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Gill was Clinical Director of Renishaw Plc. till 2020 and is a Director of XPEAD Ltd. No other author declares any conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Approval for this study was obtained from the Institutional Review Board of Harley Street Children\u2019s Hospital in London, United Kingdom, and was compliant with the 1964 Helsinki declaration and its later amendments. 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