-01573-0","relation":{},"ISSN":["1341-9625","1437-7772"],"issn-type":[{"value":"1341-9625","type":"print"},{"value":"1437-7772","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,7]]},"assertion":[{"value":"8 August 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 November 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 November 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}